PMC Links for GEO Profiles (Select 87121758) - PMC

Select item 92744971.

CCDC65, a Gene Knockout that leads to Early Death of Mice, acts as a potentially Novel Tumor Suppressor in Lung Adenocarcinoma

Ziyan Zhang, Ping Xu, Zhe Hu, Zhaojian Fu, Tongyuan Deng, Xiaojie Deng, Lanzhu Peng, Yingying Xie, Lingzhi Long, Dayong Zheng, Peng Shen, Mengmin Zhang, Bin Gong, Zhibo Zhu, Junhao Lin, Rui Chen, Zhen Liu, Huilin Yang, Rong Li, Weiyi Fang

Int J Biol Sci. 2022; 18(10): 4171–4186. Published online 2022 Jun 27. doi: 10.7150/ijbs.69332

PMCID:: PMC9274497

Abstract Article PDF–3.3M

Select item 91063032.

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors

Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen

Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638

PMCID:: PMC9106303

Abstract Article PDF–918K

Select item 85226393.

Loss of DRC1 function leads to multiple morphological abnormalities of the sperm flagella and male infertility in human and mouse

Jintao Zhang, Xiaojin He, Huan Wu, Xin Zhang, Shenmin Yang, Chunyu Liu, Siyu Liu, Rong Hua, Shushu Zhou, Shuqin Zhao, Fan Hu, Junqiang Zhang, Wangjie Liu, Huiru Cheng, Yang Gao, Feng Zhang, Yunxia Cao, Mingxi Liu

Hum Mol Genet. 2021 Nov 1; 30(21): 1996–2011. Published online 2021 Jun 24. doi: 10.1093/hmg/ddab171

PMCID:: PMC8522639

Abstract Article PDF–3.2M

Select item 83641814.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 83150525.

CCDC65 as a new potential tumor suppressor induced by metformin inhibits activation of AKT1 via ubiquitination of ENO1 in gastric cancer

Tongyuan Deng, Peng Shen, Aimin Li, Ziyan Zhang, Huiling Yang, Xiaojie Deng, Xuemei Peng, Zhe Hu, Zibo Tang, Jiahao Liu, Rentao Hou, Zhen Liu, Weiyi Fang

Theranostics. 2021; 11(16): 8112–8128. Published online 2021 Jul 13. doi: 10.7150/thno.54961

PMCID:: PMC8315052

Abstract Article PDF–4.7M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 61666827.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 57521358.

Evolutionary proteomics uncovers ancient associations of cilia with signaling pathways

Monika Abedin Sigg, Tabea Menchen, Chanjae Lee, Jeffery Johnson, Melissa K. Jungnickel, Semil P. Choksi, Galo Garcia, 3rd, Henriette Busengdal, Gerard Dougherty, Petra Pennekamp, Claudius Werner, Fabian Rentzsch, Harvey M. Florman, Nevan Krogan, John B. Wallingford, Heymut Omran, Jeremy F. Reiter

Dev Cell. Author manuscript; available in PMC 2018 Dec 18.

Published in final edited form as: Dev Cell. 2017 Dec 18; 43(6): 744–762.e11. doi: 10.1016/j.devcel.2017.11.014

PMCID:: PMC5752135

Abstract Article PDF–1.4M

Select item 55316119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 379126410.

Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia

Christina Austin-Tse, Jan Halbritter, Maimoona A. Zariwala, Renée M. Gilberti, Heon Yung Gee, Nathan Hellman, Narendra Pathak, Yan Liu, Jennifer R. Panizzi, Ramila S. Patel-King, Douglas Tritschler, Raqual Bower, Eileen O’Toole, Jonathan D. Porath, Toby W. Hurd, Moumita Chaki, Katrina A. Diaz, Stefan Kohl, Svjetlana Lovric, Daw-Yang Hwang, Daniela A. Braun, Markus Schueler, Rannar Airik, Edgar A. Otto, Margaret W. Leigh, Peadar G. Noone, Johnny L. Carson, Stephanie D. Davis, Jessica E. Pittman, Thomas W. Ferkol, Jeffry J. Atkinson, Kenneth N. Olivier, Scott D. Sagel, Sharon D. Dell, Margaret Rosenfeld, Carlos E. Milla, Niki T. Loges, Heymut Omran, Mary E. Porter, Stephen M. King, Michael R. Knowles, Iain A. Drummond, Friedhelm Hildebrandt

Am J Hum Genet. 2013 Oct 3; 93(4): 672–686. doi: 10.1016/j.ajhg.2013.08.015

PMCID:: PMC3791264

Abstract Article PDF–2.5M

Select item 375330211.

CCDC65 Mutation Causes Primary Ciliary Dyskinesia with Normal Ultrastructure and Hyperkinetic Cilia

Amjad Horani, Steven L. Brody, Thomas W. Ferkol, David Shoseyov, Mollie G. Wasserman, Asaf Ta-shma, Kate S. Wilson, Philip V. Bayly, Israel Amirav, Malena Cohen-Cymberknoh, Susan K. Dutcher, Orly Elpeleg, Eitan Kerem

PLoS One. 2013; 8(8): e72299. Published online 2013 Aug 26. doi: 10.1371/journal.pone.0072299

PMCID:: PMC3753302

Abstract Article PDF–3.4M

Select item 319072512.

Building Blocks of the Nexin-Dynein Regulatory Complex in Chlamydomonas Flagella

Jianfeng Lin, Douglas Tritschler, Kangkang Song, Cynthia F. Barber, Jennifer S. Cobb, Mary E. Porter, Daniela Nicastro

J Biol Chem. 2011 Aug 19; 286(33): 29175–29191. Published online 2011 Jun 23. doi: 10.1074/jbc.M111.241760

PMCID:: PMC3190725

Abstract Article PDF–4.5M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 135612914.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

Select item 13924115.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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