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Select item 109586751.

SERPINE2 promotes liver cancer metastasis by inhibiting c‐Cbl‐mediated EGFR ubiquitination and degradation

Shiyu Zhang, Xing Jia, Haojiang Dai, Xingxin Zhu, Wenfeng Song, Suchen Bian, Hao Wu, Shinuo Chen, Yangbo Tang, Junran Chen, Cheng Jin, Mengqiao Zhou, Haiyang Xie, Shusen Zheng, Penghong Song

Cancer Commun (Lond) 2024 Mar; 44(3): 384–407. Published online 2024 Feb 26. doi: 10.1002/cac2.12527

PMCID:: PMC10958675

Abstract Article PDF–15M

Select item 108815192.

Integrating artificial intelligence in osteosarcoma prognosis: the prognostic significance of SERPINE2 and CPT1B biomarkers

Haishun Qu, Jie Jiang, Xinli Zhan, Yunxiao Liang, Quan Guo, Peifeng Liu, Ling Lu, Yanwei Yang, Weicheng Xu, Yitian Zhang, Shaohang Lan, Zeshan Chen, Yuanhong Lu, Yufu Ou, Yijue Qin

Sci Rep. 2024; 14: 4318. Published online 2024 Feb 21. doi: 10.1038/s41598-024-54222-6

PMCID:: PMC10881519

Abstract Article PDF–13M

Select item 102374223.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 99367224.

Targeting tumor exosomal circular RNA cSERPINE2 suppresses breast cancer progression by modulating MALT1-NF-𝜅B-IL-6 axis of tumor-associated macrophages

Boxuan Zhou, Zhaohong Mo, Guie Lai, Xiaohong Chen, Ruixi Li, Runxin Wu, Jia Zhu, Fang Zheng

J Exp Clin Cancer Res. 2023; 42: 48. Published online 2023 Feb 17. doi: 10.1186/s13046-023-02620-5

PMCID:: PMC9936722

Abstract Article PDF–16M

Select item 97340005.

Upregulation of SERPINE2 Results in Poor Prognosis of Hepatoblastoma via Promoting Invasion Abilities

Guoyou Zou, Yong Lv, Meng Kong, Bo Xiang, Jing Chen

Dis Markers. 2022; 2022: 2283541. Published online 2022 Dec 2. doi: 10.1155/2022/2283541

PMCID:: PMC9734000

Abstract Article PDF–2.5M

Select item 93485766.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 92316237.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 89566048.

CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity

Julia Joung, Paul C. Kirchgatterer, Ankita Singh, Jang H. Cho, Suchita P. Nety, Rebecca C. Larson, Rhiannon K. Macrae, Rebecca Deasy, Yuen-Yi Tseng, Marcela V. Maus, Feng Zhang

Nat Commun. 2022; 13: 1606. Published online 2022 Mar 25. doi: 10.1038/s41467-022-29205-8

PMCID:: PMC8956604

Abstract Article PDF–3.9M

Select item 88570499.

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

Tara E. Tracy, Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q. Trojanowski, Virginia M.Y. Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J. Krogan, Daniel H. Geschwind, Li Gan

Cell. Author manuscript; available in PMC 2022 Feb 19.

Published in final edited form as: Cell. 2022 Feb 17; 185(4): 712–728.e14. Published online 2022 Jan 20. doi: 10.1016/j.cell.2021.12.041

PMCID:: PMC8857049

Abstract Article PDF–3.6M

Select item 819174210.

Comprehensive proteomic characterization of stem cell-derived extracellular matrices

Héloïse Ragelle, Alexandra Naba, Benjamin L. Larson, Fangheng Zhou, Miralem Prijic, Charles A. Whittaker, Amanda Del Rosario, Robert Langer, Richard O. Hynes, Daniel G. Anderson

Biomaterials. Author manuscript; available in PMC 2021 Jun 10.

Published in final edited form as: Biomaterials. 2017 Jun; 128: 147–159. Published online 2017 Mar 7. doi: 10.1016/j.biomaterials.2017.03.008

PMCID:: PMC8191742

Abstract Article PDF–1.5M

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 773733112.

High expression level of serpin peptidase inhibitor clade E member 2 is associated with poor prognosis in lung adenocarcinoma

Ryota Dokuni, Tatsuya Nagano, Naoe Jimbo, Hiroki Sato, Tatsunori Kiriu, Yuichiro Yasuda, Masatsugu Yamamoto, Motoko Tachihara, Kazuyuki Kobayashi, Yoshimasa Maniwa, Yoshihiro Nishimura

Respir Res. 2020; 21: 331. Published online 2020 Dec 14. doi: 10.1186/s12931-020-01597-5

PMCID:: PMC7737331

Abstract Article PDF–1.2M

Select item 765717913.

