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Select item 109175491.

Aberrantly High FBXO31 Impairs Oocyte Quality in Premature Ovarian Insufficiency

Feiyan Zhao, Long Yan, Xuehan Zhao, Jiaqi Wu, Ying Fang, Zhimin Xin, Hongmei Wang, Xiaokui Yang

Aging Dis. 2024 Apr 1; 15(2): 804–823. Published online 2024 Apr 1. doi: 10.14336/AD.2023.0809

PMCID:: PMC10917549

Abstract Article PDF–4.9M

Select item 107869072.

FBXO31 is upregulated by METTL3 to promote pancreatic cancer progression via regulating SIRT2 ubiquitination and degradation

Kai Chen, Yue Wang, Xingna Dai, Jingjing Luo, Shangshang Hu, Zhihui Zhou, Jinglong Shi, Xueshan Pan, Tong Cao, Jun Xia, Yuyun Li, Zhiwei Wang, Jia Ma

Cell Death Dis. 2024 Jan; 15(1): 37. Published online 2024 Jan 12. doi: 10.1038/s41419-024-06425-y

PMCID:: PMC10786907

Abstract Article PDF–5.1M

Select item 101561753.

Systemwide disassembly and assembly of SCF ubiquitin ligase complexes

Kheewoong Baek, Daniel C. Scott, Lukas T. Henneberg, Moeko T. King, Matthias Mann, Brenda A. Schulman

Cell. 2023 Apr 27; 186(9): 1895–1911.e21. doi: 10.1016/j.cell.2023.02.035

Correction in:: Cell. 2023 May 25; 186(11): 2492.

PMCID:: PMC10156175

Abstract Article

Select item 101122814.

TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1

François Le Guerroué, Eric N Bunker, William M Rosencrans, Jack T Nguyen, Mohammed A Basar, Achim Werner, Tsui-Fen Chou, Chunxin Wang, Richard J Youle

Mol Cell. Author manuscript; available in PMC 2024 Mar 16.

Published in final edited form as: Mol Cell. 2023 Mar 16; 83(6): 927–941.e8. Published online 2023 Mar 9. doi: 10.1016/j.molcel.2023.02.023

PMCID:: PMC10112281

Abstract Article PDF–2.4M

Select item 99385685.

LincRNA ZNF529-AS1 inhibits hepatocellular carcinoma via FBXO31 and predicts the prognosis of hepatocellular carcinoma patients

Yang Ma, Wan-liang Sun, Shuo Shuo Ma, Guanru Zhao, Zhong Liu, Zheng Lu, Dengyong Zhang

BMC Bioinformatics. 2023; 24: 54. Published online 2023 Feb 17. doi: 10.1186/s12859-023-05189-0

PMCID:: PMC9938568

Abstract Article PDF–2.3M

Select item 94375636.

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk

Valentina Lukinović, Simone Hausmann, Gael S. Roth, Clement Oyeniran, Tanveer Ahmad, Ning Tsao, Joshua R. Brickner, Alexandre G. Casanova, Florent Chuffart, Ana Morales Benitez, Jessica Vayr, Rebecca Rodell, Marianne Tardif, Pascal W.T.C. Jansen, Yohann Couté, Michiel Vermeulen, Pierre Hainaut, Pawel K. Mazur, Nima Mosammaparast, Nicolas Reynoird

Cancer Discov. 2022 Sep 2; 12(9): 2158–2179. Published online 2022 Jul 12. doi: 10.1158/2159-8290.CD-21-0205

PMCID:: PMC9437563

Abstract Article PDF–9.5M

Select item 91485387.

