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Select item 111602291.

Expression of short‐form caspase 8 correlates with decreased sensitivity to Fas‐mediated apoptosis in neuroblastoma cells

Rodrick R. Kisenge, Hidemi Toyoda, Jian Kang, Shigeki Tanaka, Hatsumi Yamamoto, Eiichi Azuma, Yoshihiro Komada

Cancer Sci. 2003 Jul; 94(7): 598–605. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2003.tb01489.x

PMCID:: PMC11160229

Abstract Article PDF–504K

Select item 111589592.

Modulation of RIP1 ubiquitylation and distribution by MeBS to sensitize cancer cells to tumor necrosis factor α‐induced apoptosis

Seungseob Kim, Nobumichi Ohoka, Keiichiro Okuhira, Kimie Sai, Tomoko Nishimaki‐Mogami, Mikihiko Naito

Cancer Sci. 2010 Nov; 101(11): 2425–2429. Published online 2010 Jul 31. doi: 10.1111/j.1349-7006.2010.01697.x

PMCID:: PMC11158959

Abstract Article PDF–365K

Select item 111586153.

DNMT1 and DNMT3b silencing sensitizes human hepatoma cells to TRAIL‐mediated apoptosis via up‐regulation of TRAIL‐R2/DR5 and caspase‐8

Satoshi Kurita, Hajime Higuchi, Yoshimasa Saito, Nobuhiro Nakamoto, Hiromasa Takaishi, Shinichiro Tada, Hidetsugu Saito, Gregory J. Gores, Toshifumi Hibi

Cancer Sci. 2010 Jun; 101(6): 1431–1439. Published online 2010 Mar 13. doi: 10.1111/j.1349-7006.2010.01565.x

PMCID:: PMC11158615

Abstract Article PDF–539K

Select item 110742994.

Deciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis

Chao-Yu Yang, Chia-I Lien, Yi-Chun Tseng, Yi-Fan Tu, Arkadiusz W. Kulczyk, Yen-Chen Lu, Yin-Ting Wang, Tsung-Wei Su, Li-Chung Hsu, Yu-Chih Lo, Su-Chang Lin

Nat Commun. 2024; 15: 3791. Published online 2024 May 6. doi: 10.1038/s41467-024-47990-2

PMCID:: PMC11074299

Abstract Article PDF–5.7M

Select item 108473355.

TNF and IFNγ-induced cell death requires IRF1 and ELAVL1 to promote CASP8 expression

Buhao Deng, Jingyi Wang, Tingyun Yang, Zhao Deng, Jiafan Yuan, Bohan Zhang, Zhen Zhou, Fang Chen, Lu Fang, Chengzhi Liang, Bo Yan, Youwei Ai

J Cell Biol. 2024 Mar 4; 223(3): e202305026. Published online 2024 Feb 6. doi: 10.1083/jcb.202305026

PMCID:: PMC10847335

Abstract Article PDF–8.1M

Select item 107713356.

Multidimensional Analysis of PANoptosis-Related Molecule CASP8: Prognostic Significance, Immune Microenvironment Effect, and Therapeutic Implications in Hepatocellular Carcinoma

Fei Peng, Fang Zhu, Baodi Cao, Liang Peng

Genet Res (Camb) 2023; 2023: 2406193. Published online 2023 Dec 30. doi: 10.1155/2023/2406193

PMCID:: PMC10771335

Abstract Article PDF–6.2M

Select item 106763977.

Caspase-8 activation by cigarette smoke induces pro-inflammatory cell death of human macrophages exposed to lipopolysaccharide

Marta Cristaldi, Marco Buscetta, Maura Cimino, Agnese La Mensa, Maria Rita Giuffrè, Luigi Fiore, Claudia Carcione, Fabio Bucchieri, Francesca Rappa, Claudia Coronnello, Nicolina Sciaraffa, Santina Amato, Tommaso Silvano Aronica, Giovanna Lo Iacono, Alessandro Bertani, Elisabetta Pace, Chiara Cipollina

Cell Death Dis. 2023 Nov; 14(11): 773. Published online 2023 Nov 25. doi: 10.1038/s41419-023-06318-6

PMCID:: PMC10676397

Abstract Article PDF–2.1M

Select item 106433628.

