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Select item 100729061.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 91714112.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80651224.

Aggressive and recurrent ovarian cancers upregulate ephrinA5, a non-canonical effector of EphA2 signaling duality

Joonas Jukonen, Lidia Moyano-Galceran, Katrin Höpfner, Elina A. Pietilä, Laura Lehtinen, Kaisa Huhtinen, Erika Gucciardo, Johanna Hynninen, Sakari Hietanen, Seija Grénman, Päivi M. Ojala, Olli Carpén, Kaisa Lehti

Sci Rep. 2021; 11: 8856. Published online 2021 Apr 23. doi: 10.1038/s41598-021-88382-6

PMCID:: PMC8065122

Abstract Article PDF–4.3M

Select item 71699835.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 70822246.

Polycomb-mediated repression of EphrinA5 promotes growth and invasion of glioblastoma

Barbara Ricci, Thomas O. Millner, Nicola Pomella, Xinyu Zhang, Loredana Guglielmi, Sara Badodi, Dario Ceric, Carolina Gemma, Erica Cognolato, Ying Zhang, Sebastian Brandner, Michael R. Barnes, Silvia Marino

Oncogene. 2020; 39(12): 2523–2538. Published online 2020 Jan 27. doi: 10.1038/s41388-020-1161-3

PMCID:: PMC7082224

Abstract Article PDF–6.3M

Select item 67828897.

Regulation of Learning by EphA Receptors: a Protein Targeting Study

R. Gerlai, N. Shinsky, A. Shih, P. Williams, J. Winer, M. Armanini, B. Cairns, J. Winslow, W.-Q. Gao, H. S. Phillips

J Neurosci. 1999 Nov 1; 19(21): 9538–9549. doi: 10.1523/JNEUROSCI.19-21-09538.1999

PMCID:: PMC6782889

Abstract Article PDF–438K

Select item 67826618.

Ephrin-A Binding and EphA Receptor Expression Delineate the Matrix Compartment of the Striatum

L. Scott Janis, Robert M. Cassidy, Lawrence F. Kromer

J Neurosci. 1999 Jun 15; 19(12): 4962–4971. doi: 10.1523/JNEUROSCI.19-12-04962.1999

PMCID:: PMC6782661

Abstract Article PDF–1.0M

Select item 62982549.

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

Emmy Van Quickelberghe, Delphine De Sutter, Geert van Loo, Sven Eyckerman, Kris Gevaert

Sci Data. 2018; 5: 180289. Published online 2018 Dec 18. doi: 10.1038/sdata.2018.289

PMCID:: PMC6298254

Abstract Article PDF–1.4M

Select item 553161110.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 549522511.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 493237312.

Exosomes mediate cell contact–independent ephrin-Eph signaling during axon guidance

Jingyi Gong, Roman Körner, Louise Gaitanos, Rüdiger Klein

J Cell Biol. 2016 Jul 4; 214(1): 35–44. doi: 10.1083/jcb.201601085

PMCID:: PMC4932373

Abstract Article PDF–2.0M

Select item 484160713.

High-throughput analyses of hnRNP H1 dissects its multi-functional aspect

Philip J. Uren, Emad Bahrami-Samani, Patricia Rosa de Araujo, Christine Vogel, Mei Qiao, Suzanne C. Burns, Andrew D. Smith, Luiz O. F. Penalva

RNA Biol. 2016 Apr; 13(4): 400–411. Published online 2016 Jan 13. doi: 10.1080/15476286.2015.1138030

PMCID:: PMC4841607

Abstract Article PDF–1.6M

Select item 443903714.

Distinctive Structure of the EphA3/Ephrin-A5 Complex Reveals a Dual Mode of Eph Receptor Interaction for Ephrin-A5

Garry Jason Forse, Maria Loressa Uson, Fariborz Nasertorabi, Anand Kolatkar, Ilaria Lamberto, Elena Bianca Pasquale, Peter Kuhn

PLoS One. 2015; 10(5): e0127081. Published online 2015 May 20. doi: 10.1371/journal.pone.0127081

PMCID:: PMC4439037

Abstract Article PDF–5.3M

Select item 394102115.

Structurally encoded intraclass differences in EphA clusters drive distinct cell responses

Elena Seiradake, Andreas Schaupp, Daniel del Toro Ruiz, Rainer Kaufmann, Nikolaos Mitakidis, Karl Harlos, A Radu Aricescu, Rüdiger Klein, E Yvonne Jones

Nat Struct Mol Biol. Author manuscript; available in PMC 2014 Mar 4.

Published in final edited form as: Nat Struct Mol Biol. 2013 Aug; 20(8): 958–964. Published online 2013 Jun 30. doi: 10.1038/nsmb.2617

PMCID:: PMC3941021

Abstract Article PDF–2.7M

Select item 384475116.

A TrkB/EphrinA Interaction Controls Retinal Axon Branching and Synaptogenesis

Katharine J. M. Marler, Elena Becker-Barroso, Albert Martínez, Marta Llovera, Corinna Wentzel, Subathra Poopalasundaram, Robert Hindges, Eduardo Soriano, Joan Comella, Uwe Drescher

J Neurosci. 2008 Nov 26; 28(48): 12700–12712. doi: 10.1523/JNEUROSCI.1915-08.2008

PMCID:: PMC3844751

Abstract Article PDF–845K

Select item 376751717.

Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5

Kai Xu, Dorothea Tzvetkova-Robev, Yan Xu, Yehuda Goldgur, Yee-Peng Chan, Juha P. Himanen, Dimitar B. Nikolov

Proc Natl Acad Sci U S A. 2013 Sep 3; 110(36): 14634–14639. Published online 2013 Aug 19. doi: 10.1073/pnas.1311000110

PMCID:: PMC3767517

Abstract Article PDF–1.6M

Select item 367296018.

An extracellular steric seeding mechanism for Eph-ephrin signalling platform assembly

Elena Seiradake, Karl Harlos, Geoff Sutton, A. Radu Aricescu, E. Yvonne Jones

Nat Struct Mol Biol. Author manuscript; available in PMC 2013 Jun 5.

Published in final edited form as: Nat Struct Mol Biol. 2010 Apr; 17(4): 398–402. Published online 2010 Mar 14. doi: 10.1038/nsmb.1782

PMCID:: PMC3672960

Abstract Article PDF–2.8M

Select item 366173919.

APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study

Vijay K. Ramanan, Shannon L. Risacher, Kwangsik Nho, Sungeun Kim, Shanker Swaminathan, Li Shen, Tatiana M. Foroud, Hakon Hakonarson, Matthew J. Huentelman, Paul S. Aisen, Ronald C. Petersen, Robert C. Green, Clifford R. Jack, Robert A. Koeppe, William J. Jagust, Michael W. Weiner, Andrew J. Saykin

Mol Psychiatry. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Mol Psychiatry. 2014 Mar; 19(3): 351–357. Published online 2013 Feb 19. doi: 10.1038/mp.2013.19

PMCID:: PMC3661739

Abstract Article PDF–1.0M

Select item 356689820.

Further analysis of the lens of ephrin-A5^−/− mice: development of postnatal defects

Alexander I. Son, Margaret A. Cooper, Michal Sheleg, Yuhai Sun, Norman J. Kleiman, Renping Zhou

Mol Vis. 2013; 19: 254–266. Published online 2013 Feb 3.

PMCID:: PMC3566898

Abstract Article PDF–6.9M

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