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Items: 1 to 20 of 33

1.
Unveiling the structural mechanisms of nonpeptide ligand recognition and activation in human chemokine receptor CCR8
Shan Jiang, Xi Lin, Lijie Wu, Ling Wang, Yiran Wu, Ziyi Xu, Fei Xu
Sci Adv. 2024 Feb 2; 10(5): eadj7500. Published online 2024 Feb 2. doi: 10.1126/sciadv.adj7500
PMCID:
PMC10836724
AbstractArticlePDF–6.4M
2.
Development of a cellular model to study CCR8 signaling in tumor-infiltrating regulatory T cells
Libao Liu, Laurie Rangan, Nathan Vanalken, Qianqian Kong, Susan Schlenner, Steven De Jonghe, Dominique Schols, Tom Van Loy
Cancer Immunol Immunother. 2024 Jan; 73(1): 11. Published online 2024 Jan 17. doi: 10.1007/s00262-023-03607-z
PMCID:
PMC10794316
AbstractArticlePDF–1.5M
3.
USP2 Inhibits Lung Cancer Pathogenesis by Reducing ARID2 Protein Degradation via Ubiquitination
Lihuan Zhu, Zhizhong Chen, Tianxing Guo, Wenshu Chen, Lilan Zhao, Lingwen Guo, Xiaojie Pan
Biomed Res Int. 2022; 2022: 1525216. Published online 2022 Dec 15. doi: 10.1155/2022/1525216
PMCID:
PMC9779997
AbstractArticlePDF–2.3M
4.
Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibody
Jessica D. Weaver, Edward C. Stack, Joshua A. Buggé, Changyun Hu, Lara McGrath, Amy Mueller, Masie Wong, Boris Klebanov, Tanzila Rahman, Rosemary Kaufman, Christine Fregeau, Vikki Spaulding, Michelle Priess, Kristen Legendre, Sarah Jaffe, Dhruvkumar Upadhyay, Anirudh Singh, Chang-Ai Xu, Kristin Krukenberg, Yan Zhang, Yassine Ezzyat, Dorothée Saddier Axe, Michelle R. Kuhne, Michael A. Meehl, Donald R. Shaffer, Brian M. Weist, Dmitri Wiederschain, Fabien Depis, Monica Gostissa
Oncoimmunology. 2022; 11(1): 2141007. Published online 2022 Nov 4. doi: 10.1080/2162402X.2022.2141007
PMCID:
PMC9639568
AbstractArticlePDF–20M
5.
CCR8-targeted specific depletion of clonally expanded Treg cells in tumor tissues evokes potent tumor immunity with long-lasting memory
Yujiro Kidani, Wataru Nogami, Yoshiaki Yasumizu, Atsunari Kawashima, Atsushi Tanaka, Yudai Sonoda, Yumi Tona, Kunitaka Nashiki, Reimi Matsumoto, Masaki Hagiwara, Motonao Osaki, Keiji Dohi, Takayuki Kanazawa, Azumi Ueyama, Mai Yoshikawa, Tetsuya Yoshida, Mitsunobu Matsumoto, Kanji Hojo, Satomi Shinonome, Hiroshi Yoshida, Michinari Hirata, Miya Haruna, Yamami Nakamura, Daisuke Motooka, Daisuke Okuzaki, Yasuko Sugiyama, Makoto Kinoshita, Tatsusada Okuno, Taigo Kato, Koji Hatano, Motohide Uemura, Ryoichi Imamura, Kazunori Yokoi, Atsushi Tanemura, Yasushi Shintani, Tadashi Kimura, Norio Nonomura, Hisashi Wada, Masaki Mori, Yuichiro Doki, Naganari Ohkura, Shimon Sakaguchi
Proc Natl Acad Sci U S A. 2022 Feb 15; 119(7): e2114282119. Published online 2022 Feb 9. doi: 10.1073/pnas.2114282119
PMCID:
PMC8851483
AbstractArticlePDF–2.5M
6.