Circ_0004535/miR-1827/CASP8 network involved in type 2 diabetes mellitus with nonalcoholic fatty liver disease

Min Li, Ai Zeng, Xinle Tang, Hui Xu, Wei Xiong, Yanying Guo

Sci Rep. 2023; 13: 19807. Published online 2023 Nov 13. doi: 10.1038/s41598-023-47189-3

PMCID:: PMC10643362

Abstract Article PDF–5.1M

Select item 103093569.

Gene Polymorphisms in FAS (Rs3740286 and Rs4064) Are Involved in Endometriosis Development in Brazilian Women, but not those in CASP8 (rs13416436 and rs2037815)

Cristina Wide Pissetti, Sarah Cristina Sato Vaz Tanaka, Andrezza Cristina Cancian Hortolani, Alessandra Bernadete Trovó de Marqui

Rev Bras Ginecol Obstet. 2018 Aug; 40(8): 450–457. Published online 2018 Jul 23. doi: 10.1055/s-0038-1667183

PMCID:: PMC10309356

Abstract Article PDF–182K

Select item 1025778010.

Apoptosis of pro-B lymphocytes induced by NR4A1 activation in the presence of gingival fibroblast exosomes and TNFα, caspase 8, STAT3, and Akt pathways modulators

Carmen Amititeloaie, Liliana Chelaru, Gabriela Luminiţa Geleţu, Anca Sava, Alexandra Jităreanu, Andreea Mihaela Tibeică, Marcel Costuleanu

Rom J Morphol Embryol. 2023 Jan-Mar; 64(1): 35–40. Published online 2023 Mar 31. doi: 10.47162/RJME.64.1.04

PMCID:: PMC10257780

Abstract Article PDF–770K

Select item 1024438311.

IKK-mediated TRAF6 and RIPK1 interaction stifles cell death complex assembly leading to the suppression of TNF-α-induced cell death

Choong-Sil Lee, Gyuho Hwang, Young Woo Nam, Chi Hyun Hwang, Jaewhan Song

Cell Death Differ. 2023 Jun; 30(6): 1575–1584. Published online 2023 Apr 21. doi: 10.1038/s41418-023-01161-w

PMCID:: PMC10244383

Abstract Article PDF–2.8M

Select item 1023742212.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1015574813.

Bidirectional Mendelian Randomisation Analysis Provides Evidence for the Causal Involvement of Dysregulation of CXCL9, CCL11 and CASP8 in the Pathogenesis of Ulcerative Colitis

Jie Chen, Yajing Zhou, Yuhao Sun, Shuai Yuan, Rahul Kalla, Jing Sun, Jianhui Zhao, Lijuan Wang, Xuejie Chen, Xuan Zhou, Siqi Dai, Yu Zhang, Gwo-tzer Ho, Dajing Xia, Qian Cao, Zhanju Liu, Susanna C Larsson, Xiaoyan Wang, Kefeng Ding, Jonas Halfvarson, Xue Li, Evropi Theodoratou, Jack Satsangi

J Crohns Colitis. 2023 May; 17(5): 777–785. Published online 2022 Dec 28. doi: 10.1093/ecco-jcc/jjac191

PMCID:: PMC10155748

Abstract Article PDF–736K

Select item 1012768514.

MLKL-Driven Inflammasome Activation and Caspase-8 Mediate Inflammatory Cell Death in Influenza A Virus Infection

Xuqiu Lei, Yongzhi Chen, Egil Lien, Katherine A. Fitzgerald

mBio. 2023 Mar-Apr; 14(2): e00110-23. Published online 2023 Feb 28. doi: 10.1128/mbio.00110-23

PMCID:: PMC10127685

Abstract Article PDF–1.2M

Select item 1007163415.

