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Select item 100729061.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 100677512.

Abundance of ACVR1B transcript is elevated during septic conditions: Perspectives obtained from a hands-on reductionist investigation

Anucha Preechanukul, Thatcha Yimthin, Sarunporn Tandhavanant, Tobias Brummaier, Chalita Chomkatekaew, Sukanta Das, Basirudeen Syed Ahamed Kabeer, Mohammed Toufiq, Darawan Rinchai, T. Eoin West, Damien Chaussabel, Narisara Chantratita, Mathieu Garand

Front Immunol. 2023; 14: 1072732. Published online 2023 Mar 20. doi: 10.3389/fimmu.2023.1072732

PMCID:: PMC10067751

Abstract Article PDF–2.6M

Select item 97584293.

Activin receptor ALK4 promotes adipose tissue hyperplasia by suppressing differentiation of adipocyte precursors

Ee-Soo Lee, Tingqing Guo, Raj Kamal Srivastava, Assim Shabbir, Carlos F. Ibáñez

J Biol Chem. 2023 Jan; 299(1): 102716. Published online 2022 Nov 18. doi: 10.1016/j.jbc.2022.102716

PMCID:: PMC9758429

Abstract Article PDF–3.8M

Select item 94339384.

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB

Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan

EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698

PMCID:: PMC9433938

Abstract Article PDF–9.3M

Select item 90051875.

Lack of Tgfbr1 and Acvr1b synergistically stimulates myofibre hypertrophy and accelerates muscle regeneration

Michèle MG Hillege, Andi Shi, Ricardo A Galli, Gang Wu, Philippe Bertolino, Willem MH Hoogaars, Richard T Jaspers

eLife. 2022; 11: e77610. Published online 2022 Mar 24. doi: 10.7554/eLife.77610

PMCID:: PMC9005187

Abstract Article PDF–8.5M

Select item 89515566.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Abstract Article PDF–4.4M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78634308.

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation

Xiaoqing Fan, Haoran Yang, Chenggang Zhao, Lizhu Hu, Delong Wang, Ruiting Wang, Zhiyou Fang, Xueran Chen

Stem Cell Res Ther. 2021; 12: 107. Published online 2021 Feb 4. doi: 10.1186/s13287-021-02175-2

PMCID:: PMC7863430

Abstract Article PDF–6.5M

Select item 68894929.

Blockade of ALK4/5 signaling suppresses cadmium- and erastin-induced cell death in renal proximal tubular epithelial cells via distinct signaling mechanisms

Kota Fujiki, Hisako Inamura, Takeshi Sugaya, Masato Matsuoka

Cell Death Differ. 2019 Nov; 26(11): 2371–2385. Published online 2019 Feb 25. doi: 10.1038/s41418-019-0307-8

PMCID:: PMC6889492

Abstract Article PDF–2.4M

Select item 644462710.

Integrative Genomics Analysis Identifies ACVR1B as a Candidate Causal Gene of Emphysema Distribution

Adel Boueiz, Betty Pham, Robert Chase, Andrew Lamb, Sool Lee, Zun Zar Chi Naing, Michael H. Cho, Margaret M. Parker, Phuwanat Sakornsakolpat, Craig P. Hersh, James D. Crapo, Andrew B. Stergachis, Ruth Tal-Singer, Dawn L. DeMeo, Edwin K. Silverman, Xiaobo Zhou, , on behalf of Genetic Epidemiology of COPD (COPDGene) Investigators

Am J Respir Cell Mol Biol. 2019 Apr; 60(4): 388–398. doi: 10.1165/rcmb.2018-0110OC

PMCID:: PMC6444627

Abstract Article PDF–1.0M

Select item 641170111.

The Activin Receptor, Activin-Like Kinase 4, Mediates Toxoplasma Gondii Activation of Hypoxia Inducible Factor-1

Agnieszka Lis, Mandi Wiley, Joan Vaughan, Peter C. Gray, Ira J. Blader

Front Cell Infect Microbiol. 2019; 9: 36. Published online 2019 Mar 5. doi: 10.3389/fcimb.2019.00036

PMCID:: PMC6411701

Abstract Article PDF–2.7M

Select item 620139412.

