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Select item 111480201.

PPIA dictates NRF2 stability to promote lung cancer progression

Weiqiang Lu, Jiayan Cui, Wanyan Wang, Qian Hu, Yun Xue, Xi Liu, Ting Gong, Yiping Lu, Hui Ma, Xinyu Yang, Bo Feng, Qi Wang, Naixia Zhang, Yechun Xu, Mingyao Liu, Ruth Nussinov, Feixiong Cheng, Hongbin Ji, Jin Huang

Nat Commun. 2024; 15: 4703. Published online 2024 Jun 3. doi: 10.1038/s41467-024-48364-4

PMCID:: PMC11148020

Abstract Article PDF–4.0M

Select item 110723272.

Cyclophilin A associates with and regulates the activity of ZAP70 in TCR/CD3-stimulated T cells

Nikhil Ponnoor Anto, Awadhesh Kumar Arya, Amitha Muraleedharan, Jakeer Shaik, Pulak Ranjan Nath, Etta Livneh, Zuoming Sun, Alex Braiman, Noah Isakov

Cell Mol Life Sci. 2023 Jan; 80(1): 7. Published online 2022 Dec 10. doi: 10.1007/s00018-022-04657-9

PMCID:: PMC11072327

Abstract Article PDF–3.1M

Select item 107999033.

Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly

Emilie Murigneux, Laurent Softic, Corentin Aubé, Carmen Grandi, Delphine Judith, Johanna Bruce, Morgane Le Gall, François Guillonneau, Alain Schmitt, Vincent Parissi, Clarisse Berlioz-Torrent, Laurent Meertens, Maike M. K. Hansen, Sarah Gallois-Montbrun

Nat Commun. 2024; 15: 640. Published online 2024 Jan 20. doi: 10.1038/s41467-024-44958-0

PMCID:: PMC10799903

Abstract Article PDF–25M

Select item 107649584.

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang

Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6

PMCID:: PMC10764958

Abstract Article PDF–4.4M

Select item 106883515.

Emerging role of cyclophilin A in HIV-1 infection: from producer cell to the target cell nucleus

Adrian Padron, Prem Prakash, Jui Pandhare, Jeremy Luban, Chris Aiken, Muthukumar Balasubramaniam, Chandravanu Dash

J Virol. 2023 Nov; 97(11): e00732-23. Published online 2023 Oct 16. doi: 10.1128/jvi.00732-23

PMCID:: PMC10688351

Abstract Article PDF–801K

Select item 106259876.

Bioinformatics analysis and experimental validation of tumorigenic role of PPIA in gastric cancer

Jichao Liu, Yanjun Wang, Zhiwei Zhao, Yanhui Ge

Sci Rep. 2023; 13: 19116. Published online 2023 Nov 5. doi: 10.1038/s41598-023-46508-y

PMCID:: PMC10625987

Abstract Article PDF–9.6M

Select item 106176737.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 105313138.

New Insights into Dyskerin-CypA Interaction: Implications for X-Linked Dyskeratosis Congenita and Beyond

Valentina Belli, Daniela Maiello, Concetta Di Lorenzo, Maria Furia, Rosario Vicidomini, Mimmo Turano

Genes (Basel) 2023 Sep; 14(9): 1766. Published online 2023 Sep 6. doi: 10.3390/genes14091766

PMCID:: PMC10531313

Abstract Article PDF–2.5M

Select item 104472399.

TRIM5α restricts poxviruses and is antagonized by CypA and the viral protein C6

Yiqi Zhao, Yongxu Lu, Samuel Richardson, Meghna Sreekumar, Jonas D. Albarnaz, Geoffrey L. Smith

Nature. 2023; 620(7975): 873–880. Published online 2023 Aug 9. doi: 10.1038/s41586-023-06401-0

PMCID:: PMC10447239

Abstract Article PDF–10M

Select item 1028411710.

