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Select item 103511371.

A functional mechanism for a non-coding variant near AGTR2 associated with risk for preterm birth

Li Wang, Robert M. Rossi, Xiaoting Chen, Jing Chen, Jilian Runyon, Mehak Chawla, Daniel Miller, Carmy Forney, Arthur Lynch, Xuzhe Zhang, Fansheng Kong, Bo Jacobsson, Leah C. Kottyan, Matthew T. Weirauch, Ge Zhang, Louis J. Muglia

BMC Med. 2023; 21: 258. Published online 2023 Jul 17. doi: 10.1186/s12916-023-02973-w

PMCID:: PMC10351137

Abstract Article PDF–1.6M

Select item 95784712.

Angiotensin II type 2 receptor prevents extracellular matrix accumulation in human peritoneal mesothelial cell by ameliorating lipid disorder via LOX‐1 suppression

Jing Liu, Bo Jin, Jian Lu, Yuan Feng, Nan Li, Cheng Wan, Qing-Yan Zhang, Chun-Ming Jiang

Ren Fail. 2022; 44(1): 1687–1697. Published online 2022 Oct 13. doi: 10.1080/0886022X.2022.2133729

PMCID:: PMC9578471

Abstract Article PDF–1.5M

Select item 93180513.

The Role of ACE, ACE2, and AGTR2 Polymorphisms in COVID-19 Severity and the Presence of COVID-19-Related Retinopathy

Kristina Jevnikar, Luka Lapajne, Daniel Petrovič, Andrej Meglič, Mateja Logar, Nataša Vidovič Valentinčič, Mojca Globočnik Petrovič, Ines Cilenšek, Polona Jaki Mekjavić

Genes (Basel) 2022 Jul; 13(7): 1111. Published online 2022 Jun 21. doi: 10.3390/genes13071111

PMCID:: PMC9318051

Abstract Article PDF–4.1M

Select item 90537704.

AT2R activation increases in vitro angiogenesis in pregnant human uterine artery endothelial cells

Jay S. Mishra, Dong-Bao Chen, Sathish Kumar

PLoS One. 2022; 17(4): e0267826. Published online 2022 Apr 29. doi: 10.1371/journal.pone.0267826

PMCID:: PMC9053770

Abstract Article PDF–2.9M

Select item 83841975.

Colon adenocarcinoma-derived cells possessing stem cell function can be modulated using renin-angiotensin system inhibitors

Matthew J. Munro, Lifeng Peng, Susrutha K. Wickremesekera, Swee T. Tan

PLoS One. 2021; 16(8): e0256280. Published online 2021 Aug 24. doi: 10.1371/journal.pone.0256280

PMCID:: PMC8384197

Abstract Article PDF–5.6M

Select item 82231276.

Variants in AGTR2 gene in Maya people with COVID-19

Armando Totomoch-Serra, Miriam Givisay Domínguez-Cruz, C. Manterola, Maria de Lourdes Muñoz

Gene. 2021 Aug 30; 795: 145794. Published online 2021 Jun 24. doi: 10.1016/j.gene.2021.145794

PMCID:: PMC8223127

Article PDF–368K

Select item 77803487.

Brain Angiotensin Type-1 and Type-2 Receptors in Physiological and Hypertensive Conditions: Focus on Neuroinflammation

Khalid Elsaafien, Annette D. de Kloet, Eric G. Krause, Colin Sumners

Curr Hypertens Rep. Author manuscript; available in PMC 2021 Jul 13.

Published in final edited form as: Curr Hypertens Rep. 2020 Jul 13; 22(7): 48. Published online 2020 Jul 13. doi: 10.1007/s11906-020-01062-0

PMCID:: PMC7780348

Abstract Article PDF–797K

Select item 77660858.

