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Items: 1 to 20 of 131

1.
FOXO1 regulates RUNX2 ubiquitination through SMURF2 in calcific aortic valve disease
Chen Jiang, Dingyi Yao, Zongtao Liu, Yidan Zheng, Ming Chen, Wai Yen Yim, Qiang Zheng, Tailong Zhang, Lin Fan, Zhengfeng Fan, Bingchuan Geng, Rui Tian, Tingwen Zhou, Weihua Qiao, Jiawei Shi, Fei Li, Li Xu, Yuming Huang, Nianguo Dong
Redox Biol. 2024 Jul; 73: 103215. Published online 2024 May 27. doi: 10.1016/j.redox.2024.103215
PMCID:
PMC11167395
AbstractArticlePDF–24M
2.
The E3 ubiquitin ligase SMURF2 stabilizes RNA editase ADAR1p110 and promotes its adenosine-to-inosine (A-to-I) editing function
Praveen Koganti, Venkata Narasimha Kadali, Dhanoop Manikoth Ayyathan, Andrea Emanuelli, Biagio Paolini, Gal Levy-Cohen, Michael Blank
Cell Mol Life Sci. 2022 May; 79(5): 237. Published online 2022 Apr 11. doi: 10.1007/s00018-022-04272-8
PMCID:
PMC11072456
AbstractArticlePDF–6.5M
3.
Loss of SMURF2 expression enhances RACK1 stability and promotes ovarian cancer progression
Yanan Pi, Qiushi Feng, Fusheng Sun, Zhiqiang Wang, Yue Zhao, Dejia Chen, Yiming Liu, Ge Lou
Cell Death Differ. 2023 Nov; 30(11): 2382–2392. Published online 2023 Oct 12. doi: 10.1038/s41418-023-01226-w
PMCID:
PMC10657365
AbstractArticlePDF–4.0M
4.
Flavin containing monooxygenase 2 regulates renal tubular cell fibrosis and paracrine secretion via SMURF2 in AKI-CKD transformation
Longfei Wang, Hongchu Zha, Jing Huang, Lang Shi
Int J Mol Med. 2023 Nov; 52(5): 110. Published online 2023 Oct 4. doi: 10.3892/ijmm.2023.5313
PMCID:
PMC10558214
AbstractArticlePDF–1.5M
5.
Smurf1 and Smurf2 mediated polyubiquitination and degradation of RNF220 suppresses Shh-group medulloblastoma
Yuwei Li, Huishan Wang, Bin Sun, Guifeng Su, Yu Cang, Ling Zhao, Shuhua Zhao, Yan Li, Bingyu Mao, Pengcheng Ma
Cell Death Dis. 2023 Aug; 14(8): 494. Published online 2023 Aug 3. doi: 10.1038/s41419-023-06025-2
PMCID:
PMC10400574
AbstractArticlePDF–6.3M
6.
SMURF2 facilitates ubiquitin-mediated degradation of ID2 to attenuate lung cancer cell proliferation
Mingwei Han, Yixiao Guo, Yiming Li, Qingmei Zeng, Wanwan Zhu, Jianli Jiang
Int J Biol Sci. 2023; 19(11): 3324–3340. Published online 2023 Jun 26. doi: 10.7150/ijbs.80979
PMCID:
PMC10367561
AbstractArticlePDF–8.8M
7.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
8.
LncRNA LITATS1 suppresses TGF‐β‐induced EMT and cancer cell plasticity by potentiating TβRI degradation
Chuannan Fan, Qian Wang, Thomas B Kuipers, Davy Cats, Prasanna Vasudevan Iyengar, Sophie C Hagenaars, Wilma E Mesker, Peter Devilee, Rob A E M Tollenaar, Hailiang Mei, Peter ten Dijke
EMBO J. 2023 May; 42(10): e112806. Published online 2023 Mar 30. doi: 10.15252/embj.2022112806
PMCID:
PMC10183827
AbstractArticlePDF–5.6M
9.
Cytoplasmic YAP1‐mediated ESCRT‐III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer
Yan Guo, Yuqing Cui, Yangyang Li, Xiaoying Jin, Dandan Wang, Mengxia Lei, Fengzhi Chen, Yali Liu, Jinwen Xu, Guanyu Yao, Guangchun Zeng, Xuesong Chen
Cancer Commun (Lond) 2023 May; 43(5): 582–612. Published online 2023 Apr 2. doi: 10.1002/cac2.12417
PMCID:
PMC10174091
AbstractArticlePDF–22M
10.
