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Select item 114575051.

Gene correction and overexpression of TNNI3 improve impaired relaxation in engineered heart tissue model of pediatric restrictive cardiomyopathy

Moyu Hasegawa, Kenji Miki, Takuji Kawamura, Ikue Takei Sasozaki, Yuki Higashiyama, Masaru Tsuchida, Kunio Kashino, Masaki Taira, Emiko Ito, Maki Takeda, Hidekazu Ishida, Shuichiro Higo, Yasushi Sakata, Shigeru Miyagawa

Dev Growth Differ. 2024 Feb; 66(2): 119–132. Published online 2024 Jan 9. doi: 10.1111/dgd.12909

PMCID:: PMC11457505

Abstract Article PDF–2.6M

Select item 114271302.

Galectin-3, Acute Kidney Injury and Myocardial Damage in Patients With Acute Heart Failure

YU HORIUCHI, NICHOLAS WETTERSTEN, DIRK J. VAN VELDHUISEN, CHRISTIAN MUELLER, GERASIMOS FILIPPATOS, RICHARD NOWAK, CHRISTOPHER HOGAN, MICHAEL C. KONTOS, CHAD M. CANNON, GERHARD A. MÜELLER, ROBERT BIRKHAHN, PAM TAUB, GARY M. VILKE, KENNETH MCDONALD, NIALL MAHON, JULIO NUÑEZ, CARLO BRIGUORI, CLAUDIO PASSINO, STEPHEN DUFF, ALAN MAISEL, PATRICK T. MURRAY

J Card Fail. Author manuscript; available in PMC 2024 Sep 27.

Published in final edited form as: J Card Fail. 2023 Mar; 29(3): 269–277. Published online 2022 Nov 1. doi: 10.1016/j.cardfail.2022.09.017

PMCID:: PMC11427130

Abstract Article PDF–792K

Select item 111969963.

Homozygous TNNI3 frameshift variant in a consanguineous family with lethal infantile dilated cardiomyopathy

Lilia Kraoua, Assaad Louati, Sarra Ben Ahmed, Nesrine Abida, Monia Khemiri, Khaled Menif, Ridha Mrad, Stéphane Zaffran, Hager Jaouadi

Mol Genet Genomic Med. 2024 Jun; 12(6): e2486. Published online 2024 Jun 25. doi: 10.1002/mgg3.2486

PMCID:: PMC11196996

Abstract Article PDF–2.3M

Select item 110574184.

Decreased intranuclear cardiac troponin I impairs cardiac autophagy through FOS/ATG5 in ageing hearts

Rui Min Liu, Shan Huang, Di Hu, Lingjuan Liu, Hui Chao Sun, Jie Tian, Bo Pan

J Cell Mol Med. 2024 May; 28(9): e18357. Published online 2024 Apr 29. doi: 10.1111/jcmm.18357

PMCID:: PMC11057418

Abstract Article PDF–6.8M

Select item 110100015.

Impaired Relaxation in Induced Pluripotent Stem Cell‐Derived Cardiomyocytes with Pathogenic TNNI3 Mutation of Pediatric Restrictive Cardiomyopathy

Renjie Wang, Moyu Hasegawa, Hidehiro Suginobe, Chika Yoshihara, Yoichiro Ishii, Atsuko Ueyama, Kazutoshi Ueda, Kazuhisa Hashimoto, Masaki Hirose, Ryo Ishii, Jun Narita, Takuji Watanabe, Takuji Kawamura, Masaki Taira, Takayoshi Ueno, Shigeru Miyagawa, Hidekazu Ishida

J Am Heart Assoc. 2024 Mar 19; 13(6): e032375. Published online 2024 Mar 16. doi: 10.1161/JAHA.123.032375

PMCID:: PMC11010001

Abstract Article PDF–5.6M

Select item 102799136.

AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity

Mario Ruiz, Ranjan Devkota, Delaney Kaper, Hanna Ruhanen, Kiran Busayavalasa, Uroš Radović, Marcus Henricsson, Reijo Käkelä, Jan Borén, Marc Pilon

J Biol Chem. 2023 Jun; 299(6): 104799. Published online 2023 May 8. doi: 10.1016/j.jbc.2023.104799

PMCID:: PMC10279913

Abstract Article PDF–4.1M

Select item 97157917.

Prognostic value of high‐sensitivity cardiac troponin I in patients with non‐ischaemic heart failure: insights from China

Pengchao Tian, Xuemei Zhao, Liyan Huang, Jiayu Feng, Lang Zhao, Lin Liang, Boping Huang, Yuhui Zhang, Jian Zhang

ESC Heart Fail. 2022 Oct; 9(5): 3345–3357. Published online 2022 Jul 13. doi: 10.1002/ehf2.14065

PMCID:: PMC9715791

Abstract Article PDF–3.2M

Select item 96281668.

Prognostic value of high-sensitivity cardiac troponin I early after coronary artery bypass graft surgery

Samuele Nanni, Mattia Garofalo, Matteo Schinzari, Elena Nardi, Franco Semprini, Paola Battistini, Francesco Barberini, Alberto Foà, Massimo Baiocchi, Andrea Castelli, Gianluca Folesani, Davide Pacini, Nazzareno Galiè, Anna Corsini

J Cardiothorac Surg. 2022; 17: 280. Published online 2022 Nov 1. doi: 10.1186/s13019-022-02027-x

PMCID:: PMC9628166

Abstract Article PDF–887K

Select item 96244279.

Diagnostic and prognostic performance of the ratio between high-sensitivity cardiac troponin I and troponin T in patients with chest pain

Kai M. Eggers, Ola Hammarsten, Sally J. Aldous, Louise Cullen, Jaimi H. Greenslade, Bertil Lindahl, William A. Parsonage, Christopher J. Pemberton, John W. Pickering, A. Mark Richards, Richard W. Troughton, Martin P. Than

PLoS One. 2022; 17(11): e0276645. Published online 2022 Nov 1. doi: 10.1371/journal.pone.0276645

PMCID:: PMC9624427

Abstract Article PDF–826K

Select item 958861210.

SUMOylation does not affect cardiac troponin I stability but alters indirectly the development of force in response to Ca²⁺

Bracy Fertig, Jiayue Ling, Edgar E. Nollet, Sara Dobi, Tara Busiau, Kiyotake Ishikawa, Kelly Yamada, Ahyoung Lee, Changwon Kho, Lauren Wills, Amy J. Tibbo, Mark Scott, Kirsten Grant, Kenneth S. Campbell, Emma J. Birks, Niall MacQuaide, Roger Hajjar, Godfrey L. Smith, Jolanda van der Velden, George S. Baillie

FEBS J. 2022 Oct; 289(20): 6267–6285. Published online 2022 Jun 8. doi: 10.1111/febs.16537

PMCID:: PMC9588612

Abstract Article PDF–2.5M

Select item 896111011.

Association of serum cardiac troponin I and severity of coronary stenosis in patients with varied renal functions: a retrospective cohort study

Qian Zhang, Yong-Fei Wang, Xiao Hu, Ya-Jun Tan, Cui Gao, Jianxiao Chen, Fei Han, Jianghua Chen, Yi Yang

BMJ Open. 2022; 12(3): e054722. Published online 2022 Mar 28. doi: 10.1136/bmjopen-2021-054722

PMCID:: PMC8961110

Abstract Article PDF–645K

Select item 895155612.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Abstract Article PDF–4.4M

Select item 883766513.

Role of a lower cutoff of high sensitivity troponin I in identification of early cardiac damage in non-severe patients with COVID-19

Yiting Lin, Kun Yan, Lingling Chen, Yiqun Wu, Jielan Liu, Yingying Chen, Bingbo Hou, Ping Zhong

Sci Rep. 2022; 12: 2389. Published online 2022 Feb 11. doi: 10.1038/s41598-022-06378-2

PMCID:: PMC8837665

Abstract Article PDF–1.3M

Select item 882082414.

