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Items: 1 to 20 of 277

1.
Oncogenic MYD88 mutations in lymphoma: novel insights and therapeutic possibilities
Alexander N. R. Weber, Yamel Cardona Gloria, Özcan Çınar, H. Christian Reinhardt, Antonio Pezzutto, Olaf-Oliver Wolz
Cancer Immunol Immunother. 2018 Nov; 67(11): 1797–1807. Published online 2018 Sep 11. doi: 10.1007/s00262-018-2242-9
PMCID:
PMC11028221
AbstractArticlePDF–2.2M
2.
The impact of MYD88 and PIM1 in mature large B-cell non-Hodgkin lymphomas: Defining element of their evolution and prognosis
Miruna Cristian, Mariana Așchie, Anca-Florentina Mitroi, Mariana Deacu, Mădălina Boșoteanu, Gabriela-Izabela Bălțătescu, Andreea-Georgiana Stoica, Anca-Antonela Nicolau, Manuela Enciu, Ana-Maria Crețu, Andreea-Daniela Caloian, Cristian-Ionuț Orășanu, Ionuț Poinăreanu
Medicine (Baltimore) 2024 Feb 9; 103(6): e36269. Published online 2024 Feb 9. doi: 10.1097/MD.0000000000036269
PMCID:
PMC10860999
AbstractArticlePDF–1.0M
3.
The Prevalence of MYD88 L265P and TNFAIP3 Mutations and Their Correlations with Clinico-Hematological Profile in Egyptian Patients with Diffuse Large B Cell Lymphoma
Osama Elbaz, Rana M. Shaat, Hasan A. Abd El Ghaffar, Sameh Shamaa, Hanaa M. Abdel-Masseih, Nahla Anber, Metwaly Ibrahim Mortada
Asian Pac J Cancer Prev. 2023; 24(7): 2485–2491. doi: 10.31557/APJCP.2023.24.7.2485
PMCID:
PMC10676502
AbstractArticlePDF–419K
4.
Paralog-specific signaling by IRAK1/4 maintains MyD88-independent functions in MDS/AML
Joshua Bennett, Chiharu Ishikawa, Puneet Agarwal, Jennifer Yeung, Avery Sampson, Emma Uible, Eric Vick, Lyndsey C. Bolanos, Kathleen Hueneman, Mark Wunderlich, Amal Kolt, Kwangmin Choi, Andrew Volk, Kenneth D. Greis, Jan Rosenbaum, Scott B. Hoyt, Craig J. Thomas, Daniel T. Starczynowski
Blood. 2023 Sep 14; 142(11): 989–1007. Published online 2023 May 16. doi: 10.1182/blood.2022018718
PMCID:
PMC10517216
AbstractArticle
5.
Thalidomide Alleviates Apoptosis, Oxidative Damage and Inflammation Induced by Pemphigus Vulgaris IgG in HaCat Cells and Neonatal Mice Through MyD88
Chunyan Luan, Zhipeng Lu, Juan Chen, Mengxing Chen, Ran Zhao, Xiaolan Li
Drug Des Devel Ther. 2023; 17: 2821–2839. Published online 2023 Sep 12. doi: 10.2147/DDDT.S407242
PMCID:
PMC10504907
AbstractArticlePDF–14M
6.
MyD88和TICAM1基因多态性及其交互作用与儿童社区获得性肺炎的关联研究
杨 勇, 杨 绥宇, 陈 宗波, 刘 俐
Zhongguo Dang Dai Er Ke Za Zhi. 2023 Aug 15; 25(8): 791–799. Chinese. doi: 10.7499/j.issn.1008-8830.2303062
PMCID:
PMC10484080
AbstractArticlePDF–1.1M
7.
The oncogenic human B-cell lymphoma MYD88 L265P mutation genocopies activation by phosphorylation at the Toll/interleukin-1 receptor (TIR) domain
Marthe Minderman, Hildo Lantermans, Carmen van der Zwaan, Arie J. Hoogendijk, Maartje van den Biggelaar, Marie José Kersten, Marcel Spaargaren, Steven T. Pals
Blood Cancer J. 2023 Dec; 13(1): 125. Published online 2023 Aug 18. doi: 10.1038/s41408-023-00896-6
PMCID:
PMC10435502
AbstractArticlePDF–2.4M
8.
