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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 70697202.

Etv transcription factors functionally diverge from their upstream FGF signaling in lens development

Ankur Garg, Abdul Hannan, Qian Wang, Neoklis Makrides, Jian Zhong, Hongge Li, Sungtae Yoon, Yingyu Mao, Xin Zhang

eLife. 2020; 9: e51915. Published online 2020 Feb 11. doi: 10.7554/eLife.51915

PMCID:: PMC7069720

Abstract Article PDF–6.3M

Select item 69362573.

Transcriptomic analysis and novel insights into lens fibre cell differentiation regulated by Gata3

Elena Martynova, Yilin Zhao, Qing Xie, Deyou Zheng, Ales Cvekl

Open Biol. 2019 Dec; 9(12): 190220. Published online 2019 Dec 18. doi: 10.1098/rsob.190220

PMCID:: PMC6936257

Abstract Article PDF–1.9M

Select item 64595104.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 61099185.

Transcriptional burst fraction and size dynamics during lens fiber cell differentiation and detailed insights into the denucleation process

Saima Limi, Adrien Senecal, Robert Coleman, Melissa Lopez-Jones, Peng Guo, Christina Polumbo, Robert H. Singer, Arthur I. Skoultchi, Ales Cvekl

J Biol Chem. 2018 Aug 24; 293(34): 13176–13190. Published online 2018 Jun 29. doi: 10.1074/jbc.RA118.001927

PMCID:: PMC6109918

Abstract Article PDF–4.1M

Select item 52958216.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 50252457.

Disruption of Rest Leads to the Early Onset of Cataracts with the Aberrant Terminal Differentiation of Lens Fiber Cells

Hitomi Aoki, Hajime Ogino, Hiroyuki Tomita, Akira Hara, Takahiro Kunisada

PLoS One. 2016; 11(9): e0163042. Published online 2016 Sep 15. doi: 10.1371/journal.pone.0163042

PMCID:: PMC5025245

Abstract Article PDF–4.2M

Select item 49814198.

A γA-Crystallin Mouse Mutant Secc with Small Eye, Cataract and Closed Eyelid

Man Hei Cheng, Chung Nga Tam, Kwong Wai Choy, Wai Hung Tsang, Sze Lan Tsang, Chi Pui Pang, You Qiang Song, Mai Har Sham

PLoS One. 2016; 11(8): e0160691. Published online 2016 Aug 11. doi: 10.1371/journal.pone.0160691

PMCID:: PMC4981419

Abstract Article PDF–17M

Select item 43597399.

Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development

Roel Quintens, Tine Verreet, Ann Janssen, Mieke Neefs, Liselotte Leysen, Arlette Michaux, Mieke Verslegers, Nada Samari, Giuseppe Pani, Joris Verheyde, Sarah Baatout, Mohammed A. Benotmane

Biol Open. 2015 Mar 15; 4(3): 331–344. Published online 2015 Feb 13. doi: 10.1242/bio.20149969

PMCID:: PMC4359739

Abstract Article PDF–1.3M

Select item 421018310.

Expression of Truncated PITX3 in the Developing Lens Leads to Microphthalmia and Aphakia in Mice

Kenta Wada, Yoshibumi Matsushima, Tomoki Tada, Sayaka Hasegawa, Yo Obara, Yasuhiro Yoshizawa, Gou Takahashi, Hiroshi Hiai, Midori Shimanuki, Sari Suzuki, Junichi Saitou, Naoki Yamamoto, Masumi Ichikawa, Kei Watanabe, Yoshiaki Kikkawa

PLoS One. 2014; 9(10): e111432. Published online 2014 Oct 27. doi: 10.1371/journal.pone.0111432

PMCID:: PMC4210183

Abstract Article PDF–12M

Select item 357241011.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 340850612.

Transcription factor GATA-3 is essential for lens development

Atsuko Maeda, Takashi Moriguchi, Michito Hamada, Manabu Kusakabe, Yuki Fujioka, Takako Nakano, Keigyou Yoh, Kim-Chew Lim, James Douglas Engel, Satoru Takahashi

Dev Dyn. Author manuscript; available in PMC 2012 Jul 30.

Published in final edited form as: Dev Dyn. 2009 Sep; 238(9): 2280–2291. doi: 10.1002/dvdy.22035

PMCID:: PMC3408506

Abstract Article PDF–4.9M

Select item 323483613.

The Orchestration of Mammalian Tissue Morphogenesis through a Series of Coherent Feed-forward Loops

Qing Xie, Ales Cvekl

J Biol Chem. 2011 Dec 16; 286(50): 43259–43271. Published online 2011 Oct 13. doi: 10.1074/jbc.M111.264580

PMCID:: PMC3234836

Abstract Article PDF–3.9M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253415.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 297803916.

Pitx3 controls multiple aspects of lens development

Olga Medina-Martinez, Rina Shah, Milan Jamrich

Dev Dyn. Author manuscript; available in PMC 2010 Nov 10.

Published in final edited form as: Dev Dyn. 2009 Sep; 238(9): 2193–2201. doi: 10.1002/dvdy.21924

PMCID:: PMC2978039

Abstract Article PDF–2.3M

Select item 189911617.

A novel view of the transcriptome revealed from gene trapping in mouse embryonic stem cells

Guglielmo Roma, Gilda Cobellis, Pamela Claudiani, Francesco Maione, Pedro Cruz, Gaetano Tripoli, Marco Sardiello, Ivana Peluso, Elia Stupka

Genome Res. 2007 Jul; 17(7): 1051–1060. doi: 10.1101/gr.5720807

PMCID:: PMC1899116

Abstract Article PDF–739K

Select item 52892818.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

Select item 52439919.

HSF4 is required for normal cell growth and differentiation during mouse lens development

Mitsuaki Fujimoto, Hanae Izu, Keisuke Seki, Ken Fukuda, Teruo Nishida, Shu-ichi Yamada, Kanefusa Kato, Shigenobu Yonemura, Sachiye Inouye, Akira Nakai

EMBO J. 2004 Oct 27; 23(21): 4297–4306. Published online 2004 Oct 14. doi: 10.1038/sj.emboj.7600435

PMCID:: PMC524399

Abstract Article PDF–399K

Select item 39223220.

Gamma-crystallin family of the mouse lens: structural and evolutionary relationships.

M L Breitman, S Lok, G Wistow, J Piatigorsky, J A Tréton, R J Gold, L C Tsui

Proc Natl Acad Sci U S A. 1984 Dec; 81(24): 7762–7766. doi: 10.1073/pnas.81.24.7762

PMCID:: PMC392232

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