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Select item 105319031.

Functional Insight into and Refinement of the Genomic Boundaries of the JARID2-Neurodevelopmental Disorder Episignature

Liselot van der Laan, Kathleen Rooney, Sadegheh Haghshenas, Ananília Silva, Haley McConkey, Raissa Relator, Michael A. Levy, Irene Valenzuela, Laura Trujillano, Amaia Lasa-Aranzasti, Berta Campos, Neus Castells, Eline A. Verberne, Saskia Maas, Mariëlle Alders, Marcel M. A. M. Mannens, Mieke M. van Haelst, Bekim Sadikovic, Peter Henneman

Int J Mol Sci. 2023 Sep; 24(18): 14240. Published online 2023 Sep 18. doi: 10.3390/ijms241814240

PMCID:: PMC10531903

Abstract Article PDF–3.6M

Select item 97244042.

The LINC00852/miR-29a-3p/JARID2 axis regulates the proliferation and invasion of prostate cancer cell

Hao Zhang, Yang Du, Peng Xin, Xiaojun Man

BMC Cancer. 2022; 22: 1269. Published online 2022 Dec 5. doi: 10.1186/s12885-022-10263-6

PMCID:: PMC9724404

Abstract Article PDF–7.3M

Select item 90405563.

A protein interaction landscape of breast cancer

Minkyu Kim, Jisoo Park, Mehdi Bouhaddou, Kyumin Kim, Ajda Rojc, Maya Modak, Margaret Soucheray, Michael J. McGregor, Patrick O’Leary, Denise Wolf, Erica Stevenson, Tzeh Keong Foo, Dominique Mitchell, Kari A. Herrington, Denise P. Muñoz, Beril Tutuncuoglu, Kuei-Ho Chen, Fan Zheng, Jason F. Kreisberg, Morgan E. Diolaiti, John D. Gordan, Jean-Philippe Coppé, Danielle L. Swaney, Bing Xia, Laura van ’t Veer, Alan Ashworth, Trey Ideker, Nevan Krogan

Science. Author manuscript; available in PMC 2022 Apr 26.

Published in final edited form as: Science. 2021 Oct; 374(6563): eabf3066. Published online 2021 Oct 1. doi: 10.1126/science.abf3066

PMCID:: PMC9040556

Abstract Article PDF–2.2M

Select item 83641814.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 81972875.

An RNAi Screening of Clinically Relevant Transcription Factors Regulating Human Adipogenesis and Adipocyte Metabolism

Christel Björk, Narmadha Subramanian, Jianping Liu, Juan Ramon Acosta, Beatriz Tavira, Anders B Eriksson, Peter Arner, Jurga Laurencikiene

Endocrinology. 2021 Jul; 162(7): bqab096. Published online 2021 May 7. doi: 10.1210/endocr/bqab096

PMCID:: PMC8197287

Abstract Article

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79936307.

JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications

Vignesh Kasinath, Curtis Beck, Paul Sauer, Simon Poepsel, Jennifer Kosmatka, Marco Faini, Daniel Toso, Ruedi Aebersold, Eva Nogales

Science. Author manuscript; available in PMC 2021 Jul 22.

Published in final edited form as: Science. 2021 Jan 22; 371(6527): eabc3393. doi: 10.1126/science.abc3393

PMCID:: PMC7993630

Abstract Article PDF–2.7M

Select item 78411538.

Reduced Expression of Jumonji AT-Rich Interactive Domain 2 (JARID2) in Glioma Inhibits Tumor Growth In Vitro and In Vivo

Zhenjiang Li, Chenyang Xu, Ming Gao, Bingqian Ding, Xinting Wei, Nan Ji

Oncol Res. 2017; 25(3): 365–372. Published online 2017 Mar 13. doi: 10.3727/096504016X14738135889976

PMCID:: PMC7841153

Abstract Article PDF–6.1M

Select item 67468229.

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei

Giovanni Nassa, Giorgio Giurato, Annamaria Salvati, Valerio Gigantino, Giovanni Pecoraro, Jessica Lamberti, Francesca Rizzo, Tuula A. Nyman, Roberta Tarallo, Alessandro Weisz

Sci Data. 2019; 6: 173. Published online 2019 Sep 16. doi: 10.1038/s41597-019-0179-2

PMCID:: PMC6746822

Abstract Article PDF–2.0M

Select item 660921110.

CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism

Andrea Piunti, Edwin R. Smith, Marc A. J. Morgan, Michal Ugarenko, Natalia Khaltyan, Kathryn A. Helmin, Caila A. Ryan, David C. Murray, Ryan A. Rickels, Bahar D. Yilmaz, Emily J. Rendleman, Jeffrey N. Savas, Benjamin D. Singer, Serdar E. Bulun, Ali Shilatifard

Sci Adv. 2019 Jul; 5(7): eaax2887. Published online 2019 Jul 3. doi: 10.1126/sciadv.aax2887

PMCID:: PMC6609211

Abstract Article PDF–1.1M

Select item 658119711.