SARS-CoV-2 ORF8 mediates signals in macrophages and monocytes through MyD88 independently of the IL-17 Receptor
Nicole O. Ponde, Karsen E. Shoger, Mst Shamima Khatun, Mrinal K. Sarkar, Ipsita Dey, Tiffany C. Taylor, Rylee N. Cisney, Samyuktha P. Arunkumar, Johann E. Gudjonsson, Jay K. Kolls, Rachel A. Gottschalk, Sarah L. Gaffen
J Immunol. Author manuscript; available in PMC 2024 Jul 15.
Published in final edited form as: J Immunol. 2023 Jul 15; 211(2): 252–260. doi: 10.4049/jimmunol.2300110
PMCID:
PMC10330444
AbstractArticlePDF–1.9M
9.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
10.
Human γδ T cells induce CD8+ T cell antitumor responses via antigen-presenting effect through HSP90-MyD88-mediated activation of JNK
Shengdong Wang, Hengyuan Li, Tao Chen, Hao Zhou, Wenkan Zhang, Nong Lin, Xiaohua Yu, Yu Lou, Binghao Li, Eloy Yinwang, Zenan Wang, Keyi Wang, Yucheng Xue, Hao Qu, Peng Lin, Hangxiang Sun, Wangsiyuan Teng, Haochen Mou, Xupeng Chai, Zhijian Cai, Zhaoming Ye
Cancer Immunol Immunother. 2023 Jun; 72(6): 1803–1821. Published online 2023 Jan 21. doi: 10.1007/s00262-023-03375-w
PMCID:
PMC10198898
AbstractArticlePDF–7.4M
11.
Prognostic impact of MYD88 and CXCR4 mutations assessed by droplet digital polymerase chain reaction in IgM monoclonal gammopathy of undetermined significance and smouldering Waldenström macroglobulinaemia
David F. Moreno, Mónica López‐Guerra, Sara Paz, Aina Oliver‐Caldés, Mari‐Pau Mena, Juan G. Correa, Anthony M. Battram, Miguel Osuna, Alfredo Rivas‐Delgado, Luis Gerardo Rodríguez‐Lobato, Oriol Cardús, Natalia Tovar, María Teresa Cibeira, Raquel Jiménez‐Segura, Joan Bladé, Laura Rosiñol, Dolors Colomer, Carlos Fernández de Larrea
Br J Haematol. 2023 Jan; 200(2): 187–196. Published online 2022 Oct 9. doi: 10.1111/bjh.18502
PMCID:
PMC10092069
AbstractArticlePDF–5.0M
12.
Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia
Ana García-García, Rebeca Pérez de Diego, Carlos Flores, Darawan Rinchai, Jordi Solé-Violán, Àngela Deyà-Martínez, Blanca García-Solis, José M. Lorenzo-Salazar, Elisa Hernández-Brito, Anna-Lisa Lanz, Leen Moens, Giorgia Bucciol, Mohamed Almuqamam, Joseph B. Domachowske, Elena Colino, Juan Luis Santos-Perez, Francisco M. Marco, Claudio Pignata, Aziz Bousfiha, Stuart E. Turvey, Stefanie Bauer, Filomeen Haerynck, Javier Gonzalo Ocejo-Vinyals, Francisco Lendinez, Seraina Prader, Nora Naumann-Bartsch, Jana Pachlopnik Schmid, Catherine M. Biggs, Kyla Hildebrand, Alexandra Dreesman, Miguel Ángel Cárdenes, Fatima Ailal, Ibtihal Benhsaien, Giuliana Giardino, Agueda Molina-Fuentes, Claudia Fortuny, Swetha Madhavarapu, Daniel H. Conway, Carolina Prando, Laire Schidlowski, María Teresa Martínez de Saavedra Álvarez, Rafael Alfaro, Felipe Rodríguez de Castro, ESID Registry Working Party, COVID Human Genetic Effort, Isabelle Meyts, Fabian Hauck, Anne Puel, Paul Bastard, Bertrand Boisson, Emmanuelle Jouanguy, Laurent Abel, Aurélie Cobat, Qian Zhang, Jean-Laurent Casanova, Laia Alsina, Carlos Rodríguez-Gallego
J Exp Med. 2023 May 1; 220(5): e20220170. Published online 2023 Mar 3. doi: 10.1084/jem.20220170
PMCID:
PMC9998661
AbstractArticlePDF–2.6M
13.