Functional Complexes of Angiotensin-Converting Enzyme 2 and Renin-Angiotensin System Receptors: Expression in Adult but Not Fetal Lung Tissue

Rafael Franco, Alejandro Lillo, Rafael Rivas-Santisteban, Ana I. Rodríguez-Pérez, Irene Reyes-Resina, José L. Labandeira-García, Gemma Navarro

Int J Mol Sci. 2020 Dec; 21(24): 9602. Published online 2020 Dec 16. doi: 10.3390/ijms21249602

PMCID:: PMC7766085

Abstract Article PDF–7.2M

Select item 74104999.

A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm

Michael R Garvin, Christiane Alvarez, J Izaak Miller, Erica T Prates, Angelica M Walker, B Kirtley Amos, Alan E Mast, Amy Justice, Bruce Aronow, Daniel Jacobson

eLife. 2020; 9: e59177. Published online 2020 Jul 7. doi: 10.7554/eLife.59177

PMCID:: PMC7410499

Abstract Article PDF–2.2M

Select item 736385510.

The discovery of a new antibody for BRIL-fused GPCR structure determination

Hikaru Miyagi, Hidetsugu Asada, Michihiko Suzuki, Yuichi Takahashi, Mai Yasunaga, Chiyo Suno, So Iwata, Jun-ichi Saito

Sci Rep. 2020; 10: 11669. Published online 2020 Jul 15. doi: 10.1038/s41598-020-68355-x

PMCID:: PMC7363855

Abstract Article PDF–2.2M

Select item 719823211.

Potential harmful effects of discontinuing ACE-inhibitors and ARBs in COVID-19 patients

Gian Paolo Rossi, Viola Sanga, Matthias Barton

eLife. 2020; 9: e57278. Published online 2020 Apr 6. doi: 10.7554/eLife.57278

PMCID:: PMC7198232

Abstract Article PDF–798K

Select item 716758812.

The pivotal link between ACE2 deficiency and SARS-CoV-2 infection

Paolo Verdecchia, Claudio Cavallini, Antonio Spanevello, Fabio Angeli

Eur J Intern Med. 2020 Jun; 76: 14–20. Published online 2020 Apr 20. doi: 10.1016/j.ejim.2020.04.037

PMCID:: PMC7167588

Abstract Article PDF–1.1M

Select item 653335713.

Prevention of lipopolysaccharide-induced CD11b⁺ immune cell infiltration in the kidney: role of AT₂ receptors

Sanket Patel, Isha Dhande, Elizabeth Alana Gray, Quaisar Ali, Tahir Hussain

Biosci Rep. 2019 May 31; 39(5): BSR20190429. Prepublished online 2019 May 9. Published online 2019 May 24. doi: 10.1042/BSR20190429

PMCID:: PMC6533357

Abstract Article PDF–1.1M

Select item 608345814.

Angiotensin II Triggers Peripheral Macrophage-to-Sensory Neuron Redox Crosstalk to Elicit Pain

Andrew J. Shepherd, Bryan A. Copits, Aaron D. Mickle, Páll Karlsson, Suraj Kadunganattil, Simon Haroutounian, Satya M. Tadinada, Annette D. de Kloet, Manouela V. Valtcheva, Lisa A. McIlvried, Tayler D. Sheahan, Sanjay Jain, Pradipta R. Ray, Yuriy M. Usachev, Gregory Dussor, Eric G. Krause, Theodore J. Price, Robert W. Gereau, IV, Durga P. Mohapatra

J Neurosci. 2018 Aug 8; 38(32): 7032–7057. doi: 10.1523/JNEUROSCI.3542-17.2018

PMCID:: PMC6083458

Abstract Article PDF–12M

Select item 584394115.

Blood pressure, arterial stiffness and endogenous lithium clearance in relation to AGTR1 A1166C and AGTR2 G1675A gene polymorphisms

Marcin Cwynar, Jerzy Gąsowski, Anna Głuszewska, Jarosław Królczyk, Henryk Bartoń, Agnieszka Słowik, Tomasz Grodzicki

J Renin Angiotensin Aldosterone Syst. 2016 Apr-Jun; 17(2): 1470320316655669. Published online 2016 Jun 1. doi: 10.1177/1470320316655669

PMCID:: PMC5843941

Abstract Article PDF–599K

Select item 564339116.

