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Select item 108865911.

Comprehensive Analysis of the Role of Fibrinogen and Thrombin in Clot Formation and Structure for Plasma and Purified Fibrinogen

Rebecca A. Risman, Heather A. Belcher, Ranjini K. Ramanujam, John W. Weisel, Nathan E. Hudson, Valerie Tutwiler

Biomolecules. 2024 Feb; 14(2): 230. Published online 2024 Feb 16. doi: 10.3390/biom14020230

PMCID:: PMC10886591

Abstract Article PDF–3.5M

Select item 105241922.

Impact of fibrinogen, fibrin thrombi and thrombin on cancer cell extravasation using in vitro microvascular networks

Emmanouil Angelidakis, Sophia Chen, Shun Zhang, Zhengpeng Wan, Roger D. Kamm, Sarah E. Shelton

Adv Healthc Mater. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: Adv Healthc Mater. 2023 Jul; 12(19): e2202984. Published online 2023 May 12. doi: 10.1002/adhm.202202984

PMCID:: PMC10524192

Abstract Article PDF–2.0M

Select item 103658843.

Low α-Thrombin/GPIbα Interaction Is a Potential Contributor to Platelet Hyper-reactivity in COVID-19 Patients

Younes Zaid, Loubna Khalki, Farid Jalali, Youssef Tijani, Nabil Zaid, Abdallah Naya, Mounia Oudghiri, Khadija Akarid, Ejaife O. Agbani, Fadila Guessous

Thromb Haemost. 2023 Aug; 123(8): 804–807. Published online 2023 May 2. doi: 10.1055/a-2072-0366

PMCID:: PMC10365884

Article PDF–888K

Select item 102509174.

Thrombogenic potential of picomolar coagulation factor XIa is mediated by thrombin wave propagation

Leonid A. Parunov, Yideng Liang, Qijin Lu, Alexey M. Shibeko, Erik I. Tucker, Timothy K. Lee, Fazoil I. Ataullakhanov, Dorothy E. Scott, Mikhail V. Ovanesov

Blood Adv. 2023 Jun 13; 7(11): 2622–2631. Published online 2023 Feb 3. doi: 10.1182/bloodadvances.2022008743

PMCID:: PMC10250917

Abstract Article PDF–1.2M

Select item 101772395.

Thrombin, a Key Driver of Pathological Inflammation in the Brain

Jaclyn Iannucci, Paula Grammas

Cells. 2023 May; 12(9): 1222. Published online 2023 Apr 23. doi: 10.3390/cells12091222

PMCID:: PMC10177239

Abstract Article PDF–689K

Select item 101453736.

Inflammatory Response and Activation of Coagulation after COVID-19 Infection

Anna Glória Fonseca Teodoro, Wellington Francisco Rodrigues, Thais Soares Farnesi-de-Assunção, Anna V. Bernardes e Borges, Malu Mateus Santos Obata, José Rodrigues do Carmo Neto, Djalma A. Alves da Silva, Leonardo E. Andrade-Silva, Chamberttan S. Desidério, Juliana C. Costa-Madeira, Rafaela M. Barbosa, Andrezza C. C. Hortolani Cunha, Loren Q. Pereira, Fernanda Bernadelli de Vito, Sarah Cristina Sato Vaz Tanaka, Fernanda R. Helmo, Marcela Rezende Lemes, Laís M. Barbosa, Rafael O. Trevisan, Fabiano V. Mundim, Ana Carolina M. Oliveira-Scussel, Paulo Roberto Resende Junior, Ivan B. Monteiro, Yulsef M. Ferreira, Guilherme H. Machado, Kennio Ferreira-Paim, Hélio Moraes-Souza, Carlo José Freire de Oliveira, Virmondes Rodrigues Júnior, Marcos Vinicius da Silva

Viruses. 2023 Apr; 15(4): 938. Published online 2023 Apr 10. doi: 10.3390/v15040938

PMCID:: PMC10145373

Abstract Article PDF–295K

Select item 100915987.

Integrative analysis of HASMCs gene expression profile revealed the role of thrombin in the pathogenesis of atherosclerosis

Yichen Zhang, Lin Sun, Xingsheng Wang, Qingbo Zhou

BMC Cardiovasc Disord. 2023; 23: 191. Published online 2023 Apr 12. doi: 10.1186/s12872-023-03211-0

PMCID:: PMC10091598

Abstract Article PDF–4.8M

Select item 99224688.

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia

Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen

J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0

PMCID:: PMC9922468

Abstract Article PDF–4.9M

Select item 97725589.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 964871010.

Impact of prothrombin and factor V Leiden mutations on the progression of fibrosis in patients with chronic hepatitis C

Mary Naguib, Wael Abdel-Razek, Suzanne Estaphan, Eman Abdelsameea, Mohamed Abdel-Samiee, Nevine F. Shafik

PLoS One. 2022; 17(11): e0276592. Published online 2022 Nov 10. doi: 10.1371/journal.pone.0276592

PMCID:: PMC9648710

Abstract Article PDF–659K

Select item 944065311.

