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Select item 106382391.

Activation-induced cytidine deaminase an antibody diversification enzyme interacts with chromatin modifier UBN1 in B-cells

Ankit Jaiswal, Rajarshi Roy, Anubhav Tamrakar, Amit Kumar Singh, Parimal Kar, Prashant Kodgire

Sci Rep. 2023; 13: 19615. Published online 2023 Nov 10. doi: 10.1038/s41598-023-46448-7

PMCID:: PMC10638239

Abstract Article PDF–2.9M

Select item 104362232.

The off-target effects of AID in carcinogenesis

Junna Jiao, Zhuangwei Lv, Yurong Wang, Liye Fan, Angang Yang

Front Immunol. 2023; 14: 1221528. Published online 2023 Aug 4. doi: 10.3389/fimmu.2023.1221528

PMCID:: PMC10436223

Abstract Article PDF–1.1M

Select item 93062953.

Frequent expression of activation induced cytidine deaminase in diffuse large B-cell lymphoma tissues from persons living with HIV

Volodymyr SHPONKA, Candace Y. REVELES, Sinthia ALAM, Melba JARAMILLO, Alanna MAGUIRE, Lisa M. RIMSZA, Samantha KENDRICK

AIDS. Author manuscript; available in PMC 2022 Jul 22.

Published in final edited form as: AIDS. 2020 Nov 15; 34(14): 2025–2035. doi: 10.1097/QAD.0000000000002653

PMCID:: PMC9306295

Abstract Article PDF–1.5M

Select item 91226044.

Human activation-induced deaminase lacks strong replicative strand bias or preference for cytosines in hairpin loops

Ramin Sakhtemani, Madusha L W Perera, Daniel Hübschmann, Reiner Siebert, Michael S Lawrence, Ashok S Bhagwat

Nucleic Acids Res. 2022 May 20; 50(9): 5145–5157. Published online 2022 May 7. doi: 10.1093/nar/gkac296

PMCID:: PMC9122604

Abstract Article PDF–2.4M

Select item 89231565.

Activation-induced deaminase and its splice variants associate with trisomy 12 in chronic lymphocytic leukemia

Kristina Zaprazna, Kamila Reblova, Veronika Svobodova, Lenka Radova, Vojtech Bystry, Jiri Baloun, Kristina Durechova, Nikola Tom, Tomas Loja, Martina Buresova, Kamila Stranska, Alexandra Oltova, Michael Doubek, Michael L. Atchison, Martin Trbusek, Jitka Malcikova, Sarka Pospisilova

Ann Hematol. Author manuscript; available in PMC 2022 Mar 15.

Published in final edited form as: Ann Hematol. 2019 Feb; 98(2): 423–435. Published online 2018 Oct 27. doi: 10.1007/s00277-018-3520-5

PMCID:: PMC8923156

Abstract Article PDF–1.1M

Select item 87247566.

USP10 regulates B cell response to SARS-CoV-2 or HIV-1 nanoparticle vaccines through deubiquitinating AID

Yuewen Luo, Xiantao Zhang, Ran Chen, Rong Li, Yang Liu, Junsong Zhang, Qin liu, Meijun Si, Jun Liu, Bolin Wu, Xuemei Wang, Shijian Wu, Yiwen Zhang, Xu Zhang, Deyin Guo, Xin He, Ting Pan, Hui Zhang

Signal Transduct Target Ther. 2022; 7: 7. Published online 2022 Jan 4. doi: 10.1038/s41392-021-00858-z

PMCID:: PMC8724756

Abstract Article PDF–5.0M

Select item 82898087.

Support of BCP-ALL-cells by autologous bone marrow Th-cells involves induction of AID expression but not widespread AID off-target mutagenesis

Sabrina Traxel, Julia Lehmann, Stefanie Richard, Semjon Sidorov, Felix Niggli, Christoph Berger, David Nadal, Simone Bürgler

Cancer Immunol Immunother. 2021 Aug; 70(8): 2275–2289. Published online 2021 Jan 28. doi: 10.1007/s00262-020-02835-x

PMCID:: PMC8289808

Abstract Article PDF–3.7M

Select item 81367778.

Activation-induced deaminase is critical for the establishment of DNA methylation patterns prior to the germinal center reaction

Francesc Català-Moll, Anna G Ferreté-Bonastre, Tianlu Li, Dieter Weichenhan, Pavlo Lutsik, Laura Ciudad, Ángel F Álvarez-Prado, Javier Rodríguez-Ubreva, Christian Klemann, Carsten Speckmann, Amaya Vilas-Zornoza, Hassan Abolhassani, Mónica Martínez-Gallo, Romina Dieli-Crimi, Jacques G Rivière, Andrea Martín-Nalda, Roger Colobran, Pere Soler-Palacín, Sven Kracker, Lennart Hammarström, Felipe Prosper, Anne Durandy, Bodo Grimbacher, Christoph Plass, Esteban Ballestar

Nucleic Acids Res. 2021 May 21; 49(9): 5057–5073. Published online 2021 May 5. doi: 10.1093/nar/gkab322

PMCID:: PMC8136777

Abstract Article PDF–2.5M

Select item 80712269.

Upregulated Expression of Activation-Induced Cytidine Deaminase in Ocular Adnexal Marginal Zone Lymphoma with IgG4-Positive Cells

Asami Nishikori, Yoshito Nishimura, Rei Shibata, Koh-ichi Ohshima, Yuka Gion, Tomoka Ikeda, Midori Filiz Nishimura, Tadashi Yoshino, Yasuharu Sato

Int J Mol Sci. 2021 Apr; 22(8): 4083. Published online 2021 Apr 15. doi: 10.3390/ijms22084083

PMCID:: PMC8071226

Abstract Article PDF–3.0M

Select item 797970510.

