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Items: 1 to 20 of 51

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Control of NAD+ homeostasis by autophagic flux modulates mitochondrial and cardiac function
Quanjiang Zhang, Zhonggang Li, Qiuxia Li, Samuel AJ Trammell, Mark S Schmidt, Karla Maria Pires, Jinjin Cai, Yuan Zhang, Helena Kenny, Sihem Boudina, Charles Brenner, E Dale Abel
EMBO J. 2024 Feb; 43(3): 362–390. Published online 2024 Jan 11. doi: 10.1038/s44318-023-00009-w
PMCID:
PMC10897141
AbstractArticlePDF–4.3M
3.
Mitophagy restricts BAX/BAK-independent, Parkin-mediated apoptosis
Giovanni Quarato, Luigi Mari, Nicholas J. Barrows, Mao Yang, Sebastian Ruehl, Mark J. Chen, Cliff S. Guy, Jonathan Low, Taosheng Chen, Douglas R. Green
Sci Adv. 2023 May; 9(21): eadg8156. Published online 2023 May 24. doi: 10.1126/sciadv.adg8156
PMCID:
PMC10208567
AbstractArticlePDF–1.7M
4.
Evaluating mitophagy in embryonic stem cells by using fluorescence-based imaging
Kun Liu, Xing Li, Zheng Li, Jiani Cao, Xiaoyan Li, Youqing Xu, Lei Liu, Tongbiao Zhao
Front Cell Dev Biol. 2022; 10: 910464. Published online 2022 Sep 15. doi: 10.3389/fcell.2022.910464
PMCID:
PMC9520453
AbstractArticlePDF–1.9M
5.
The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery
Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane
Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054
PMCID:
PMC9015699
AbstractArticlePDF–3.3M
6.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
7.
Autophagy Regulates Phagocytosis by Modulating the Expression of Scavenger Receptors
Diana L. Bonilla, Abhisek Bhattacharya, Youbao Sha, Yi Xu, Qian Xiang, Arshad Kan, Chinnaswamy Jagannath, Masaaki Komatsu, N. Tony Eissa
Immunity. Author manuscript; available in PMC 2021 Apr 21.
Published in final edited form as: Immunity. 2013 Sep 19; 39(3): 537–547. Published online 2013 Sep 12. doi: 10.1016/j.immuni.2013.08.026
PMCID:
PMC8059138
AbstractArticlePDF–1.9M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
10.
Autophagy Ablation in Adipocytes Induces Insulin Resistance and Reveals Roles for Lipid Peroxide and Nrf2 Signaling in Adipose-Liver Crosstalk
Jinjin Cai, Karla M. Pires, Maroua Ferhat, Bhagirath Chaurasia, Ma´rcio A. Buffolo, Rana Smalling, Ashot Sargsyan, Donald L. Atkinson, Scott A. Summers, Timothy E. Graham, Sihem Boudina
Cell Rep. Author manuscript; available in PMC 2019 Oct 21.
Published in final edited form as: Cell Rep. 2018 Nov 13; 25(7): 1708–1717.e5. doi: 10.1016/j.celrep.2018.10.040
PMCID:
PMC6802939
AbstractArticlePDF–2.1M
11.
Suppression of FIP200 and autophagy by tumor-derived lactate promotes naïve T cell apoptosis and affects tumor immunity
Houjun Xia, Wei Wang, Joel Crespo, Ilona Kryczek, Wei Li, Shuang Wei, Zhaoqun Bian, Tomasz Maj, Mingxiao He, Rebecca J. Liu, Youwen He, Ramandeep Rattan, Adnan Munkarah, Jun-Lin Guan, Weiping Zou
Sci Immunol. Author manuscript; available in PMC 2018 Jan 19.
Published in final edited form as: Sci Immunol. 2017 Nov 17; 2(17): eaan4631. doi: 10.1126/sciimmunol.aan4631
PMCID:
PMC5774333
AbstractArticlePDF–3.6M
12.
Oxidation of Atg3 and Atg7 mediates inhibition of autophagy
Karen Frudd, Thomas Burgoyne, Joseph Robert Burgoyne
Nat Commun. 2018; 9: 95. Published online 2018 Jan 8. doi: 10.1038/s41467-017-02352-z
PMCID:
PMC5758830
AbstractArticlePDF–2.9M
13.