Angiotensin II type 2 receptor (AT2R) as a novel modulator of inflammation in rheumatoid arthritis synovium

Riccardo Terenzi, Mirko Manetti, Irene Rosa, Eloisa Romano, Felice Galluccio, Serena Guiducci, Lidia Ibba-Manneschi, Marco Matucci-Cerinic

Sci Rep. 2017; 7: 13293. Published online 2017 Oct 16. doi: 10.1038/s41598-017-13746-w

PMCID:: PMC5643391

Abstract Article PDF–6.2M

Select item 558670617.

Association between Angiotensin II Type 2 Receptor Gene A/C3123 Polymorphism and High-Density Lipoprotein Cholesterol with Hypertension in Asymptomatic Women

Kazuhiko Kotani, Naoki Sakane, Nobuyuki Taniguchi

Med Princ Pract. 2012 Dec; 22(1): 65–69. Published online 2012 Aug 3. doi: 10.1159/000339892

PMCID:: PMC5586706

Abstract Article PDF–127K

Select item 557964618.

Association and Interaction Effect of AGTR1 and AGTR2 Gene Polymorphisms with Dietary Pattern on Metabolic Risk Factors of Cardiovascular Disease in Malaysian Adults

Roseline Wai Kuan Yap, Yoshihiro Shidoji, Wai Sum Yap, Motofumi Masaki

Nutrients. 2017 Aug; 9(8): 853. Published online 2017 Aug 9. doi: 10.3390/nu9080853

PMCID:: PMC5579646

Abstract Article PDF–258K

Select item 556142219.

Genetic Associations with Gestational Length and Spontaneous Preterm Birth

Ge Zhang, Bjarke Feenstra, Jonas Bacelis, Xueping Liu, Lisa M. Muglia, Julius Juodakis, Daniel E. Miller, Nadia Litterman, Pan-Pan Jiang, Laura Russell, David A. Hinds, Youna Hu, Matthew T. Weirauch, Xiaoting Chen, Arun R. Chavan, Günter P. Wagner, Mihaela Pavličev, Mauris C. Nnamani, Jamie Maziarz, Minna K. Karjalainen, Mika Rämet, Verena Sengpiel, D Frank Geller, Heather A. Boyd, Aarno Palotie, Allison Momany, Bruce Bedell, Kelli K. Ryckman, Johanna M. Huusko, Carmy R. Forney, Leah C. Kottyan, Mikko Hallman, Kari Teramo, Ellen A. Nohr, George Davey-Smith, Mads Melbye, Bo Jacobsson, Louis J. Muglia

N Engl J Med. Author manuscript;

Published in final edited form as: N Engl J Med. 2017 Sep 6; 377(12): 1156–1167. Published online 2017 Sep 6. doi: 10.1056/NEJMoa1612665

PMCID:: PMC5561422

Abstract Article PDF–1.9M

Select item 552554520.

Structural Basis for Selectivity and Diversity in Angiotensin II Receptors

Haitao Zhang, Gye Won Han, Alexander Batyuk, Andrii Ishchenko, Kate L. White, Nilkanth Patel, Anastasiia Sadybekov, Beata Zamlynny, Michael T. Rudd, Kaspar Hollenstein, Alexandra Tolstikova, Thomas A. White, Mark S. Hunter, Uwe Weierstall, Wei Liu, Kerim Babaoglu, Eric L. Moore, Ryan D. Katz, Jennifer M. Shipman, Margarita Garcia-Calvo, Sujata Sharma, Payal Sheth, Stephen M. Soisson, Raymond C. Stevens, Vsevolod Katritch, Vadim Cherezov

Nature. Author manuscript; available in PMC 2017 Oct 5.

Published in final edited form as: Nature. 2017 Apr 20; 544(7650): 327–332. Published online 2017 Apr 5. doi: 10.1038/nature22035

PMCID:: PMC5525545

Abstract Article PDF–4.2M

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