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Select item 91616131.

Carriage of mutations R462Q (rs 486907) and D541E (rs 627928) of the RNASEL gene and risk factors in patients with prostate cancer in Burkina Faso

Essonan Kadanga, Abdou Azaque Zouré, Théodora M. Zohoncon, Lassina Traoré, Bienvenu Désiré Ky, Albert Théophane Yonli, Djé Djénèba Aïda Traoré, Bapio Valery Jean Télesphore Elvira Bazié, Herman Karim Sombié, Pegdwendé Abel Sorgho, Sessi Frida Appoline Tovo, Kalifou Traoré, Teega-Wendé Clarisse Ouedraogo, Florencia W. Djigma, Jacques Simpore

BMC Med Genomics. 2022; 15: 123. Published online 2022 Jun 2. doi: 10.1186/s12920-022-01279-9

PMCID:: PMC9161613

Abstract Article PDF–1.2M

Select item 81792022.

Zika virus employs the host antiviral RNase L protein to support replication factory assembly

Jillian N. Whelan, Nicholas A. Parenti, Joshua Hatterschide, David M. Renner, Yize Li, Hanako M. Reyes, Beihua Dong, Erick R. Perez, Robert H. Silverman, Susan R. Weiss

Proc Natl Acad Sci U S A. 2021 Jun 1; 118(22): e2101713118. Published online 2021 May 24. doi: 10.1073/pnas.2101713118

PMCID:: PMC8179202

Abstract Article PDF–2.9M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80723304.

SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes

Yize Li, David M. Renner, Courtney E. Comar, Jillian N. Whelan, Hanako M. Reyes, Fabian Leonardo Cardenas-Diaz, Rachel Truitt, Li Hui Tan, Beihua Dong, Konstantinos Dionysios Alysandratos, Jessie Huang, James N. Palmer, Nithin D. Adappa, Michael A. Kohanski, Darrell N. Kotton, Robert H. Silverman, Wenli Yang, Edward E. Morrisey, Noam A. Cohen, Susan R. Weiss

Proc Natl Acad Sci U S A. 2021 Apr 20; 118(16): e2022643118. Published online 2021 Apr 2. doi: 10.1073/pnas.2022643118

Correction in:: Proc Natl Acad Sci U S A. 2023 Jul 18; 120(29): e2310153120.

PMCID:: PMC8072330

Abstract Article PDF–1.9M

Select item 79221755.

ABCE1 Regulates RNase L-Induced Autophagy during Viral Infections

Barkha Ramnani, Praveen Manivannan, Sarah Jaggernauth, Krishnamurthy Malathi

Viruses. 2021 Feb; 13(2): 315. Published online 2021 Feb 18. doi: 10.3390/v13020315

PMCID:: PMC7922175

Abstract Article PDF–1.6M

Select item 74273276.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 70083617.

RNase L promotes the formation of unique ribonucleoprotein granules distinct from stress granules

James M. Burke, Evan T. Lester, Devin Tauber, Roy Parker

J Biol Chem. 2020 Feb 7; 295(6): 1426–1438. Published online 2020 Jan 2. doi: 10.1074/jbc.RA119.011638

PMCID:: PMC7008361

Abstract Article PDF–5.1M

Select item 68574278.

Evidence from 40 Studies that 2 Common Single-Nucleotide Polymorphisms (SNPs) of RNASEL Gene Affect Prostate Cancer Susceptibility: A Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)-Compliant Meta-Analysis

Jun Xia, Rulin Sun

Med Sci Monit. 2019; 25: 8315–8325. Published online 2019 Nov 5. doi: 10.12659/MSM.917715

PMCID:: PMC6857427

Abstract Article PDF–1.5M

Select item 67358529.

The role of ZAP and OAS3/RNAseL pathways in the attenuation of an RNA virus with elevated frequencies of CpG and UpA dinucleotides

Valerie Odon, Jelke J Fros, Niluka Goonawardane, Isabelle Dietrich, Ahmad Ibrahim, Kinda Alshaikhahmed, Dung Nguyen, Peter Simmonds

Nucleic Acids Res. 2019 Sep 5; 47(15): 8061–8083. Published online 2019 Jul 5. doi: 10.1093/nar/gkz581

PMCID:: PMC6735852

Abstract Article PDF–16M

Select item 582692610.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 580631611.

Is RNASEL:p.Glu265* a modifier of early-onset breast cancer risk for carriers of high-risk mutations?

Tú Nguyen-Dumont, Zhi L. Teo, Fleur Hammet, Alexis Roberge, Maryam Mahmoodi, Helen Tsimiklis, Daniel J. Park, Bernard J. Pope, Andrew Lonie, Miroslav K. Kapuscinski, Khalid Mahmood, ABCFR, David E. Goldgar, Graham G. Giles, Ingrid Winship, John L. Hopper, Melissa C. Southey

BMC Cancer. 2018; 18: 165. Published online 2018 Feb 8. doi: 10.1186/s12885-018-4028-z

PMCID:: PMC5806316

Abstract Article PDF–615K

Select item 564803412.

