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Items: 1 to 20 of 40

1.
GARP Correlates With Tumor-Infiltrating T-Cells and Predicts the Outcome of Gastric Cancer
Sutian Jiang, Yifan Zhang, Xiaojing Zhang, Bing Lu, Pingping Sun, Qianqian Wu, Xuzhong Ding, Jianfei Huang
Front Immunol. 2021; 12: 660397. Published online 2021 Aug 6. doi: 10.3389/fimmu.2021.660397
PMCID:
PMC8378229
AbstractArticlePDF–16M
2.
Dysregulated immunity in PID patients with low GARP expression on Tregs due to mutations in LRRC32
Peter Lehmkuhl, Magdalena Gentz, Andres Caballero Garcia de Otezya, Bodo Grimbacher, Hendrik Schulze-Koops, Alla Skapenko
Cell Mol Immunol. 2021 Jul; 18(7): 1677–1691. Published online 2021 May 31. doi: 10.1038/s41423-021-00701-z
PMCID:
PMC8245512
AbstractArticlePDF–4.5M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound GARP to activate LTGF-β
Alessandra Metelli, Bill X. Wu, Brian Riesenberg, Silvia Guglietta, John D. Huck, Catherine Mills, Anqi Li, Saleh Rachidi, Carsten Krieg, Mark P. Rubinstein, Daniel T. Gewirth, Shaoli Sun, Michael B. Lilly, Amy H. Wahlquist, David P. Carbone, Yiping Yang, Bei Liu, Zihai Li
Sci Transl Med. Author manuscript; available in PMC 2021 Jan 19.
Published in final edited form as: Sci Transl Med. 2020 Jan 8; 12(525): eaay4860. doi: 10.1126/scitranslmed.aay4860
PMCID:
PMC7814995
AbstractArticlePDF–2.7M
5.
Expression of Leucine-rich Repeat-containing Protein 32 Following Lymphocyte Stimulation in Patients with Non-IgE-mediated Gastrointestinal Food Allergies
Hisako Yagi, Koichiro Sato, Naoya Arakawa, Takaharu Inoue, Yutaka Nishida, Satoshi Yamada, Takashi Ishige, Yoshiyuki Yamada, Hirokazu Arakawa, Takumi Takizawa
Yale J Biol Med. 2020 Dec; 93(5): 645–655. Published online 2020 Dec 29.
PMCID:
PMC7757073
AbstractArticlePDF–606K
6.
GARP promotes the proliferation and therapeutic resistance of bone sarcoma cancer cells through the activation of TGF-β
Ana Belén Carrillo-Gálvez, Juan Esteban Quintero, René Rodríguez, Sofía T. Menéndez, M. Victoria González, Verónica Blanco-Lorenzo, Eva Allonca, Virgínea de Araújo Farias, Juan Elías González-Correa, Nadina Erill-Sagalés, Iñigo Martínez-Zubiaurre, Turid Hellevik, Sabina Sánchez-Hernández, Pilar Muñoz, Federico Zurita, Francisco Martín, Juan Carlos Rodríguez-Manzaneque, Per Anderson
Cell Death Dis. 2020 Nov; 11(11): 985. Published online 2020 Nov 17. doi: 10.1038/s41419-020-03197-z
PMCID:
PMC7673987
AbstractArticlePDF–6.8M
7.
The Parkinson’s Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network
Alexandra Beilina, Luis Bonet-Ponce, Ravindran Kumaran, Jennifer J. Kordich, Morié Ishida, Adamantios Mamais, Alice Kaganovich, Sara Saez-Atienzar, David C. Gershlick, Dorien A. Roosen, Laura Pellegrini, Vlad Malkov, Matthew J. Fell, Kirsten Harvey, Juan S. Bonifacino, Darren J. Moore, Mark R. Cookson
Cell Rep. Author manuscript; available in PMC 2020 Jun 25.
Published in final edited form as: Cell Rep. 2020 May 5; 31(5): 107614. doi: 10.1016/j.celrep.2020.107614
PMCID:
PMC7315779
AbstractArticlePDF–2.6M
8.
