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Select item 112721841.

BRCA1 and 53BP1 Regulate Reprogramming Efficiency by Mediating DNA Repair Pathway Choice at Replication-associated Double-Strand Breaks

Daniela Georgieva, Ning Wang, Angelo Taglialatela, Stepan Jerabek, Colleen R. Reczek, Pei Xin Lim, Julie Sung, Qian Du, Michiko Horiguchi, Maria Jasin, Alberto Ciccia, Richard Baer, Dieter Egli

Cell Rep. Author manuscript; available in PMC 2024 Jul 25.

Published in final edited form as: Cell Rep. 2024 Apr 23; 43(4): 114006. Published online 2024 Mar 30. doi: 10.1016/j.celrep.2024.114006

PMCID:: PMC11272184

Abstract Article PDF–2.7M

Select item 111593852.

Alteration of p53‐binding protein 1 expression during skin carcinogenesis: Association with genomic instability

Yuki Naruke, Masahiro Nakashima, Keiji Suzuki, Mutsumi Matsuu‐Matsuyama, Kazuko Shichijo, Hisayoshi Kondo, Ichiro Sekine

Cancer Sci. 2008 May; 99(5): 946–951. Published online 2008 Apr 1. doi: 10.1111/j.1349-7006.2008.00786.x

PMCID:: PMC11159385

Abstract Article PDF–1.5M

Select item 111481843.

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek

Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x

PMCID:: PMC11148184

Abstract Article PDF–8.1M

Select item 111432184.

Evolved histone tail regulates 53BP1 recruitment at damaged chromatin

Jessica L. Kelliher, Melissa L. Folkerts, Kaiyuan V. Shen, Wan Song, Kyle Tengler, Clara M. Stiefel, Seong-Ok Lee, Eloise Dray, Weixing Zhao, Brian Koss, Nicholas R. Pannunzio, Justin W. Leung

Nat Commun. 2024; 15: 4634. Published online 2024 May 31. doi: 10.1038/s41467-024-49071-w

PMCID:: PMC11143218

Abstract Article PDF–4.8M

Select item 110245175.

The dimeric deubiquitinase USP28 integrates 53BP1 and MYC functions to limit DNA damage

Chao Jin, Elias Einig, Wenshan Xu, Ravi Babu Kollampally, Andreas Schlosser, Michael Flentje, Nikita Popov

Nucleic Acids Res. 2024 Apr 12; 52(6): 3011–3030. Published online 2024 Jan 16. doi: 10.1093/nar/gkae004

PMCID:: PMC11024517

Abstract Article PDF–2.8M

Select item 107633346.

Extracellular vesicle-derived TP53BP1, CD34, and PBX1 from human peripheral blood serve as potential biomarkers for the assessment and prediction of vascular aging

Yichao Wen, Haiyang Chen, Yu Wang, Yiqing Sun, Fangfang Dou, Xiling Du, Te Liu, Chuan Chen

Hereditas. 2024; 161: 3. Published online 2024 Jan 3. doi: 10.1186/s41065-023-00306-8

PMCID:: PMC10763334

Abstract Article PDF–7.1M

Select item 107028217.

PLK1 promotes the mitotic surveillance pathway by controlling cytosolic 53BP1 availability

Matteo Burigotto, Vincenza Vigorito, Colin Gliech, Alessia Mattivi, Sabrina Ghetti, Alessandra Bisio, Graziano Lolli, Andrew J Holland, Luca L Fava

EMBO Rep. 2023 Dec; 24(12): e57234. Published online 2023 Oct 27. doi: 10.15252/embr.202357234

PMCID:: PMC10702821

Abstract Article PDF–3.6M

Select item 104151208.

ATM–ESCO2–SMC3 axis promotes 53BP1 recruitment in response to DNA damage and safeguards genome integrity by stabilizing cohesin complex

Jianfeng Fu, Siru Zhou, Huilin Xu, Liming Liao, Hui Shen, Peng Du, Xiaofeng Zheng

Nucleic Acids Res. 2023 Aug 11; 51(14): 7376–7391. Published online 2023 Jun 28. doi: 10.1093/nar/gkad533

PMCID:: PMC10415120

Abstract Article PDF–2.3M

Select item 102801479.

