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Select item 108664301.

Circ0060467 sponges miR-6805 to promote hepatocellular carcinoma progression through regulating AIFM2 and GPX4 expression

Ye-Ru Tan, Bao-Hong Jiang, Wen-Jie Feng, Zhi-Long He, Yi-Ling Jiang, Yi Xun, Xiao-Ping Wu, Yue-Hua Li, Hong-Bo Zhu

Aging (Albany NY) 2024 Jan 31; 16(2): 1796–1807. Published online 2024 Jan 19. doi: 10.18632/aging.205460

PMCID:: PMC10866430

Abstract Article PDF–1.3M

Select item 105824652.

TRIM21‐Promoted FSP1 Plasma Membrane Translocation Confers Ferroptosis Resistance in Human Cancers

Jun Gong, Yuhui Liu, Wenjia Wang, Ruizhi He, Qilong Xia, Lin Chen, Chunle Zhao, Yang Gao, Yongkang Shi, Yu Bai, Yangwei Liao, Qi Zhang, Feng Zhu, Min Wang, Xu Li, Renyi Qin

Adv Sci (Weinh) 2023 Oct; 10(29): 2302318. Published online 2023 Aug 16. doi: 10.1002/advs.202302318

PMCID:: PMC10582465

Abstract Article PDF–8.3M

Select item 104972523.

Sorafenib induces ferroptosis by promoting TRIM54-mediated FSP1 ubiquitination and degradation in hepatocellular carcinoma

Man-ru Liu, Ce Shi, Qiu-ya Song, Meng-jie Kang, Xin Jiang, Hui Liu, Dong-sheng Pei

Hepatol Commun. 2023 Oct; 7(10): e0246. Published online 2023 Sep 11. doi: 10.1097/HC9.0000000000000246

PMCID:: PMC10497252

Abstract Article PDF–1.2M

Select item 103383364.

Phase separation of FSP1 promotes ferroptosis

Toshitaka Nakamura, Clara Hipp, André Santos Dias Mourão, Jan Borggräfe, Maceler Aldrovandi, Bernhard Henkelmann, Jonas Wanninger, Eikan Mishima, Elena Lytton, David Emler, Bettina Proneth, Michael Sattler, Marcus Conrad

Nature. 2023; 619(7969): 371–377. Published online 2023 Jun 28. doi: 10.1038/s41586-023-06255-6

PMCID:: PMC10338336

Abstract Article PDF–37M

Select item 102374225.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101192826.

Molecular characterization of AIFM2/FSP1 inhibition by iFSP1-like molecules

Thamara Nishida Xavier da Silva, Clemens Schulte, Ariane Nunes Alves, Hans Michael Maric, José Pedro Friedmann Angeli

Cell Death Dis. 2023 Apr; 14(4): 281. Published online 2023 Apr 21. doi: 10.1038/s41419-023-05787-z

PMCID:: PMC10119282

Abstract Article PDF–3.7M

Select item 99504767.

Elevated FSP1 protects KRAS-mutated cells from ferroptosis during tumor initiation

Fabienne Müller, Jonathan K. M. Lim, Christina M. Bebber, Eric Seidel, Sofya Tishina, Alina Dahlhaus, Jenny Stroh, Julia Beck, Fatma Isil Yapici, Keiko Nakayama, Lucia Torres Fernández, Johannes Brägelmann, Gabriel Leprivier, Silvia von Karstedt

Cell Death Differ. 2023 Feb; 30(2): 442–456. Published online 2022 Nov 29. doi: 10.1038/s41418-022-01096-8

PMCID:: PMC9950476

Abstract Article PDF–4.6M

Select item 99293288.

A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase

Da-Yun Jin, Xuejie Chen, Yizhou Liu, Craig M. Williams, Lars C. Pedersen, Darrel W. Stafford, Jian-Ke Tie

Nat Commun. 2023; 14: 828. Published online 2023 Feb 14. doi: 10.1038/s41467-023-36446-8

PMCID:: PMC9929328

Abstract Article PDF–2.1M

Select item 97597599.

N‐acetyltransferase 10 promotes colon cancer progression by inhibiting ferroptosis through N4‐acetylation and stabilization of ferroptosis suppressor protein 1 (FSP1) mRNA

Xiao Zheng, Qi Wang, You Zhou, Dachuan Zhang, Yiting Geng, Wenwei Hu, Changping Wu, Yufang Shi, Jingting Jiang

Cancer Commun (Lond) 2022 Dec; 42(12): 1347–1366. Published online 2022 Oct 8. doi: 10.1002/cac2.12363

PMCID:: PMC9759759

Abstract Article PDF–4.8M

Select item 969204110.

HDLBP-stabilized lncFAL inhibits ferroptosis vulnerability by diminishing Trim69-dependent FSP1 degradation in hepatocellular carcinoma

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi

Redox Biol. 2022 Dec; 58: 102546. Published online 2022 Nov 19. doi: 10.1016/j.redox.2022.102546

PMCID:: PMC9692041

Abstract Article PDF–13M

Select item 940243211.

