PMC Links for GEO Profiles (Select 93729723) - PMC

Héctor David Graterol Sequera, Josué Lacerda de Souza, José do Espírito Santo Junior, Lener Santos da Silva, Suzana Kanawati Pinheiro, Herllon Karllos Athaydes Kerr, Mara Lúcia Gomes de Souza, Marcus Vinitius de Farias Guerra, Tirza Gabrielle Ramos de Mesquita, Rajendranath Ramasawmy

PLoS Negl Trop Dis. 2023 Jun; 17(6): e0011416. Published online 2023 Jun 5. doi: 10.1371/journal.pntd.0011416

PMCID:: PMC10270566

Abstract Article PDF–860K

Select item 100422165.

Protein folding stress potentiates NLRP1 and CARD8 inflammasome activation

Elizabeth L. Orth-He, Hsin-Che Huang, Sahana D. Rao, Qinghui Wang, Qifeng Chen, Claire M. O’Mara, Ashley J. Chui, Michelle Saoi, Andrew R. Griswold, Abir Bhattacharjee, Daniel P. Ball, Justin R. Cross, Daniel A. Bachovchin

Cell Rep. Author manuscript; available in PMC 2023 Mar 27.

Published in final edited form as: Cell Rep. 2023 Jan 31; 42(1): 111965. Published online 2023 Jan 16. doi: 10.1016/j.celrep.2022.111965

PMCID:: PMC10042216

Abstract Article PDF–2.9M

Select item 99796966.

Inflammasome genes polymorphisms are associated with progression to mechanical ventilation and death in a cohort of hospitalized COVID-19 patients in a reference hospital in Rio de Janeiro, Brazil

Milena Neira-Goulart, Nathalia Beatriz Ramos de Sá, Marcelo Ribeiro-Alves, Hugo Perazzo, Kim Mattos Geraldo, Maria Pia Diniz Ribeiro, Sandra Wagner Cardoso, Beatriz Grinsztejn, Valdiléa G. Veloso, Larissa Rodrigues Gomes, Andressa da Silva Cazote, Dalziza Victalina de Almeida, Carmem Beatriz Wagner Giacoia-Gripp, Fernanda Heloise Côrtes, Mariza Gonçalves Morgado

Gene. 2023 May 20; 865: 147325. Published online 2023 Mar 2. doi: 10.1016/j.gene.2023.147325

PMCID:: PMC9979696

Abstract Article PDF–588K

Select item 99634017.

Association between NLRP3 rs10754558 and CARD8 rs2043211 Variants and Susceptibility to Chronic Kidney Disease

Antonella La Russa, Danilo Lofaro, Alberto Montesanto, Daniele La Russa, Gianluigi Zaza, Simona Granata, Michele Di Dio, Raffaele Serra, Michele Andreucci, Renzo Bonofiglio, Anna Perri

Int J Mol Sci. 2023 Feb; 24(4): 4184. Published online 2023 Feb 20. doi: 10.3390/ijms24044184

PMCID:: PMC9963401

Abstract Article PDF–533K

Select item 99421398.

The NLRP1 and CARD8 inflammasomes detect reductive stress

Qinghui Wang, Jeffrey C. Hsiao, Noah Yardeny, Hsin-Che Huang, Claire M. O’Mara, Elizabeth L. Orth-He, Daniel P. Ball, Ze Zhang, Daniel A. Bachovchin

Cell Rep. Author manuscript; available in PMC 2023 Feb 21.

Published in final edited form as: Cell Rep. 2023 Jan 31; 42(1): 111966. Published online 2023 Jan 16. doi: 10.1016/j.celrep.2022.111966

PMCID:: PMC9942139

Abstract Article PDF–3.4M

Select item 95116809.

Association of CARD8 Activating Polymorphism With Bone Erosion in Cholesteatoma Patients

Neel Sangal, John Yan, Jessica Pryor, Marcus L. Elias, Biju Joseph, Luis Ulloa, Robert W. Jyung

Laryngoscope. Author manuscript; available in PMC 2022 Sep 26.

Published in final edited form as: Laryngoscope. 2021 Feb; 131(2): E605–E611. Published online 2020 May 12. doi: 10.1002/lary.28741

PMCID:: PMC9511680

Abstract Article PDF–417K

Select item 933831310.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Abstract Article PDF–2.8M

Select item 921324711.

A ubiquitin-independent proteasome pathway controls activation of the CARD8 inflammasome

Jeffrey C. Hsiao, Atara R. Neugroschl, Ashley J. Chui, Cornelius Y. Taabazuing, Andrew R. Griswold, Qinghui Wang, Hsin-Che Huang, Elizabeth L. Orth-He, Daniel P. Ball, Giorgos Hiotis, Daniel A. Bachovchin

J Biol Chem. 2022 Jul; 298(7): 102032. Published online 2022 May 14. doi: 10.1016/j.jbc.2022.102032

PMCID:: PMC9213247

Abstract Article PDF–1.7M

Select item 857675212.

Associations of NLRP3 and CARD8 Gene Polymorphisms with Alcohol Dependence and Commonly Related Psychiatric Disorders: a Preliminary Study

Anja Plemenitaš Ilješ, Blanka Kores Plesničar, Vita Dolžan

Arh Hig Rada Toksikol. 2021 Sep; 72(3): 191–197. Published online 2021 Sep 28. doi: 10.2478/aiht-2021-72-3432

PMCID:: PMC8576752

Abstract Article PDF–283K

Select item 842335813.

Dipeptidyl Peptidase 9 Sets a Threshold for CARD8 Inflammasome Formation by Sequestering Its Active C-terminal Fragment

Humayun Sharif, L. Robert Hollingsworth, Andrew R. Griswold, Jeffrey C. Hsiao, Qinghui Wang, Daniel A. Bachovchin, Hao Wu

Immunity. Author manuscript; available in PMC 2022 Jul 13.

Published in final edited form as: Immunity. 2021 Jul 13; 54(7): 1392–1404.e10. Published online 2021 May 20. doi: 10.1016/j.immuni.2021.04.024

PMCID:: PMC8423358

Abstract Article PDF–3.0M

Select item 816503014.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 802949615.

CARD8 is an inflammasome sensor for HIV-1 protease activity

Qiankun Wang, Hongbo Gao, Kolin M. Clark, Christian Shema Mugisha, Keanu Davis, Jack P. Tang, Gray H. Harlan, Carl J. DeSelm, Rachel M. Presti, Sebla B. Kutluay, Liang Shan

Science. Author manuscript; available in PMC 2021 May 19.

Published in final edited form as: Science. 2021 Mar 19; 371(6535): eabe1707. Published online 2021 Feb 4. doi: 10.1126/science.abe1707

PMCID:: PMC8029496

Abstract Article PDF–2.2M

Select item 791919916.

Genetic variation in CARD8, a gene coding for an NLRP3 inflammasome-associated protein, alters the genetic risk for diabetic nephropathy in the context of type 2 diabetes mellitus

Fotis Tsetsos, Athanasios Roumeliotis, Xanthippi Tsekmekidou, Sophia Alexouda, Stefanos Roumeliotis, Marios Theodoridis, Elias Thodis, Stylianos Panagoutsos, Nikolaos Papanas, Dimitrios Papazoglou, Kalliopi Kotsa, John G Yovos, Efstratios Maltezos, Ploumis Passadakis, Peristera Paschou, Marianthi Georgitsi

Diab Vasc Dis Res. 2020 Nov-Dec; 17(6): 1479164120970892. Published online 2020 Nov 8. doi: 10.1177/1479164120970892

PMCID:: PMC7919199

Abstract Article PDF–483K

Select item 779438617.

Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes

L. Robert Hollingsworth, Liron David, Yang Li, Andrew R. Griswold, Jianbin Ruan, Humayun Sharif, Pietro Fontana, Elizabeth L. Orth-He, Tian-Min Fu, Daniel A. Bachovchin, Hao Wu

Nat Commun. 2021; 12: 189. Published online 2021 Jan 8. doi: 10.1038/s41467-020-20320-y

PMCID:: PMC7794386

Abstract Article PDF–4.1M

Select item 779436218.

Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8

Qin Gong, Kim Robinson, Chenrui Xu, Phuong Thao Huynh, Kelvin Han Chung Chong, Eddie Yong Jun Tan, Jiawen Zhang, Zhao Zhi Boo, Daniel Eng Thiam Teo, Kenneth Lay, Yaming Zhang, John Soon Yew Lim, Wah Ing Goh, Graham Wright, Franklin L. Zhong, Bruno Reversade, Bin Wu

Nat Commun. 2021; 12: 188. Published online 2021 Jan 8. doi: 10.1038/s41467-020-20319-5

PMCID:: PMC7794362

Abstract Article PDF–5.3M

Select item 764468319.

Expression of CARD8 in human atherosclerosis and its regulation of inflammatory proteins in human endothelial cells

Geena V. Paramel, Glykeria Karadimou, Anna Göthlin Eremo, Liza U. Ljungberg, Ulf Hedin, Peder S. Olofsson, Lasse Folkersen, Gabrielle Paulsson-Berne, Allan Sirsjö, Karin Fransén

Sci Rep. 2020; 10: 19108. Published online 2020 Nov 5. doi: 10.1038/s41598-020-73600-4

Correction in:: Sci Rep. 2021; 11: 8852.

PMCID:: PMC7644683

Abstract Article PDF–3.9M

Select item 759459520.

Activation of the CARD8 Inflammasome Requires a Disordered Region

Ashley J. Chui, Andrew R. Griswold, Cornelius Y. Taabazuing, Elizabeth L. Orth, Kuo Gai, Sahana D. Rao, Daniel P. Ball, Jeffrey C. Hsiao, Daniel A. Bachovchin

Cell Rep. Author manuscript; available in PMC 2020 Oct 29.

Published in final edited form as: Cell Rep. 2020 Oct 13; 33(2): 108264. doi: 10.1016/j.celrep.2020.108264

PMCID:: PMC7594595

Abstract Article PDF–1.4M

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