Genome‐wide association study of chemotherapeutic agent‐induced severe neutropenia/leucopenia for patients in Biobank Japan

Siew‐Kee Low, Suyoun Chung, Atsushi Takahashi, Hitoshi Zembutsu, Taisei Mushiroda, Michiaki Kubo, Yusuke Nakamura

Cancer Sci. 2013 Aug; 104(8): 1074–1082. Published online 2013 Jun 10. doi: 10.1111/cas.12186

PMCID:: PMC7657179

Abstract Article PDF–225K

Select item 739249114.

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination

Gangliang Wang, Shuai Chen, Ziang Xie, Shuying Shen, Wenbin Xu, Wenxiang Chen, Xiang Li, Yizheng Wu, Liangping Li, Bin Liu, Xianjun Ding, An Qin, Shunwu Fan

Ann Rheum Dis. 2020 Aug; 79(8): 1111–1120. Published online 2020 May 14. doi: 10.1136/annrheumdis-2019-216911

PMCID:: PMC7392491

Abstract Article PDF–14M

Select item 673384115.

Protease Nexin I is a feedback regulator of EGF/PKC/MAPK/EGR1 signaling in breast cancer cells metastasis and stemness

Tingting Tang, Qinhua Zhu, Xinping Li, Gaole Zhu, Siwei Deng, Yingshan Wang, Lingyu Ni, Xinyuan Chen, Yanfeng Zhang, Tiansong Xia, Ke Zen, Yi Pan, Liang Jin

Cell Death Dis. 2019 Sep; 10(9): 649. Published online 2019 Sep 9. doi: 10.1038/s41419-019-1882-9

Correction in:: Cell Death Dis. 2020 Jan; 11(1): 13.

PMCID:: PMC6733841

Abstract Article PDF–4.6M

Select item 666898116.

Circ‐SERPINE2 promotes the development of gastric carcinoma by sponging miR‐375 and modulating YWHAZ

Jianing Liu, Suzhen Song, Sen Lin, Mingbao Zhang, Yating Du, Dongdong Zhang, Weihua Xu, Hongbo Wang

Cell Prolif. 2019 Jul; 52(4): e12648. Published online 2019 Jun 14. doi: 10.1111/cpr.12648

PMCID:: PMC6668981

Abstract Article PDF–2.9M

Select item 657955317.

CircSERPINE2 protects against osteoarthritis by targeting miR-1271 and ETS-related gene

Shuying Shen, Yizheng Wu, Junxin Chen, Ziang Xie, Kangmao Huang, Gangliang Wang, Yute Yang, Weiyu Ni, Zhijun Chen, Peihua Shi, Yan Ma, Shunwu Fan

Ann Rheum Dis. 2019 Jun; 78(6): 826–836. Published online 2019 Mar 28. doi: 10.1136/annrheumdis-2018-214786

PMCID:: PMC6579553

Abstract Article PDF–14M

Select item 582371618.

ZEB1-repressed microRNAs inhibit autocrine signaling that promotes vascular mimicry of breast cancer cells

E M Langer, N D Kendsersky, C J Daniel, G M Kuziel, C Pelz, K M Murphy, M R Capecchi, R C Sears

Oncogene. 2018 Feb 22; 37(8): 1005–1019. Published online 2017 Oct 30. doi: 10.1038/onc.2017.356

PMCID:: PMC5823716

Abstract Article PDF–3.8M

Select item 579976819.

A slow-cycling subpopulation of melanoma cells with highly invasive properties

M Perego, M Maurer, J X Wang, S Shaffer, A C Müller, K Parapatics, L Li, D Hristova, S Shin, F Keeney, S Liu, X Xu, A Raj, J K Jensen, K L Bennett, S N Wagner, R Somasundaram, M Herlyn

Oncogene. 2018 Jan 18; 37(3): 302–312. Published online 2017 Sep 18. doi: 10.1038/onc.2017.341

PMCID:: PMC5799768

Abstract Article PDF–2.5M

Select item 554797320.

miR-199a-3p is involved in the pathogenesis and progression of diabetic neuropathy through downregulation of SerpinE2

Ying-Bo Li, Qun Wu, Jie Liu, Yong-Zhi Fan, Kai-Feng Yu, Yi Cai

Mol Med Rep. 2017 Sep; 16(3): 2417–2424. Published online 2017 Jun 28. doi: 10.3892/mmr.2017.6874

PMCID:: PMC5547973

Abstract Article PDF–1.1M

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