DNA damage‐induced cellular senescence is regulated by 53BP1 accumulation in the nuclear foci and phase separation

Tsukasa Oda, Nanami Gotoh, Tetsuhiro Kasamatsu, Hiroshi Handa, Takayuki Saitoh, Nobuo Sasaki

Cell Prolif. 2023 Jun; 56(6): e13398. Published online 2023 Jan 15. doi: 10.1111/cpr.13398

PMCID:: PMC10280147

Abstract Article PDF–2.9M

Select item 1023742210.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1011297711.

Incorporation of 53BP1 into phase-separated bodies in cancer cells during aberrant mitosis

Marina Bleiler, Aiyana Cyr, Dennis L. Wright, Charles Giardina

J Cell Sci. 2023 Jan 1; 136(1): jcs260027. Published online 2023 Jan 6. doi: 10.1242/jcs.260027

PMCID:: PMC10112977

Abstract Article

Select item 1006619012.

TRABID overexpression enables synthetic lethality to PARP inhibitor via prolonging 53BP1 retention at double-strand breaks

Jian Ma, Yingke Zhou, Penglin Pan, Haixin Yu, Zixi Wang, Lei Lily Li, Bing Wang, Yuqian Yan, Yunqian Pan, Qi Ye, Tianjie Liu, Xiaoyu Feng, Shan Xu, Ke Wang, Xinyang Wang, Yanlin Jian, Bohan Ma, Yizeng Fan, Yang Gao, Haojie Huang, Lei Li

Nat Commun. 2023; 14: 1810. Published online 2023 Mar 31. doi: 10.1038/s41467-023-37499-5

PMCID:: PMC10066190

Abstract Article PDF–5.6M

Select item 1001836013.

HDGFRP3 interaction with 53BP1 promotes DNA double-strand break repair

Zhen Zhang, William E Samsa, Yanyan De, Fan Zhang, Ofer Reizes, Alexandru Almasan, Zihua Gong

Nucleic Acids Res. 2023 Mar 21; 51(5): 2238–2256. Published online 2023 Feb 16. doi: 10.1093/nar/gkad073

Correction in:: Nucleic Acids Res. 2024 Mar 21; 52(5): 2759–2760.

PMCID:: PMC10018360

Abstract Article PDF–1.8M

Select item 976969814.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 974423915.

TRIM44 mediated p62 deubiquitination enhances DNA damage repair by increasing nuclear FLNA and 53BP1 expression

Lin Lyu, Tsung-Chin Lin, Nami McCarty

Oncogene. Author manuscript; available in PMC 2022 Dec 12.

Published in final edited form as: Oncogene. 2021 Aug; 40(32): 5116–5130. Published online 2021 Jul 1. doi: 10.1038/s41388-021-01890-7

PMCID:: PMC9744239

Abstract Article PDF–4.4M

Select item 973405816.

Identification of a novel GR-ARID1a-P53BP1 protein complex involved in DNA damage repair and cell cycle regulation

Felicity E. Stubbs, Benjamin P. Flynn, Caroline A. Rivers, Matthew T. Birnie, Andrew Herman, Erin E. Swinstead, Songjoon Baek, Hai Fang, Jillian Temple, Jason S. Carroll, Gordon L. Hager, Stafford L. Lightman, Becky L. Conway-Campbell

Oncogene. 2022; 41(50): 5347–5360. Published online 2022 Nov 7. doi: 10.1038/s41388-022-02516-2

PMCID:: PMC9734058

Abstract Article PDF–3.5M

Select item 970808617.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676

PMCID:: PMC9708086

Abstract Article PDF–8.5M

Select item 939206318.

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling

Yansheng Zhai, Xiaoyan Huang, Keren Zhang, Yuchen Huang, Yanlong Jiang, Jingwei Cui, Zhe Zhang, Cookson K. C. Chiu, Weiye Zhong, Gang Li

Nat Commun. 2022; 13: 4906. Published online 2022 Aug 20. doi: 10.1038/s41467-022-32689-z

PMCID:: PMC9392063

Abstract Article PDF–2.0M

Select item 927928519.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 911973620.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

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