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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 106798402.

Active maintenance of CD8⁺ T cell naivety through regulation of global genome architecture

Brendan E. Russ, Adele Barugahare, Pushkar Dakle, Kirril Tsyganov, Sara Quon, Bingfei Yu, Jasmine Li, Jason K.C. Lee, Moshe Olshansky, Zhaohren He, Paul F. Harrison, Michael See, Simone Nussing, Alison E. Morey, Vibha A. Udupa, Taylah J. Bennett, Axel Kallies, Cornelis Murre, Phillipe Collas, David Powell, Ananda W. Goldrath, Stephen J. Turner

Cell Rep. Author manuscript; available in PMC 2023 Nov 27.

Published in final edited form as: Cell Rep. 2023 Oct 31; 42(10): 113301. Published online 2023 Oct 19. doi: 10.1016/j.celrep.2023.113301

PMCID:: PMC10679840

Abstract Article PDF–2.7M

Select item 98286763.

Super‐killer CTLs are generated by single gene deletion of Bach2

Philippa R. Barton, Alexander J. Davenport, Jens Hukelmann, Doreen A. Cantrell, Jane C. Stinchcombe, Arianne C. Richard, Gillian M Griffiths

Eur J Immunol. 2022 Nov; 52(11): 1776–1788. Published online 2022 Sep 26. doi: 10.1002/eji.202249797

PMCID:: PMC9828676

Abstract Article PDF–4.4M

Select item 97937784.

Prioritization of autoimmune disease-associated genetic variants that perturb regulatory element activity in T cells

Kousuke Mouri, Michael H. Guo, Carl G. de Boer, Michelle M. Lissner, Ingrid A. Harten, Gregory A. Newby, Hannah A. DeBerg, Winona F. Platt, Matteo Gentili, David R. Liu, Daniel J. Campbell, Nir Hacohen, Ryan Tewhey, John P. Ray

Nat Genet. Author manuscript; available in PMC 2022 Dec 27.

Published in final edited form as: Nat Genet. 2022 May; 54(5): 603–612. Published online 2022 May 5. doi: 10.1038/s41588-022-01056-5

PMCID:: PMC9793778

Abstract Article PDF–5.5M

Select item 97713655.

TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development

Jifan Feng, Xia Han, Yuan Yuan, Courtney Kyeong Cho, Eva Janečková, Tingwei Guo, Siddhika Pareek, Md Shaifur Rahman, Banghong Zheng, Jing Bi, Junjun Jing, Mingyi Zhang, Jian Xu, Thach-Vu Ho, Yang Chai

eLife. 2022; 11: e80405. Published online 2022 Dec 21. doi: 10.7554/eLife.80405

PMCID:: PMC9771365

Abstract Article PDF–17M

Select item 95601526.

The transcription factor Bach2 negatively regulates murine natural killer cell maturation and function

Shasha Li, Michael D Bern, Benpeng Miao, Changxu Fan, Xiaoyun Xing, Takeshi Inoue, Sytse J Piersma, Ting Wang, Marco Colonna, Tomohiro Kurosaki, Wayne M Yokoyama

eLife. 2022; 11: e77294. Published online 2022 Oct 3. doi: 10.7554/eLife.77294

PMCID:: PMC9560152

Abstract Article PDF–5.3M

Select item 95501887.

Diverging regulation of Bach2 protein and RNA expression determine cell fate in early B-cell response

Qianwen Hu, Tingting Xu, Min Zhang, Heng Zhang, Yongbo Liu, Hua-bing Li, Chiqi Chen, Junke Zheng, Zhen Zhang, Fubin Li, Nan Shen, Wenqian Zhang, Ari Melnick, Chuanxin Huang

Cell Rep. Author manuscript; available in PMC 2022 Oct 10.

Published in final edited form as: Cell Rep. 2022 Jul 5; 40(1): 111035. doi: 10.1016/j.celrep.2022.111035

PMCID:: PMC9550188

Abstract Article PDF–971K

Select item 95296148.

BACH2 restricts NK cell maturation and function, limiting immunity to cancer metastasis

Charlotte J. Imianowski, Sarah K. Whiteside, Teresa Lozano, Alexander C. Evans, Jayme D. Benson, Christina J.F. Courreges, Firas Sadiyah, Colleen M. Lau, Nordin D. Zandhuis, Francis M. Grant, Martijn J. Schuijs, Panagiota Vardaka, Paula Kuo, Elizabeth J. Soilleux, Jie Yang, Joseph C. Sun, Tomohiro Kurosaki, Klaus Okkenhaug, Timotheus Y.F. Halim, Rahul Roychoudhuri

J Exp Med. 2022 Dec 5; 219(12): e20211476. Published online 2022 Sep 30. doi: 10.1084/jem.20211476

PMCID:: PMC9529614

Abstract Article PDF–5.6M

Select item 94654869.

Protections of transcription factor BACH2 and natural product myricetin against pathological cardiac hypertrophy and dysfunction

Xueli Jiang, Mengying Cao, Jian Wu, Xiaolin Wang, Guoping Zhang, Chunjie Yang, Pan Gao, Yunzeng Zou

Front Physiol. 2022; 13: 971424. Published online 2022 Aug 29. doi: 10.3389/fphys.2022.971424

PMCID:: PMC9465486

Abstract Article PDF–3.5M

Select item 941086810.

