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Select item 93383131.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Abstract Article PDF–2.8M

Select item 71699832.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 67105293.

Prognostic significance of α‐ and β2‐adrenoceptor gene expression in breast cancer patients

Ezequiel Mariano Rivero, Leandro Marcelo Martinez, Carlos David Bruque, Lucia Gargiulo, Ariana Bruzzone, Isabel Alicia Lüthy

Br J Clin Pharmacol. 2019 Sep; 85(9): 2143–2154. Published online 2019 Jul 31. doi: 10.1111/bcp.14030

PMCID:: PMC6710529

Abstract Article PDF–2.2M

Select item 62845504.

Human Placenta Expresses α₂-Adrenergic Receptors and May Be Implicated in Pathogenesis of Preeclampsia and Fetal Growth Restriction

Hanaa K.B. Motawea, Maqsood A. Chotani, Mehboob Ali, William Ackerman, Guomao Zhao, Amany A.E. Ahmed, Catalin S. Buhimschi, Irina A. Buhimschi

Am J Pathol. 2018 Dec; 188(12): 2774–2785. doi: 10.1016/j.ajpath.2018.08.011

PMCID:: PMC6284550

Abstract Article

Select item 61434345.

α_2A- and α_2C-Adrenoceptors as Potential Targets for Dopamine and Dopamine Receptor Ligands

Marta Sánchez-Soto, Verònica Casadó-Anguera, Hideaki Yano, Brian Joseph Bender, Ning-Sheng Cai, Estefanía Moreno, Enric I Canela, Antoni Cortés, Jens Meiler, Vicent Casadó, Sergi Ferré

Mol Neurobiol. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: Mol Neurobiol. 2018 Nov; 55(11): 8438–8454. Published online 2018 Mar 18. doi: 10.1007/s12035-018-1004-1

PMCID:: PMC6143434

Abstract Article PDF–876K

Select item 56785816.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 45569377.

Genetic variation in alpha₂-adrenoreceptors and heart rate recovery after exercise

Utkarsh Kohli, André Diedrich, Prince J. Kannankeril, Mordechai Muszkat, Gbenga G. Sofowora, Maureen K. Hahn, Brett A. English, Randy D. Blakely, C. Michael Stein, Daniel Kurnik

Physiol Genomics. 2015 Sep; 47(9): 400–406. Published online 2015 Jun 9. doi: 10.1152/physiolgenomics.00124.2014

PMCID:: PMC4556937

Abstract Article

Select item 42980118.

Adrenergic receptor genotype influences heart failure severity and β-blocker response in children with dilated cardiomyopathy

Sushma Reddy, Alan Fung, Cedric Manlhiot, Elif Seda Selamet Tierney, Wendy K. Chung, Elizabeth Blume, Beth D. Kaufman, Elizabeth Goldmuntz, Steven Colan, Seema Mital

Pediatr Res. 2015 Feb; 77(2): 363–369. Prepublished online 2014 Nov 19. Published online 2014 Dec 10. doi: 10.1038/pr.2014.183

PMCID:: PMC4298011

Abstract Article PDF–714K

Select item 41285829.

In Silico Modeling of Human α_2C-Adrenoreceptor Interaction with Filamin-2

Marcin Pawlowski, Saras Saraswathi, Hanaa K. B. Motawea, Maqsood A. Chotani, Andrzej Kloczkowski

PLoS One. 2014; 9(8): e103099. Published online 2014 Aug 11. doi: 10.1371/journal.pone.0103099

PMCID:: PMC4128582

Abstract Article PDF–1.6M

Select item 403512210.

Common α2A and α2C adrenergic receptor polymorphisms do not affect plasma membrane trafficking

Carl M. Hurt, Matt W. Sorensen, Timothy Angelotti

Naunyn Schmiedebergs Arch Pharmacol. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: Naunyn Schmiedebergs Arch Pharmacol. 2014 Jun; 387(6): 569–579. Published online 2014 Mar 19. doi: 10.1007/s00210-014-0972-6

PMCID:: PMC4035122

Abstract Article PDF–3.3M

Select item 397531011.

The α2CDel322-325 adrenergic receptor polymorphism is not associated with heart failure due to idiopathic dilated cardiomyopathy in black Africans

J Du Preez, LO Matolweni, BM Mayosi, J Greenberg, P Mntla, AA Adeyemo

Cardiovasc J Afr. 2008 Feb; 19(1): 15–16.

PMCID:: PMC3975310

Abstract Article PDF–160K

Select item 397176712.