Genetic contribution of caspase-8 variants and haplotypes to breast cancer risk and prognosis: a case-control study in Iran

Fahimeh Afzaljavan, Elham Vahednia, Matineh Barati Bagherabad, Fatemeh Vakili, Atefeh Moezzi, Azar Hosseini, Fatemeh Homaei Shandiz, Mohammad Mahdi Kooshyar, Mohammadreza Nassiri, Alireza Pasdar

BMC Med Genomics. 2023; 16: 72. Published online 2023 Apr 4. doi: 10.1186/s12920-023-01484-0

PMCID:: PMC10071634

Abstract Article PDF–1.1M

Select item 1006833816.

Triglyceride induces DNA damage leading to monocyte death by activating caspase-2 and caspase-8

Byung Chul Jung, Hyun-Kyung Kim, Sung Hoon Kim, Yoon Suk Kim

BMB Rep. 2023 Mar 31; 56(3): 166–171. Published online 2023 Feb 2. doi: 10.5483/BMBRep.2022-0201

PMCID:: PMC10068338

Abstract Article PDF–4.6M

Select item 997596117.

Caspase‐8‐driven apoptotic and pyroptotic crosstalk causes cell death and IL‐1β release in X‐linked inhibitor of apoptosis (XIAP) deficiency

Sebastian A Hughes, Meng Lin, Ashley Weir, Bing Huang, Liya Xiong, Ngee Kiat Chua, Jiyi Pang, Jascinta P Santavanond, Rochelle Tixeira, Marcel Doerflinger, Yexuan Deng, Chien‐Hsiung Yu, Natasha Silke, Stephanie A Conos, Daniel Frank, Daniel S Simpson, James M Murphy, Kate E Lawlor, Jaclyn S Pearson, John Silke, Marc Pellegrini, Marco J Herold, Ivan K H Poon, Seth L Masters, Mingsong Li, Qin Tang, Yuxia Zhang, Maryam Rashidi, Lanlan Geng, James E Vince

EMBO J. 2023 Mar; 42(5): e110468. Published online 2023 Jan 17. doi: 10.15252/embj.2021110468

PMCID:: PMC9975961

Abstract Article PDF–4.4M

Select item 997146118.

The Effect of Caspase 8, 9 Gene Polymorphisms on Non-Hodgkin Lymphoma Susceptibility and Clinical/Pathological Features

Fatemeh Barati, Gholamreza Bahari, Anoosha Asadi, Alireza Nakhaee, Seyed-Mehdi Hashemi, Mohsen Taheri, Mohammad Hashemi

Asian Pac J Cancer Prev. 2022 Dec; 23(12): 4339–4346. doi: 10.31557/APJCP.2022.23.12.4339

PMCID:: PMC9971461

Abstract Article PDF–454K

Select item 995046319.

Caspase-8 as a novel mediator linking Src kinase signaling to enhanced glioblastoma malignancy

Claudia Contadini, Alessandra Ferri, Marta Di Martile, Claudia Cirotti, Donatella Del Bufalo, Francesca De Nicola, Matteo Pallocca, Maurizio Fanciulli, Francesca Sacco, Gloria Donninelli, Alessia Capone, Elisabetta Volpe, Nadine Keller, Shunichiro Miki, Daisuke Kawauchi, Dwayne Stupack, Frank Furnari, Daniela Barilà

Cell Death Differ. 2023 Feb; 30(2): 417–428. Published online 2022 Dec 2. doi: 10.1038/s41418-022-01093-x

PMCID:: PMC9950463

Abstract Article PDF–3.9M

Select item 988406720.

Evaluation of both expression and serum protein levels of caspase-8 and mitogen-activated protein kinase 1 genes in patients with different severities of COVID-19 infection

Murat Acat, Pınar Yıldız Gülhan, Recep Eröz, Ayşegül Ertınmaz Özkan, Oğuzhan Koca, Caner Çınar

Mol Biol Rep. 2023; 50(4): 3241–3248. Published online 2023 Jan 28. doi: 10.1007/s11033-023-08244-4

PMCID:: PMC9884067

Abstract Article PDF–984K

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