Mutations disrupting neuritogenesis genes confer risk for cerebral palsy

Sheng Chih Jin, Sara A. Lewis, Somayeh Bakhtiari, Xue Zeng, Michael C. Sierant, Sheetal Shetty, Sandra M. Nordlie, Aureliane Elie, Mark A. Corbett, Bethany Y. Norton, Clare L. van Eyk, Shozeb Haider, Brandon S. Guida, Helen Magee, James Liu, Stephen Pastore, John B. Vincent, Janice Brunstrom-Hernandez, Antigone Papavasileiou, Michael C. Fahey, Jesia G. Berry, Kelly Harper, Chongchen Zhou, Junhui Zhang, Boyang Li, Jennifer Heim, Dani L. Webber, Mahalia S. B. Frank, Lei Xia, Yiran Xu, Dengna Zhu, Bohao Zhang, Amar H. Sheth, James R. Knight, Christopher Castaldi, Irina R. Tikhonova, Francesc López-Giráldez, Boris Keren, Sandra Whalen, Julien Buratti, Diane Doummar, Megan Cho, Kyle Retterer, Francisca Millan, Yangong Wang, Jeff L. Waugh, Lance Rodan, Julie S. Cohen, Ali Fatemi, Angela E. Lin, John P. Phillips, Timothy Feyma, Suzanna C. MacLennan, Spencer Vaughan, Kylie E. Crompton, Susan M. Reid, Dinah S. Reddihough, Qing Shang, Chao Gao, Iona Novak, Nadia Badawi, Yana A. Wilson, Sarah J. McIntyre, Shrikant M. Mane, Xiaoyang Wang, David J. Amor, Daniela C. Zarnescu, Qiongshi Lu, Qinghe Xing, Changlian Zhu, Kaya Bilguvar, Sergio Padilla-Lopez, Richard P. Lifton, Jozef Gecz, Alastair H. MacLennan, Michael C. Kruer

Nat Genet. Author manuscript; available in PMC 2022 May 29.

Published in final edited form as: Nat Genet. 2020 Oct; 52(10): 1046–1056. Published online 2020 Sep 28. doi: 10.1038/s41588-020-0695-1

Correction in:: Nat Genet. 2021 Jan 11

PMCID:: PMC9148538

Abstract Article PDF–3.8M

Select item 88421638.

Novel variants underlying autosomal recessive neurodevelopmental disorders with intellectual disability in Iranian consanguineous families

Mahdiyeh Moudi, Mohammad Yahya Vahidi Mehrjardi, Hossein Hozhabri, Zahra Metanat, Seyed Mehdi Kalantar, Mohsen Taheri, Nasrin Ghasemi, Mohammadreza Dehghani

J Clin Lab Anal. 2022 Feb; 36(2): e24241. Published online 2022 Jan 12. doi: 10.1002/jcla.24241

PMCID:: PMC8842163

Abstract Article PDF–1.0M

Select item 85772249.

Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis

Shanshan Duan, Loredana Moro, Rui Qu, Daniele Simoneschi, Hyunwoo Cho, Shaowen Jiang, Huiyong Zhao, Qing Chang, Elisa de Stanchina, Arnaldo A. Arbini, Michele Pagano

Cell Rep. Author manuscript; available in PMC 2021 Nov 9.

Published in final edited form as: Cell Rep. 2021 Oct 19; 37(3): 109870. doi: 10.1016/j.celrep.2021.109870

PMCID:: PMC8577224

Abstract Article PDF–1.3M

Select item 850719710.

FBXL20 promotes breast cancer malignancy by inhibiting apoptosis through degradation of PUMA and BAX

Rajesh Kumar Manne, Yashika Agrawal, Sunil K. Malonia, Shahid Banday, Sarathkumar Edachery, Asha Patel, Avinash Kumar, Praveenkumar Shetty, Manas Kumar Santra

J Biol Chem. 2021 Oct; 297(4): 101253. Published online 2021 Sep 26. doi: 10.1016/j.jbc.2021.101253

PMCID:: PMC8507197

Abstract Article PDF–4.0M

Select item 818499811.

