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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108666622.

KCTD1/KCTD15 complexes control ectodermal and neural crest cell functions, and their impairment causes aplasia cutis

Jackelyn R. Raymundo, Hui Zhang, Giovanni Smaldone, Wenjuan Zhu, Kathleen E. Daly, Benjamin J. Glennon, Giovanni Pecoraro, Marco Salvatore, William A. Devine, Cecilia W. Lo, Luigi Vitagliano, Alexander G. Marneros

J Clin Invest. 2024 Feb 15; 134(4): e174138. Published online 2023 Dec 19. doi: 10.1172/JCI174138

PMCID:: PMC10866662

Abstract Article PDF–143M

Select item 105532173.

Functional analysis of Collagen 17a1: A genetic modifier of junctional epidermolysis bullosa in mice

Thomas J. Sproule, Robert Y. Wilpan, Benjamin E. Low, Kathleen A. Silva, Deepak Reyon, J. Keith Joung, Michael V. Wiles, Derry C. Roopenian, John P. Sundberg

PLoS One. 2023; 18(10): e0292456. Published online 2023 Oct 5. doi: 10.1371/journal.pone.0292456

PMCID:: PMC10553217

Abstract Article PDF–5.8M

Select item 103620624.

MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters

Dongmei Wang, Haimin Li, Navdeep S. Chandel, Yali Dou, Rui Yi

Nat Commun. 2023; 14: 4404. Published online 2023 Jul 21. doi: 10.1038/s41467-023-40108-0

PMCID:: PMC10362062

Abstract Article PDF–9.3M

Select item 98528795.

Transcriptomic analysis of the upper lip and primary palate development in mice

Sini Cai, Nuo Si, Yanyang Wang, Ningbei Yin

Front Genet. 2022; 13: 1039850. Published online 2023 Jan 6. doi: 10.3389/fgene.2022.1039850

PMCID:: PMC9852879

Abstract Article PDF–7.2M

Select item 93600016.

Thy1 marks a distinct population of slow-cycling stem cells in the mouse epidermis

Elle Koren, Alona Feldman, Marianna Yusupova, Avihay Kadosh, Egor Sedov, Roi Ankawa, Yahav Yosefzon, Waseem Nasser, Stefanie Gerstberger, Liam B. Kimel, Noa Priselac, Samara Brown, Sam Sharma, Travis Gorenc, Ruby Shalom-Feuerstein, Hermann Steller, Tom Shemesh, Yaron Fuchs

Nat Commun. 2022; 13: 4628. Published online 2022 Aug 8. doi: 10.1038/s41467-022-31629-1

PMCID:: PMC9360001

Abstract Article PDF–14M

Select item 76580307.

Non-cell-autonomous activity of the hemidesmosomal protein BP180/collagen XVII in granulopoiesis in humanized NC16A mice

Lin Lin, Bin-Jin Hwang, Ning Li, Paul Googe, Luis A. Diaz, Ed. Miao, Barbara Vilen, Nancy E. Thomas, Jenny Ting, Zhi Liu

J Immunol. Author manuscript; available in PMC 2021 Nov 15.

Published in final edited form as: J Immunol. 2020 Nov 15; 205(10): 2786–2794. Published online 2020 Sep 30. doi: 10.4049/jimmunol.2000784

PMCID:: PMC7658030

Abstract Article PDF–2.1M

Select item 69087498.

The dysfunction of BP180/collagen XVII in keratinocytes promotes melanoma progression.

Bin-Jin Hwang, Yang Zhang, Jaime M Brozowski, Zhen Liu, Susan Burette, Kendall Lough, Christof C Smith, Yue Shan, Jinbo Chen, Ning Li, Scott Williams, Maureen Su, Paul Googe, Nancy E. Thomas, Zhi Liu

Oncogene. Author manuscript; available in PMC 2020 Feb 21.

Published in final edited form as: Oncogene. 2019 Dec; 38(50): 7491–7503. Published online 2019 Aug 21. doi: 10.1038/s41388-019-0961-9

PMCID:: PMC6908749

Abstract Article PDF–1.0M

Select item 63173129.

PRC1 preserves epidermal tissue integrity independently of PRC2

Idan Cohen, Dejian Zhao, Gopinathan Menon, Manabu Nakayama, Haruhiko Koseki, Deyou Zheng, Elena Ezhkova

Genes Dev. 2019 Jan 1; 33(1-2): 55–60. doi: 10.1101/gad.319939.118

PMCID:: PMC6317312

Abstract Article PDF–2.5M

Select item 601681310.

BP180 dysfunction triggers spontaneous skin inflammation in mice

Yang Zhang, Bin-Jin Hwang, Zhen Liu, Ning Li, Kendall Lough, Scott E. Williams, Jinbo Chen, Susan W. Burette, Luis A. Diaz, Maureen A. Su, Shengxiang Xiao, Zhi Liu

Proc Natl Acad Sci U S A. 2018 Jun 19; 115(25): 6434–6439. Published online 2018 Jun 4. doi: 10.1073/pnas.1721805115

PMCID:: PMC6016813

Abstract Article PDF–1.4M

Select item 550570311.