Homozygous stop-gain variant in LRRC32, encoding a TGFβ receptor, associated with cleft palate, proliferative retinopathy, and developmental delay
Tamar Harel, Ephrat Levy-Lahad, Muhannad Daana, Hadas Mechoulam, Smadar Horowitz-Cederboim, Michal Gur, Vardiella Meiner, Orly Elpeleg
Eur J Hum Genet. 2019 Aug; 27(8): 1315–1319. Published online 2019 Apr 11. doi: 10.1038/s41431-019-0380-y
PMCID:
PMC6777458
AbstractArticlePDF–639K
9.
GARP as an Immune Regulatory Molecule in the Tumor Microenvironment of Glioblastoma Multiforme
Niklas Zimmer, Ella Kim, Jonathan Schupp, Bettina Sprang, Petra Leukel, Fatemeh Khafaji, Florian Ringel, Clemens Sommer, Jochen Tuettenberg, Andrea Tuettenberg
Int J Mol Sci. 2019 Aug; 20(15): 3676. Published online 2019 Jul 26. doi: 10.3390/ijms20153676
PMCID:
PMC6695992
AbstractArticlePDF–21M
10.
Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins
Iain C. Macaulay, Marloes R. Tijssen, Daphne C. Thijssen-Timmer, Arief Gusnanto, Michael Steward, Philippa Burns, Cordelia F. Langford, Peter D. Ellis, Frank Dudbridge, Jaap-Jan Zwaginga, Nicholas A. Watkins, C. Ellen van der Schoot, Willem H. Ouwehand
Blood. Author manuscript; available in PMC 2019 Apr 26.
Published in final edited form as: Blood. 2007 Apr 15; 109(8): 3260–3269. Published online 2006 Dec 27. doi: 10.1182/blood-2006-07-036269
PMCID:
PMC6485507
AbstractArticlePDF–4.4M
11.
B lymphocytes confer immune tolerance via cell surface GARP-TGF-β complex
Caroline H. Wallace, Bill X. Wu, Mohammad Salem, Ephraim A. Ansa-Addo, Alessandra Metelli, Shaoli Sun, Gary Gilkeson, Mark J. Shlomchik, Bei Liu, Zihai Li
JCI Insight. 2018 Apr 5; 3(7): e99863. Published online 2018 Apr 5. doi: 10.1172/jci.insight.99863
PMCID:
PMC5928869
AbstractArticlePDF–2.7M
12.
Immunoregulatory functions and the therapeutic implications of GARP-TGF-β in inflammation and cancer
Alessandra Metelli, Mohammad Salem, Caroline H. Wallace, Bill X. Wu, Anqi Li, Xue Li, Zihai Li
J Hematol Oncol. 2018; 11: 24. Published online 2018 Feb 20. doi: 10.1186/s13045-018-0570-z
PMCID:
PMC5819195
AbstractArticlePDF–956K
13.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
14.
Surface Expression of TGF-β Docking Receptor GARP Promotes Oncogenesis and Immune Tolerance in Breast Cancer
Alessandra Metelli, Bill X Wu, Caroline W Fugle, Saleh Rachidi, Shaoli Sun, Yongliang Zhang, Jennifer Wu, Stephen Tomlinson, Philip Howe, Yi Yang, Elizabeth Garrett-Mayer, Bei Liu, Zihai Li
Cancer Res. Author manuscript; available in PMC 2017 Dec 15.
Published in final edited form as: Cancer Res. 2016 Dec 15; 76(24): 7106–7117. Published online 2016 Oct 20. doi: 10.1158/0008-5472.CAN-16-1456
PMCID:
PMC5504525
AbstractArticlePDF–1.8M
15.
Cutting Edge: Active TGF-β1 Released from GARP/TGF-β1 Complexes on the Surface of Stimulated Human B Lymphocytes Increases Class-Switch Recombination and Production of IgA
Olivier Dedobbeleer, Julie Stockis, Bas van der Woning, Pierre G. Coulie, Sophie Lucas
J Immunol. 2017 Jul 15; 199(2): 391–396. Published online 2017 Jun 12. doi: 10.4049/jimmunol.1601882
PMCID:
PMC5502319
AbstractArticlePDF–1.3M
16.