Tumor-associated antigen Prame targets tumor suppressor p14/ARF for degradation as the receptor protein of CRL2^Prame complex

Wenjuan Zhang, Lihui Li, Lili Cai, Yupei Liang, Junfeng Xu, Yue Liu, Lisha Zhou, Chen Ding, Yanmei Zhang, Hu Zhao, Jun Qin, Zhimin Shao, Wenyi Wei, Lijun Jia

Cell Death Differ. 2021 Jun; 28(6): 1926–1940. Published online 2021 Jan 27. doi: 10.1038/s41418-020-00724-5

PMCID:: PMC8184998

Abstract Article PDF–4.0M

Select item 816503012.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 804589813.

Variant recurrence confirms the existence of a FBXO31‐related spastic‐dystonic cerebral palsy syndrome

Ivana Dzinovic, Matej Škorvánek, Petra Pavelekova, Chen Zhao, Boris Keren, Sandra Whalen, Somayeh Bakhtiari, Sheng Chih Jin, Michael C. Kruer, Robert Jech, Juliane Winkelmann, Michael Zech

Ann Clin Transl Neurol. 2021 Apr; 8(4): 951–955. Published online 2021 Mar 6. doi: 10.1002/acn3.51335

PMCID:: PMC8045898

Abstract Article PDF–248K

Select item 795279614.

MicroRNA‐210 targets FBXO31 to inhibit tumor progression and regulates the Wnt/β‐catenin signaling pathway and EMT in esophageal squamous cell carcinoma

Jing Meng, Chao Zhang, Tongquan Zhao, Guangwen Shi, Jingjing Zhao, Zhaoxia Lin

Thorac Cancer. 2021 Mar; 12(6): 932–940. Published online 2021 Feb 3. doi: 10.1111/1759-7714.13860

PMCID:: PMC7952796

Abstract Article PDF–5.0M

Select item 793327515.

Ubiquitin-specific protease 53 promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells

Dawoon Baek, Kwang Hwan Park, Kyoung-Mi Lee, Sujin Jung, Soyeong Joung, Jihyun Kim, Jin Woo Lee

Cell Death Dis. 2021 Mar; 12(3): 238. Published online 2021 Mar 4. doi: 10.1038/s41419-021-03517-x

PMCID:: PMC7933275

Abstract Article PDF–2.1M

Select item 679133316.

The tumor suppressor FBXO31 preserves genomic integrity by regulating DNA replication and segregation through precise control of cyclin A levels

Parul Dutta, Sehbanul Islam, Srinadh Choppara, Pallabi Sengupta, Anil Kumar, Avinash Kumar, Mohan R. Wani, Subhrangsu Chatterjee, Manas Kumar Santra

J Biol Chem. 2019 Oct 11; 294(41): 14879–14895. Published online 2019 Aug 14. doi: 10.1074/jbc.RA118.007055

PMCID:: PMC6791333

Abstract Article PDF–3.9M

Select item 632887417.

Prognostic values of F-box members in breast cancer: an online database analysis and literature review

Xiaochen Wang, Tao Zhang, Shizhen Zhang, Jinlan Shan

Biosci Rep. 2019 Jan 31; 39(1): BSR20180949. Prepublished online 2018 Oct 19. Published online 2019 Jan 3. doi: 10.1042/BSR20180949

PMCID:: PMC6328874

Abstract Article PDF–819K

Select item 582692618.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 579831719.

Degradation of FBXO31 by APC/C is regulated by AKT- and ATM-mediated phosphorylation

Srinadh Choppara, Sunil K. Malonia, Ganga Sankaran, Michael R. Green, Manas Kumar Santra

Proc Natl Acad Sci U S A. 2018 Jan 30; 115(5): 998–1003. Published online 2018 Jan 17. doi: 10.1073/pnas.1705954115

PMCID:: PMC5798317

Abstract Article PDF–1.3M

Select item 577703020.

Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCF^FBXO31 ubiquitin ligase

Yunfeng Li, Kai Jin, Eric Bunker, Xiaojuan Zhang, Xuemei Luo, Xuedong Liu, Bing Hao

Proc Natl Acad Sci U S A. 2018 Jan 9; 115(2): 319–324. Published online 2017 Dec 26. doi: 10.1073/pnas.1708677115

PMCID:: PMC5777030

Abstract Article PDF–1.2M

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