Activin Receptor‐Like Kinase 4 Haplodeficiency Mitigates Arrhythmogenic Atrial Remodeling and Vulnerability to Atrial Fibrillation in Cardiac Pathological Hypertrophy

Qian Wang, Yihe Chen, Daoliang Zhang, Changyi Li, Xiaoqing Chen, Jianwen Hou, Yudong Fei, Yuepeng Wang, Yigang Li

J Am Heart Assoc. 2018 Aug 21; 7(16): e008842. Published online 2018 Aug 15. doi: 10.1161/JAHA.118.008842

PMCID:: PMC6201394

Abstract Article PDF–4.4M

Select item 553161113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 535451414.

Biochemical and Cellular Analysis Reveals Ligand Binding Specificities, a Molecular Basis for Ligand Recognition, and Membrane Association-dependent Activities of Cripto-1 and Cryptic

Senem Aykul, Anthony Parenti, Kit Yee Chu, Jake Reske, Monique Floer, Amy Ralston, Erik Martinez-Hackert

J Biol Chem. 2017 Mar 10; 292(10): 4138–4151. Published online 2017 Jan 26. doi: 10.1074/jbc.M116.747501

PMCID:: PMC5354514

Abstract Article PDF–3.1M

Select item 516151415.

New function of the myostatin/activin type I receptor (ALK4) as a mediator of muscle atrophy and muscle regeneration

Svitlana Pasteuning-Vuhman, Johanna W. Boertje-van der Meulen, Maaike van Putten, Maurice Overzier, Peter ten Dijke, Szymon M. Kiełbasa, Wibowo Arindrarto, Ron Wolterbeek, Ksenia V. Lezhnina, Ivan V. Ozerov, Aleksandr M. Aliper, Willem M. Hoogaars, Annemieke Aartsma-Rus, Cindy J. M. Loomans

FASEB J. 2017 Jan; 31(1): 238–255. Published online 2016 Oct 12. doi: 10.1096/fj.201600675R

PMCID:: PMC5161514

Abstract Article

Select item 497456016.

The Expression of Human Cytomegalovirus MicroRNA MiR-UL148D during Latent Infection in Primary Myeloid Cells Inhibits Activin A-triggered Secretion of IL-6

Betty Lau, Emma Poole, Benjamin Krishna, Immaculada Sellart, Mark R. Wills, Eain Murphy, John Sinclair

Sci Rep. 2016; 6: 31205. Published online 2016 Aug 5. doi: 10.1038/srep31205

Correction in:: Sci Rep. 2016; 6: 33771.

PMCID:: PMC4974560

Abstract Article PDF–1.5M

Select item 489079917.

ACVR1B rs2854464 Is Associated with Sprint/Power Athletic Status in a Large Cohort of Europeans but Not Brazilians

Sarah Voisin, João Paulo F. L. Guilherme, Xu Yan, Vladimir P. Pushkarev, Pawel Cieszczyk, Myosotis Massidda, Carla M. Calò, Dmitry A. Dyatlov, Vitaliy A. Kolupaev, Yuliya E. Pushkareva, Agnieszka Maciejewska, Marek Sawczuk, Antonio H. Lancha, Jr, Guilherme G. Artioli, Nir Eynon

PLoS One. 2016; 11(6): e0156316. Published online 2016 Jun 2. doi: 10.1371/journal.pone.0156316

PMCID:: PMC4890799

Abstract Article PDF–526K

Select item 481495818.

NODAL secreted by male germ cells regulates the proliferation and function of human Sertoli cells from obstructive azoospermia and nonobstructive azoospermia patients

Ru-Hui Tian, Shi Yang, Zi-Jue Zhu, Jun-Long Wang, Yun Liu, Chencheng Yao, Meng Ma, Ying Guo, Qingqing Yuan, Yanan Hai, Yi-Ran Huang, Zuping He, Zheng Li

Asian J Androl. 2015 Nov-Dec; 17(6): 996–1005. Published online 2015 Aug 19. doi: 10.4103/1008-682X.159722

PMCID:: PMC4814958

Abstract Article PDF–3.8M

Select item 461721119.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 453937220.

PU.1-Regulated Long Noncoding RNA lnc-MC Controls Human Monocyte/Macrophage Differentiation through Interaction with MicroRNA 199a-5p

Ming-Tai Chen, Hai-Shuang Lin, Chao Shen, Yan-Ni Ma, Fang Wang, Hua-Lu Zhao, Jia Yu, Jun-Wu Zhang

Mol Cell Biol. 2015 Sep; 35(18): 3212–3224. Prepublished online 2015 Jul 6. Published online 2015 Aug 17. doi: 10.1128/MCB.00429-15

PMCID:: PMC4539372

Abstract Article PDF–3.7M

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