A non-canonical vitamin K cycle is a potent ferroptosis suppressor

Eikan Mishima, Junya Ito, Zijun Wu, Toshitaka Nakamura, Adam Wahida, Sebastian Doll, Wulf Tonnus, Palina Nepachalovich, Elke Eggenhofer, Maceler Aldrovandi, Bernhard Henkelmann, Ken-ichi Yamada, Jonas Wanninger, Omkar Zilka, Emiko Sato, Regina Feederle, Daniela Hass, Adriano Maida, André Santos Dias Mourão, Andreas Linkermann, Edward K. Geissler, Kiyotaka Nakagawa, Takaaki Abe, Maria Fedorova, Bettina Proneth, Derek A. Pratt, Marcus Conrad

Nature. 2022; 608(7924): 778–783. Published online 2022 Aug 3. doi: 10.1038/s41586-022-05022-3

PMCID:: PMC9402432

Abstract Article PDF–9.5M

Select item 889702212.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 857279213.

CircGFRA1 facilitates the malignant progression of HER‐2‐positive breast cancer via acting as a sponge of miR‐1228 and enhancing AIFM2 expression

Meiheban Bazhabayi, Xingsheng Qiu, Xing Li, Anli Yang, Wei Wen, Xiaoli Zhang, Xiangsheng Xiao, Rongfang He, Peng Liu

J Cell Mol Med. 2021 Nov; 25(21): 10248–10256. Published online 2021 Oct 20. doi: 10.1111/jcmm.16963

PMCID:: PMC8572792

Abstract Article PDF–1.1M

Select item 818479614.

FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells

Nadia Habel, Najla El-Hachem, Frédéric Soysouvanh, Hanene Hadhiri-Bzioueche, Serena Giuliano, Sophie Nguyen, Pavel Horák, Anne-Sophie Gay, Delphine Debayle, Nicolas Nottet, Guillaume Béranger, Brigitte Bressac-de Paillerets, Corine Bertolotto, Robert Ballotti

Cell Death Differ. 2021 Jun; 28(6): 1837–1848. Published online 2021 Jan 18. doi: 10.1038/s41418-020-00710-x

PMCID:: PMC8184796

Abstract Article PDF–2.4M

Select item 816503015.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 738172616.

ATF6 aggravates acinar cell apoptosis and injury by regulating p53/AIFM2 transcription in Severe Acute Pancreatitis

Jie-Hui Tan, Rong-Chang Cao, Lei Zhou, Zhi-Tao Zhou, Huo-Ji Chen, Jia Xu, Xue-Mei Chen, Yang-Chen Jin, Jia-Yu Lin, Jun-Ling Zeng, Shu-Ji Li, Min Luo, Guo-Dong Hu, Xiao-Bing Yang, Jin Jin, Guo-Wei Zhang

Theranostics. 2020; 10(18): 8298–8314. Published online 2020 Jul 9. doi: 10.7150/thno.46934

PMCID:: PMC7381726

Abstract Article PDF–6.4M

Select item 737208117.

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding

Duc T. Tran, Anita Pottekat, Saiful A. Mir, Salvatore Loguercio, Insook Jang, Alexandre Rosa Campos, Kathleen M. Scully, Reyhaneh Lahmy, Ming Liu, Peter Arvan, William E. Balch, Randal J. Kaufman, Pamela Itkin-Ansari

Diabetes. 2020 Aug; 69(8): 1723–1734. Published online 2020 May 26. doi: 10.2337/db20-0245

PMCID:: PMC7372081

Abstract Article PDF–2.0M

Select item 716998318.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 688316719.

The CoQ oxidoreductase FSP1 acts in parallel to GPX4 to inhibit ferroptosis

Kirill Bersuker, Joseph Hendricks, Zhipeng Li, Leslie Magtanong, Breanna Ford, Peter H. Tang, Melissa A. Roberts, Bingqi Tong, Thomas J. Maimone, Roberto Zoncu, Michael C. Bassik, Daniel K. Nomura, Scott J. Dixon, James A. Olzmann

Nature. Author manuscript; available in PMC 2020 Apr 21.

Published in final edited form as: Nature. 2019 Nov; 575(7784): 688–692. Published online 2019 Oct 21. doi: 10.1038/s41586-019-1705-2

PMCID:: PMC6883167

Abstract Article PDF–4.6M

Select item 642409820.

PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBPβ

Gunnar Dittmar, Daniel Perez Hernandez, Elisabeth Kowenz-Leutz, Marieluise Kirchner, Günther Kahlert, Radoslaw Wesolowski, Katharina Baum, Maria Knoblich, Maria Hofstätter, Arnaud Muller, Jana Wolf, Ulf Reimer, Achim Leutz

iScience. 2019 Mar 29; 13: 351–370. Published online 2019 Mar 1. doi: 10.1016/j.isci.2019.02.026

PMCID:: PMC6424098

Abstract Article PDF–11M

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