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Select item 81650301.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 67823302.

Molecular Basis for the Inactivation of Ca²⁺- and Voltage-Dependent BK Channels in Adrenal Chromaffin Cells and Rat Insulinoma Tumor Cells

Xiao-Ming Xia, Jiu Ping Ding, Christopher J. Lingle

J Neurosci. 1999 Jul 1; 19(13): 5255–5264. doi: 10.1523/JNEUROSCI.19-13-05255.1999

PMCID:: PMC6782330

Abstract Article PDF–377K

Select item 66729913.

BK Channels with β3a Subunits Generate Use-Dependent Slow Afterhyperpolarizing Currents by an Inactivation-Coupled Mechanism

Xu-Hui Zeng, G. Richard Benzinger, Xiao-Ming Xia, Christopher J. Lingle

J Neurosci. 2007 Apr 25; 27(17): 4707–4715. doi: 10.1523/JNEUROSCI.0758-07.2007

PMCID:: PMC6672991

Abstract Article PDF–1.8M

Select item 66009154.

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile

Karen Dendoncker, Steven Timmermans, Jolien Vandewalle, Melanie Eggermont, Joanna Lempiäinen, Evelien Van Hamme, Sylviane Dewaele, Sofie Vandevyver, Marlies Ballegeer, Jolien Souffriau, Lise Van Wyngene, Kelly Van Looveren, Tineke Vanderhaeghen, Rudi Beyaert, Karolien De Bosscher, Jorma J. Palvimo, Marc Van Montagu, Claude Libert

Proc Natl Acad Sci U S A. 2019 Jun 25; 116(26): 12942–12951. Published online 2019 Jun 10. doi: 10.1073/pnas.1821565116

Correction in:: Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15745.

PMCID:: PMC6600915

Abstract Article PDF–1.7M

Select item 43802095.

Two distinct effects of PIP₂ underlie auxiliary subunit-dependent modulation of Slo1 BK channels

Yutao Tian, Florian Ullrich, Rong Xu, Stefan H. Heinemann, Shangwei Hou, Toshinori Hoshi

J Gen Physiol. 2015 Apr; 145(4): 331–343. doi: 10.1085/jgp.201511363

PMCID:: PMC4380209

Abstract Article PDF–2.4M

Select item 39490556.

IFN-γ-mediated reduction of large-conductance, Ca²⁺-activated, voltage-dependent K⁺ (BK) channel activity in airway epithelial cells leads to mucociliary dysfunction

Dahis Manzanares, Maria Srinivasan, Samuel T. Salathe, Pedro Ivonnet, Nathalie Baumlin, John S. Dennis, Gregory E. Conner, Matthias Salathe

Am J Physiol Lung Cell Mol Physiol. 2014 Mar 1; 306(5): L453–L462. Published online 2014 Jan 10. doi: 10.1152/ajplung.00247.2013

PMCID:: PMC3949055

Abstract Article

Select item 37243377.

Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder

SE Bergen, CT O’Dushlaine, S Ripke, PH Lee, DM Ruderfer, S Akterin, JL Moran, KD Chambert, RE Handsaker, L Backlund, U Ösby, S McCarroll, M Landen, EM Scolnick, PKE Magnusson, P Lichtenstein, CM Hultman, SM Purcell, P Sklar, PF Sullivan

Mol Psychiatry. Author manuscript; available in PMC 2013 Jul 26.

Published in final edited form as: Mol Psychiatry. 2012 Sep; 17(9): 880–886. Published online 2012 Jun 12. doi: 10.1038/mp.2012.73

PMCID:: PMC3724337

Abstract Article PDF–318K

Select item 37201238.