Genetic and Clinical Characteristics of Korean Chronic Lymphocytic Leukemia Patients with High Frequencies of MYD88 Mutations
Ari Ahn, Hoon Seok Kim, Tong-Yoon Kim, Jong-Mi Lee, Dain Kang, Haein Yu, Chae Yeon Lee, Yonggoo Kim, Ki-Seong Eom, Myungshin Kim
Int J Mol Sci. 2023 Feb; 24(4): 3177. Published online 2023 Feb 6. doi: 10.3390/ijms24043177
PMCID:
PMC9959581
AbstractArticlePDF–2.5M
14.
A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor
Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth
Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.
Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841
PMCID:
PMC9769698
AbstractArticlePDF–2.7M
15.
Adaptor protein MyD88 confers the susceptibility to stress via amplifying immune danger signals
Xia-Ping Yao, Jian Ye, Ting Feng, Feng-Chao Jiang, Ping Zhou, Fang Wang, Jian-Guo Chen, Peng-Fei Wu
Brain Behav Immun. 2023 Feb; 108: 204–220. Published online 2022 Dec 7. doi: 10.1016/j.bbi.2022.12.007
PMCID:
PMC9726649
AbstractArticlePDF–12M
16.
PAUF Induces Migration of Human Pancreatic Cancer Cells Exclusively via the TLR4/MyD88/NF-κB Signaling Pathway
So Eun Youn, Fen Jiang, Hye Yun Won, Da Eun Hong, Tae Heung Kang, Yun-Yong Park, Sang Seok Koh
Int J Mol Sci. 2022 Oct; 23(19): 11414. Published online 2022 Sep 27. doi: 10.3390/ijms231911414
PMCID:
PMC9570212
AbstractArticlePDF–3.9M
17.
Necroptosis of nucleus pulposus cells involved in intervertebral disc degeneration through MyD88 signaling
Hong Fan, Zhe Chen, Hai-Bin Tang, Le-Qun Shan, Zi-Yi Chen, Shi-Chang Liu, Yong-Yuan Zhang, Xin-Yu Guo, Hao Yang, Ding-Jun Hao
Front Endocrinol (Lausanne) 2022; 13: 994307. Published online 2022 Sep 21. doi: 10.3389/fendo.2022.994307
PMCID:
PMC9532572
AbstractArticlePDF–10M
18.
SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk
Valentina Lukinović, Simone Hausmann, Gael S. Roth, Clement Oyeniran, Tanveer Ahmad, Ning Tsao, Joshua R. Brickner, Alexandre G. Casanova, Florent Chuffart, Ana Morales Benitez, Jessica Vayr, Rebecca Rodell, Marianne Tardif, Pascal W.T.C. Jansen, Yohann Couté, Michiel Vermeulen, Pierre Hainaut, Pawel K. Mazur, Nima Mosammaparast, Nicolas Reynoird
Cancer Discov. 2022 Sep 2; 12(9): 2158–2179. Published online 2022 Jul 12. doi: 10.1158/2159-8290.CD-21-0205
PMCID:
PMC9437563
AbstractArticlePDF–9.5M
19.
Circular RNA MELK Promotes Chondrocyte Apoptosis and Inhibits Autophagy in Osteoarthritis by Regulating MYD88/NF-κB Signaling Axis through MicroRNA-497-5p
Yingchi Zhang, Rui Lu, Xiaojian Huang, Enzhi Yin, Yong Yang, Chengla Yi, Hongbo You, Xianzhou Song, Xuefeng Yuan
Contrast Media Mol Imaging. 2022; 2022: 7614497. Published online 2022 Jul 30. doi: 10.1155/2022/7614497
PMCID:
PMC9356867
AbstractArticlePDF–2.0M
20.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M

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