PMC Links for GEO Profiles (Select 70962324) - PMC

Links from GEO Profiles

Items: 1 to 20 of 37

<< First< Prev

Page of 2

Select item 109544541.

Histone lactylation-boosted ALKBH3 potentiates tumor progression and diminished promyelocytic leukemia protein nuclear condensates by m¹A demethylation of SP100A

Xiang Gu, Ai Zhuang, Jie Yu, Ludi Yang, Shengfang Ge, Jing Ruan, Renbing Jia, Xianqun Fan, Peiwei Chai

Nucleic Acids Res. 2024 Mar 21; 52(5): 2273–2289. Published online 2023 Dec 20. doi: 10.1093/nar/gkad1193

PMCID:: PMC10954454

Abstract Article PDF–4.2M

Select item 108169862.

The Role of Key Amino Acids of the Human Fe(II)/2OG-Dependent Dioxygenase ALKBH3 in Structural Dynamics and Repair Activity toward Methylated DNA

Lyubov Yu. Kanazhevskaya, Alexey A. Gorbunov, Maria V. Lukina, Denis A. Smyshliaev, Polina V. Zhdanova, Alexander A. Lomzov, Vladimir V. Koval

Int J Mol Sci. 2024 Jan; 25(2): 1145. Published online 2024 Jan 17. doi: 10.3390/ijms25021145

PMCID:: PMC10816986

Abstract Article PDF–6.3M

Select item 95751063.

LncRNA ALKBH3‐AS1 enhances ALKBH3 mRNA stability to promote hepatocellular carcinoma cell proliferation and invasion

Qiliang Lu, Hao Wang, Xiangxiang Lei, Qiancheng Ma, Jie Zhao, Wen Sun, Cheng Guo, Dongsheng Huang, Qiuran Xu

J Cell Mol Med. 2022 Oct; 26(20): 5292–5302. Published online 2022 Sep 13. doi: 10.1111/jcmm.17558

PMCID:: PMC9575106

Abstract Article PDF–10M

Select item 82542454.

ALKBH3 partner ASCC3 mediates P-body formation and selective clearance of MMS-induced 1-methyladenosine and 3-methylcytosine from mRNA

Kristian Lied Wollen, Lars Hagen, Cathrine B. Vågbø, Renana Rabe, Tobias S. Iveland, Per Arne Aas, Animesh Sharma, Bjørnar Sporsheim, Hilde O. Erlandsen, Vuk Palibrk, Magnar Bjørås, Davi M. Fonseca, Nima Mosammaparast, Geir Slupphaug

J Transl Med. 2021; 19: 287. Published online 2021 Jul 3. doi: 10.1186/s12967-021-02948-6

PMCID:: PMC8254245

Abstract Article PDF–2.8M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79181816.

Epigenetic loss of m¹A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen, conferring poor clinical outcome

Rosaura Esteve-Puig, Fina Climent, David Piñeyro, Eva Domingo-Domènech, Veronica Davalos, Maite Encuentra, Anna Rea, Nadia Espejo-Herrera, Marta Soler, Miguel Lopez, Vanessa Ortiz-Barahona, Gustavo Tapia, José-Tomás Navarro, Joan Cid, Lourdes Farré, Alberto Villanueva, Isolda Casanova, Ramon Mangues, Pablo Santamarina-Ojeda, Agustín F. Fernández, Mario F. Fraga, Miguel Angel Piris, Nitzan Kol, Chen Avrahami, Sharon Moshitch-Moshkovitz, Gideon Rechavi, Anna Sureda, Manel Esteller

Blood. 2021 Feb 18; 137(7): 994–999. Prepublished online 2020 Sep 11. doi: 10.1182/blood.2020005823

PMCID:: PMC7918181

Article

Select item 71455307.

Human RAD51 paralogue RAD51C fosters repair of alkylated DNA by interacting with the ALKBH3 demethylase

Monisha Mohan, Deepa Akula, Arun Dhillon, Arun Goyal, Roy Anindya

Nucleic Acids Res. 2019 Dec 16; 47(22): 11729–11745. Published online 2019 Oct 23. doi: 10.1093/nar/gkz938

PMCID:: PMC7145530

Abstract Article PDF–11M

Select item 67444178.

ALKBH overexpression in head and neck cancer: potential target for novel anticancer therapy

Tomaš Pilžys, Michał Marcinkowski, Wojciech Kukwa, Damian Garbicz, Małgorzata Dylewska, Karolina Ferenc, Adam Mieczkowski, Andrzej Kukwa, Ewa Migacz, Dominika Wołosz, Damian Mielecki, Arne Klungland, Jan Piwowarski, Jarosław Poznański, Elżbieta Grzesiuk

Sci Rep. 2019; 9: 13249. Published online 2019 Sep 13. doi: 10.1038/s41598-019-49550-x

PMCID:: PMC6744417

Abstract Article PDF–4.3M

Select item 67426469.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 658231710.

DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine in vitro

Ke Bian, Stefan A P Lenz, Qi Tang, Fangyi Chen, Rui Qi, Marco Jost, Catherine L Drennan, John M Essigmann, Stacey D Wetmore, Deyu Li

Nucleic Acids Res. 2019 Jun 20; 47(11): 5522–5529. Published online 2019 May 22. doi: 10.1093/nar/gkz395

PMCID:: PMC6582317

Abstract Article PDF–1.7M

Select item 644057711.

Isoform-specific GSK3A activity is negatively correlated with human sperm motility

M J Freitas, J V Silva, C Brothag, B Regadas-Correia, M Fardilha, S Vijayaraghavan

Mol Hum Reprod. 2019 Apr; 25(4): 171–183. Published online 2019 Mar 2. doi: 10.1093/molehr/gaz009

PMCID:: PMC6440577

Abstract Article PDF–1.0M

Select item 641183012.

Transfer RNA demethylase ALKBH3 promotes cancer progression via induction of tRNA-derived small RNAs

Zhuojia Chen, Meijie Qi, Bin Shen, Guanzheng Luo, Yingmin Wu, Jiexin Li, Zhike Lu, Zhong Zheng, Qing Dai, Hongsheng Wang

Nucleic Acids Res. 2019 Mar 18; 47(5): 2533–2545. Published online 2018 Dec 12. doi: 10.1093/nar/gky1250

PMCID:: PMC6411830

Abstract Article PDF–5.0M

Select item 631495713.

An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders

Siwei Chen, Robert Fragoza, Lambertus Klei, Yuan Liu, Jiebiao Wang, Kathryn Roeder, Bernie Devlin, Haiyuan Yu

Nat Genet. Author manuscript; available in PMC 2019 Jul 1.

Published in final edited form as: Nat Genet. 2018 Jul; 50(7): 1032–1040. Published online 2018 Jun 11. doi: 10.1038/s41588-018-0130-z

PMCID:: PMC6314957

Abstract Article PDF–1.3M

Select item 607772214.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 553161115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 549888516.

CpG promoter methylation of the ALKBH3 alkylation repair gene in breast cancer

Olafur Andri Stefansson, Stefan Hermanowicz, Jasper van der Horst, Holmfridur Hilmarsdottir, Zuzanna Staszczak, Jon Gunnlaugur Jonasson, Laufey Tryggvadottir, Thorkell Gudjonsson, Stefan Sigurdsson

BMC Cancer. 2017; 17: 469. Published online 2017 Jul 5. doi: 10.1186/s12885-017-3453-8

PMCID:: PMC5498885

Abstract Article PDF–1.8M

Select item 530422517.

AlkB homolog 3-mediated tRNA demethylation promotes protein synthesis in cancer cells

Yuko Ueda, Ikumi Ooshio, Yasuyuki Fusamae, Kaori Kitae, Megumi Kawaguchi, Kentaro Jingushi, Hiroaki Hase, Kazuo Harada, Kazumasa Hirata, Kazutake Tsujikawa

Sci Rep. 2017; 7: 42271. Published online 2017 Feb 13. doi: 10.1038/srep42271

PMCID:: PMC5304225

Abstract Article PDF–726K

Select item 526093918.

Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease

Felipe Roberti Teixeira, Suzanne J. Randle, Shachi P. Patel, Tycho E.T. Mevissen, Grasilda Zenkeviciute, Tie Koide, David Komander, Heike Laman

Biochem J. 2016 Oct 15; 473(20): 3563–3580. Prepublished online 2016 Aug 8. Published online 2016 Oct 11. doi: 10.1042/BCJ20160387

PMCID:: PMC5260939

Abstract Article PDF–1.1M

Select item 503813819.

Roles of Aag,Alkbh2, and Alkbh3 in the Repair of Carboxymethylated and Ethylated Thymidine Lesions

Changjun You, Pengcheng Wang, Stephanie L. Nay, Jianshuang Wang, Xiaoxia Dai, Timothy R. O’Connor, Yinsheng Wang

ACS Chem Biol. Author manuscript; available in PMC 2017 May 20.

Published in final edited form as: ACS Chem Biol. 2016 May 20; 11(5): 1332–1338. Published online 2016 Mar 4. doi: 10.1021/acschembio.6b00085

PMCID:: PMC5038138

Abstract Article PDF–1.1M

Select item 484201520.

The dynamic N¹-methyladenosine methylome in eukaryotic messenger RNA

Dan Dominissini, Sigrid Nachtergaele, Sharon Moshitch-Moshkovitz, Eyal Peer, Nitzan Kol, Moshe Shay Ben-Haim, Qing Dai, Ayelet Di Segni, Mali Salmon-Divon, Wesley C. Clark, Guanqun Zheng, Tao Pan, Oz Solomon, Eran Eyal, Vera Hershkovitz, Dali Han, Louis C. Doré, Ninette Amariglio, Gideon Rechavi, Chuan He

Nature. Author manuscript; available in PMC 2016 Apr 23.

Published in final edited form as: Nature. 2016 Feb 25; 530(7591): 441–446. Published online 2016 Feb 10. doi: 10.1038/nature16998

PMCID:: PMC4842015

Abstract Article PDF–4.7M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from GEO Profiles

Items: 1 to 20 of 37

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity