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Items: 1 to 20 of 55

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
3.
Clustering of phosphatase RPTPα promotes Src signaling and the arthritogenic action of synovial fibroblasts
Sho Sendo, William B. Kiosses, Shen Yang, Dennis J. Wu, Daniel W. K. Lee, Lin Liu, Yael Aschner, Allison J. Vela, Gregory P. Downey, Eugenio Santelli, Nunzio Bottini
Sci Signal. Author manuscript; available in PMC 2024 Jul 4.
Published in final edited form as: Sci Signal. 2023 Jul 4; 16(792): eabn8668. Published online 2023 Jul 4. doi: 10.1126/scisignal.abn8668
PMCID:
PMC10544828
AbstractArticlePDF–3.8M
4.
PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805
Yunpeng Bai, Guimei Yu, Hong-Ming Zhou, Ovini Amarasinghe, Yuan Zhou, Peipei Zhu, Qinglin Li, Lujuan Zhang, Frederick Nguele Meke, Yiming Miao, Eli Chapman, W. Andy Tao, Zhong-Yin Zhang
Autophagy. 2023; 19(5): 1562–1581. Published online 2022 Nov 7. doi: 10.1080/15548627.2022.2140558
PMCID:
PMC10240998
AbstractArticlePDF–4.4M
5.
PTPα promotes fibroproliferative responses after acute lung injury
Yael Aschner, Kelly A. Correll, Keriann M. Beke, Daniel G. Foster, Helen M. Roybal, Meghan R. Nelson, Carly L. Meador, Matthew Strand, Kelsey C. Anderson, Camille M. Moore, Paul R. Reynolds, Katrina W. Kopf, Ellen L. Burnham, Gregory P. Downey
Am J Physiol Lung Cell Mol Physiol. 2022 Jul 1; 323(1): L69–L83. Published online 2022 Jun 7. doi: 10.1152/ajplung.00436.2021
PMCID:
PMC9255711
AbstractArticle
6.
Transcriptional profiling of mESC-derived tendon and fibrocartilage cell fate switch
Deepak A. Kaji, Angela M. Montero, Roosheel Patel, Alice H. Huang
Nat Commun. 2021; 12: 4208. Published online 2021 Jul 9. doi: 10.1038/s41467-021-24535-5
PMCID:
PMC8270956
AbstractArticlePDF–4.7M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
Protein tyrosine phosphatase-α amplifies transforming growth factor-β-dependent profibrotic signaling in lung fibroblasts
Yael Aschner, Meghan Nelson, Matthew Brenner, Helen Roybal, Keriann Beke, Carly Meador, Daniel Foster, Kelly A. Correll, Paul R. Reynolds, Kelsey Anderson, Elizabeth F. Redente, Jennifer Matsuda, David W. H. Riches, Steve D. Groshong, Ambra Pozzi, Jan Sap, Qin Wang, Dhaarmini Rajshankar, Christopher A. G. McCulloch, Rachel L. Zemans, Gregory P. Downey
Am J Physiol Lung Cell Mol Physiol. 2020 Aug 1; 319(2): L294–L311. Published online 2020 Jun 3. doi: 10.1152/ajplung.00235.2019
PMCID:
PMC7473933
AbstractArticle
9.
Mitotic Activation of Protein-tyrosine Phosphatase α and Regulation of Its Src-mediated Transforming Activity by Its Sites of Protein Kinase C Phosphorylation
Xin-Min Zheng, Ross J. Resnick, David Shalloway
J Biol Chem. Author manuscript; available in PMC 2017 Oct 15.
Published in final edited form as: J Biol Chem. 2002 Jun 14; 277(24): 21922–21929. Published online 2002 Mar 28. doi: 10.1074/jbc.M201394200
PMCID:
PMC5641391
AbstractArticlePDF–3.9M
10.
Extracellular domain dependence of PTPα transforming activity
Barbara Tremper-Wells, Ross J. Resnick, Xinmin Zheng, Leslie J. Holsinger, David Shalloway
Genes Cells. Author manuscript; available in PMC 2016 May 23.
Published in final edited form as: Genes Cells. 2010 Jun; 15(7): 711–724. Published online 2010 Jun 7. doi: 10.1111/j.1365-2443.2010.01410.x
PMCID:
PMC4876864
AbstractArticlePDF–856K
11.
“Receptor protein tyrosine phosphatase alpha enhances rheumatoid synovial fibroblast signaling and promotes arthritis in mice”
Stephanie M. Stanford, Mattias N. D. Svensson, Cristiano Sacchetti, Caila A. Pilo, Dennis J. Wu, William B. Kiosses, Annelie Hellvard, Brith Bergum, German R. Aleman Muench, Christian Elly, Yun-Cai Liu, Jeroen den Hertog, Ari Elson, Jan Sap, Piotr Mydel, David L. Boyle, Maripat Corr, Gary S. Firestein, Nunzio Bottini
Arthritis Rheumatol. Author manuscript; available in PMC 2017 Feb 1.
Published in final edited form as: Arthritis Rheumatol. 2016 Feb; 68(2): 359–369. doi: 10.1002/art.39442
PMCID:
PMC4770259
AbstractArticlePDF–1.7M
12.
STriatal-Enriched protein tyrosine Phosphatase (STEP) Regulates the PTPα/Fyn Signaling Pathway
Jian Xu, Pradeep Kurup, Ethan Foscue, Paul J. Lombroso
J Neurochem. Author manuscript; available in PMC 2016 Aug 1.
Published in final edited form as: J Neurochem. 2015 Aug; 134(4): 629–641. Published online 2015 May 25. doi: 10.1111/jnc.13160
PMCID:
PMC4516628
AbstractArticlePDF–1.2M
13.
Expression of the Immunoglobulin Superfamily Cell Adhesion Molecules in the Developing Spinal Cord and Dorsal Root Ganglion
Zirong Gu, Fumiyasu Imai, In Jung Kim, Hiroko Fujita, Kei ichi Katayama, Kensaku Mori, Yoshihiro Yoshihara, Yutaka Yoshida
PLoS One. 2015; 10(3): e0121550. Published online 2015 Mar 31. doi: 10.1371/journal.pone.0121550
PMCID:
PMC4380438
AbstractArticlePDF–36M
14.
Interactions of the Protein-tyrosine Phosphatase-α with the Focal Adhesion Targeting Domain of Focal Adhesion Kinase Are Involved in Interleukin-1 Signaling in Fibroblasts
Qin Wang, Yongqiang Wang, Dominik Fritz, Dhaarmini Rajshankar, Gregory P. Downey, Christopher A. McCulloch
J Biol Chem. 2014 Jun 27; 289(26): 18427–18441. Published online 2014 May 12. doi: 10.1074/jbc.M113.540294
PMCID:
PMC4140282
AbstractArticlePDF–5.6M
15.
Protein tyrosine phosphatases ε and α perform nonredundant roles in osteoclasts
Eynat Finkelshtein, Sutada Lotinun, Einat Levy-Apter, Esther Arman, Jeroen den Hertog, Roland Baron, Ari Elson
Mol Biol Cell. 2014 Jun 1; 25(11): 1808–1818. doi: 10.1091/mbc.E14-03-0788
PMCID:
PMC4038506
AbstractArticlePDF–1.9M
16.
Protein Tyrosine Phosphatase α Mediates Profibrotic Signaling in Lung Fibroblasts through TGF-β Responsiveness
Yael Aschner, Anthony P. Khalifah, Natalie Briones, Cory Yamashita, Lior Dolgonos, Scott K. Young, Megan N. Campbell, David W.H. Riches, Elizabeth F. Redente, William J. Janssen, Peter M. Henson, Jan Sap, Nathalie Vacaresse, Andras Kapus, Christopher A.G. McCulloch, Rachel L. Zemans, Gregory P. Downey
Am J Pathol. 2014 May; 184(5): 1489–1502. doi: 10.1016/j.ajpath.2014.01.016
PMCID:
PMC4005983
AbstractArticlePDF–2.3M
17.
Grb2 Promotes Integrin-Induced Focal Adhesion Kinase (FAK) Autophosphorylation and Directs the Phosphorylation of Protein Tyrosine Phosphatase α by the Src-FAK Kinase Complex
Suzanne Y. S. Cheng, Guobin Sun, David D. Schlaepfer, Catherine J. Pallen
Mol Cell Biol. 2014 Feb; 34(3): 348–361. doi: 10.1128/MCB.00825-13
PMCID:
PMC3911518
AbstractArticlePDF–2.2M
18.
Protein Tyrosine Phosphatase α in the Dorsomedial Striatum Promotes Excessive Ethanol-Drinking Behaviors
Sami Ben Hamida, Emmanuel Darcq, Jun Wang, Su Wu, Khanhky Phamluong, Viktor Kharazia, Dorit Ron
J Neurosci. 2013 Sep 4; 33(36): 14369–14378. doi: 10.1523/JNEUROSCI.1954-13.2013
Correction in:
J Neurosci. 2015 Dec 9; 35(49): 16295–16296.
PMCID:
PMC3761047
AbstractArticlePDF–2.1M
19.
Abnormal myelination in the spinal cord of PTPα-knockout mice
Quan-Hong Ma, Tao Xiang, Zara Zhuyun Yang, Xu Zhang, Jude Taylor, Zhi-Cheng Xiao
Cell Adh Migr. 2013 Jul 1; 7(4): 370–376. Published online 2013 Jul 17. doi: 10.4161/cam.25652
PMCID:
PMC3739814
AbstractArticlePDF–1.9M
20.
Role of PTPα in the Destruction of Periodontal Connective Tissues
Dhaarmini Rajshankar, Corneliu Sima, Qin Wang, Stephanie R. Goldberg, Mwayi Kazembe, Yongqiang Wang, Michael Glogauer, Gregory P. Downey, Christopher A. McCulloch
PLoS One. 2013; 8(8): e70659. Published online 2013 Aug 5. doi: 10.1371/journal.pone.0070659
PMCID:
PMC3734242
AbstractArticlePDF–11M

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