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Items: 1 to 20 of 30

1.
Nlrp2 deletion ameliorates kidney damage in a mouse model of cystinosis
Marianna Nicoletta Rossi, Valentina Matteo, Francesca Diomedi-Camassei, Ester De Leo, Olivier Devuyst, Mohamed Lamkanfi, Ivan Caiello, Elena Loricchio, Francesco Bellomo, Anna Taranta, Francesco Emma, Fabrizio De Benedetti, Giusi Prencipe
Front Immunol. 2024; 15: 1373224. Published online 2024 Apr 3. doi: 10.3389/fimmu.2024.1373224
PMCID:
PMC11021658
AbstractArticlePDF–9.6M
2.
The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin
Dragomir B. Krastev, Shudong Li, Yilun Sun, Andrew J. Wicks, Gwendoline Hoslett, Daniel Weekes, Luned M. Badder, Eleanor G. Knight, Rebecca Marlow, Mercedes Calvo Pardo, Lu Yu, Tanaji T. Talele, Jiri Bartek, Jyoti S. Choudhary, Yves Pommier, Stephen J. Pettitt, Andrew N. J. Tutt, Kristijan Ramadan, Christopher J. Lord
Nat Cell Biol. 2022; 24(1): 62–73. Published online 2022 Jan 10. doi: 10.1038/s41556-021-00807-6
PMCID:
PMC8760077
AbstractArticlePDF–12M
3.
Somatic Mutation of NLRP Genes in Gastric and Colonic Cancers
Seong Won Moon, Hyun Ji Son, Ha Yoon Mo, Nam Jin Yoo, Sug Hyung Lee
Pathol Oncol Res. 2021; 27: 607385. Published online 2021 Apr 16. doi: 10.3389/pore.2021.607385
PMCID:
PMC8262223
AbstractArticlePDF–1.8M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
Targeting RICTOR sensitizes SMAD4-negative colon cancer to irinotecan
Chen Khuan Wong, Arthur William Lambert, Sait Ozturk, Panagiotis Papageorgis, Delia Lopez, Ning Shen, Zaina Sen, Hamid Mostafavi Abdolmaleky, Balázs Győrffy, Hui Feng, Sam Thiagalingam
Mol Cancer Res. Author manuscript; available in PMC 2020 Sep 1.
Published in final edited form as: Mol Cancer Res. 2020 Mar; 18(3): 414–423. Published online 2020 Jan 13. doi: 10.1158/1541-7786.MCR-19-0525
PMCID:
PMC7115128
AbstractArticlePDF–1.6M
6.
MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1
Hui Li, Chia-Wei Li, Xiaoqiang Li, Qingqing Ding, Lei Guo, Shuang Liu, Chunxiao Liu, Chien-Chen Lai, Jung-Mao Hsu, Qiongzhu Dong, Weiya Xia, Jennifer L. Hsu, Hirohito Yamaguchi, Yi Du, Yun-Ju Lai, Xian Sun, Paul B. Koller, Qinghai Ye, Mien-Chie Hung
Gastroenterology. Author manuscript; available in PMC 2020 May 1.
Published in final edited form as: Gastroenterology. 2019 May; 156(6): 1849–1861.e13. Published online 2019 Jan 31. doi: 10.1053/j.gastro.2019.01.252
PMCID:
PMC6904924
AbstractArticlePDF–2.0M
7.
Downregulation of NLRP2 inhibits HUVEC viability by inhibiting the MAPK signaling pathway
Xiaolu Zhang, Xinlei Lu, Limei Yu, Yufeng Gu, Fuzheng Qu
Mol Med Rep. 2019 Jan; 19(1): 85–92. Published online 2018 Nov 5. doi: 10.3892/mmr.2018.9625
PMCID:
PMC6297776
AbstractArticlePDF–2.4M
8.
Characterization of multi-locus imprinting disturbances and underlying genetic defects in patients with chromosome 11p15.5 related imprinting disorders
L. Fontana, M. F. Bedeschi, S. Maitz, A. Cereda, C. Faré, S. Motta, A. Seresini, P. D’Ursi, A. Orro, V. Pecile, M. Calvello, A. Selicorni, F. Lalatta, D. Milani, S. M. Sirchia, M. Miozzo, S. Tabano
Epigenetics. 2018; 13(9): 897–909. Published online 2018 Oct 21. doi: 10.1080/15592294.2018.1514230
PMCID:
PMC6284780
AbstractArticlePDF–2.5M
9.
