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Select item 112157881.

Epigenetic and sex differences in opioid use disorder in chronic pain: A real‐world study linked with OPRM1 DNA methylation

Laura Agulló, Mónica Escorial, Samantha Orutño, Javier Muriel, Juan Sandoval, César Margarit, Ana M. Peiró

Addict Biol. 2024 Jul; 29(7): e13422. Published online 2024 Jul 1. doi: 10.1111/adb.13422

PMCID:: PMC11215788

Abstract Article PDF–1.1M

Select item 111155512.

Differential use of an in-frame translation initiation codon regulates human mu opioid receptor (OPRM1)

Kyu Young Song, Hack Sun Choi, Cheol Kyu Hwang, Chun Sung Kim, Ping-Yee Law, Li-Na Wei, Horace H. Loh

Cell Mol Life Sci. 2009 Sep; 66(17): 2933–2942. Published online 2009 Jul 16. doi: 10.1007/s00018-009-0082-7

PMCID:: PMC11115551

Abstract Article PDF–434K

Select item 109977753.

Variation in the mu-opioid receptor gene (OPRM1) moderates the influence of maternal sensitivity on child attachment

K. Tchalova, J. E. Lydon, L. Atkinson, A. S. Fleming, J. Kennedy, V. Lecompte, M. J. Meaney, E. Moss, K. A. O’Donnell, K. J. O’Donnell, P. P. Silveira, M. B. Sokolowski, M. Steiner, J. A. Bartz

Transl Psychiatry. 2024; 14: 181. Published online 2024 Apr 5. doi: 10.1038/s41398-024-02888-x

PMCID:: PMC10997775

Abstract Article PDF–639K

Select item 109317194.

OPRM1 Gene Polymorphism in Women with Alcohol Use Disorder

Agnieszka Boroń, Aleksandra Suchanecka, Krzysztof Chmielowiec, Małgorzata Śmiarowska, Jolanta Chmielowiec, Aleksandra Strońska-Pluta, Remigiusz Recław, Anna Grzywacz

Int J Mol Sci. 2024 Mar; 25(5): 3067. Published online 2024 Mar 6. doi: 10.3390/ijms25053067

PMCID:: PMC10931719

Abstract Article PDF–435K

Select item 108987935.

Polymorphisms in the A118G SNP of the OPRM1 gene produce different experiences of opioids: A human laboratory phenotype–genotype assessment

Kelly E. Dunn, Andrew S. Huhn, Patrick H. Finan, Ami Mange, Cecilia L. Bergeria, Brion S. Maher, Jill A. Rabinowitz, Eric C. Strain, Denis Antoine

Addict Biol. 2024 Jan; 29(1): e13355. Published online 2023 Dec 19. doi: 10.1111/adb.13355

PMCID:: PMC10898793

Abstract Article PDF–1.2M

Select item 106487026.

A novel tetra-primer ARMS-PCR for genotyping of the OPRM1 gene rs1799971 variant associated with opioid use disorders

P. J. Wijekumar, N. D.K. Ranadeva, A. R. Jayamaha, H. M.N.D.M. Herath, N. Noorden, S. S.N. Fernando

BMC Res Notes. 2023; 16: 333. Published online 2023 Nov 14. doi: 10.1186/s13104-023-06578-7

PMCID:: PMC10648702

Abstract Article PDF–1.2M

Select item 104998917.

Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to μ-opioidergic cell types

Gregory J. Salimando, Sébastien Tremblay, Blake A. Kimmey, Jia Li, Sophie A. Rogers, Jessica A. Wojick, Nora M. McCall, Lisa M. Wooldridge, Amrith Rodrigues, Tito Borner, Kristin L. Gardiner, Selwyn S. Jayakar, Ilyas Singeç, Clifford J. Woolf, Matthew R. Hayes, Bart C. De Jonghe, F. Christian Bennett, Mariko L. Bennett, Julie A. Blendy, Michael L. Platt, Kate Townsend Creasy, William R. Renthal, Charu Ramakrishnan, Karl Deisseroth, Gregory Corder

Nat Commun. 2023; 14: 5632. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41407-2

PMCID:: PMC10499891

Abstract Article PDF–16M

Select item 102017268.