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

Yi Lu, Veronique Vitart, Kathryn P Burdon, Chiea Chuen Khor, Yelena Bykhovskaya, Alireza Mirshahi, Alex W Hewitt, Demelza Koehn, Pirro G Hysi, Wishal D Ramdas, Tanja Zeller, Eranga N Vithana, Belinda K Cornes, Wan-Ting Tay, E Shyong Tai, Ching-Yu Cheng, Jianjun Liu, Jia-Nee Foo, Seang Mei Saw, Gudmar Thorleifsson, Kari Stefansson, David P Dimasi, Richard A Mills, Jenny Mountain, Wei Ang, René Hoehn, Virginie J M Verhoeven, Franz Grus, Roger Wolfs, Raphaële Castagne, Karl J Lackner, Henriët Springelkamp, Jian Yang, Fridbert Jonasson, Dexter Y L Leung, Li J Chen, Clement C Y Tham, Igor Rudan, Zoran Vatavuk, Caroline Hayward, Jane Gibson, Angela J Cree, Alex MacLeod, Sarah Ennis, Ozren Polasek, Harry Campbell, James F Wilson, Ananth C Viswanathan, Brian Fleck, Xiaohui Li, David Siscovick, Kent D Taylor, Jerome I Rotter, Seyhan Yazar, Megan Ulmer, Jun Li, Brian L Yaspan, Ayse B Ozel, Julia E Richards, Sayoko E Moroi, Jonathan L Haines, Jae H Kang, Louis R Pasquale, R Rand Allingham, Allison Ashley-Koch, NEIGHBOR Consortium, Paul Mitchell, Jie Jin Wang, Alan F Wright, Craig Pennell, Timothy D Spector, Terri L Young, Caroline C W Klaver, Nicholas G Martin, Grant W Montgomery, Michael G Anderson, Tin Aung, Colin E Willoughby, Janey L Wiggs, Chi P Pang, Unnur Thorsteinsdottir, Andrew J Lotery, Christopher J Hammond, Cornelia M van Duijn, Michael A Hauser, Yaron S Rabinowitz, Norbert Pfeiffer, David A Mackey, Jamie E Craig, Stuart Macgregor, Tien Y Wong

Nat Genet. Author manuscript; available in PMC 2014 Feb 1.

Published in final edited form as: Nat Genet. 2013 Feb; 45(2): 155–163. Published online 2013 Jan 6. doi: 10.1038/ng.2506

PMCID:: PMC3720123

Abstract Article PDF–1.2M

Select item 37183829.

The Interface between Membrane-Spanning and Cytosolic Domains in Ca²⁺-Dependent K⁺ Channels Is Involved in β Subunit Modulation of Gating

Xiaohui Sun, Jingyi Shi, Kelli Delaloye, Xiao Yang, Huanghe Yang, Guohui Zhang, Jianmin Cui

J Neurosci. 2013 Jul 3; 33(27): 11253–11261. doi: 10.1523/JNEUROSCI.0620-13.2013

PMCID:: PMC3718382

Abstract Article PDF–2.7M

Select item 319082610.

Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN

Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi

J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907

PMCID:: PMC3190826

Abstract Article PDF–5.7M

Select item 317805911.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 276239112.

Germline genomic variations associated with childhood acute lymphoblastic leukemia

Lisa R. Treviño, Wenjian Yang, Deborah French, Stephen Hunger, William L. Carroll, Meenakshi Devidas, Cheryl Willman, Geoffrey Neale, James Downing, Susana Raimondi, Ching-Hon Pui, William E. Evans, Mary V. Relling

Nat Genet. Author manuscript; available in PMC 2010 Mar 1.

Published in final edited form as: Nat Genet. 2009 Sep; 41(9): 1001–1005. Published online 2009 Aug 16. doi: 10.1038/ng.432

PMCID:: PMC2762391

Abstract Article PDF–359K

Select item 267822013.

β subunit-specific modulations of BK channel function by a mutation associated with epilepsy and dyskinesia

Urvi S Lee, Jianmin Cui

J Physiol. 2009 Apr 1; 587(Pt 7): 1481–1498. Published online 2009 Feb 9. doi: 10.1113/jphysiol.2009.169243

PMCID:: PMC2678220

Abstract Article PDF–955K

Select item 221732714.

Inactivation of BK Channels by the NH₂ Terminus of the β2 Auxiliary Subunit: An Essential Role of a Terminal Peptide Segment of Three Hydrophobic Residues

Xiao-Ming Xia, J.P. Ding, Christopher J. Lingle

J Gen Physiol. 2003 Feb; 121(2): 125–148. doi: 10.1085/jgp.20028667

PMCID:: PMC2217327

Abstract Article PDF–1.5M

Select item 215148815.

Structural Determinants for Functional Coupling Between the β and α Subunits in the Ca²⁺-activated K⁺ (BK) Channel

Patricio Orio, Yolima Torres, Patricio Rojas, Ingrid Carvacho, Maria L. Garcia, Ligia Toro, Miguel A. Valverde, Ramon Latorre

J Gen Physiol. 2006 Feb; 127(2): 191–204. doi: 10.1085/jgp.200509370

PMCID:: PMC2151488

Abstract Article PDF–3.5M

Select item 135612916.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406