Maternal variants in NLRP and other maternal effect proteins are associated with multilocus imprinting disturbance in offspring
Matthias Begemann, Faisal I Rezwan, Jasmin Beygo, Louise E Docherty, Julia Kolarova, Christopher Schroeder, Karin Buiting, Kamal Chokkalingam, Franziska Degenhardt, Emma L Wakeling, Stephanie Kleinle, Daniela González Fassrainer, Barbara Oehl-Jaschkowitz, Claire L S Turner, Michal Patalan, Maria Gizewska, Gerhard Binder, Can Thi Bich Ngoc, Vu Chi Dung, Sarju G Mehta, Gareth Baynam, Julian P Hamilton-Shield, Sara Aljareh, Oluwakemi Lokulo-Sodipe, Rachel Horton, Reiner Siebert, Miriam Elbracht, Isabel Karen Temple, Thomas Eggermann, Deborah J G Mackay
J Med Genet. 2018 Jul; 55(7): 497–504. Published online 2018 Mar 24. doi: 10.1136/jmedgenet-2017-105190
PMCID:
PMC6047157
AbstractArticlePDF–354K
10.
Early onset of inflammation during ontogeny of bipolar disorder: the NLRP2 inflammasome gene distinctly differentiates between patients and healthy controls in the transition between iPS cell and neural stem cell stages
D Vizlin-Hodzic, Q Zhai, S Illes, K Södersten, K Truvé, T Z Parris, P K Sobhan, S Salmela, S T Kosalai, C Kanduri, J Strandberg, H Seth, T O Bontell, E Hanse, H Ågren, K Funa
Transl Psychiatry. 2017 Jan; 7(1): e1010. Published online 2017 Jan 24. doi: 10.1038/tp.2016.284
PMCID:
PMC5545741
AbstractArticlePDF–1.8M
11.
Nuclear localization of Beclin 1 promotes radiation-induced DNA damage repair independent of autophagy
Fei Xu, Yixuan Fang, Lili Yan, Lan Xu, Suping Zhang, Yan Cao, Li Xu, Xiaoying Zhang, Jialing Xie, Gaoyue Jiang, Chaorong Ge, Ni An, Daohong Zhou, Na Yuan, Jianrong Wang
Sci Rep. 2017; 7: 45385. Published online 2017 Mar 27. doi: 10.1038/srep45385
Correction in:
Sci Rep. 2019; 9: 5594.
PMCID:
PMC5366945
AbstractArticlePDF–2.1M
12.
Panorama of ancient metazoan macromolecular complexes
Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili
Nature. Author manuscript; available in PMC 2016 Sep 26.
Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877
PMCID:
PMC5036527
AbstractArticlePDF–4.7M
13.
E-cadherin interactome complexity and robustness resolved by quantitative proteomics
Zhenhuan Guo, Lisa J Neilson, Hang Zhong, Paul S Murray, Megha Vaman Rao, Sara Zanivan, Ronen Zaidel-Bar
Sci Signal. Author manuscript; available in PMC 2016 Aug 3.
Published in final edited form as: Sci Signal. 2014 Dec 2; 7(354): rs7. Published online 2014 Dec 2. doi: 10.1126/scisignal.2005473
PMCID:
PMC4972397
AbstractArticlePDF–3.1M
14.
The Q705K and F359L Single-Nucleotide Polymorphisms of NOD-Like Receptor Signaling Pathway: Association with Chronic Pancreatitis, Pancreatic Cancer, and Periodontitis
Andrzej Miskiewicz, Grzegorz Szparecki, Marek Durlik, Grażyna Rydzewska, Ireneusz Ziobrowski, Renata Górska
Arch Immunol Ther Exp (Warsz) 2015; 63(6): 485–494. Published online 2015 Aug 8. doi: 10.1007/s00005-015-0355-9
PMCID:
PMC4633443
AbstractArticlePDF–873K
15.
