PMC Links for GEO Profiles (Select 79668090) - PMC

Select item 88731191.

Inhibitory effects on L- and N-type calcium channels by a novel Ca_Vβ₁ variant identified in a patient with autism spectrum disorder

Patrick Despang, Sarah Salamon, Alexandra Breitenkamp, Elza Kuzmenkina, Jan Matthes

Naunyn Schmiedebergs Arch Pharmacol. 2022; 395(4): 459–470. Published online 2022 Feb 5. doi: 10.1007/s00210-022-02213-7

PMCID:: PMC8873119

Abstract Article PDF–2.1M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 71699833.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 63350144.

Functional and structural characterization of a novel malignant hyperthermia-susceptible variant of DHPR-β_1a subunit (CACNB1)

Claudio F. Perez, Jose M. Eltit, Jose R. Lopez, Dóra Bodnár, Angela F. Dulhunty, Shouvik Aditya, Marco G. Casarotto

Am J Physiol Cell Physiol. 2018 Mar 1; 314(3): C323–C333. Published online 2017 Dec 6. doi: 10.1152/ajpcell.00187.2017

PMCID:: PMC6335014

Abstract Article

Select item 55316115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 50430476.

Voltage‐gated calcium channels and their auxiliary subunits: physiology and pathophysiology and pharmacology

Annette C. Dolphin

J Physiol. 2016 Oct 1; 594(19): 5369–5390. Published online 2016 Jul 5. doi: 10.1113/JP272262

PMCID:: PMC5043047

Abstract Article PDF–940K

Select item 49194587.

Fluorescence Resonance Energy Transfer-based Structural Analysis of the Dihydropyridine Receptor α_1S Subunit Reveals Conformational Differences Induced by Binding of the β_1a Subunit

Mohana Mahalingam, Claudio F. Perez, James D. Fessenden

J Biol Chem. 2016 Jun 24; 291(26): 13762–13770. Published online 2016 Apr 25. doi: 10.1074/jbc.M115.704049

PMCID:: PMC4919458

Abstract Article PDF–1.4M

Select item 43678578.

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing

Fernanda Luisa Basei, Gabriela Vaz Meirelles, Germanna Lima Righetto, Deivid Lucas dos Santos Migueleti, Juliana Helena Costa Smetana, Jörg Kobarg

Proteome Sci. 2015; 13: 11. Published online 2015 Feb 26. doi: 10.1186/s12953-015-0065-6

PMCID:: PMC4367857

Abstract Article PDF–3.1M

Select item 36150309.

Ca_V1.1: The atypical prototypical voltage-gated Ca²⁺ channel

Roger A. Bannister, Kurt G. Beam

Biochim Biophys Acta. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: Biochim Biophys Acta. 2013 Jul; 1828(7): 1587–1597. Published online 2012 Sep 13. doi: 10.1016/j.bbamem.2012.09.007

PMCID:: PMC3615030

Abstract Article PDF–1.3M

Select item 356108410.

Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers

Gordan Lauc, Jennifer E. Huffman, Maja Pučić, Lina Zgaga, Barbara Adamczyk, Ana Mužinić, Mislav Novokmet, Ozren Polašek, Olga Gornik, Jasminka Krištić, Toma Keser, Veronique Vitart, Blanca Scheijen, Hae-Won Uh, Mariam Molokhia, Alan Leslie Patrick, Paul McKeigue, Ivana Kolčić, Ivan Krešimir Lukić, Olivia Swann, Frank N. van Leeuwen, L. Renee Ruhaak, Jeanine J. Houwing-Duistermaat, P. Eline Slagboom, Marian Beekman, Anton J. M. de Craen, André M. Deelder, Qiang Zeng, Wei Wang, Nicholas D. Hastie, Ulf Gyllensten, James F. Wilson, Manfred Wuhrer, Alan F. Wright, Pauline M. Rudd, Caroline Hayward, Yurii Aulchenko, Harry Campbell, Igor Rudan

PLoS Genet. 2013 Jan; 9(1): e1003225. Published online 2013 Jan 31. doi: 10.1371/journal.pgen.1003225

PMCID:: PMC3561084

Abstract Article PDF–1.0M

Select item 337273811.

A β-amyloid oligomer directly modulates P/Q-type calcium currents in Xenopus oocytes

M Mezler, S Barghorn, H Schoemaker, G Gross, V Nimmrich

Br J Pharmacol. 2012 Mar; 165(5): 1572–1583. doi: 10.1111/j.1476-5381.2011.01646.x

PMCID:: PMC3372738

Abstract Article PDF–995K

Select item 319082612.

Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN

Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi

J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907

PMCID:: PMC3190826

Abstract Article PDF–5.7M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 282448814.

Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays

Avinash Persaud, Philipp Alberts, Eva M Amsen, Xuejian Xiong, James Wasmuth, Zachary Saadon, Chris Fladd, John Parkinson, Daniela Rotin

Mol Syst Biol. 2009; 5: 333. Published online 2009 Dec 1. doi: 10.1038/msb.2009.85

PMCID:: PMC2824488

Abstract Article PDF–3.1M

Select item 226917615.

Differential plasma membrane targeting of voltage-dependent calcium channel subunits expressed in a polarized epithelial cell line

Nicola L Brice, Annette C Dolphin

J Physiol. 1999 Mar 15; 515(Pt 3): 685–694. doi: 10.1111/j.1469-7793.1999.685ab.x

PMCID:: PMC2269176

Abstract Article PDF–3.6M

Select item 193441216.

Structure–function studies of the G-domain from human gem, a novel small G-protein

Yarden Opatowsky, Yehezkel Sasson, Isabella Shaked, Yvona Ward, Orna Chomsky-Hecht, Yael Litvak, Zvi Selinger, Kathleen Kelly, Joel A. Hirsch

FEBS Lett. Author manuscript; available in PMC 2007 Jul 30.

Published in final edited form as: FEBS Lett. 2006 Oct 30; 580(25): 5959–5964. Published online 2006 Oct 6. doi: 10.1016/j.febslet.2006.09.067

PMCID:: PMC1934412

Abstract Article PDF–929K

Select item 51531617.

Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions

Yutaka Suzuki, Riu Yamashita, Matsuyuki Shirota, Yuta Sakakibara, Joe Chiba, Junko Mizushima-Sugano, Kenta Nakai, Sumio Sugano

Genome Res. 2004 Sep; 14(9): 1711–1718. doi: 10.1101/gr.2435604

PMCID:: PMC515316

Abstract Article PDF–181K

Select item 28361518.

Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPases

Brian S. Finlin, Shawn M. Crump, Jonathan Satin, Douglas A. Andres

Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14469–14474. Published online 2003 Nov 17. doi: 10.1073/pnas.2437756100

PMCID:: PMC283615

Abstract Article PDF–454K

Select item 13924119.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

Select item 1947720.

Absence of the β subunit (cchb1) of the skeletal muscle dihydropyridine receptor alters expression of the α₁ subunit and eliminates excitation-contraction coupling

Ronald G. Gregg, Albee Messing, Caroline Strube, Maryline Beurg, Richard Moss, Mary Behan, Manana Sukhareva, Susan Haynes, Jeanne A. Powell, Roberto Coronado, Patricia A. Powers

Proc Natl Acad Sci U S A. 1996 Nov 26; 93(24): 13961–13966. doi: 10.1073/pnas.93.24.13961

PMCID:: PMC19477

Abstract Article PDF–630K

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