CD4+ CD25+ GARP+ regulatory T cells display a compromised suppressive function in patients with dilated cardiomyopathy
Yuzhen Wei, Kunwu Yu, Hui Wei, Xin Su, Ruirui Zhu, Huairui Shi, Haitao Sun, Quan Luo, Wenbin Xu, Junhui Xiao, Yucheng Zhong, Qiutang Zeng
Immunology. 2017 Jul; 151(3): 291–303. Published online 2017 Mar 29. doi: 10.1111/imm.12728
PMCID:
PMC5461097
AbstractArticlePDF–1.0M
17.
A key role of GARP in the immune suppressive tumor microenvironment
Susanne A. Hahn, Annemarie Neuhoff, Jenny Landsberg, Jonathan Schupp, Daniela Eberts, Petra Leukel, Matthias Bros, Martin Weilbaecher, Detlef Schuppan, Stephan Grabbe, Thomas Tueting, Volker Lennerz, Clemens Sommer, Helmut Jonuleit, Andrea Tuettenberg
Oncotarget. 2016 Jul 12; 7(28): 42996–43009. Published online 2016 May 27. doi: 10.18632/oncotarget.9598
PMCID:
PMC5190003
AbstractArticlePDF–4.9M
18.
GARP: a surface molecule of regulatory T cells that is involved in the regulatory function and TGF-β releasing
Liping Sun, Hao Jin, Hui Li
Oncotarget. 2016 Jul 5; 7(27): 42826–42836. Published online 2016 Apr 15. doi: 10.18632/oncotarget.8753
PMCID:
PMC5173174
AbstractArticlePDF–863K
19.
Combining FoxP3 and Helios with GARP/LAP markers can identify expanded Treg subsets in cancer patients
May Abd Al Samid, Belal Chaudhary, Yazan S. Khaled, Basil J. Ammori, Eyad Elkord
Oncotarget. 2016 Mar 22; 7(12): 14083–14094. Published online 2016 Feb 11. doi: 10.18632/oncotarget.7334
PMCID:
PMC4924699
AbstractArticlePDF–6.4M
20.
Meta-analysis of genome-wide association studies identifies 10 loci influencing allergic sensitization
Klaus Bønnelykke, Melanie C Matheson, Tune H Pers, Raquel Granell, David P Strachan, Alexessander Couto Alves, Allan Linneberg, John A Curtin, Nicole M Warrington, Marie Standl, Marjan Kerkhof, Ingileif Jonsdottir, Blazenka K Bukvic, Marika Kaakinen, Patrick Sleimann, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Katharina Schramm, Svetlana Baltic, Eskil Kreiner-Møller, Angela Simpson, Beate St Pourcain, Lachlan Coin, Jennie Hui, Eugene H Walters, Carla M T Tiesler, David L Duffy, Graham Jones, AAGC, Susan M Ring, Wendy L McArdle, Loren Price, Colin F Robertson, Juha Pekkanen, Clara S Tang, Elisabeth Thiering, Grant W Montgomery, Anna-Liisa Hartikainen, Shyamali C Dharmage, Lise L Husemoen, Christian Herder, John P Kemp, Paul Elliot, Alan James, Melanie Waldenberger, Michael J Abramson, Benjamin P Fairfax, Julian C Knight, Ramneek Gupta, Philip J Thompson, Patrick Holt, Peter Sly, Joel N Hirschhorn, Mario Blekic, Stephan Weidinger, Hakon Hakonarsson, Kari Stefansson, Joachim Heinrich, Dirkje S Postma, Adnan Custovic, Craig E Pennell, Marjo-Riitta Jarvelin, Gerard H Koppelman, Nicholas Timpson, Manuel A Ferreira, Hans Bisgaard, A John Henderson
Nat Genet. Author manuscript; available in PMC 2016 Jun 27.
Published in final edited form as: Nat Genet. 2013 Aug; 45(8): 902–906. Published online 2013 Jun 30. doi: 10.1038/ng.2694
PMCID:
PMC4922420
AbstractArticlePDF–937K

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