The E3 ligase subunit FBXO45 binds the interferon-λ receptor and promotes its degradation during influenza virus infection
MuChun Tsai, Wissam Osman, Jessica Adair, Rabab ElMergawy, Lexie Chafin, Finny Johns, Daniela Farkas, Ajit Elhance, James Londino, Rama K. Mallampalli
J Biol Chem. 2022 Dec; 298(12): 102698. Published online 2022 Nov 13. doi: 10.1016/j.jbc.2022.102698
PMCID:
PMC9747586
AbstractArticlePDF–2.6M
11.
Deubiquitinase USP35 stabilizes BRPF1 to activate mevalonate (MVA) metabolism during prostate tumorigenesis
Guowen Lin, Tianrun Huang, Xiaobo Zhang, Gangmin Wang
Cell Death Discov. 2022; 8: 453. Published online 2022 Nov 10. doi: 10.1038/s41420-022-01231-x
PMCID:
PMC9649703
AbstractArticlePDF–6.3M
12.
TRAF4 hyperactivates HER2 signaling and contributes to Trastuzumab resistance in HER2-positive breast cancer
Yayun Gu, Huanyao Gao, Huan Zhang, August John, Xiujuan Zhu, Suganti Shivaram, Jia Yu, Richard M. Weinshilboum, Liewei Wang
Oncogene. 2022; 41(35): 4119–4129. Published online 2022 Jul 21. doi: 10.1038/s41388-022-02415-6
PMCID:
PMC9417995
AbstractArticlePDF–3.6M
13.
Phosphorylation of SMURF2 by ATM exerts a negative feedback control of DNA damage response
Liu-Ya Tang, Adam Thomas, Ming Zhou, Ying E. Zhang
J Biol Chem. 2020 Dec 25; 295(52): 18485–18493. Published online 2021 Jan 13. doi: 10.1074/jbc.RA120.014179
PMCID:
PMC9350827
AbstractArticlePDF–2.1M
14.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
15.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
16.
TRAF4 Inhibits the Apoptosis and Promotes the Proliferation of Breast Cancer Cells by Inhibiting the Ubiquitination of Spindle Assembly-Associated Protein Eg5
Miaomiao Hao, Jie Zhang, Mingfang Sun, Kexin Diao, Jian Wang, Shiping Li, Qixue Cao, Shundong Dai, Xiaoyi Mi
Front Oncol. 2022; 12: 855139. Published online 2022 May 25. doi: 10.3389/fonc.2022.855139
PMCID:
PMC9174544
AbstractArticlePDF–14M
17.
CBX3 Regulated By YBX1 Promotes Smoking-induced Pancreatic Cancer Progression via Inhibiting SMURF2 Expression
Huan Zhang, Haixin Yu, Dianyuan Ren, Yan Sun, Feng Guo, Hongkun Cai, Chen Zhou, Yingke Zhou, Xin Jin, Heshui Wu
Int J Biol Sci. 2022; 18(8): 3484–3497. Published online 2022 May 13. doi: 10.7150/ijbs.68995
PMCID:
PMC9134897
AbstractArticlePDF–4.2M
18.
The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside
Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang
J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009
PMCID:
PMC9058836
AbstractArticlePDF–2.9M
19.
The Emerging Role of E3 Ubiquitin Ligase SMURF2 in the Regulation of Transcriptional Co-Repressor KAP1 in Untransformed and Cancer Cells and Tissues
Pooja Anil Shah, Sandy Boutros-Suleiman, Andrea Emanuelli, Biagio Paolini, Gal Levy-Cohen, Michael Blank
Cancers (Basel) 2022 Apr; 14(7): 1607. Published online 2022 Mar 22. doi: 10.3390/cancers14071607
PMCID:
PMC8997158
AbstractArticlePDF–4.6M
20.
Smurf2-induced degradation of SMAD2 causes inhibition of hair follicle stem cell differentiation
Bojie Lin, Dan Huang, Guanyu Lin, Yong Miao, Jin Wang, Zhexiang Fan, Zhiqi Hu
Cell Death Discov. 2022; 8: 160. Published online 2022 Apr 4. doi: 10.1038/s41420-022-00920-x
PMCID:
PMC8980066
AbstractArticlePDF–3.1M

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