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry

Fenglong Jiao, Leah J. Salituro, Clinton Yu, Craig B. Gutierrez, Scott D. Rychnovsky, Lan Huang

Anal Chem. Author manuscript; available in PMC 2023 Jun 21.

Published in final edited form as: Anal Chem. 2023 Jan 31; 95(4): 2532–2539. Published online 2023 Jan 18. doi: 10.1021/acs.analchem.2c04986

PMCID:: PMC10284117

Abstract Article PDF–2.5M

Select item 1023742211.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1015161512.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 1013893113.

Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage

Sanna Abbasi, Laila Bayat, Caroline Schild-Poulter

Int J Mol Sci. 2023 Apr; 24(8): 7041. Published online 2023 Apr 11. doi: 10.3390/ijms24087041

PMCID:: PMC10138931

Abstract Article PDF–4.0M

Select item 1013488914.

A Tripartite Complex HIV-1 Tat-Cyclophilin A-Capsid Protein Enables Tat Encapsidation That Is Required for HIV-1 Infectivity

Malvina Schatz, Laetitia Marty, Camille Ounadjela, Phuoc Bao Viet Tong, Ilaria Cardace, Clément Mettling, Pierre-Emmanuel Milhiet, Luca Costa, Cédric Godefroy, Martine Pugnière, Jean-François Guichou, Jean-Michel Mesnard, Mickaël Blaise, Bruno Beaumelle

J Virol. 2023 Apr; 97(4): e00278-23. Published online 2023 Apr 11. doi: 10.1128/jvi.00278-23

PMCID:: PMC10134889

Abstract Article PDF–1.3M

Select item 1001945115.

Molecular insight into the specific interactions of the SARS‐Coronavirus‐2 nucleocapsid with RNA and host protein

Eunjeong Lee, Jasmina S. Redzic, Anthony J. Saviola, Xueni Li, Christopher C. Ebmeier, Tatiana Kutateladze, Kirk Charles Hansen, Rui Zhao, Natalie Ahn, Nikolai N. Sluchanko, Elan Eisenmesser

Protein Sci. 2023 Apr; 32(4): e4603. Published online 2023 Apr 1. doi: 10.1002/pro.4603

PMCID:: PMC10019451

Abstract Article PDF–5.5M

Select item 995044716.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 987484017.

Cyclophilin A‐mediated mitigation of coronavirus SARS‐CoV‐2

Simranjeet Singh Sekhon, Woo‐Ri Shin, Sang Yong Kim, Dong‐Seok Jeong, Wooil Choi, Bong‐Keun Choi, Jiho Min, Ji‐Young Ahn, Yang‐Hoon Kim

Bioeng Transl Med. 2023 Mar; 8(2): e10436. Published online 2022 Oct 27. doi: 10.1002/btm2.10436

PMCID:: PMC9874840

Abstract Article PDF–6.6M

Select item 979798818.

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel

J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144

PMCID:: PMC9797988

Abstract Article PDF–6.9M

Select item 973393719.

Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia

Qi Jin, Blanca Gutierrez Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, Igor Fijalkwoski, Cristina Borin, Jolien Van Laere, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, George Yacu, Wouter Von Loocke, Giuseppe Basso, Giulia Veltri, Ingrid Dreveny, Issam Ben-Sahra, Young Ah Goo, Stephanie L. Safgren, Yi-Chien Tsai, Beat Bornhauser, Praveen Kumar Suraneni, Alexandre Gaspar-Maia, Irawati Kandela, Pieter Van Vlierberghe, John D. Crispino, Aristotelis Tsirigos, Panagiotis Ntziachristos

Sci Adv. 2022 Dec; 8(49): eabq8437. Published online 2022 Dec 9. doi: 10.1126/sciadv.abq8437

PMCID:: PMC9733937

Abstract Article PDF–2.2M

Select item 970808620.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676

PMCID:: PMC9708086

Abstract Article PDF–8.5M

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