Clinical implications of cardiac troponin-I in patients with hypertensive crisis visiting the emergency department

Woohyeun Kim, Byung Sik Kim, Hyun-Jin Kim, Jun Hyeok Lee, Jinho Shin, Jeong-Hun Shin

Ann Med. 2022; 54(1): 507–515. Published online 2022 Feb 3. doi: 10.1080/07853890.2022.2034934

PMCID:: PMC8820824

Abstract Article PDF–1.3M

Select item 874439015.

The ratio of cardiac troponin T to troponin I may indicate non-necrotic troponin release among COVID-19 patients

Ola Hammarsten, Pontus Ljungqvist, Björn Redfors, Mathias Wernbom, Hannes Widing, Bertil Lindahl, Sabin Salahuddin, Ruwayda Sammantar, Sandeep Jha, Annica Ravn-Fischer, Magnus Brink, Magnus Gisslen

Clin Chim Acta. 2022 Feb 15; 527: 33–37. Published online 2022 Jan 5. doi: 10.1016/j.cca.2021.12.030

PMCID:: PMC8744390

Abstract Article PDF–587K

Select item 848279316.

Troponin-Guided Coronary Computed Tomographic Angiography After Exclusion of Myocardial Infarction

Kuan Ken Lee, Anda Bularga, Rachel O’Brien, Amy V. Ferry, Dimitrios Doudesis, Takeshi Fujisawa, Shauna Kelly, Stacey Stewart, Ryan Wereski, Denise Cranley, Edwin J.R. van Beek, David J. Lowe, David E. Newby, Michelle C. Williams, Alasdair J. Gray, Nicholas L. Mills

J Am Coll Cardiol. 2021 Oct 5; 78(14): 1407–1417. doi: 10.1016/j.jacc.2021.07.055

PMCID:: PMC8482793

Abstract Article PDF–965K

Select item 843179817.

De Novo Missense Mutations in TNNC1 and TNNI3 Causing Severe Infantile Cardiomyopathy Affect Myofilament Structure and Function and Are Modulated by Troponin Targeting Agents

Roua Hassoun, Heidi Budde, Hans Georg Mannherz, Mária Lódi, Setsuko Fujita-Becker, Kai Thorsten Laser, Anna Gärtner, Karin Klingel, Desirée Möhner, Robert Stehle, Innas Sultana, Thomas Schaaf, Mario Majchrzak, Verena Krause, Christian Herrmann, Marc M. Nowaczyk, Andreas Mügge, Gabriele Pfitzer, Rasmus R. Schröder, Nazha Hamdani, Hendrik Milting, Kornelia Jaquet, Diana Cimiotti

Int J Mol Sci. 2021 Sep; 22(17): 9625. Published online 2021 Sep 6. doi: 10.3390/ijms22179625

PMCID:: PMC8431798

Abstract Article PDF–7.1M

Select item 841243418.

The role of antibody-based troponin detection in cardiovascular disease: A critical assessment

Hui Ma, Arabelle Cassedy, Richard O'Kennedy

J Immunol Methods. 2021 Oct; 497: 113108. Published online 2021 Jul 28. doi: 10.1016/j.jim.2021.113108

PMCID:: PMC8412434

Abstract Article PDF–1.8M

Select item 839501419.

A Novel Missense Mutation in TNNI3K Causes Recessively Inherited Cardiac Conduction Disease in a Consanguineous Pakistani Family

Shafaq Ramzan, Stephanie Tennstedt, Muhammad Tariq, Sheraz Khan, Hafiza Noor Ul Ayan, Aamir Ali, Matthias Munz, Holger Thiele, Asad Aslam Korejo, Abdul Razzaq Mughal, Syed Zahid Jamal, Peter Nürnberg, Shahid Mahmood Baig, Jeanette Erdmann, Ilyas Ahmad

Genes (Basel) 2021 Aug; 12(8): 1282. Published online 2021 Aug 21. doi: 10.3390/genes12081282

PMCID:: PMC8395014

Abstract Article PDF–1.6M

Select item 816503020.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

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