β₁- and α_2c-adrenoreceptor variants as predictors of clinical aspects of dilated cardiomyopathy in people of African ancestry

Angela J Woodiwiss, Danelle Badenhorst, Richard Brooksbank, Pinhas Sareli, Gavin R Norton, Karen Sliwa, Rafique Essop

Cardiovasc J Afr. 2008 Jul-Aug; 19(4): 188–193.

PMCID:: PMC3971767

Abstract Article PDF–251K

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 282920814.

Lack of effect of the α_2C-adrenoceptor Del322-325 polymorphism on inhibition of cyclic AMP production in HEK293 cells

MD Montgomery, DB Bylund

Br J Pharmacol. 2010 Feb; 159(4): 820–830. Published online 2010 Jan 28. doi: 10.1111/j.1476-5381.2009.00584.x

PMCID:: PMC2829208

Abstract Article PDF–309K

Select item 281511615.

Effects of variation in the human α_2A- and α_2C-adrenoceptor genes on cognitive tasks and pain perception

Utkarsh Kohli, Mordechai Muszkat, Gbenga G. Sofowora, Paul A. Harris, Eitan A. Friedman, William D. Dupont, Mika Scheinin, Alastair J.J. Wood, C. Michael Stein, Daniel Kurnik

Eur J Pain. Author manuscript; available in PMC 2011 Feb 1.

Published in final edited form as: Eur J Pain. 2010 Feb; 14(2): 154. Published online 2009 May 6. doi: 10.1016/j.ejpain.2009.04.003

PMCID:: PMC2815116

Abstract Article PDF–261K

Select item 277786616.

Genetical genomic determinants of alcohol consumption in rats and humans

Boris Tabakoff, Laura Saba, Morton Printz, Pam Flodman, Colin Hodgkinson, David Goldman, George Koob, Heather N Richardson, Katerina Kechris, Richard L Bell, Norbert Hübner, Matthias Heinig, Michal Pravenec, Jonathan Mangion, Lucie Legault, Maurice Dongier, Katherine M Conigrave, John B Whitfield, John Saunders, Bridget Grant, Paula L Hoffman, WHO/ISBRA Study on State and Trait Markers of Alcoholism

BMC Biol. 2009; 7: 70. Published online 2009 Oct 27. doi: 10.1186/1741-7007-7-70

PMCID:: PMC2777866

Abstract Article PDF–1.0M

Select item 275700917.

β₁-adrenoceptor genetic varians and ethnicity independently affect response to β-blockade

Daniel Kurnik, Chun Li, Gbenga G. Sofowora, Eitan A. Friedman, Mordechai Muszkat, Hong-Guang Xie, Paul A. Harris, Scott M. Williams, Usha B. Nair, Alastair J.J. Wood, C. Michael Stein

Pharmacogenet Genomics. Author manuscript; available in PMC 2009 Oct 5.

Published in final edited form as: Pharmacogenet Genomics. 2008 Oct; 18(10): 895–902. doi: 10.1097/FPC.0b013e328309733f

PMCID:: PMC2757009

Abstract Article PDF–465K

Select item 273968318.

The α_2C-adrenoceptor deletion322-325 variant and cold-induced vasoconstriction

Eitan A. Friedman, Paul A. Harris, Alastair J. J. Wood, C. Michael Stein, Daniel Kurnik

Clin Auton Res. Author manuscript; available in PMC 2010 Aug 1.

Published in final edited form as: Clin Auton Res. 2009 Aug; 19(4): 247–254. Published online 2009 May 15. doi: 10.1007/s10286-009-0014-5

PMCID:: PMC2739683

Abstract Article PDF–98K

Select item 273188519.

Genetic Ancestry, Social Classification, and Racial Inequalities in Blood Pressure in Southeastern Puerto Rico

Clarence C. Gravlee, Amy L. Non, Connie J. Mulligan

PLoS One. 2009; 4(9): e6821. Published online 2009 Sep 9. doi: 10.1371/journal.pone.0006821

PMCID:: PMC2731885

Abstract Article PDF–182K

Select item 269064120.

Pharmacogenetics of Low Dose Clonidine in Irritable Bowel Syndrome

Michael Camilleri, Irene Busciglio, Paula Carlson, Sanna McKinzie, Duane Burton, Kari Baxter, Michael Ryks, Alan R. Zinsmeister

Neurogastroenterol Motil. Author manuscript; available in PMC 2009 Oct 1.

Published in final edited form as: Neurogastroenterol Motil. 2009 Apr; 21(4): 399–410. doi: 10.1111/j.1365-2982.2009.01263.x

PMCID:: PMC2690641

Abstract Article PDF–151K

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