Gain of additional BIRC3 protein functions through 3′UTR-mediated protein complex formation

Shih-Han Lee, Christine Mayr

Mol Cell. Author manuscript; available in PMC 2020 May 16.

Published in final edited form as: Mol Cell. 2019 May 16; 74(4): 701–712.e9. Published online 2019 Apr 1. doi: 10.1016/j.molcel.2019.03.006

PMCID:: PMC6581197

Abstract Article PDF–2.0M

Select item 635615812.

A novel form of JARID2 is required for differentiation in lineage‐committed cells

Diaa Al‐Raawi, Rhian Jones, Susanne Wijesinghe, John Halsall, Marija Petric, Sally Roberts, Neil A Hotchin, Aditi Kanhere

EMBO J. 2019 Feb 1; 38(3): e98449. Published online 2018 Dec 20. doi: 10.15252/embj.201798449

PMCID:: PMC6356158

Abstract Article PDF–1.3M

Select item 623710013.

JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells

Hamza Celik, Won Kyun Koh, Ashley C. Kramer, Elizabeth L. Ostrander, Cates Mallaney, Daniel A.C. Fisher, Jingyu Xiang, William C. Wilson, Andrew Martens, Alok Kothari, Gregory Fishberger, Eric Tycksen, Darja Karpova, Eric J. Duncavage, Youngsook Lee, Stephen T. Oh, Grant A. Challen

Cancer Cell. Author manuscript; available in PMC 2019 Nov 12.

Published in final edited form as: Cancer Cell. 2018 Nov 12; 34(5): 741–756.e8. doi: 10.1016/j.ccell.2018.10.008

PMCID:: PMC6237100

Abstract Article PDF–4.3M

Select item 582692614.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 563877015.

Comparative Interactomes of VRK1 and VRK3 with Their Distinct Roles in the Cell Cycle of Liver Cancer

Namgyu Lee, Dae-Kyum Kim, Seung Hyun Han, Hye Guk Ryu, Sung Jin Park, Kyong-Tai Kim, Kwan Yong Choi

Mol Cells. 2017 Sep 30; 40(9): 621–631. Published online 2017 Sep 20. doi: 10.14348/molcells.2017.0108

PMCID:: PMC5638770

Abstract Article PDF–2.9M

Select item 553161116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 542186417.

Jarid2 is essential for the maintenance of tumor initiating cells in bladder cancer

Xin-Xing Zhu, Ya-Wei Yan, Chun-Zhi Ai, Shan Jiang, Shan-Shan Xu, Min Niu, Xiang-Zhen Wang, Gen-Shen Zhong, Xi-Feng Lu, Yu Xue, Shaoqi Tian, Guangyao Li, Shaojun Tang, Yi-Zhou Jiang

Oncotarget. 2017 Apr 11; 8(15): 24483–24490. Published online 2017 Feb 20. doi: 10.18632/oncotarget.15522

PMCID:: PMC5421864

Abstract Article PDF–14M

Select item 522162318.

Chromatin association of XRCC5/6 in the absence of DNA damage depends on the XPE gene product DDB2

Damiano Fantini, Shuo Huang, John M. Asara, Srilata Bagchi, Pradip Raychaudhuri

Mol Biol Cell. 2017 Jan 1; 28(1): 192–200. doi: 10.1091/mbc.E16-08-0573

PMCID:: PMC5221623

Abstract Article PDF–1.7M

Select item 515702319.

Interactomic analysis of REST/NRSF and implications of its functional links with the transcription suppressor TRIM28 during neuronal differentiation

Namgyu Lee, Sung Jin Park, Ghazal Haddad, Dae-Kyum Kim, Seon-Min Park, Sang Ki Park, Kwan Yong Choi

Sci Rep. 2016; 6: 39049. Published online 2016 Dec 15. doi: 10.1038/srep39049

PMCID:: PMC5157023

Abstract Article PDF–2.0M

Select item 513000720.

JARID2 promotes invasion and metastasis of hepatocellular carcinoma by facilitating epithelial-mesenchymal transition through PTEN/AKT signaling

Xiong Lei, Jiang-Feng Xu, Rui-Min Chang, Feng Fang, Chao-Hui Zuo, Lian-Yue Yang

Oncotarget. 2016 Jun 28; 7(26): 40266–40284. Published online 2016 May 31. doi: 10.18632/oncotarget.9733

PMCID:: PMC5130007

Abstract Article PDF–14M

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