The CLRX.1/NOD24 (NLRP2P) Pseudogene Codes a Functional Negative Regulator of NF-κB, Pyrin-only Protein 4 (POP4)
Kristen A. Porter, Ellen B. Duffy, Patricia Nyland, Maninjay K. Atianand, Hamayun J. Sharifi, Jonathan A. Harton
Genes Immun. Author manuscript; available in PMC 2015 Jan 30.
Published in final edited form as: Genes Immun. 2014 Sep; 15(6): 392–403. Published online 2014 May 29. doi: 10.1038/gene.2014.30
PMCID:
PMC4311403
AbstractArticlePDF–2.5M
16.
No evidence for mutations in NLRP7, NLRP2 or KHDC3L in women with unexplained recurrent pregnancy loss or infertility
L. Aghajanova, S. Mahadevan, S. Altmäe, A. Stavreus-Evers, L. Regan, N. Sebire, P. Dixon, R.A. Fisher, I.B. Van den Veyver
Hum Reprod. 2015 Jan; 30(1): 232–238. Published online 2014 Nov 5. doi: 10.1093/humrep/deu296
PMCID:
PMC4262469
AbstractArticlePDF–172K
17.
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins, Stephan Ripke, Rinse K Weersma, Richard H Duerr, Dermot P McGovern, Ken Y Hui, James C Lee, L Philip Schumm, Yashoda Sharma, Carl A Anderson, Jonah Essers, Mitja Mitrovic, Kaida Ning, Isabelle Cleynen, Emilie Theatre, Sarah L Spain, Soumya Raychaudhuri, Philippe Goyette, Zhi Wei, Clara Abraham, Jean-Paul Achkar, Tariq Ahmad, Leila Amininejad, Ashwin N Ananthakrishnan, Vibeke Andersen, Jane M Andrews, Leonard Baidoo, Tobias Balschun, Peter A Bampton, Alain Bitton, Gabrielle Boucher, Stephan Brand, Carsten Büning, Ariella Cohain, Sven Cichon, Mauro D’Amato, Dirk De Jong, Kathy L Devaney, Marla Dubinsky, Cathryn Edwards, David Ellinghaus, Lynnette R Ferguson, Denis Franchimont, Karin Fransen, Richard Gearry, Michel Georges, Christian Gieger, Jürgen Glas, Talin Haritunians, Ailsa Hart, Chris Hawkey, Matija Hedl, Xinli Hu, Tom H Karlsen, Limas Kupcinskas, Subra Kugathasan, Anna Latiano, Debby Laukens, Ian C Lawrance, Charlie W Lees, Edouard Louis, Gillian Mahy, John Mansfield, Angharad R Morgan, Craig Mowat, William Newman, Orazio Palmieri, Cyriel Y Ponsioen, Uros Potocnik, Natalie J Prescott, Miguel Regueiro, Jerome I Rotter, Richard K Russell, Jeremy D Sanderson, Miquel Sans, Jack Satsangi, Stefan Schreiber, Lisa A Simms, Jurgita Sventoraityte, Stephan R Targan, Kent D Taylor, Mark Tremelling, Hein W Verspaget, Martine De Vos, Cisca Wijmenga, David C Wilson, Juliane Winkelmann, Ramnik J Xavier, Sebastian Zeissig, Bin Zhang, Clarence K Zhang, Hongyu Zhao, The International IBD Genetics Consortium, Mark S Silverberg, Vito Annese, Hakon Hakonarson, Steven R Brant, Graham Radford-Smith, Christopher G Mathew, John D Rioux, Eric E Schadt, Mark J Daly, Andre Franke, Miles Parkes, Severine Vermeire, Jeffrey C Barrett, Judy H Cho
Nature. Author manuscript; available in PMC 2013 May 1.
Published in final edited form as: Nature. 2012 Nov 1; 491(7422): 119–124. doi: 10.1038/nature11582
PMCID:
PMC3491803
AbstractArticlePDF–706K
18.
Uncoupling of Pyrin-only Protein 2 (POP2)-mediated Dual Regulation of NF-κB and the Inflammasome
Maninjay K. Atianand, Jonathan A. Harton
J Biol Chem. 2011 Nov 25; 286(47): 40536–40547. Published online 2011 Oct 5. doi: 10.1074/jbc.M111.274290
PMCID:
PMC3220484
AbstractArticlePDF–1.0M
19.
Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN
Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi
J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907
PMCID:
PMC3190826
AbstractArticlePDF–5.7M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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