PMC Links for GEO Profiles (Select 79324520) - PMC

Select item 83529641.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 55316113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 52609394.

Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease

Felipe Roberti Teixeira, Suzanne J. Randle, Shachi P. Patel, Tycho E.T. Mevissen, Grasilda Zenkeviciute, Tie Koide, David Komander, Heike Laman

Biochem J. 2016 Oct 15; 473(20): 3563–3580. Prepublished online 2016 Aug 8. Published online 2016 Oct 11. doi: 10.1042/BCJ20160387

PMCID:: PMC5260939

Abstract Article PDF–1.1M

Select item 50133155.

Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family

Xu Li, Kim My Tran, Kathryn E. Aziz, Alexey V. Sorokin, Junjie Chen, Wenqi Wang

Mol Cell Proteomics. 2016 Sep; 15(9): 3030–3044. Published online 2016 Jul 18. doi: 10.1074/mcp.M116.060277

PMCID:: PMC5013315

Abstract Article PDF–3.2M

Select item 48133156.

Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology

Cuilin Zhang, Zhun Shi, Lingzhi Zhang, Zehua Zhou, Xiaoyuan Zheng, Guiying Liu, Guojun Bu, Paul E. Fraser, Huaxi Xu, Yun-wu Zhang

J Cell Sci. 2016 Mar 1; 129(5): 994–1002. doi: 10.1242/jcs.176792

PMCID:: PMC4813315

Abstract Article

Select item 46671307.

Intra-mitochondrial Methylation Deficiency Due to Mutations in SLC25A26

Yoshihito Kishita, Aleksandra Pajak, Nikhita Ajit Bolar, Carlo M.T. Marobbio, Camilla Maffezzini, Daniela V. Miniero, Magnus Monné, Masakazu Kohda, Henrik Stranneheim, Kei Murayama, Karin Naess, Nicole Lesko, Helene Bruhn, Arnaud Mourier, Rolf Wibom, Inger Nennesmo, Ann Jespers, Paul Govaert, Akira Ohtake, Lut Van Laer, Bart L. Loeys, Christoph Freyer, Ferdinando Palmieri, Anna Wredenberg, Yasushi Okazaki, Anna Wedell

Am J Hum Genet. 2015 Nov 5; 97(5): 761–768. Published online 2015 Oct 29. doi: 10.1016/j.ajhg.2015.09.013

PMCID:: PMC4667130

Abstract Article PDF–1.3M

Select item 46172118.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 38937839.

Identification of proteins that interact with alpha A-crystallin using a human proteome microarray

Qi Fan, Lv-Zhen Huang, Xiang-Jia Zhu, Ke-Ke Zhang, Hong-Fei Ye, Yi Luo, Xing-Huai Sun, Peng Zhou, Yi Lu

Mol Vis. 2014; 20: 117–124. Published online 2014 Jan 14.

PMCID:: PMC3893783

Abstract Article PDF–1024K

Select item 338606910.

Functional genomics identifies therapeutic targets for MYC-driven cancer

Masafumi Toyoshima, Heather L. Howie, Maki Imakura, Ryan M. Walsh, James E. Annis, Aaron N. Chang, Jason Frazier, B. Nelson Chau, Andrey Loboda, Peter S. Linsley, Michele A. Cleary, Julie R. Park, Carla Grandori

Proc Natl Acad Sci U S A. 2012 Jun 12; 109(24): 9545–9550. Published online 2012 May 23. doi: 10.1073/pnas.1121119109

PMCID:: PMC3386069

Abstract Article PDF–940K

Select item 333819511.

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

Nona Sotoodehnia, Aaron Isaacs, Paul I.W. de Bakker, Marcus Dörr, Christopher Newton-Cheh, Ilja M. Nolte, Pim van der Harst, Martina Müller, Mark Eijgelsheim, Alvaro Alonso, Andrew A. Hicks, Sandosh Padmanabhan, Caroline Hayward, Albert Vernon Smith, Ozren Polasek, Steven Giovannone, Jingyuan Fu, Jared W. Magnani, Kristin D. Marciante, Arne Pfeufer, Sina A. Gharib, Alexander Teumer, Man Li, Joshua C. Bis, Fernando Rivadeneira, Thor Aspelund, Anna Köttgen, Toby Johnson, Kenneth Rice, Mark P.S. Sie, Amanda Ying Wang, Norman Klopp, Christian Fuchsberger, Sarah H. Wild, Irene Mateo Leach, Karol Estrada, Uwe Völker, Alan F. Wright, Folkert W. Asselbergs, Jiaxiang Qu, Aravinda Chakravarti, Moritz F. Sinner, Jan A. Kors, Astrid Petersmann, Tamara B. Harris, Elsayed Z. Soliman, Patricia B. Munroe, Bruce M. Psaty, Ben A. Oostra, L. Adrienne Cupples, Siegfried Perz, Rudolf A. de Boer, André G. Uitterlinden, Henry Vözke, Timothy D. Spector, Fang-Yu Liu, Eric Boerwinkle, Anna F. Dominiczak, Jerome I. Rotter, Gé van Herpen, Daniel Levy, H.-Erich Wichmann, Wiek H. van Gilst, Jacqueline C.M. Witteman, Heyo K. Kroemer, W.H. Linda Kao, Susan R. Heckbert, Thomas Meitinger, Albert Hofman, Harry Campbell, Aaron R. Folsom, Dirk J. van Veldhuisen, Christine Schwienbacher, Christopher J. O’Donnell, Claudia Beu Volpato, Mark J. Caulfield, John M. Connell, Lenore Launer, Xiaowen Lu, Lude Franke, Rudolf S.N. Fehrmann, Gerard te Meerman, Harry J.M. Groen, Rinse K. Weersma, Leonard H. van den Berg, Cisca Wijmenga, Roel A. Ophoff, Gerjan Navis, Igor Rudan, Harold Snieder, James F. Wilson, Peter P. Pramstaller, David S. Siscovick, Thomas J. Wang, Vilmundur Gudnason, Cornelia M. van Duijn, Stephan B. Felix, Glenn I. Fishman, Yalda Jamshidi, Bruno H Ch Stricker, Nilesh J. Samani, Stefan Kääb, Dan E. Arking

Nat Genet. Author manuscript; available in PMC 2012 Apr 27.

Published in final edited form as: Nat Genet. 2010 Dec; 42(12): 1068–1076. Published online 2010 Nov 14. doi: 10.1038/ng.716

PMCID:: PMC3338195

Abstract Article PDF–951K

Select item 317805912.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 294347613.

Genetic Variants in Nuclear-Encoded Mitochondrial Genes Influence AIDS Progression

Sher L. Hendrickson, James A. Lautenberger, Leslie Wei Chinn, Michael Malasky, Efe Sezgin, Lawrence A. Kingsley, James J. Goedert, Gregory D. Kirk, Edward D. Gomperts, Susan P. Buchbinder, Jennifer L. Troyer, Stephen J. O'Brien

PLoS One. 2010; 5(9): e12862. Published online 2010 Sep 21. doi: 10.1371/journal.pone.0012862

PMCID:: PMC2943476

Abstract Article PDF–461K

Select item 135612914.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

Select item 122404215.

Identification of the human mitochondrial S-adenosylmethionine transporter: bacterial expression, reconstitution, functional characterization and tissue distribution.

G Agrimi, M A Di Noia, C M T Marobbio, G Fiermonte, F M Lasorsa, F Palmieri

Biochem J. 2004 Apr 1; 379(Pt 1): 183–190. doi: 10.1042/BJ20031664

PMCID:: PMC1224042

Summary PDF–187K

Select item 13924116.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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