PMC Links for GEO Profiles (Select 80012689) - PMC

Select item 93383131.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Abstract Article PDF–2.8M

Select item 88570492.

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

Tara E. Tracy, Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q. Trojanowski, Virginia M.Y. Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J. Krogan, Daniel H. Geschwind, Li Gan

Cell. Author manuscript; available in PMC 2022 Feb 19.

Published in final edited form as: Cell. 2022 Feb 17; 185(4): 712–728.e14. Published online 2022 Jan 20. doi: 10.1016/j.cell.2021.12.041

PMCID:: PMC8857049

Abstract Article PDF–3.6M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78853924.

Differentiation of two human neuroblastoma cell lines alters SV2 expression patterns

Emilia Lekholm, Mikaela M. Ceder, Erica C. Forsberg, Helgi B. Schiöth, Robert Fredriksson

Cell Mol Biol Lett. 2021; 26: 5. Published online 2021 Feb 15. doi: 10.1186/s11658-020-00243-8

PMCID:: PMC7885392

Abstract Article PDF–1.9M

Select item 71715845.

Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans: A Genome-Wide Association Study

Jia Nee Foo, Elaine Guo Yan Chew, Sun Ju Chung, Rong Peng, Cornelis Blauwendraat, Mike A. Nalls, Kin Y. Mok, Wataru Satake, Tatsushi Toda, Yinxia Chao, Louis C. S. Tan, Moses Tandiono, Michelle M. Lian, Ebonne Y. Ng, Kumar-M. Prakash, Wing-Lok Au, Wee-Yang Meah, Shi Qi Mok, Azlina Ahmad Annuar, Anne Y. Y. Chan, Ling Chen, Yongping Chen, Beom S. Jeon, Lulu Jiang, Jia Lun Lim, Juei-Jueng Lin, Chunfeng Liu, Chengjie Mao, Vincent Mok, Zhong Pei, Hui-Fang Shang, Chang-He Shi, Kyuyoung Song, Ai Huey Tan, Yih-Ru Wu, Yu-ming Xu, Renshi Xu, Yaping Yan, Jing Yang, BaoRong Zhang, Woon-Puay Koh, Shen-Yang Lim, Chiea Chuen Khor, Jianjun Liu, Eng-King Tan

JAMA Neurol. 2020 Apr 20 : e200428. doi: 10.1001/jamaneurol.2020.0428 [Epub ahead of print]

PMCID:: PMC7171584

Abstract Article

Select item 67928866.

SVOP, an Evolutionarily Conserved Synaptic Vesicle Protein, Suggests Novel Transport Functions of Synaptic Vesicles

Roger Janz, Kay Hofmann, Thomas C. Südhof

J Neurosci. 1998 Nov 15; 18(22): 9269–9281. doi: 10.1523/JNEUROSCI.18-22-09269.1998

PMCID:: PMC6792886

Abstract Article PDF–1.1M

Select item 55316117.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 53583628.

Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease

Amy R. Dunn, Kristen A. Stout, Minagi Ozawa, Kelly M. Lohr, Carlie A. Hoffman, Alison I. Bernstein, Yingjie Li, Minzheng Wang, Carmelo Sgobio, Namratha Sastry, Huaibin Cai, W. Michael Caudle, Gary W. Miller

Proc Natl Acad Sci U S A. 2017 Mar 14; 114(11): E2253–E2262. Published online 2017 Feb 28. doi: 10.1073/pnas.1616892114

PMCID:: PMC5358362

Abstract Article PDF–1.8M

Select item 50336459.

N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A

Guorui Yao, Sicai Zhang, Stefan Mahrhold, Kwok-ho Lam, Daniel Stern, Karine Bagramyan, Kay Perry, Markus Kalkum, Andreas Rummel, Min Dong, Rongsheng Jin

Nat Struct Mol Biol. Author manuscript; available in PMC 2016 Dec 13.

Published in final edited form as: Nat Struct Mol Biol. 2016 Jul; 23(7): 656–662. Published online 2016 Jun 13. doi: 10.1038/nsmb.3245

PMCID:: PMC5033645

Abstract Article PDF–1.7M

Select item 445385710.

Genetic variant predicts bevacizumab-induced hypertension in ECOG-5103 and ECOG-2100

B P Schneider, L Li, F Shen, K D Miller, M Radovich, A O'Neill, R J Gray, D Lane, D A Flockhart, G Jiang, Z Wang, D Lai, D Koller, J H Pratt, C T Dang, D Northfelt, E A Perez, T Shenkier, M Cobleigh, M L Smith, E Railey, A Partridge, J Gralow, J Sparano, N E Davidson, T Foroud, G W Sledge

Br J Cancer. 2014 Sep 9; 111(6): 1241–1248. Published online 2014 Aug 12. doi: 10.1038/bjc.2014.430

PMCID:: PMC4453857

Abstract Article PDF–1.0M

Select item 404112311.