Rapid RNase L–driven arrest of protein synthesis in the dsRNA response without degradation of translation machinery

Jesse Donovan, Sneha Rath, David Kolet-Mandrikov, Alexei Korennykh

RNA. 2017 Nov; 23(11): 1660–1671. doi: 10.1261/rna.062000.117

PMCID:: PMC5648034

Abstract Article PDF–11M

Select item 553161113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 550753414.

Rosario López-Rodríguez, Ángel Hernández-Bartolomé, María Jesús Borque, Yolanda Rodríguez-Muñoz, Samuel Martín-Vílchez, Luisa García-Buey, Leticia González-Moreno, Yolanda Real-Martínez, Paloma Muñoz de Rueda, Javier Salmerón, José Ramón Vidal-Castiñeira, Carlos López-Larrea, Luis Rodrigo, Ricardo Moreno-Otero, Paloma Sanz-Cameno

PLoS One. 2017; 12(7): e0180927. Published online 2017 Jul 12. doi: 10.1371/journal.pone.0180927

PMCID:: PMC5507534

Abstract Article PDF–1.0M

Select item 540491215.

Ribonuclease L mediates the cell-lethal phenotype of double-stranded RNA editing enzyme ADAR1 deficiency in a human cell line

Yize Li, Shuvojit Banerjee, Stephen A Goldstein, Beihua Dong, Christina Gaughan, Sneha Rath, Jesse Donovan, Alexei Korennykh, Robert H Silverman, Susan R Weiss

eLife. 2017; 6: e25687. Published online 2017 Mar 31. doi: 10.7554/eLife.25687

PMCID:: PMC5404912

Abstract Article PDF–6.4M

Select item 539469316.

Mitochondrial C11orf83 is a potent Antiviral Protein Independent of interferon production

Yun Yang, Shaoquan Xiong, Bei Cai, Hui Luo, E. Dong, Qiqi Li, Gaili Ji, Chengjian Zhao, Yanjun Wen, Yuquan Wei, Hanshuo Yang

Sci Rep. 2017; 7: 44303. Published online 2017 Apr 18. doi: 10.1038/srep44303

PMCID:: PMC5394693

Abstract Article PDF–1.7M

Select item 538730017.

Human serum RNase-L level is inversely associated with metabolic syndrome and age

Yi-Ting Wang, Ping-Huei Tseng, Chi-Ling Chen, Der-Sheng Han, Yu-Chiao Chi, Fen-Yu Tseng, Wei-Shiung Yang

Cardiovasc Diabetol. 2017; 16: 46. Published online 2017 Apr 11. doi: 10.1186/s12933-017-0522-x

PMCID:: PMC5387300

Abstract Article PDF–1.0M

Select item 537254518.

RNase L Suppresses Androgen Receptor Signaling, Cell Migration and Matrix Metalloproteinase Activity in Prostate Cancer Cells

Shubham Dayal, Jun Zhou, Praveen Manivannan, Mohammad Adnan Siddiqui, Omaima Farid Ahmad, Matthew Clark, Sahezeel Awadia, Rafael Garcia-Mata, Lirim Shemshedini, Krishnamurthy Malathi

Int J Mol Sci. 2017 Mar; 18(3): 529. Published online 2017 Mar 1. doi: 10.3390/ijms18030529

PMCID:: PMC5372545

Abstract Article PDF–7.6M

Select item 503473019.

Single and Multivariate Associations of MSR1, ELAC2, and RNASEL with Prostate Cancer in an Ethnic Diverse Cohort of Men

Joke Beuten, Jonathan A.L. Gelfond, Jennifer L. Franke, Stacey Shook, Teresa L. Johnson-Pais, Ian M. Thompson, Robin J. Leach

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2016 Sep 23.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2010 Feb; 19(2): 588–599. Published online 2010 Jan 19. doi: 10.1158/1055-9965.EPI-09-0864

PMCID:: PMC5034730

Abstract Article PDF–407K

Select item 484162420.

Key genes involved in the immune response are generally not associated with intraprostatic inflammation in men without a prostate cancer diagnosis: Results from the Prostate Cancer Prevention Trial

Danyelle A. Winchester, Bora Gurel, Cathee Till, Phyllis J. Goodman, Catherine M. Tangen, Regina M. Santella, Teresa L. Johnson-Pais, Robin J. Leach, Ian M. Thompson, Jianfeng Xu, S. Lilly Zheng, M. Scott Lucia, Scott M. Lippmann, Howard L. Parnes, William B. Isaacs, Charles G. Drake, Angelo M. De Marzo, Elizabeth A. Platz

Prostate. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Prostate. 2016 May; 76(6): 565–574. Published online 2016 Jan 15. doi: 10.1002/pros.23147

PMCID:: PMC4841624

Abstract Article PDF–284K

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