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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 104815742.

RGS5 augments astrocyte activation and facilitates neuroinflammation via TNF signaling

Shu Yin, Xin-yue Ma, Ying-feng Sun, Yan-qing Yin, Ying Long, Chun-lai Zhao, Jun-wei Ma, Sen Li, Yan Hu, Ming-tao Li, Gang Hu, Jia-wei Zhou

J Neuroinflammation. 2023; 20: 203. Published online 2023 Sep 6. doi: 10.1186/s12974-023-02884-w

PMCID:: PMC10481574

Abstract Article PDF–10M

Select item 102113743.

Dual loss of regulator of G protein signaling 2 and 5 exacerbates ventricular myocyte arrhythmias and disrupts the fine-tuning of G_i/o signaling

Shelby A. Dahlen, Tyler F. Bernadyn, Alethia J. Dixon, Bo Sun, Jingsheng Xia, Elizabeth A. Owens, Patrick Osei-Owusu

J Mol Cell Cardiol. Author manuscript; available in PMC 2023 May 25.

Published in final edited form as: J Mol Cell Cardiol. 2022 Sep; 170: 34–46. Published online 2022 Jun 2. doi: 10.1016/j.yjmcc.2022.05.009

PMCID:: PMC10211374

Abstract Article PDF–2.2M

Select item 100278554.

Single-cell transcriptomics uncovers a non-autonomous Tbx1-dependent genetic program controlling cardiac neural crest cell development

Christopher De Bono, Yang Liu, Alexander Ferrena, Aneesa Valentine, Deyou Zheng, Bernice E. Morrow

Nat Commun. 2023; 14: 1551. Published online 2023 Mar 21. doi: 10.1038/s41467-023-37015-9

PMCID:: PMC10027855

Abstract Article PDF–19M

Select item 95531235.

Developmental heterogeneity of embryonic neuroendocrine chromaffin cells and their maturation dynamics

Natalia Akkuratova, Louis Faure, Polina Kameneva, Maria Eleni Kastriti, Igor Adameyko

Front Endocrinol (Lausanne) 2022; 13: 1020000. Published online 2022 Sep 27. doi: 10.3389/fendo.2022.1020000

PMCID:: PMC9553123

Abstract Article PDF–28M

Select item 89422296.

A regulator of G protein signaling 5 marked subpopulation of vascular smooth muscle cells is lost during vascular disease

Ya-Kun Gao, Rui-Juan Guo, Xin Xu, Xiao-Fu Huang, Yu Song, Dan-Dan Zhang, Ning Chen, Xiao-Wei Wang, Chen-Xi Liang, Peng Kong, Mei Han

PLoS One. 2022; 17(3): e0265132. Published online 2022 Mar 23. doi: 10.1371/journal.pone.0265132

PMCID:: PMC8942229

Abstract Article PDF–3.1M

Select item 84308587.

RGS5 Determines Neutrophil Migration in the Acute Inflammatory Phase of Bleomycin-Induced Lung Injury

Neha Sharma, Chandran Nagaraj, Bence M. Nagy, Leigh M. Marsh, Natalie Bordag, Diana Zabini, Malgorzata Wygrecka, Walter Klepetko, Elisabeth Gschwandtner, Guillem Genové, Akos Heinemann, E Kenneth Weir, Grazyna Kwapiszewska, Horst Olschewski, Andrea Olschewski

Int J Mol Sci. 2021 Sep; 22(17): 9342. Published online 2021 Aug 28. doi: 10.3390/ijms22179342

PMCID:: PMC8430858

Abstract Article PDF–10M

Select item 83553378.

The developing mouse coronal suture at single-cell resolution

D’Juan T. Farmer, Hana Mlcochova, Yan Zhou, Nils Koelling, Guanlin Wang, Neil Ashley, Helena Bugacov, Hung-Jhen Chen, Riana Parvez, Kuo-Chang Tseng, Amy E. Merrill, Robert E. Maxson, Jr., Andrew O. M. Wilkie, J. Gage Crump, Stephen R. F. Twigg

Nat Commun. 2021; 12: 4797. Published online 2021 Aug 10. doi: 10.1038/s41467-021-24917-9

PMCID:: PMC8355337

Abstract Article PDF–9.6M

Select item 83063269.

RGS5 Attenuates Baseline Activity of ERK1/2 and Promotes Growth Arrest of Vascular Smooth Muscle Cells

Eda Demirel, Caroline Arnold, Jaspal Garg, Marius Andreas Jäger, Carsten Sticht, Rui Li, Hanna Kuk, Nina Wettschureck, Markus Hecker, Thomas Korff

Cells. 2021 Jul; 10(7): 1748. Published online 2021 Jul 11. doi: 10.3390/cells10071748

PMCID:: PMC8306326

Abstract Article PDF–20M

Select item 821480910.

A cellular and spatial map of the choroid plexus across brain ventricles and ages

Neil Dani, Rebecca H. Herbst, Cristin McCabe, Gilad Green, Karol Kaiser, Joshua Head, Jin Cui, Frederick B. Shipley, Ahram Jang, Danielle Dionne, Lan Nguyen, Christopher Rodman, Samantha J. Riesenfeld, Jan Prochazka, Michaela Prochazkova, Radislav Sedlacek, Feng Zhang, Vitezslav Bryja, Orit Rozenblatt-Rosen, Naomi Habib, Aviv Regev, Maria K. Lehtinen

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3056–3074.e21. Published online 2021 Apr 30. doi: 10.1016/j.cell.2021.04.003

PMCID:: PMC8214809

Abstract Article PDF–3.5M

Select item 821053611.