Is OPRM1 genotype a valuable predictor of VAS in patients undergoing laparoscopic radical resection of colorectal cancer with fentanyl?

Yan Zhou, Lei Cao, Yihui Yang, Yaoyi Gao, Yihao Li, Beili Wang, Baishen Pan, Jian Huang, Wei Guo

BMC Anesthesiol. 2023; 23: 173. Published online 2023 May 22. doi: 10.1186/s12871-023-02120-1

PMCID:: PMC10201726

Abstract Article PDF–1.0M

Select item 101575249.

MOR promotes epithelial-mesenchymal transition and proliferation via PI3K/AKT signaling pathway in human colorectal cancer: MOR promotes EMT and proliferation

Lingling Gao, Li Yang, Yiping He, Yi Liu, Pinbo Xu, Jun Zhang, Sailin Dai, Xing Luo, Zhirong Sun

Acta Biochim Biophys Sin (Shanghai) 2023 Jan; 55(1): 72–80. Published online 2022 Aug 18. doi: 10.3724/abbs.2022114

PMCID:: PMC10157524

Abstract Article PDF–8.9M

Select item 1003947810.

Association of OPRM1, MIR23B, and MIR107 Genetic Variability with Acute Pain, Chronic Pain and Adverse Effects after Postoperative Tramadol and Paracetamol Treatment in Breast Cancer

Zala Vidic, Katja Goricar, Branka Strazisar, Nikola Besic, Prof. Vita Dolzan

Radiol Oncol. 2023 Mar; 57(1): 111–120. Published online 2023 Mar 22. doi: 10.2478/raon-2023-0003

PMCID:: PMC10039478

Abstract Article PDF–376K

Select item 985858411.

Polymorphisms in COMT and OPRM1 Collectively Contribute to Chronic Shoulder Pain and Disability in South African Breast Cancer Survivors’

Firzana Firfirey, Delva Shamley, Alison V. September

Genes (Basel) 2023 Jan; 14(1): 9. Published online 2022 Dec 21. doi: 10.3390/genes14010009

PMCID:: PMC9858584

Abstract Article PDF–1.2M

Select item 970188512.

Association between rs1799971 in the mu opioid receptor gene and methadone maintenance treatment response

Xiaohu Xie, Jun Gu, Dingding Zhuang, Yun Zhou, Xiaoyu Chen, Wenwen Shen, Longhui Li, Yue Liu, Wenjin Xu, Qingxiao Hong, Zemin Xu, Weisheng Chen, Wenhua Zhou, Huifen Liu

J Clin Lab Anal. 2022 Nov; 36(11): e24750. Published online 2022 Oct 28. doi: 10.1002/jcla.24750

PMCID:: PMC9701885

Abstract Article PDF–312K

Select item 963984113.

The OPRM1 gene and interactions with the 5-HT1a gene regulate conditioned pain modulation in fibromyalgia patients and healthy controls

Jeanette Tour, Angelica Sandström, Diana Kadetoff, Martin Schalling, Eva Kosek

PLoS One. 2022; 17(11): e0277427. Published online 2022 Nov 7. doi: 10.1371/journal.pone.0277427

PMCID:: PMC9639841

Abstract Article PDF–1.0M

Select item 960243114.