BACH2 in TRegs Limits the Number of Adipose Tissue Regulatory T Cells and Restrains Type 2 Immunity to Fungal Allergens

Amanda Contreras, Darin L. Wiesner, Brock Kingstad-Bakke, Woojong Lee, John P. Svaren, Bruce S. Klein, M. Suresh

J Immunol Res. 2022; 2022: 6789055. Published online 2022 Aug 5. doi: 10.1155/2022/6789055

PMCID:: PMC9410868

Abstract Article PDF–1.2M

Select item 844633811.

ACAA2 is a Ligand-dependent Coactivator for Thyroid Hormone Receptor β1

Wesley Wang, Dolena Ledee

Biochem Biophys Res Commun. Author manuscript; available in PMC 2022 Oct 22.

Published in final edited form as: Biochem Biophys Res Commun. 2021 Oct 22; 576: 15–21. Published online 2021 Aug 28. doi: 10.1016/j.bbrc.2021.08.073

PMCID:: PMC8446338

Abstract Article PDF–830K

Select item 839558712.

Continuous culture of mouse primary B lymphocytes by forced expression of Bach2

Joel Finney, Garnett Kelsoe

J Immunol. Author manuscript; available in PMC 2022 Sep 1.

Published in final edited form as: J Immunol. 2021 Sep 1; 207(5): 1478–1492. Published online 2021 Aug 13. doi: 10.4049/jimmunol.2100172

PMCID:: PMC8395587

Abstract Article PDF–1.4M

Select item 831323913.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 793877014.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 790695615.

BACH2 Enforces the Transcriptional and Epigenetic Programs of Stem-Like CD8⁺ T cells

Chen Yao, Guohua Lou, Hong-Wei Sun, Ziang Zhu, Yi Sun, Zeyu Chen, Daniel Chauss, E. Ashley Moseman, Jun Cheng, Marc A. D’Antonio, Wangke Shi, Junwei Shi, Kohei Kometani, Tomohiro Kurosaki, E. John Wherry, Behdad Afzali, Luca Gattinoni, Yuwen Zhu, Dorian B. McGavern, John J. O’Shea, Pamela L. Schwartzberg, Tuoqi Wu

Nat Immunol. Author manuscript; available in PMC 2021 Aug 11.

Published in final edited form as: Nat Immunol. 2021 Mar; 22(3): 370–380. Published online 2021 Feb 11. doi: 10.1038/s41590-021-00868-7

PMCID:: PMC7906956

Abstract Article PDF–4.7M

Select item 789758116.

Bach2 Deficiency Promotes Intestinal Epithelial Regeneration by Accelerating DNA Repair in Intestinal Stem Cells

Yuanchuang Li, Xinxin Rao, Peiyuan Tang, Shengzhi Chen, Qiang Guo, Guoxiang Fu, Mengxue Pan, Liping Liang, Ye Yao, Xiaoxue Gao, Yi Zhou, Zhen Zhang, Xiaoya Xu, Wenhuo Hu, Jianjun Gao, Guoqiang Hua

Stem Cell Reports. 2021 Jan 12; 16(1): 120–133. Published online 2020 Dec 30. doi: 10.1016/j.stemcr.2020.12.005

PMCID:: PMC7897581

Abstract Article PDF–5.0M

Select item 747873117.

BACH2 drives quiescence and maintenance of resting Treg cells to promote homeostasis and cancer immunosuppression

Francis M. Grant, Jie Yang, Rabab Nasrallah, James Clarke, Firas Sadiyah, Sarah K. Whiteside, Charlotte J. Imianowski, Paula Kuo, Panagiota Vardaka, Tihomir Todorov, Nordin Zandhuis, Ilinca Patrascan, David F. Tough, Kohei Kometani, Robert Eil, Tomohiro Kurosaki, Klaus Okkenhaug, Rahul Roychoudhuri

J Exp Med. 2020 Sep 7; 217(9): e20190711. Published online 2020 Jun 9. doi: 10.1084/jem.20190711

PMCID:: PMC7478731

Abstract Article PDF–8.3M

Select item 726367118.

A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators of Pulmonary Metastatic Colonisation

Louise van der Weyden, Agnieszka Swiatkowska, Vivek Iyer, Anneliese O. Speak, David J. Adams

G3 (Bethesda) 2020 Jun; 10(6): 1869–1877. Published online 2020 Apr 3. doi: 10.1534/g3.120.401128

PMCID:: PMC7263671

Abstract Article PDF–1.0M

Select item 695936019.

Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis

Tom Sidwell, Yang Liao, Alexandra L. Garnham, Ajithkumar Vasanthakumar, Renee Gloury, Jonas Blume, Peggy P. Teh, David Chisanga, Christoph Thelemann, Fabian de Labastida Rivera, Christian R. Engwerda, Lynn Corcoran, Kohei Kometani, Tomohiro Kurosaki, Gordon K. Smyth, Wei Shi, Axel Kallies

Nat Commun. 2020; 11: 252. Published online 2020 Jan 14. doi: 10.1038/s41467-019-14112-2

PMCID:: PMC6959360

Abstract Article PDF–3.5M

Select item 690154920.

Bach2 deficiency leads autoreactive B cells to produce IgG autoantibodies and induce lupus through a T cell-dependent extrafollicular pathway

Eunkyeong Jang, Un Kyo Kim, Kiseok Jang, Young Soo Song, Ji-Young Cha, Hansol Yi, Jeehee Youn

Exp Mol Med. 2019 Dec; 51(12): 148. Published online 2019 Dec 9. doi: 10.1038/s12276-019-0352-x

PMCID:: PMC6901549

Abstract Article PDF–3.0M

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