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy

Shouheng Jin, Xing He, Ling Ma, Zhen Zhuang, Yiliang Wang, Meng Lin, Sihui Cai, Lu Wei, Zheyu Wang, Zhiyao Zhao, Yaoxing Wu, Lin Sun, Chunwei Li, Weihong Xie, Yong Zhao, Zhou Songyang, Ke Peng, Jincun Zhao, Jun Cui

Nat Commun. 2022; 13: 5204. Published online 2022 Sep 3. doi: 10.1038/s41467-022-32957-y

PMCID:: PMC9440653

Abstract Article PDF–2.9M

Select item 942709612.

How thrombomodulin enables W215A/E217A thrombin to cleave protein C but not fibrinogen

Riley B. Peacock, Taylor McGrann, Sofia Zaragoza, Elizabeth A. Komives

Biochemistry. Author manuscript; available in PMC 2022 Aug 30.

Published in final edited form as: Biochemistry. 2022 Jan 18; 61(2): 77–84. Published online 2022 Jan 3. doi: 10.1021/acs.biochem.1c00635

PMCID:: PMC9427096

Abstract Article PDF–1.4M

Select item 929308013.

Thrombomodulin in patients with mild to moderate bleeding tendency

Dino Mehic, Alexander Tolios, Stefanie Hofer, Cihan Ay, Helmuth Haslacher, Kate Downes, Matthias Haimel, Ingrid Pabinger, Johanna Gebhart

Haemophilia. 2021 Nov; 27(6): 1028–1036. Published online 2021 Oct 10. doi: 10.1111/hae.14433

PMCID:: PMC9293080

Abstract Article PDF–384K

Select item 912329414.

Role of LL-37 in thrombotic complications in patients with COVID-19

Zilei Duan, Juan Zhang, Xue Chen, Ming Liu, Hongwen Zhao, Lin Jin, Zhiye Zhang, Ning Luan, Ping Meng, Jing Wang, Zhaoxia Tan, Yaxiong Li, Guohong Deng, Ren Lai

Cell Mol Life Sci. 2022 Jun; 79(6): 309. Published online 2022 May 21. doi: 10.1007/s00018-022-04309-y

PMCID:: PMC9123294

Abstract Article PDF–3.6M

Select item 905883615.

The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside

Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang

J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009

PMCID:: PMC9058836

Abstract Article PDF–2.9M

Select item 899044416.

Light Chain Mutation Effects on the Dynamics of Thrombin

Dizhou Wu, Jiajie Xiao, Freddie R. Salsbury, Jr.

J Chem Inf Model. Author manuscript; available in PMC 2022 Apr 8.

Published in final edited form as: J Chem Inf Model. 2021 Feb 22; 61(2): 950–965. Published online 2021 Jan 15. doi: 10.1021/acs.jcim.0c01303

PMCID:: PMC8990444

Abstract Article PDF–4.0M

Select item 894246917.

Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry

Edward R Kastenhuber, Marisa Mercadante, Benjamin Nilsson-Payant, Jared L Johnson, Javier A Jaimes, Frauke Muecksch, Yiska Weisblum, Yaron Bram, Vasuretha Chandar, Gary R Whittaker, Benjamin R tenOever, Robert E Schwartz, Lewis Cantley

eLife. 2022; 11: e77444. Published online 2022 Mar 23. doi: 10.7554/eLife.77444

PMCID:: PMC8942469

Abstract Article PDF–751K

Select item 880874118.

Generation of an anticoagulant aptamer that targets factor V/Va and disrupts the FVa-membrane interaction in normal and COVID-19 patient samples

Erin E. Soule, Haixiang Yu, Lyra Olson, Ibtehaj Naqvi, Shekhar Kumar, Sriram Krishnaswamy, Bruce A. Sullenger

Cell Chem Biol. 2022 Feb 17; 29(2): 215–225.e5. Published online 2022 Feb 2. doi: 10.1016/j.chembiol.2022.01.009

PMCID:: PMC8808741

Abstract Article PDF–2.8M

Select item 851692219.

Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53

Yafei Guo, Qin Li, Gang Zhao, Jie Zhang, Hang Yuan, Tianyu Feng, Deqiong Ou, Rui Gu, Siqi Li, Kai Li, Ping Lin

Cell Death Dis. 2021 Oct; 12(10): 945. Published online 2021 Oct 14. doi: 10.1038/s41419-021-04208-3

PMCID:: PMC8516922

Abstract Article PDF–8.2M

Select item 847106520.

Recognition Interface of the Thrombin Binding Aptamer Requires Antiparallel Topology of the Quadruplex Core

Julia Svetlova, Makar Sardushkin, Natalia Kolganova, Edward Timofeev

Biomolecules. 2021 Sep; 11(9): 1332. Published online 2021 Sep 9. doi: 10.3390/biom11091332

PMCID:: PMC8471065

Abstract Article PDF–2.1M

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