Type XVII collagen coordinates proliferation in the interfollicular epidermis

Mika Watanabe, Ken Natsuga, Wataru Nishie, Yasuaki Kobayashi, Giacomo Donati, Shotaro Suzuki, Yu Fujimura, Tadasuke Tsukiyama, Hideyuki Ujiie, Satoru Shinkuma, Hideki Nakamura, Masamoto Murakami, Michitaka Ozaki, Masaharu Nagayama, Fiona M Watt, Hiroshi Shimizu

eLife. 2017; 6: e26635. Published online 2017 Jul 11. doi: 10.7554/eLife.26635

PMCID:: PMC5505703

Abstract Article PDF–6.7M

Select item 548451912.

p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate

Rose Richardson, Karen Mitchell, Nigel L. Hammond, Maria Rosaria Mollo, Evelyn N. Kouwenhoven, Niki D. Wyatt, Ian J. Donaldson, Leo Zeef, Tim Burgis, Rognvald Blance, Simon J. van Heeringen, Hendrik G. Stunnenberg, Huiqing Zhou, Caterina Missero, Rose Anne Romano, Satrajit Sinha, Michael J. Dixon, Jill Dixon

PLoS Genet. 2017 Jun; 13(6): e1006828. Published online 2017 Jun 12. doi: 10.1371/journal.pgen.1006828

PMCID:: PMC5484519

Abstract Article PDF–22M

Select item 546724813.

WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation

Mingang Xu, Jeremy Horrell, Melinda Snitow, Jiawei Cui, Heather Gochnauer, Camille M. Syrett, Staci Kallish, John T. Seykora, Fei Liu, Dany Gaillard, Jonathan P. Katz, Klaus H. Kaestner, Brooke Levin, Corinne Mansfield, Jennifer E. Douglas, Beverly J. Cowart, Michael Tordoff, Fang Liu, Xuming Zhu, Linda A. Barlow, Adam I. Rubin, John A. McGrath, Edward E. Morrisey, Emily Y. Chu, Sarah E. Millar

Nat Commun. 2017; 8: 15397. Published online 2017 Jun 7. doi: 10.1038/ncomms15397

PMCID:: PMC5467248

Abstract Article PDF–8.8M

Select item 392366514.

Molecular Identification of Collagen 17a1 as a Major Genetic Modifier of Laminin Gamma 2 Mutation-Induced Junctional Epidermolysis Bullosa in Mice

Thomas J. Sproule, Jason A. Bubier, Fiorella C. Grandi, Victor Z. Sun, Vivek M. Philip, Caroline G. McPhee, Elisabeth B. Adkins, John P. Sundberg, Derry C. Roopenian

PLoS Genet. 2014 Feb; 10(2): e1004068. Published online 2014 Feb 13. doi: 10.1371/journal.pgen.1004068

PMCID:: PMC3923665

Abstract Article PDF–7.1M

Select item 391481515.

Transmembrane Collagen XVII Modulates Integrin Dependent Keratinocyte Migration via PI3K/Rac1 Signaling

Stefanie Löffek, Tiina Hurskainen, Joanna Jackow, Florian Christoph Sigloch, Oliver Schilling, Kaisa Tasanen, Leena Bruckner-Tuderman, Claus-Werner Franzke

PLoS One. 2014; 9(2): e87263. Published online 2014 Feb 5. doi: 10.1371/journal.pone.0087263

PMCID:: PMC3914815

Abstract Article PDF–1.0M

Select item 326134516.

Neutrophil elastase cleaves the murine hemidesmosomal protein BP180/type XVII collagen and generates degradation products that modulate experimental Bullous Pemphigoid

Lan Lin, Tomoko Betsuyaku, Lisa Heimbach, Ning Li, David Rubenstein, Steven D. Shapiro, Lijia An, George J. Giudice, Luis A. Diaz, Robert M. Senior, Zhi Liu

Matrix Biol. Author manuscript; available in PMC 2013 Jan 1.

Published in final edited form as: Matrix Biol. 2012 Jan; 31(1): 38–44. Published online 2011 Sep 25. doi: 10.1016/j.matbio.2011.09.003

PMCID:: PMC3261345

Abstract Article PDF–990K

Select item 324279117.

Collagen XXVII Organises the Pericellular Matrix in the Growth Plate

Darren A. Plumb, Laila Ferrara, Tanja Torbica, Lynnette Knowles, Aleksandr Mironov, Jr., Karl E. Kadler, Michael D. Briggs, Raymond P. Boot-Handford

PLoS One. 2011; 6(12): e29422. Published online 2011 Dec 19. doi: 10.1371/journal.pone.0029422

PMCID:: PMC3242791

Abstract Article PDF–10M

Select item 317805918.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 315461619.

Comparative gene expression analysis of genital tubercle development reveals a putative appendicular Wnt7 network for the epidermal differentiation

Han Sheng Chiu, John C. Szucsik, Kylie M. Georgas, Julia L. Jones, Bree A. Rumballe, Dave Tang, Sean M. Grimmond, Alfor G. Lewis, Bruce J. Aronow, James L. Lessard, Melissa H. Little

Dev Biol. Author manuscript; available in PMC 2011 Aug 15.

Published in final edited form as: Dev Biol. 2010 Aug 15; 344(2): 1071–1087. Published online 2010 May 24. doi: 10.1016/j.ydbio.2010.05.495

PMCID:: PMC3154616

Abstract Article PDF–2.3M

Select item 302253420.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

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