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1

Xiahui Li, Shujing Li, Bowen Li, Yanan Li, Sattout Aman, Kangkai Xia, Yuxi Yang, Bashir Ahmad, Huijian Wu

NPJ Precis Oncol. 2021; 5: 20. Published online 2021 Mar 19. doi: 10.1038/s41698-021-00158-3

PMCID:: PMC7979705

Abstract Article PDF–6.8M

Select item 771361611.

Role of activation‐induced cytidine deaminase in the progression of follicular lymphoma

Hisaharu Shikata, Yoshihiro Yakushijin, Natsuki Matsushita, Akira Sakai, Atsuro Sugita, Naoya Nakamura, Jun Yamanouchi, Taichi Azuma, Takaaki Hato, Masaki Yasukawa

Cancer Sci. 2012 Mar; 103(3): 415–421. Published online 2012 Jan 17. doi: 10.1111/j.1349-7006.2011.02186.x

PMCID:: PMC7713616

Abstract Article PDF–572K

Select item 765929212.

Inflammation‐mediated genomic instability: roles of activation‐induced cytidine deaminase in carcinogenesis

Takahiro Shimizu, Hiroyuki Marusawa, Yoko Endo, Tsutomu Chiba

Cancer Sci. 2012 Jul; 103(7): 1201–1206. Published online 2012 May 11. doi: 10.1111/j.1349-7006.2012.02293.x

PMCID:: PMC7659292

Abstract Article PDF–376K

Select item 761344513.

Epstein–Barr virus and malaria upregulate AID and APOBEC3 enzymes, but only AID seems to play a major mutagenic role in Burkitt lymphoma

Andrea M. Summerauer, Vera Jäggi, Rodney Ogwang, Sabrina Traxel, Lorenzo Colombo, Eivind Amundsen, Tatjana Eyer, Bibin Subramanian, Jan Fehr, Pierre‐Yves Mantel, Richard Idro, Simone Bürgler

Eur J Immunol. 2022 Aug; 52(8): 1273–1284. Published online 2022 May 12. doi: 10.1002/eji.202249820

PMCID:: PMC7613445

Abstract Article PDF–1.5M

Select item 745939914.

Optimized high‐fidelity 3DPCR to assess potential mitochondrial targeting by activation‐induced cytidine deaminase

Haiyan Wu, Kaili Zhang, Yue Chen, Jinfeng Li, Matthew P. Strout, Xiwen Gu

FEBS Open Bio. 2020 Sep; 10(9): 1782–1792. Published online 2020 Aug 13. doi: 10.1002/2211-5463.12927

PMCID:: PMC7459399

Abstract Article PDF–1.1M

Select item 744763915.

Activation-induced cytidine deaminase overexpression in double-hit lymphoma: potential target for novel anticancer therapy

Jingcheng Zhang, Yifen Shi, Mingzhe Zhao, Huixian Hu, He Huang

Sci Rep. 2020; 10: 14164. Published online 2020 Aug 25. doi: 10.1038/s41598-020-71058-y

PMCID:: PMC7447639

Abstract Article PDF–7.0M

Select item 726113316.

RNA-binding motifs of hnRNP K are critical for induction of antibody diversification by activation-induced cytidine deaminase

Ziwei Yin, Maki Kobayashi, Wenjun Hu, Koichi Higashi, Nasim A. Begum, Ken Kurokawa, Tasuku Honjo

Proc Natl Acad Sci U S A. 2020 May 26; 117(21): 11624–11635. Published online 2020 May 8. doi: 10.1073/pnas.1921115117

PMCID:: PMC7261133

Abstract Article PDF–2.9M

Select item 720454517.

AID Overlapping and Polη Hotspots Are Key Features of Evolutionary Variation Within the Human Antibody Heavy Chain (IGHV) Genes

Catherine Tang, Davide Bagnara, Nicholas Chiorazzi, Matthew D. Scharff, Thomas MacCarthy

Front Immunol. 2020; 11: 788. Published online 2020 Apr 30. doi: 10.3389/fimmu.2020.00788

PMCID:: PMC7204545

Abstract Article PDF–1.0M

Select item 684665618.

AID–RNA polymerase II transcription-dependent deamination of IgV DNA

Phuong Pham, Sohail Malik, Chiho Mak, Peter C Calabrese, Robert G Roeder, Myron F Goodman

Nucleic Acids Res. 2019 Nov 18; 47(20): 10815–10829. Published online 2019 Sep 30. doi: 10.1093/nar/gkz821

PMCID:: PMC6846656

Abstract Article PDF–3.9M

Select item 669866519.

Restriction of AID activity and somatic hypermutation by PARP-1

Sandra Tepper, Oliver Mortusewicz, Ewelina Członka, Amanda Bello, Angelika Schmidt, Julia Jeschke, Arthur Fischbach, Ines Pfeil, Svend K Petersen-Mahrt, Aswin Mangerich, Thomas Helleday, Heinrich Leonhardt, Berit Jungnickel

Nucleic Acids Res. 2019 Aug 22; 47(14): 7418–7429. Published online 2019 May 25. doi: 10.1093/nar/gkz466

PMCID:: PMC6698665

Abstract Article PDF–4.2M

Select item 642050320.

AID modulates carcinogenesis network via DNA demethylation in bladder urothelial cell carcinoma

Haoyong Li, Qi Li, Zhe Ma, Zhiyan Zhou, Jinfeng Fan, Yingxia Jin, Yaoxi Wu, Fan Cheng, Peiyu Liang

Cell Death Dis. 2019 Apr; 10(4): 251. Published online 2019 Mar 15. doi: 10.1038/s41419-019-1472-x

PMCID:: PMC6420503

Abstract Article PDF–4.6M

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