No Association between Genetic Variants of the COMT and OPRM1 Genes and Pain Perception among Patients Undergoing Total Hip or Knee Arthroplasty for Primary Osteoarthritis

Alina Jurewicz, Andrzej Bohatyrewicz, Maciej Pawlak, Maciej Tarnowski, Mateusz Kurzawski, Anna Machoy-Mokrzyńska, Mariusz Kaczmarczyk, Anna Lubkowska, Monika Chudecka, Agnieszka Maciejewska-Skrendo, Katarzyna Leźnicka

Genes (Basel) 2022 Oct; 13(10): 1775. Published online 2022 Oct 1. doi: 10.3390/genes13101775

PMCID:: PMC9602431

Abstract Article PDF–274K

Select item 930485315.

Associations of the A118G OPRM1 polymorphism with sociotropy and interpersonal sensitivity

Akihito Suzuki, Toshinori Shirata, Keisuke Noto, Yoshihiko Matsumoto, Haruka Muraosa, Mio Abe, Kaoru Goto, Koichi Otani

Brain Behav. 2022 Jul; 12(7): e2674. Published online 2022 Jun 27. doi: 10.1002/brb3.2674

PMCID:: PMC9304853

Abstract Article PDF–328K

Select item 910767216.

Beta 2 adrenergic receptor and mu opioid receptor interact to potentiate the aggressiveness of human breast cancer cell by activating the glycogen synthase kinase 3 signaling

Bénédicte Rousseau, Sengottuvelan Murugan, Ajay Palagani, Dipak K. Sarkar

Breast Cancer Res. 2022; 24: 33. Published online 2022 May 14. doi: 10.1186/s13058-022-01526-y

PMCID:: PMC9107672

Abstract Article PDF–7.6M

Select item 885900817.

Modulation of OPRM1 alternative splicing by morphine and HIV-1 Nef

Martina Donadoni, Wenfei Huang, Shadan S. Yarandi, Tricia H. Burdo, Sulie L. Chang, Ilker K. Sariyer

J Neuroimmune Pharmacol. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: J Neuroimmune Pharmacol. 2022 Jun; 17(1-2): 277–288. Published online 2021 Aug 21. doi: 10.1007/s11481-021-10009-4

PMCID:: PMC8859008

Abstract Article PDF–1.7M

Select item 867361618.

Implications of OPRM1 and CYP2B6 variants on treatment outcomes in methadone-maintained patients in Ontario: Exploring sex differences

Caroul Chawar, Alannah Hillmer, Amel Lamri, Flavio Kapczinski, Lehana Thabane, Guillaume Pare, Zainab Samaan

PLoS One. 2021; 16(12): e0261201. Published online 2021 Dec 15. doi: 10.1371/journal.pone.0261201

PMCID:: PMC8673616

Abstract Article PDF–511K

Select item 856842019.

Influence of genetic variants of opioid-related genes on opioid-induced adverse effects in patients with lung cancer: A STROBE-compliant observational study

Rei Tanaka, Junya Sato, Hiroshi Ishikawa, Tetsu Sato, Michihiro Shino, Yasuhisa Ohde, Tetsumi Sato, Keita Mori, Akifumi Notsu, Sumiko Ohnami, Maki Mizuguchi, Takeshi Nagashima, Ken Yamaguchi

Medicine (Baltimore) 2021 Nov 5; 100(44): e27565. Published online 2021 Nov 5. doi: 10.1097/MD.0000000000027565

Correction in:: Medicine (Baltimore). 2021 Dec 23; 100(51): e28405.

PMCID:: PMC8568420

Abstract Article PDF–444K

Select item 853403120.

Alternative Pre-mRNA Splicing of the Mu Opioid Receptor Gene, OPRM1: Insight into Complex Mu Opioid Actions

Shan Liu, Wen-Jia Kang, Anna Abrimian, Jin Xu, Luca Cartegni, Susruta Majumdar, Patrick Hesketh, Alex Bekker, Ying-Xian Pan

Biomolecules. 2021 Oct; 11(10): 1525. Published online 2021 Oct 15. doi: 10.3390/biom11101525

PMCID:: PMC8534031

Abstract Article PDF–2.6M

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