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Items: 1 to 20 of 30

1.
Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome
Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584
PMCID:
PMC8769072
AbstractArticlePDF–2.9M
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
A constricted opening in Kir channels does not impede potassium conduction
Katrina A. Black, Sitong He, Ruitao Jin, David M. Miller, Jani R. Bolla, Oliver B. Clarke, Paul Johnson, Monique Windley, Christopher J. Burns, Adam P. Hill, Derek Laver, Carol V. Robinson, Brian J. Smith, Jacqueline M. Gulbis
Nat Commun. 2020; 11: 3024. Published online 2020 Jun 15. doi: 10.1038/s41467-020-16842-0
PMCID:
PMC7295778
AbstractArticlePDF–2.5M
4.
GIRK1 triggers multiple cancer-related pathways in the benign mammary epithelial cell line MCF10A
Gebhard Schratter, Susanne Scheruebel, Sonja Langthaler, Katja Ester, Brigitte Pelzmann, Nassim Ghaffari-Tabrizi-Wizsy, Simin Rezania, Astrid Gorischek, Dieter Platzer, Klaus Zorn-Pauly, Helmut Ahammer, Andreas Prokesch, Stefanie Stanzer, Trevor T. J. Devaney, Kurt Schmidt, Stephan W. Jahn, Ruth Prassl, Thomas Bauernhofer, Wolfgang Schreibmayer
Sci Rep. 2019; 9: 19277. Published online 2019 Dec 17. doi: 10.1038/s41598-019-55683-w
PMCID:
PMC6917815
AbstractArticlePDF–5.3M
5.
Heteromultimerization of G-Protein-Gated Inwardly Rectifying K+ Channel Proteins GIRK1 and GIRK2 and Their Altered Expression in weaver Brain
Y. Joyce Liao, Yuh Nung Jan, Lily Yeh Jan
J Neurosci. 1996 Nov 15; 16(22): 7137–7150. doi: 10.1523/JNEUROSCI.16-22-07137.1996
PMCID:
PMC6578936
AbstractArticlePDF–2.0M
6.
Gi/o-coupled muscarinic receptors co-localize with GIRK channel for efficient channel activation
Michihiro Tateyama, Yoshihiro Kubo
PLoS One. 2018; 13(9): e0204447. Published online 2018 Sep 21. doi: 10.1371/journal.pone.0204447
PMCID:
PMC6150519
AbstractArticlePDF–9.5M
7.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
8.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
9.
KCNJ3 is a new independent prognostic marker for estrogen receptor positive breast cancer patients
Sarah Kammerer, Armin Sokolowski, Hubert Hackl, Dieter Platzer, Stephan Wenzel Jahn, Amin El-Heliebi, Daniela Schwarzenbacher, Verena Stiegelbauer, Martin Pichler, Simin Rezania, Heidelinde Fiegl, Florentia Peintinger, Peter Regitnig, Gerald Hoefler, Wolfgang Schreibmayer, Thomas Bauernhofer
Oncotarget. 2016 Dec 20; 7(51): 84705–84717. Published online 2016 Nov 8. doi: 10.18632/oncotarget.13224
PMCID:
PMC5356693
AbstractArticlePDF–7.1M
10.
Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner
S. Rezania, S. Kammerer, C. Li, B. Steinecker-Frohnwieser, A. Gorischek, T. T. J. DeVaney, S. Verheyen, C. A. Passegger, N. Ghaffari Tabrizi-Wizsy, H. Hackl, D. Platzer, A. H. Zarnani, E. Malle, S. W. Jahn, T. Bauernhofer, W. Schreibmayer
BMC Cancer. 2016; 16: 628. Published online 2016 Aug 12. doi: 10.1186/s12885-016-2664-8
PMCID:
PMC4983040
AbstractArticlePDF–2.2M
11.
The GIRK1 subunit potentiates G protein activation of cardiac GIRK1/4 hetero-tetramers
Kouki K Touhara, Weiwei Wang, Roderick MacKinnon
eLife. 2016; 5: e15750. Published online 2016 Apr 13. doi: 10.7554/eLife.15750
PMCID:
PMC4866825
AbstractArticlePDF–1.3M
12.
GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region
Don L. Armstrong, Raphael Zidovetzki, Marta E Alarcón-Riquelme, Betty P Tsao, Lindsey A Criswell, Robert P Kimberly, John B Harley, Kathy L Sivils, Timothy J Vyse, Patrick M. Gaffney, Carl D Langefeld, Chaim O. Jacob
Genes Immun. Author manuscript; available in PMC 2015 Mar 1.
