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Select item 110732171.

Reciprocal negative feedback regulation of ATF6α and PTEN promotes prostate cancer progression

Tingting Feng, Ru Zhao, Hanwen Zhang, Feifei Sun, Jing Hu, Meng Wang, Mei Qi, Ling Liu, Lin Gao, Yabo Xiao, Junhui Zhen, Weiwen Chen, Lin Wang, Bo Han

Cell Mol Life Sci. 2023 Oct; 80(10): 292. Published online 2023 Sep 16. doi: 10.1007/s00018-023-04940-3

PMCID:: PMC11073217

Abstract Article PDF–7.3M

Select item 107510502.

KCNH2_A561V Heterozygous Mutation Inhibits KCNH2 Protein Expression via The Activation of UPR Mediated by ATF6

Bangsheng CHEN, Lian TAN, Danqi CHEN, Xinghou WANG, Jiequan LIU, Xiaoyan HUANG, Ying WANG, Shuaishuai HUANG, Feiyan MAO, Jiangfang LIAN

Physiol Res. 2023 Oct; 72(5): 621–631. Published online 2023 Oct 31. doi: 10.33549/physiolres.935095

PMCID:: PMC10751050

Abstract Article PDF–1.6M

Select item 107391543.

Reinvestigation of Disulfide-bonded Oligomeric Forms of the Unfolded Protein Response Transducer ATF6

Hibiki Koba, Shengyu Jin, Nanami Imada, Tokiro Ishikawa, Satoshi Ninagawa, Tetsuya Okada, Tetsushi Sakuma, Takashi Yamamoto, Kazutoshi Mori

Cell Struct Funct. 2020; 45(1): 9–21. Published online 2019 Dec 19. doi: 10.1247/csf.19030

PMCID:: PMC10739154

Abstract Article PDF–1.3M

Select item 105304514.

Unfolded protein response factor ATF6 augments T helper cell responses and promotes mixed granulocytic airway inflammation

Dandan Wu, Xing Zhang, Kourtney M. Zimmerly, Ruoning Wang, Chunqing Wang, Russell Hunter, Xiang Wu, Matthew Campen, Meilian Liu, Xuexian O. Yang

Mucosal Immunol. Author manuscript; available in PMC 2023 Sep 27.

Published in final edited form as: Mucosal Immunol. 2023 Aug; 16(4): 499–512. Published online 2023 May 19. doi: 10.1016/j.mucimm.2023.05.007

PMCID:: PMC10530451

Abstract Article PDF–2.4M

Select item 105275595.

Targeting the ATF6-mediated ER stress response and autophagy blocks integrin-driven prostate cancer progression

Amanda J. Macke, Artem N. Pachikov, Taylor E. Divita, Mary E. Morris, Chad A. LaGrange, Melissa S. Holzapfel, Anatoly V. Kubyshkin, Evgeniya Y. Zyablitskaya, Tatiana P. Makalish, Sergey N. Eremenko, Haowen Qiu, Jean-Jack M. Riethoven, George P. Hemstreet, and Armen Petrosyan

Mol Cancer Res. Author manuscript; available in PMC 2024 Mar 1.

Published in final edited form as: Mol Cancer Res. 2023 Sep 1; 21(9): 958–974. doi: 10.1158/1541-7786.MCR-23-0108

PMCID:: PMC10527559

Abstract Article PDF–3.9M

Select item 103208706.

Protocadherin 20 maintains intestinal barrier function to protect against Crohn’s disease by targeting ATF6

Shanshan Huang, Zhuo Xie, Jing Han, Huiling Wang, Guang Yang, Manying Li, Gaoshi Zhou, Ying Wang, Lixuan Li, Li Li, Zhirong Zeng, Jun Yu, Minhu Chen, Shenghong Zhang

Genome Biol. 2023; 24: 159. Published online 2023 Jul 5. doi: 10.1186/s13059-023-02991-0

PMCID:: PMC10320870

Abstract Article PDF–5.9M

Select item 103042707.

ERVW-1 Activates ATF6-Mediated Unfolded Protein Response by Decreasing GANAB in Recent-Onset Schizophrenia

Xing Xue, Xiulin Wu, Lijuan Liu, Lianzhong Liu, Fan Zhu

Viruses. 2023 Jun; 15(6): 1298. Published online 2023 May 31. doi: 10.3390/v15061298

PMCID:: PMC10304270

Abstract Article PDF–6.3M

Select item 100117278.

Loss of ATF6α in a human carcinoma cell line is compensated not by its paralogue ATF6β but by sustained activation of the IRE1 and PERK arms for tumor growth in nude mice

Shengyu Jin, Byungseok Jin, Tokiro Ishikawa, Satoshi Ninagawa, Tetsuya Okada, Sho Koyasu, Hiroshi Harada, Kazutoshi Mori

Mol Biol Cell. 2023 Mar 1; 34(3): ar20. Published online 2023 Feb 21. doi: 10.1091/mbc.E22-07-0292

PMCID:: PMC10011727

Abstract Article PDF–11M

Select item 98129349.

