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Select item 101516151.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 83641812.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80787284.

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics

Alexandra Naba, Oliver M. T. Pearce, Amanda Del Rosario, Duanduan Ma, Huiming Ding, Vinothini Rajeeve, Pedro R. Cutillas, Frances R. Balkwill, Richard O. Hynes

J Proteome Res. Author manuscript; available in PMC 2021 Apr 27.

Published in final edited form as: J Proteome Res. 2017 Aug 4; 16(8): 3083–3091. Published online 2017 Jul 19. doi: 10.1021/acs.jproteome.7b00191

PMCID:: PMC8078728

Abstract Article PDF–2.1M

Select item 76458635.

N‐Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS‐CoV‐2 Main Protease

Tomas Koudelka, Juliane Boger, Alessandra Henkel, Robert Schönherr, Stefanie Krantz, Sabine Fuchs, Estefanía Rodríguez, Lars Redecke, Andreas Tholey

Proteomics. 2021 Jan; 21(2): 2000246. Published online 2020 Nov 17. doi: 10.1002/pmic.202000246

PMCID:: PMC7645863

Abstract Article PDF–497K

Select item 61666826.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 55316117.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 51755828.

The Functions of the A1A2A3 Domains in Von Willebrand Factor Include Multimerin 1 Binding

D’Andra N. Parker, Subia Tasneem, Richard W. Farndale, Dominique Bihan, J. Evan Sadler, Silvie Sebastian, Philip G. De Groot, Catherine P. M. Hayward

Thromb Haemost. 2016 Jul 5; 116(1): 87–95. Published online 2016 Apr 7. doi: 10.1160/TH15-09-0700

PMCID:: PMC5175582

Abstract Article PDF–1.6M

Select item 47427429.

Extracellular Fibrinogen-binding Protein (Efb) from Staphylococcus aureus Inhibits the Formation of Platelet-Leukocyte Complexes

Mareike G. Posner, Abhishek Upadhyay, Aisha Alsheikh Abubaker, Tiago M. Fortunato, Dina Vara, Ilaria Canobbio, Stefan Bagby, Giordano Pula

J Biol Chem. 2016 Feb 5; 291(6): 2764–2776. Published online 2015 Dec 1. doi: 10.1074/jbc.M115.678359

PMCID:: PMC4742742

Abstract Article PDF–2.8M

Select item 463004110.

Circulating Anti-Elastin Antibody Levels and Arterial Disease Characteristics: Associations with Arterial Stiffness and Atherosclerosis

Seung-Hyun Lee, Kihyuk Shin, Sungha Park, Seok-Min Kang, Donghoon Choi, Seung-Hyo Lee, Sang-Hak Lee

Yonsei Med J. 2015 Nov 1; 56(6): 1545–1551. Published online 2015 Sep 25. doi: 10.3349/ymj.2015.56.6.1545

Correction in:: Yonsei Med J. 2016 Jan 1; 57(1): 275.

PMCID:: PMC4630041

Abstract Article PDF–699K

Select item 461721111.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 450623712.

Multimerin-1 (MMRN1) as Novel Adverse Marker in Pediatric Acute Myeloid Leukemia: A Report from the Children’s Oncology Group

George S. Laszlo, Todd A. Alonzo, Chelsea J. Gudgeon, Kimberly H. Harrington, Robert B. Gerbing, Yi-Cheng Wang, Rhonda E. Ries, Susana C. Raimondi, Betsy A. Hirsch, Alan S. Gamis, Soheil Meshinchi, Roland B. Walter

Clin Cancer Res. Author manuscript; available in PMC 2016 Jul 15.

Published in final edited form as: Clin Cancer Res. 2015 Jul 15; 21(14): 3187–3195. Published online 2015 Mar 30. doi: 10.1158/1078-0432.CCR-14-2684

PMCID:: PMC4506237

Abstract Article PDF–905K

Select item 386171013.

SILAC-Based Proteomics of Human Primary Endothelial Cell Morphogenesis Unveils Tumor Angiogenic Markers

Sara Zanivan, Federica Maione, Marco Y. Hein, Juan Ramon Hernández-Fernaud, Pawel Ostasiewicz, Enrico Giraudo, Matthias Mann

Mol Cell Proteomics. 2013 Dec; 12(12): 3599–3611. Published online 2013 Aug 26. doi: 10.1074/mcp.M113.031344

PMCID:: PMC3861710

Abstract Article PDF–2.3M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 307446515.

Replication of GWAS associations for GAK and MAPT in Parkinson’s disease

SHANNON L. RHODES, JANET S. SINSHEIMER, YVETTE BORDELON, JEFF M. BRONSTEIN, BEATE RITZ

Ann Hum Genet. Author manuscript; available in PMC 2012 Mar 1.

Published in final edited form as: Ann Hum Genet. 2011 Mar; 75(2): 195–200. Published online 2010 Nov 8. doi: 10.1111/j.1469-1809.2010.00616.x

PMCID:: PMC3074465

Abstract Article PDF–307K

Select item 278772516.

Genome-Wide Association Study reveals genetic risk underlying Parkinson’s disease

Javier Simon-Sanchez, Claudia Schulte, Jose M Bras, Manu Sharma, J Raphael Gibbs, Daniela Berg, Coro Paisan-Ruiz, Peter Lichtner, Sonja W Scholz, Dena G Hernandez, Rejko Kruger, Monica Federoff, Christine Klein, Alison Goate, Joel Perlmutter, Michael Bonin, Michael A Nalls, Thomas Illig, Christian Gieger, Henry Houlden, Michael Steffens, Michael S. Okun, Mark Cookson, Kelly D Foote, Hubert H Fernandez, Bryan J. Traynor, Stefan Schreiber, Sampath Arepalli, Ryan Zonozi, Katrina Gwinn, Marcel van der Brug, Grisel Lopez, Stephen J Chanock, Arthur Schatzkin, Yikyung Park, Albert Hollenbeck, Jianjun Gao, Xuemei Huang, Nick W Wood, Delia Lorenz, Gunther Deuschl, Honglei Chen, Olaf Riess, John A Hardy, Andrew B Singleton, Thomas Gasser

Nat Genet. Author manuscript; available in PMC 2010 Jun 1.

Published in final edited form as: Nat Genet. 2009 Dec; 41(12): 1308–1312. Published online 2009 Nov 15. doi: 10.1038/ng.487