BNIP3- and BNIP3L-Mediated Mitophagy Promotes the Generation of Natural Killer Cell Memory
Timothy E. O’Sullivan, Lexus R. Johnson, Helen H. Kang, Joseph C. Sun
Immunity. Author manuscript; available in PMC 2017 Dec 20.
Published in final edited form as: Immunity. 2015 Aug 18; 43(2): 331–342. Published online 2015 Aug 4. doi: 10.1016/j.immuni.2015.07.012
PMCID:
PMC5737626
AbstractArticlePDF–1.5M
14.
Endothelial cell autophagy maintains shear-stress-induced nitric oxide generation via glycolysis-dependent purinergic signaling to eNOS
Leena P Bharath, Jae Min Cho, Seul-Ki Park, Ting Ruan, Youyou Li, Robert Mueller, Tyler Bean, Van Reese, Russel S Richardson, Jinjin Cai, Ashot Sargsyan, Karla Pires, Pon Velayutham Anandh Babu, Sihem Boudina, Timothy E Graham, J David Symons
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2018 Sep 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2017 Sep; 37(9): 1646–1656. Published online 2017 Jul 6. doi: 10.1161/ATVBAHA.117.309510
PMCID:
PMC5693355
AbstractArticlePDF–2.8M
15.
Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells
Thaiz Rivera Vargas, Zhijian Cai, Yingying Shen, Magalie Dosset, Isis Benoit-Lizon, Tiffany Martin, Aurélie Roussey, Richard A. Flavell, François Ghiringhelli, Lionel Apetoh
Nat Commun. 2017; 8: 559. Published online 2017 Sep 15. doi: 10.1038/s41467-017-00468-w
PMCID:
PMC5602674
AbstractArticlePDF–1.2M
16.
High autophagic flux guards ESC identity through coordinating autophagy machinery gene program by FOXO1
Pinglei Liu, Kun Liu, Haifeng Gu, Weixu Wang, Jiaqi Gong, Yingjie Zhu, Qian Zhao, Jiani Cao, Chunseng Han, Fei Gao, Quan Chen, Wei Li, Jianwei Jiao, Baoyang Hu, Qi Zhou, Tongbiao Zhao
Cell Death Differ. 2017 Oct; 24(10): 1672–1680. Published online 2017 Jun 16. doi: 10.1038/cdd.2017.90
PMCID:
PMC5596427
AbstractArticlePDF–2.0M
17.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
18.
Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1
Rebecca Rojansky, Moon-Yong Cha, David C Chan
eLife. 2016; 5: e17896. Published online 2016 Nov 17. doi: 10.7554/eLife.17896
PMCID:
PMC5127638
AbstractArticlePDF–5.5M
19.
ATG3-dependent autophagy mediates mitochondrial homeostasis in pluripotency acquirement and maintenance
Kun Liu, Qian Zhao, Pinglei Liu, Jiani Cao, Jiaqi Gong, Chaoqun Wang, Weixu Wang, Xiaoyan Li, Hongyan Sun, Chao Zhang, Yufei Li, Minggui Jiang, Shaohua Zhu, Qingyuan Sun, Jianwei Jiao, Baoyang Hu, Xiaoyang Zhao, Wei Li, Quan Chen, Qi Zhou, Tongbiao Zhao
Autophagy. 2016; 12(11): 2000–2008. Published online 2016 Aug 11. doi: 10.1080/15548627.2016.1212786
PMCID:
PMC5103358
AbstractArticlePDF–1.1M
20.
Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity
Owen M. Siggs, Alexander Stockenhuber, Mukta Deobagkar-Lele, Katherine R. Bull, Tanya L. Crockford, Bethany L. Kingston, Greg Crawford, Consuelo Anzilotti, Violetta Steeples, Sahar Ghaffari, Gabor Czibik, Mohamed Bellahcene, Hugh Watkins, Houman Ashrafian, Benjamin Davies, Angela Woods, David Carling, Arash Yavari, Bruce Beutler, Richard J. Cornall
Proc Natl Acad Sci U S A. 2016 Jun 28; 113(26): E3706–E3715. Published online 2016 Jun 14. doi: 10.1073/pnas.1607592113
PMCID:
PMC4932993
AbstractArticlePDF–2.0M

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