Published in final edited form as: Genes Immun. 2014 Sep; 15(6): 347–354. Published online 2014 May 29. doi: 10.1038/gene.2014.23
PMCID:
PMC4156543
AbstractArticlePDF–1.5M
13.
VARIATIONS IN POTASSIUM CHANNEL GENES ARE ASSOCIATED WITH BREAST PAIN IN WOMEN PRIOR TO BREAST CANCER SURGERY
Dale J. Langford, Claudia West, Charles Elboim, Bruce A. Cooper, Gary Abrams, Steven M. Paul, Brian L. Schmidt, Jon D. Levine, John D. Merriman, Anand Dhruva, John Neuhaus, Heather Leutwyler, Christina Baggott, Carmen Ward Sullivan, Bradley E. Aouizerat, Christine Miaskowski
J Neurogenet. Author manuscript; available in PMC 2015 Mar 1.
Published in final edited form as: J Neurogenet. 2014 Mar-Jun; 28(0): 122–135. Published online 2014 Jan 7. doi: 10.3109/01677063.2013.856430
PMCID:
PMC4035357
AbstractArticlePDF–453K
14.
Rare independent mutations in renal salt handling genes contribute to blood pressure variation
Weizhen Ji, Jia Nee Foo, Brian J. O'Roak, Hongyu Zhao, Martin G. Larson, David B. Simon, Christopher Newton-Cheh, Matthew W. State, Daniel Levy, Richard P. Lifton
Nat Genet. Author manuscript; available in PMC 2013 Sep 8.
Published in final edited form as: Nat Genet. 2008 May; 40(5): 592–599. Published online 2008 Apr 6. doi: 10.1038/ng.118
PMCID:
PMC3766631
AbstractArticlePDF–1.5M
15.
Transcriptional Expression of Voltage-gated Na+ and Voltage-independent K+ Channels in the Developing Rat Superficial Dorsal Horn
Meredith L. Blankenship, Dennis E. Coyle, Mark L. Baccei
Neuroscience. Author manuscript; available in PMC 2014 Feb 12.
Published in final edited form as: Neuroscience. 2013 Feb 12; 231: 305–314. Published online 2012 Dec 7. doi: 10.1016/j.neuroscience.2012.11.053
PMCID:
PMC3563431
AbstractArticlePDF–823K
16.
Conformational Dynamics of Kir3.1/Kir3.2 Channel Activation Via δ-Opioid Receptors
Melissa Richard-Lalonde, Karim Nagi, Nicolas Audet, Rory Sleno, Mohammad Amraei, Mireille Hogue, Gianfranco Balboni, Peter W. Schiller, Michel Bouvier, Terence E. Hébert, Graciela Pineyro
Mol Pharmacol. 2013 Feb; 83(2): 416–428. Published online 2013 Feb. doi: 10.1124/mol.112.081950
PMCID:
PMC3558812
AbstractArticlePDF–1.5M
17.
Association study of the KCNJ3 gene as a susceptibility candidate for schizophrenia in the Chinese population
Kazuo Yamada, Yoshimi Iwayama, Tomoko Toyota, Tetsuo Ohnishi, Hisako Ohba, Motoko Maekawa, Takeo Yoshikawa
Hum Genet. 2012; 131(3): 443–451. Published online 2011 Sep 17. doi: 10.1007/s00439-011-1089-3
PMCID:
PMC3277701
AbstractArticlePDF–366K
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Identification of a Kir3.4 Mutation in Congenital Long QT Syndrome
Yanzong Yang, Yiqing Yang, Bo Liang, Jinqiu Liu, Jun Li, Morten Grunnet, Søren-Peter Olesen, Hanne B. Rasmussen, Patrick T. Ellinor, Lianjun Gao, Xiaoping Lin, Li Li, Lei Wang, Junjie Xiao, Yi Liu, Ying Liu, Shulong Zhang, Dandan Liang, Luying Peng, Thomas Jespersen, Yi-Han Chen
Am J Hum Genet. 2010 Jun 11; 86(6): 872–880. doi: 10.1016/j.ajhg.2010.04.017
PMCID:
PMC3032079
AbstractArticlePDF–1.4M
20.
G Protein βγ Gating Confers Volatile Anesthetic Inhibition to Kir3 Channels
Amanda M. Styer, Uyenlinh L. Mirshahi, Chuan Wang, Laura Girard, Taihao Jin, Diomedes E. Logothetis, Tooraj Mirshahi
J Biol Chem. 2010 Dec 31; 285(53): 41290–41299. Published online 2010 Nov 2. doi: 10.1074/jbc.M110.178541
PMCID:
PMC3009854
AbstractArticlePDF–1.2M

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