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Items: 1 to 20 of 577

1.
AIM2 inflammasome regulated by the IFN‐γ/JAK2/STAT1 pathway promotes activation and pyroptosis of monocytes in Coronary Artery Disease
Yue Zhao, Bin Liang, Shuyang Sheng, Chen Wang, Bingyu Jin, Xiaokang Zhang, Yating Cheng, Changxin Shen, Fang Zheng
Immun Inflamm Dis. 2024 Jun; 12(6): e1317. Published online 2024 Jun 13. doi: 10.1002/iid3.1317
PMCID:
PMC11170685
AbstractArticlePDF–3.7M
2.
Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma
Fei Xiong, Da Wang, Wei Xiong, Xin Wang, Wen-hua Huang, Guan-hua Wu, Wen-zheng Liu, Qi Wang, Jun-sheng Chen, Yi-yang Kuai, Bing Wang, Yong-jun Chen
J Exp Clin Cancer Res. 2024; 43: 152. Published online 2024 May 30. doi: 10.1186/s13046-024-03070-3
Correction in:
J Exp Clin Cancer Res. 2024; 43: 186.
PMCID:
PMC11137995
AbstractArticlePDF–20M
3.
CCT6A facilitates lung adenocarcinoma progression and glycolysis via STAT1/HK2 axis
Shao-Kun Yu, Tao Yu, Yu-Ming Wang, Ao Sun, Jia Liu, Kai-Hua Lu
J Transl Med. 2024; 22: 460. Published online 2024 May 15. doi: 10.1186/s12967-024-05284-7
PMCID:
PMC11094951
AbstractArticlePDF–4.6M
4.
USP39 Promotes the Viability and Migration of Head and Neck Squamous Cell Carcinoma Cell by Regulating STAT1
Yu Hu, Yang Wang, Wenrui Hu, Chenrui Hu, Bin Wang, Congli Liu, Anqi Deng, Bing Shen, Kaile Wu, Yehai Liu
Technol Cancer Res Treat. 2024; 23: 15330338241250298. Published online 2024 May 5. doi: 10.1177/15330338241250298
PMCID:
PMC11072062
AbstractArticlePDF–1.9M
5.
Reciprocal inhibition between TP63 and STAT1 regulates anti-tumor immune response through interferon-γ signaling in squamous cancer
Yuan Jiang, Yueyuan Zheng, Yuan-Wei Zhang, Shuai Kong, Jinxiu Dong, Fei Wang, Benjamin Ziman, Sigal Gery, Jia-Jie Hao, Dan Zhou, Jianian Zhou, Allen S. Ho, Uttam K. Sinha, Jian Chen, Shuo Zhang, Chuntong Yin, Dan-Dan Wei, Masaharu Hazawa, Huaguang Pan, Zhihao Lu, Wen-Qiang Wei, Ming-Rong Wang, H. Phillip Koeffler, De-Chen Lin, Yan-Yi Jiang
Nat Commun. 2024; 15: 2484. Published online 2024 Mar 20. doi: 10.1038/s41467-024-46785-9
PMCID:
PMC10954759
AbstractArticlePDF–8.0M
6.
HKDC1 promotes tumor immune evasion in hepatocellular carcinoma by coupling cytoskeleton to STAT1 activation and PD-L1 expression
Yi Zhang, Mingjie Wang, Ling Ye, Shengqi Shen, Yuxi Zhang, Xiaoyu Qian, Tong Zhang, Mengqiu Yuan, Zijian Ye, Jin Cai, Xiang Meng, Shiqiao Qiu, Shengzhi Liu, Rui Liu, Weidong Jia, Xianzhu Yang, Huafeng Zhang, Xiuying Zhong, Ping Gao
Nat Commun. 2024; 15: 1314. Published online 2024 Feb 13. doi: 10.1038/s41467-024-45712-2
PMCID:
PMC10864387
AbstractArticlePDF–5.6M
7.
AIM2 promotes irradiation resistance, migration ability and PD-L1 expression through STAT1/NF-κB activation in oral squamous cell carcinoma
Hui-Wen Chiu, Hsin-Lun Lee, Hsun-Hua Lee, Hsiao-Wei Lu, Kent Yu-Hsien Lin, Yuan-Feng Lin, Che-Hsuan Lin
J Transl Med. 2024; 22: 13. Published online 2024 Jan 3. doi: 10.1186/s12967-023-04825-w
PMCID:
PMC10762966
AbstractArticlePDF–9.1M
8.
ISGF3 and STAT2/IRF9 Control Basal and IFN-Induced Transcription through Genome-Wide Binding of Phosphorylated and Unphosphorylated Complexes to Common ISRE-Containing ISGs
Hanna Nowicka, Agata Sekrecka, Katarzyna Blaszczyk, Katarzyna Kluzek, Chan-Yu Chang, Joanna Wesoly, Chien-Kuo Lee, Hans A. R. Bluyssen
Int J Mol Sci. 2023 Dec; 24(24): 17635. Published online 2023 Dec 18. doi: 10.3390/ijms242417635
PMCID:
PMC10743977
AbstractArticlePDF–8.9M
9.
ESCO2 promotes hypopharyngeal carcinoma progression in a STAT1-dependent manner
Juan Hu, Jing Yan, Yijie Chen, Xiaohui Li, Liu Yang, Haiyu Di, Huihui Zhang, Yewen Shi, Junjie Zhao, Yanxia Shi, Yinglong Xu, Xiaoyong Ren, Zhenghui Wang
BMC Cancer. 2023; 23: 1114. Published online 2023 Nov 15. doi: 10.1186/s12885-023-11527-5
PMCID:
PMC10647066
AbstractArticlePDF–3.9M
10.
Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis
Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley
J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295
PMCID:
PMC10641524
AbstractArticlePDF–3.8M
11.
STAT1 deficiency underlies a proinflammatory imprint of naive CD4+ T cells in spondyloarthritis
Bilade Cherqaoui, Frédéric Crémazy, Marc Lauraine, Ghazal Shammas, Roula Said-Nahal, Hendrick Mambu Mambueni, Félicie Costantino, Marine Fourmont, Audrey Hulot, Henri-Jean Garchon, Simon Glatigny, Luiza M. Araujo, Maxime Breban
Front Immunol. 2023; 14: 1227281. Published online 2023 Oct 18. doi: 10.3389/fimmu.2023.1227281
PMCID:
PMC10619905
AbstractArticlePDF–7.0M
12.
The Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Breast Cancer Are Regulated by N-Linked Glycosylation-Dependent Activation of STAT3 and STAT1
Nofar Erlichman, Tsipi Meshel, Tamir Baram, Alaa Abu Raiya, Tamar Horvitz, Hagar Ben-Yaakov, Adit Ben-Baruch
Cells. 2023 Oct; 12(19): 2338. Published online 2023 Sep 23. doi: 10.3390/cells12192338
PMCID:
PMC10571791
AbstractArticlePDF–9.3M
13.
STAT1 overexpression triggers aplastic anemia: a pilot study unravelling novel pathogenetic insights in bone marrow failure
Antonio Giovanni Solimando, Vanessa Desantis, Carmen Palumbo, Carolina Marasco, Fabrizio Pappagallo, Monica Montagnani, Giuseppe Ingravallo, Sebastiano Cicco, Rosa Di Paola, Paula Tabares, Andreas Beilhack, Franco Dammacco, Roberto Ria, Angelo Vacca
Clin Exp Med. 2023; 23(6): 2687–2694. Published online 2023 Feb 24. doi: 10.1007/s10238-023-01017-0
PMCID:
PMC10543574
AbstractArticlePDF–1.0M
14.
Neutrophils in STAT1 Gain-Of-Function Have a Pro-inflammatory Signature Which Is Not Rescued by JAK Inhibition
Zuzana Parackova, Petra Vrabcova, Irena Zentsova, Anna Sediva, Marketa Bloomfield
J Clin Immunol. 2023; 43(7): 1640–1659. Published online 2023 Jun 26. doi: 10.1007/s10875-023-01528-1
PMCID:
PMC10499747
AbstractArticlePDF–4.6M
15.
CYLD stimulates macrophage phagocytosis of leukemic cells through STAT1 signalling in acute myeloid leukemia
Nguyen Thanh Huyen, Nguyen Thy Ngoc, Nguyen Hoang Giang, Do Thi Trang, Ha Hong Hanh, Vu Duc Binh, Nguyen Van Giang, Nguyen Xuan Canh, Nguyen Thi Xuan
PLoS One. 2023; 18(8): e0283586. Published online 2023 Aug 7. doi: 10.1371/journal.pone.0283586
PMCID:
PMC10406188
AbstractArticlePDF–1.8M
16.
A rare mutation causing autosomal dominant STAT1 deficiency in a South African multiplex kindred with disseminated BCG infection
Leonore Greybe, Daniel Leung, Nicole Wieselthaler, David M le Roux, Koon Wing Chan, Yu Lung Lau, Brian Eley
BMC Pediatr. 2023; 23: 378. Published online 2023 Jul 29. doi: 10.1186/s12887-023-04206-8
PMCID:
PMC10386767
AbstractArticlePDF–2.0M
17.
Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity
Xiuting Liu, Graham D. Hogg, Chong Zuo, Nicholas C. Borcherding, John M. Baer, Varintra E. Lander, Liang-I Kang, Brett L. Knolhoff, Faiz Ahmad, Robin E. Osterhout, Anna V. Galkin, Jean-Marie Bruey, Laura L. Carter, Cedric Mpoy, Kiran R Vij, Ryan C. Fields, Julie K. Schwarz, Haeseong Park, Vineet Gupta, David G. DeNardo
Cancer Cell. Author manuscript; available in PMC 2024 Jun 12.
Published in final edited form as: Cancer Cell. 2023 Jun 12; 41(6): 1073–1090.e12. Published online 2023 May 25. doi: 10.1016/j.ccell.2023.04.018
PMCID:
PMC10281762
AbstractArticlePDF–4.3M
18.
Ablation of endothelial Atg7 inhibits ischemia-induced angiogenesis by upregulating Stat1 that suppresses Hif1a expression
Hongmin Yao, Jian Li, Zhixue Liu, Changhan Ouyang, Yu Qiu, Xiaoxu Zheng, Jing Mu, Zhonglin Xie
Autophagy. 2023; 19(5): 1491–1511. Published online 2022 Nov 21. doi: 10.1080/15548627.2022.2139920
PMCID:
PMC10240988
AbstractArticlePDF–3.6M
19.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
20.
Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction
Amy E Spens, Nicholas A Sutliff, Sean R Bennett, Amy E Campbell, Stephen J Tapscott
eLife. 2023; 12: e82057. Published online 2023 Apr 24. doi: 10.7554/eLife.82057
PMCID:
PMC10195082
AbstractArticlePDF–3.6M

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