Immunomodulation of T Helper Cells by Tumor Microenvironment in Oral Cancer Is Associated With CCR8 Expression and Rapid Membrane Vitamin D Signaling Pathway
Marco Fraga, Milly Yáñez, Macarena Sherman, Faryd Llerena, Mauricio Hernandez, Guillermo Nourdin, Francisco Álvarez, Joaquín Urrizola, César Rivera, Liliana Lamperti, Lorena Nova, Silvia Castro, Omar Zambrano, Alejandro Cifuentes, León Campos, Sergio Moya, Juan Pastor, Marcelo Nuñez, Jorge Gatica, Jorge Figueroa, Felipe Zúñiga, Carlos Salomón, Gustavo Cerda, Ricardo Puentes, Gonzalo Labarca, Mabel Vidal, Reuben McGregor, Estefania Nova-Lamperti
Front Immunol. 2021; 12: 643298. Published online 2021 May 7. doi: 10.3389/fimmu.2021.643298
PMCID:
PMC8137990
AbstractArticlePDF–9.1M
7.
Clinical and prognostic significance of CC chemokine receptor type 8 protein expression in gastrointestinal stromal tumors
Huai-Liang Li, Lin-Hua Wang, Yi-Lin Hu, Ying Feng, Xiao-Hong Li, Yi-Fei Liu, Peng Li, Qin-Sheng Mao, Wan-Jiang Xue
World J Gastroenterol. 2020 Aug 21; 26(31): 4656–4668. Published online 2020 Aug 21. doi: 10.3748/wjg.v26.i31.4656
PMCID:
PMC7445867
AbstractArticlePDF–5.0M
8.
CCL18 enhances migration, invasion and EMT by binding CCR8 in bladder cancer cells
Xiaoqiang Liu, Xiangyun Xu, Wen Deng, Mingchuan Huang, Yanlong Wu, Zhengtao Zhou, Ke Zhu, Yibing Wang, Xinfu Cheng, Xiaochen Zhou, Luyao Chen, Yu Li, Gongxian Wang, Bin Fu
Mol Med Rep. 2019 Mar; 19(3): 1678–1686. Published online 2018 Dec 24. doi: 10.3892/mmr.2018.9791
PMCID:
PMC6390063
AbstractArticlePDF–1.6M
9.
CCR8 Expression Defines Tissue-Resident Memory T Cells in Human Skin
Michelle L. McCully, Kristin Ladell, Robert Andrews, Rhiannon E. Jones, Kelly L. Miners, Laureline Roger, Duncan M. Baird, Mark J. Cameron, Zita M. Jessop, Iain S. Whitaker, Eleri L. Davies, David A. Price, Bernhard Moser
J Immunol. 2018 Mar 1; 200(5): 1639–1650. Published online 2018 Feb 2. doi: 10.4049/jimmunol.1701377
PMCID:
PMC5818732
AbstractArticlePDF–1.7M
10.
CCR8+FOXp3+ Treg cells as master drivers of immune regulation
Yiftah Barsheshet, Gizi Wildbaum, Eran Levy, Alon Vitenshtein, Chika Akinseye, Jeremy Griggs, Sergio A. Lira, Nathan Karin
Proc Natl Acad Sci U S A. 2017 Jun 6; 114(23): 6086–6091. Published online 2017 May 22. doi: 10.1073/pnas.1621280114
PMCID:
PMC5468670
AbstractArticlePDF–1.0M
11.
Systematic protein–protein interaction mapping for clinically relevant human GPCRs
Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar
Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430
PMCID:
PMC5371730
AbstractArticlePDF–4.1M
12.
Role of Conserved Disulfide Bridges and Aromatic Residues in Extracellular Loop 2 of Chemokine Receptor CCR8 for Chemokine and Small Molecule Binding
Line Barington, Pia C. Rummel, Michael Lückmann, Heidi Pihl, Olav Larsen, Viktorija Daugvilaite, Anders H. Johnsen, Thomas M. Frimurer, Stefanie Karlshøj, Mette M. Rosenkilde
J Biol Chem. 2016 Jul 29; 291(31): 16208–16220. Published online 2016 May 19. doi: 10.1074/jbc.M115.706747
PMCID:
PMC4965569
AbstractArticlePDF–1.4M
13.
