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Select item 111481841.

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek

Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x

PMCID:: PMC11148184

Abstract Article PDF–8.1M

Select item 111094832.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 108910593.

Expression of the checkpoint kinase BUB1 is a predictor of response to cancer therapies

Ylenia Cicirò, Denise Ragusa, Arturo Sala

Sci Rep. 2024; 14: 4461. Published online 2024 Feb 23. doi: 10.1038/s41598-024-55080-y

PMCID:: PMC10891059

Abstract Article PDF–6.7M

Select item 103580264.

BUB1 Immunolocalization in Breast Carcinoma: Its Nuclear Localization as a Potent Prognostic Factor of the Patients

Kiyoshi Takagi, Yasuhiro Miki, Yukiko Shibahara, Yasuhiro Nakamura, Akiko Ebata, Mika Watanabe, Takanori Ishida, Hironobu Sasano, Takashi Suzuki

Horm Cancer. 2013 Apr; 4(2): 92–102. Published online 2013 Jan 4. doi: 10.1007/s12672-012-0130-x

PMCID:: PMC10358026

Abstract Article PDF–450K

Select item 100729065.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 95826296.

BubR1 recruitment to the kinetochore via Bub1 enhances spindle assembly checkpoint signaling

Anand Banerjee, Chu Chen, Lauren Humphrey, John J. Tyson, Ajit P. Joglekar

Mol Biol Cell. 2022 Sep 1; 33(10): br16. Published online 2022 Aug 18. doi: 10.1091/mbc.E22-03-0085

PMCID:: PMC9582629

Abstract Article PDF–4.0M

Select item 91197367.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 91063038.

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors

Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen

Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638

PMCID:: PMC9106303

Abstract Article PDF–918K

Select item 90537619.

BUBs Are New Biomarkers of Promoting Tumorigenesis and Affecting Prognosis in Breast Cancer

Shunan Wang, Xinyu Liu, Meng Yang, Dongqi Yuan, Kui Ye, Xin Qu, Xinchao Wang

Dis Markers. 2022; 2022: 2760432. Published online 2022 Apr 21. doi: 10.1155/2022/2760432

PMCID:: PMC9053761

Abstract Article PDF–2.4M

Select item 876954310.

Biallelic BUB1 mutations cause microcephaly, developmental delay, and variable effects on cohesion and chromosome segregation

Sara Carvalhal, Ingrid Bader, Martin A. Rooimans, Anneke B. Oostra, Jesper A. Balk, René G. Feichtinger, Christine Beichler, Michael R. Speicher, Johanna M. van Hagen, Quinten Waisfisz, Mieke van Haelst, Martijn Bruijn, Alexandra Tavares, Johannes A. Mayr, Rob M. F. Wolthuis, Raquel A. Oliveira, Job de Lange

Sci Adv. 2022 Jan; 8(3): eabk0114. Published online 2022 Jan 19. doi: 10.1126/sciadv.abk0114

PMCID:: PMC8769543

Abstract Article PDF–1.2M

Select item 876907211.

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584

PMCID:: PMC8769072

Abstract Article PDF–2.9M

Select item 876331712.

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation

Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley

Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h

PMCID:: PMC8763317

Abstract Article

Select item 865748313.

Prognostic Value of BUB1 for Predicting Non-Muscle-Invasive Bladder Cancer Progression

Xuan-Mei Piao, Chaelin You, Young Joon Byun, Ho Won Kang, Junho Noh, Jaehyun Lee, Hee Youn Lee, Kyeong Kim, Won Tae Kim, Seok Joong Yun, Sang-Cheol Lee, Kyuho Kang, Yong-June Kim

Int J Mol Sci. 2021 Dec; 22(23): 12756. Published online 2021 Nov 25. doi: 10.3390/ijms222312756

PMCID:: PMC8657483

Abstract Article PDF–1.6M

Select item 841916314.

Inhibition of BUB1 suppresses tumorigenesis of osteosarcoma via blocking of PI3K/Akt and ERK pathways

Zhen Huang, Shenglin Wang, Hongxiang Wei, Hui Chen, Rongkai Shen, Renqin Lin, Xinwen Wang, Wenbin Lan, Rongjin Lin, Jianhua Lin

J Cell Mol Med. 2021 Sep; 25(17): 8442–8453. Published online 2021 Aug 1. doi: 10.1111/jcmm.16805

PMCID:: PMC8419163

Abstract Article PDF–2.2M

Select item 839110415.

Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1

Elyse S Fischer, Conny W H Yu, Dom Bellini, Stephen H McLaughlin, Christian M Orr, Armin Wagner, Stefan M V Freund, David Barford

EMBO Rep. 2021 Jul 5; 22(7): e52242. Published online 2021 May 19. doi: 10.15252/embr.202052242

PMCID:: PMC8391104

Abstract Article PDF–3.1M

Select item 827460316.

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome

Jérémy A. Ferreira Barbosa, Samantha Sparapani, Jonathan Boulais, Robert Lodge, Éric A. Cohen

J Virol. 2021 Aug; 95(15): e00971-20. Prepublished online 2021 May 19. Published online 2021 Jul 12. doi: 10.1128/JVI.00971-20

PMCID:: PMC8274603

Abstract Article PDF–4.2M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 816047918.

KIF4A knockdown suppresses ovarian cancer cell proliferation and induces apoptosis by downregulating BUB1 expression

Wumin Jin, Lianmin Ye

Mol Med Rep. 2021 Jul; 24(1): 516. Published online 2021 May 17. doi: 10.3892/mmr.2021.12155

PMCID:: PMC8160479

Abstract Article PDF–11M

Select item 814848819.

Expression and prognosis analyses of BUB1, BUB1B and BUB3 in human sarcoma

Zeling Long, Tong Wu, Qunyan Tian, Luke A. Carlson, Wanchun Wang, Gen Wu

Aging (Albany NY) 2021 May 15; 13(9): 12395–12409. Published online 2021 Apr 19. doi: 10.18632/aging.202944

PMCID:: PMC8148488

Abstract Article PDF–2.0M

Select item 810850720.

Differential requirements for the CENP-O complex reveal parallel PLK1 kinetochore recruitment pathways

Alexandra L. Nguyen, Marie Diane Fadel, Iain M. Cheeseman

Mol Biol Cell. 2021 Apr 15; 32(8): 712–721. doi: 10.1091/mbc.E20-11-0751

PMCID:: PMC8108507

Abstract Article PDF–6.5M

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