Genome-wide meta-analysis identifies new susceptibility loci for migraine

Verneri Anttila, Bendik S. Winsvold, Padhraig Gormley, Tobias Kurth, Francesco Bettella, George McMahon, Mikko Kallela, Rainer Malik, Boukje de Vries, Gisela Terwindt, Sarah E. Medland, Unda Todt, Wendy L. McArdle, Lydia Quaye, Markku Koiranen, M. Arfan Ikram, Terho Lehtimäki, Anine H. Stam, Lannie Ligthart, Juho Wedenoja, Ian Dunham, Benjamin M. Neale, Priit Palta, Eija Hamalainen, Markus Schürks, Lynda M Rose, Julie E. Buring, Paul M. Ridker, Stacy Steinberg, Hreinn Stefansson, Finnbogi Jakobsson, Debbie A. Lawlor, David M. Evans, Susan M. Ring, Markus Färkkilä, Ville Artto, Mari A Kaunisto, Tobias Freilinger, Jean Schoenen, Rune R. Frants, Nadine Pelzer, Claudia M. Weller, Ronald Zielman, Andrew C. Heath, Pamela A.F. Madden, Grant W. Montgomery, Nicholas G. Martin, Guntram Borck, Hartmut Göbel, Axel Heinze, Katja Heinze-Kuhn, Frances M.K. Williams, Anna-Liisa Hartikainen, Anneli Pouta, Joyce van den Ende, Andre G. Uitterlinden, Albert Hofman, Najaf Amin, Jouke-Jan Hottenga, Jacqueline M. Vink, Kauko Heikkilä, Michael Alexander, Bertram Muller-Myhsok, Stefan Schreiber, Thomas Meitinger, Heinz Erich Wichmann, Arpo Aromaa, Johan G. Eriksson, Bryan Traynor, Daniah Trabzuni, North American Brain Expression Consortium, UK Brain Expression Consortium, Elizabeth Rossin, Kasper Lage, Suzanne B.R. Jacobs, J. Raphael Gibbs, Ewan Birney, Jaakko Kaprio, Brenda W. Penninx, Dorret I. Boomsma, Cornelia van Duijn, Olli Raitakari, Marjo-Riitta Jarvelin, John-Anker Zwart, Lynn Cherkas, David P. Strachan, Christian Kubisch, Michel D. Ferrari, Arn M.J.M. van den Maagdenberg, Martin Dichgans, Maija Wessman, George Davey Smith, Kari Stefansson, Mark J. Daly, Dale R. Nyholt, Daniel Chasman, Aarno Palotie

Nat Genet. Author manuscript; available in PMC 2014 Jun 2.

Published in final edited form as: Nat Genet. 2013 Aug; 45(8): 912–917. Published online 2013 Jun 23. doi: 10.1038/ng.2676

PMCID:: PMC4041123

Article PDF–571K

Select item 399040612.

A genome-wide association study for venous thromboembolism: the extended Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

Weihong Tang, Martina Teichert, Daniel I. Chasman, John A. Heit, Pierre-Emmanuel Morange, Guo Li, Nathan Pankratz, Frank W. Leebeek, Guillaume Paré, Mariza de Andrade, Christophe Tzourio, Bruce M. Psaty, Saonli Basu, Rikje Ruiter, Lynda Rose, Sebastian M. Armasu, Thomas Lumley, Susan R. Heckbert, André G. Uitterlinden, Mark Lathrop, Kenneth M. Rice, Mary Cushman, Albert Hofman, Jean-Charles Lambert, Nicole L. Glazer, James S. Pankow, Jacqueline C. Witteman, Philippe Amouyel, Joshua C. Bis, Edwin G. Bovill, Xiaoxiao Kong, Russell P. Tracy, Eric Boerwinkle, Jerome I. Rotter, David-Alexandre Trégouët, Daan W. Loth, Bruno H. Ch. Stricker, Paul M Ridker, Aaron R. Folsom, Nicholas L. Smith

Genet Epidemiol. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: Genet Epidemiol. 2013 Jul; 37(5): 512–521. Published online 2013 May 5. doi: 10.1002/gepi.21731

PMCID:: PMC3990406

Abstract Article PDF–441K

Select item 385466913.

Genome Wide Association Study (GWAS) of Chagas Cardiomyopathy in Trypanosoma cruzi Seropositive Subjects

Xutao Deng, Ester C. Sabino, Edecio Cunha-Neto, Antonio L. Ribeiro, Barbara Ianni, Charles Mady, Michael P. Busch, Mark Seielstad, the REDSII Chagas study group from the NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II), International Component

PLoS One. 2013; 8(11): e79629. Published online 2013 Nov 20. doi: 10.1371/journal.pone.0079629

PMCID:: PMC3854669

Abstract Article PDF–408K

Select item 384521814.

Genotypic variation in the SV2C gene impacts response to atypical antipsychotics the CATIE Study

Timothy L. Ramsey, Qian Liu, Bill W. Massey, Mark D. Brennan

Schizophr Res. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Schizophr Res. 2013 Sep; 149(0): 10.1016/j.schres.2013.07.008. Published online 2013 Jul 23. doi: 10.1016/j.schres.2013.07.008

PMCID:: PMC3845218

Abstract Article PDF–557K

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 289646416.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Abstract Article PDF–2.4M

Select item 135612917.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

Select item 52892818.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

Select item 13924119.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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