Positive intratumoral chemokine (C-C motif) receptor 8 expression predicts high recurrence risk of post-operation clear-cell renal cell carcinoma patients
Qiang Fu, Yuan Chang, Lin Zhou, Huimin An, Yu Zhu, Le Xu, Weijuan Zhang, Jiejie Xu
Oncotarget. 2016 Feb 16; 7(7): 8413–8421. Published online 2015 Dec 24. doi: 10.18632/oncotarget.6761
PMCID:
PMC4885002
AbstractArticlePDF–3.2M
14.
Skin Metabolites Define a New Paradigm in the Localization of Skin Tropic Memory T Cells
Michelle L. McCully, Paul J. Collins, Timothy R. Hughes, Christopher P. Thomas, Jaak Billen, Valerie B. O’Donnell, Bernhard Moser
J Immunol. 2015 Jul 1; 195(1): 96–104. Published online 2015 May 22. doi: 10.4049/jimmunol.1402961
PMCID:
PMC4472944
AbstractArticlePDF–1.2M
15.
Expression of the Chemokine Receptor Gene, CCR8, is Associated with DUSP22 Rearrangements in Anaplastic Large Cell Lymphoma
Xiaoming Xing, Thomas J. Flotte, Mark E. Law, Anthony J. Blahnik, Wee-Joo Chng, Gaofeng Huang, Ryan A. Knudson, Rhett P. Ketterling, Julie C. Porcher, Stephen M. Ansell, Jagmohan Sidhu, Ahmet Dogan, Andrew L. Feldman
Appl Immunohistochem Mol Morphol. Author manuscript; available in PMC 2016 Sep 1.
Published in final edited form as: Appl Immunohistochem Mol Morphol. 2015 Sep; 23(8): 580–589. doi: 10.1097/PAI.0000000000000118
PMCID:
PMC4427553
AbstractArticlePDF–1.3M
16.
HIV-2 interaction with cell coreceptors: amino acids within the V1/V2 region of viral envelope are determinant for CCR8, CCR5 and CXCR4 usage
Quirina Santos-Costa, Maria Manuel Lopes, Marta Calado, José Miguel Azevedo-Pereira
Retrovirology. 2014; 11: 99. Published online 2014 Nov 25. doi: 10.1186/s12977-014-0099-3
PMCID:
PMC4251929
AbstractArticlePDF–2.1M
17.
Linkages between HIV-1 specificity for CCR5 or CXCR4 and in vitro usage of alternative coreceptors during progressive HIV-1 subtype C infection
Kieran Cashin, Martin R Jakobsen, Jasminka Sterjovski, Michael Roche, Anne Ellett, Jacqueline K Flynn, Katharina Borm, Maelenn Gouillou, Melissa J Churchill, Paul R Gorry
Retrovirology. 2013; 10: 98. Published online 2013 Sep 16. doi: 10.1186/1742-4690-10-98
PMCID:
PMC3849974
AbstractArticlePDF–1.0M
18.
Epidermis instructs skin homing receptor expression in human T cells
Michelle L. McCully, Kristin Ladell, Svetlana Hakobyan, Robert E. Mansel, David A. Price, Bernhard Moser
Blood. 2012 Nov 29; 120(23): 4591–4598. Prepublished online 2012 Oct 4. doi: 10.1182/blood-2012-05-433037
PMCID:
PMC3790942
AbstractArticle
19.
Identification of human CCR8 as a CCL18 receptor
Sabina A. Islam, Morris F. Ling, John Leung, Wayne G. Shreffler, Andrew D. Luster
J Exp Med. 2013 Sep 23; 210(10): 1889–1898. doi: 10.1084/jem.20130240
PMCID:
PMC3782048
AbstractArticlePDF–1.9M
20.
Expansion of CCR8+ inflammatory myeloid cells in cancer patients with urothelial and renal carcinomas
Evgeniy Eruslanov, Taryn Stoffs, Wan-Ju Kim, Irina Daurkin, Scott M. Gilbert, Li-Ming Su, Johannes Vieweg, Yehia Daaka, Sergei Kusmartsev
Clin Cancer Res. Author manuscript; available in PMC 2014 Apr 1.
Published in final edited form as: Clin Cancer Res. 2013 Apr 1; 19(7): 1670–1680. Published online 2013 Jan 30. doi: 10.1158/1078-0432.CCR-12-2091
PMCID:
PMC3618575
AbstractArticlePDF–2.0M

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