ATF6-mediated signaling contributes to PARP Inhibitor Resistance in Ovarian Cancer

Alexandra McMellen, Tomomi M. Yamamoto, Lubna Qamar, Brooke E. Sanders, Lily L. Nguyen, Daniela Ortiz Chavez, Jaidev Bapat, Amber Berning, Miriam D. Post, Joshua Johnson, Kian Behbakht, Elmar Nurmemmedov, Edward B. Chuong, Benjamin G. Bitler

Mol Cancer Res. Author manuscript; available in PMC 2023 Jul 3.

Published in final edited form as: Mol Cancer Res. 2023 Jan 3; 21(1): 3–13. doi: 10.1158/1541-7786.MCR-22-0102

PMCID:: PMC9812934

Abstract Article PDF–1.5M

Select item 934857610.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 932466411.

Gremlin-1 Promotes Colorectal Cancer Cell Metastasis by Activating ATF6 and Inhibiting ATF4 Pathways

Ruohan Li, Huaixiang Zhou, Mingzhe Li, Qiuyan Mai, Zhang Fu, Youheng Jiang, Changxue Li, Yunfei Gao, Yunping Fan, Kaiming Wu, Clive Da Costa, Xia Sheng, Yulong He, Ningning Li

Cells. 2022 Jul; 11(14): 2136. Published online 2022 Jul 7. doi: 10.3390/cells11142136

PMCID:: PMC9324664

Abstract Article PDF–14M

Select item 930369512.

ATF6α promotes prostate cancer progression by enhancing PLA2G4A‐mediated arachidonic acid metabolism and protecting tumor cells against ferroptosis

Ru Zhao, Ye Lv, Tingting Feng, Ruojia Zhang, Luna Ge, Jihong Pan, Bo Han, Guanhua Song, Lin Wang

Prostate. 2022 Apr 1; 82(5): 617–629. Published online 2022 Jan 28. doi: 10.1002/pros.24308

PMCID:: PMC9303695

Abstract Article PDF–2.4M

Select item 923162313.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 911973614.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 903755415.

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy

Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell

Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116

PMCID:: PMC9037554

Abstract Article PDF–4.1M

Select item 882679916.

ATF6-Mediated Unfolded Protein Response Facilitates Adeno-associated Virus 2 (AAV2) Transduction by Releasing the Suppression of the AAV Receptor on Endoplasmic Reticulum Stress

Mengtian Cui, Qingfang Zhao, Jing Wang, Yang Si, Shan Cheng, Wei Ding

J Virol. 2022 Feb; 96(3): e01103-21. Prepublished online 2021 Dec 1. Published online 2022 Feb 9. doi: 10.1128/JVI.01103-21

PMCID:: PMC8826799

Abstract Article PDF–2.0M

Select item 848863217.

ATF6 is essential for human cone photoreceptor development

Heike Kroeger, Julia M. D. Grandjean, Wei-Chieh Jerry Chiang, Daphne D. Bindels, Rebecca Mastey, Jennifer Okalova, Amanda Nguyen, Evan T. Powers, Jeffery W. Kelly, Neil J. Grimsey, Michel Michaelides, Joseph Carroll, R. Luke Wiseman, Jonathan H. Lin

Proc Natl Acad Sci U S A. 2021 Sep 28; 118(39): e2103196118. Published online 2021 Sep 24. doi: 10.1073/pnas.2103196118

PMCID:: PMC8488632

Abstract Article PDF–2.6M

Select item 840959118.

Ubiquitination of ATF6 by disease-associated RNF186 promotes the innate receptor-induced unfolded protein response

Kishu Ranjan, Matija Hedl, Saloni Sinha, Xuchen Zhang, Clara Abraham

J Clin Invest. 2021 Sep 1; 131(17): e145472. Published online 2021 Sep 1. doi: 10.1172/JCI145472

PMCID:: PMC8409591

Abstract Article PDF–18M

Select item 823607819.

Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs

Katherine M. Almasy, Jonathan P. Davies, Lars Plate

Mol Cell Proteomics. 2021; 20: 100120. Published online 2021 Jun 27. doi: 10.1016/j.mcpro.2021.100120

PMCID:: PMC8236078

Abstract Article PDF–4.6M

Select item 817780020.

OTUB1 facilitates bladder cancer progression by stabilizing ATF6 in response to endoplasmic reticulum stress

Hui‐Hui Zhang, Chao Li, Jian‐Wei Ren, Lian Liu, Xue‐Hua Du, Jie Gao, Tao Liu, Shang‐Ze Li

Cancer Sci. 2021 Jun; 112(6): 2199–2209. Published online 2021 May 2. doi: 10.1111/cas.14876

PMCID:: PMC8177800

Abstract Article PDF–1.9M

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