Parathyroid-targeted overexpression of Regulator of G-Protein Signaling 5 (RGS5) causes hyperparathyroidism in transgenic mice.

Nariman Balenga, James Koh, Pedram Azimzadeh, Joyce Hogue, Mostafa Gabr, Joseph P. Stains, John A. Olson, Jr.

J Bone Miner Res. Author manuscript; available in PMC 2021 Jun 17.

Published in final edited form as: J Bone Miner Res. 2019 May; 34(5): 955–963. Published online 2019 Feb 28. doi: 10.1002/jbmr.3674

PMCID:: PMC8210536

Abstract Article PDF–1.7M

Select item 801275712.

Absence of Rgs5 Influences the Spatial and Temporal Fluctuation of Cardiac Repolarization in Mice

Zi-liang Song, Yang Liu, Xu Liu, Mu Qin

Front Physiol. 2021; 12: 622084. Published online 2021 Mar 18. doi: 10.3389/fphys.2021.622084

PMCID:: PMC8012757

Abstract Article PDF–4.8M

Select item 786516813.

Single-cell atlas of developing murine adrenal gland reveals relation of Schwann cell precursor signature to neuroblastoma phenotype

Evelyn S. Hanemaaijer, Thanasis Margaritis, Karin Sanders, Frank L. Bos, Tito Candelli, Hanin Al-Saati, Max M. van Noesel, Friederike A. G. Meyer-Wentrup, Marc van de Wetering, Frank C. P. Holstege, Hans Clevers

Proc Natl Acad Sci U S A. 2021 Feb 2; 118(5): e2022350118. Published online 2021 Jan 26. doi: 10.1073/pnas.2022350118

PMCID:: PMC7865168

Abstract Article PDF–3.3M

Select item 772698714.

Regulator of G‐Protein Signaling 5 Maintains Brain Endothelial Cell Function in Focal Cerebral Ischemia

Nikola Sladojevic, Brian Yu, James K. Liao

J Am Heart Assoc. 2020 Sep 15; 9(18): e017533. Published online 2020 Sep 2. doi: 10.1161/JAHA.120.017533

PMCID:: PMC7726987

Abstract Article PDF–11M

Select item 715473615.

Parenchymal pericytes are not the major contributor of extracellular matrix in the fibrotic scar after stroke in male mice

Michaela Roth, Andreas Enström, Candice Aghabeick, Robert Carlsson, Guillem Genové, Gesine Paul

J Neurosci Res. 2020 May; 98(5): 826–842. Published online 2019 Nov 22. doi: 10.1002/jnr.24557

PMCID:: PMC7154736

Abstract Article PDF–3.8M

Select item 671969716.

Single-cell analysis of cardiogenesis reveals basis for organ level developmental defects

T. Yvanka de Soysa, Sanjeev S. Ranade, Satoshi Okawa, Srikanth Ravichandran, Yu Huang, Hazel T. Salunga, Amelia Schricker, Antonio Del Sol, Casey A. Gifford, Deepak Srivastava

Nature. Author manuscript; available in PMC 2020 Jan 24.

Published in final edited form as: Nature. 2019 Aug; 572(7767): 120–124. Published online 2019 Jul 24. doi: 10.1038/s41586-019-1414-x

PMCID:: PMC6719697

Abstract Article PDF–8.9M

Select item 666298117.

Regulator of G-protein signaling 5 regulates the shift from perivascular to parenchymal pericytes in the chronic phase after stroke

Michaela Roth, Abderahim Gaceb, Andreas Enström, Thomas Padel, Guillem Genové, Ilknur Özen, Gesine Paul

FASEB J. 2019 Aug; 33(8): 8990–8998. Published online 2019 Apr 30. doi: 10.1096/fj.201900153R

PMCID:: PMC6662981

Abstract Article

Select item 651212318.

Regulator of G Protein Signaling 2 Facilitates Uterine Artery Adaptation During Pregnancy in Mice

Jennifer N. Koch, Shelby A. Dahlen, Elizabeth A. Owens, Patrick Osei‐Owusu

J Am Heart Assoc. 2019 May 7; 8(9): e010917. Published online 2019 Apr 29. doi: 10.1161/JAHA.118.010917

PMCID:: PMC6512123

Abstract Article PDF–2.6M

Select item 611679519.

Loss of Regulator of G-Protein Signaling 5 Leads to Neurovascular Protection in Stroke

Ilknur Özen, Michaela Roth, Marco Barbariga, Abderahim Gaceb, Tomas Deierborg, Guillem Genové, Gesine Paul

Stroke. 2018 Sep; 49(9): 2182–2190. Published online 2018 Aug 3. doi: 10.1161/STROKEAHA.118.020124

PMCID:: PMC6116795

Abstract Article PDF–5.5M

Select item 610212720.

Regulator of G protein signaling 5 restricts neutrophil chemotaxis and trafficking

Eunice C. Chan, Chunguang Ren, Zhihui Xie, Joseph Jude, Tolga Barker, Cynthia A. Koziol-White, Michelle Ma, Reynold A. Panettieri, Jr., Dianqing Wu, Helene F. Rosenberg, Kirk M. Druey

J Biol Chem. 2018 Aug 17; 293(33): 12690–12702. Published online 2018 Jun 21. doi: 10.1074/jbc.RA118.002404

PMCID:: PMC6102127

Abstract Article PDF–2.9M

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