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Select item 110064701.

Single cell RNA-seq identifies a FOS/JUN-related monocyte signature associated with clinical response of heart failure patients with mesenchymal stem cell therapy

Hui Yuan, Pengfei Zhang, Yuanfeng Xin, Zhongmin Liu, Bingren Gao

Aging (Albany NY) 2024 Mar 31; 16(6): 5651–5675. Published online 2024 Mar 20. doi: 10.18632/aging.205670

PMCID:: PMC11006470

Abstract Article PDF–9.7M

Select item 107399862.

Expression of PVRL4, a molecular target for cancer treatment, is transcriptionally regulated by FOS

Tomoyuki Nanamiya, Kiyoko Takane, Kiyoshi Yamaguchi, Yuya Okawara, Mariko Arakawa, Akari Saku, Tsuneo Ikenoue, Tomoko Fujiyuki, Misako Yoneda, Chieko Kai, Yoichi Furukawa

Oncol Rep. 2024 Jan; 51(1): 17. Published online 2023 Dec 5. doi: 10.3892/or.2023.8676

PMCID:: PMC10739986

Abstract Article PDF–3.0M

Select item 106414653.

Molecular profiling of clinical remission in psoriatic arthritis reveals dysregulation of FOS and CCDC50 genes: a gene expression study

Maria Maddalena Angioni, Alberto Floris, Ignazio Cangemi, Mattia Congia, Elisabetta Chessa, Micaela Rita Naitza, Matteo Piga, Alberto Cauli

Front Immunol. 2023; 14: 1274539. Published online 2023 Oct 27. doi: 10.3389/fimmu.2023.1274539

PMCID:: PMC10641465

Abstract Article PDF–1.5M

Select item 106176734.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 104263955.

c‐FOS is an integral component of the IKZF1 transactivator complex and mediates lenalidomide resistance in multiple myeloma

Naoki Osada, Jiro Kikuchi, Hidekatsu Iha, Hiroshi Yasui, Sho Ikeda, Naoto Takahashi, Yusuke Furukawa

Clin Transl Med. 2023 Aug; 13(8): e1364. Published online 2023 Aug 15. doi: 10.1002/ctm2.1364

PMCID:: PMC10426395

Abstract Article PDF–6.0M

Select item 104234826.

Metabolic rewiring controlled by c-Fos governs cartilage integrity in osteoarthritis

Kazuhiko Matsuoka, Latifa Bakiri, Martin Bilban, Stefan Toegel, Arvand Haschemi, Hao Yuan, Maria Kasper, Reinhard Windhager, Erwin F Wagner

Ann Rheum Dis. 2023 Sep; 82(9): 1227–1239. Published online 2023 Jun 21. doi: 10.1136/ard-2023-224002

PMCID:: PMC10423482

Abstract Article PDF–19M

Select item 104114647.

Protection of c-Fos from autophagic degradation by PRMT1-mediated methylation fosters gastric tumorigenesis

Eunji Kim, Laily Rahmawati, Nur Aziz, Han Gyung Kim, Ji Hye Kim, Kyung-Hee Kim, Byong Chul Yoo, Narayana Parameswaran, Jong-Sun Kang, Hoon Hur, Balachandran Manavalan, Jongsung Lee, Jae Youl Cho

Int J Biol Sci. 2023; 19(12): 3640–3660. Published online 2023 Jul 15. doi: 10.7150/ijbs.85126

PMCID:: PMC10411464

Abstract Article PDF–8.4M

Select item 103126748.

AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor

Philipp Trepte, Christopher Secker, Simona Kostova, Sibusiso B. Maseko, Soon Gang Choi, Jeremy Blavier, Igor Minia, Eduardo Silva Ramos, Patricia Cassonnet, Sabrina Golusik, Martina Zenkner, Stephanie Beetz, Mara J. Liebich, Nadine Scharek, Anja Schütz, Marcel Sperling, Michael Lisurek, Yang Wang, Kerstin Spirohn, Tong Hao, Michael A. Calderwood, David E. Hill, Markus Landthaler, Julien Olivet, Jean-Claude Twizere, Marc Vidal, Erich E. Wanker

Version 1. bioRxiv. Preprint. 2023 Jun 14. doi: 10.1101/2023.06.14.544560

Published in:: Mol Syst Biol. 2024 Apr; 20(4): 428–457.

PMCID:: PMC10312674

Abstract Article PDF–9.6M

Select item 102900699.

Loss of function of GATA3 regulates FRA1 and c-FOS to activate EMT and promote mammary tumorigenesis and metastasis

Xiong Liu, Feng Bai, Yuchan Wang, Chuying Wang, Ho Lam Chan, Chenglong Zheng, Jian Fang, Wei-Guo Zhu, Xin-Hai Pei

Cell Death Dis. 2023 Jun; 14(6): 370. Published online 2023 Jun 23. doi: 10.1038/s41419-023-05888-9

PMCID:: PMC10290069

Abstract Article PDF–7.0M

Select item 992693410.

A germline SNP in BRMS1 predisposes patients with lung adenocarcinoma to metastasis and can be ameliorated by targeting c-fos

Yuan Liu, Neel Chudgar, Brooke Mastrogiacomo, Di He, Manendra B. Lankadasari, Samhita Bapat, Gregory D. Jones, Francisco Sanchez-Vega, Kay See Tan, Nikolaus Schultz, Semanti Mukherjee, Kenneth Offit, Yongde Bao, Matthew J. Bott, Natasha Rekhtman, Prasad S. Adusumilli, Bob T. Li, Marty W. Mayo, David R. Jones

Sci Transl Med. Author manuscript; available in PMC 2023 Feb 14.

Published in final edited form as: Sci Transl Med. 2022 Oct 5; 14(665): eabo1050. Published online 2022 Oct 5. doi: 10.1126/scitranslmed.abo1050

PMCID:: PMC9926934

Abstract Article PDF–1.3M

Select item 960039911.

The C-Terminus of the PSMA3 Proteasome Subunit Preferentially Traps Intrinsically Disordered Proteins for Degradation

Assaf Biran, Nadav Myers, Shirel Steinberger, Julia Adler, Marianna Riutin, Karin Broennimann, Nina Reuven, Yosef Shaul

Cells. 2022 Oct; 11(20): 3231. Published online 2022 Oct 14. doi: 10.3390/cells11203231

PMCID:: PMC9600399

Abstract Article PDF–4.1M

Select item 946392112.

c-FOS Expression Analysis in Pterygia Cell Spot Arrays

STYLIANOS MASTRONIKOLIS, EVANGELOS TSIAMBAS, MARINA PAGKALOU, OLGA Ε. MAKRI, VASILIKI K. THOMOPOULOU, DIMITRIOS PESCHOS, VASILEIOS RAGOS, DIMITRIOS ROUKAS, CONSTANTINOS D. GEORGAKOPOULOS

In Vivo. 2022 Sep-Oct; 36(5): 2143–2148. Published online 2022 Sep 3. doi: 10.21873/invivo.12940

PMCID:: PMC9463921

Abstract Article PDF–503K

Select item 935706013.

Combinatorial Treatment with Poly(ADP-ribose) Polymerase-1 Inhibitors and Cisplatin Attenuates Cervical Cancer Growth Through Fos-Driven Changes in Gene Expression

Rebecca Gupte, Ken Y. Lin, Tulip Nandu, Jayanthi S. Lea, W. Lee Kraus

Mol Cancer Res. Author manuscript; available in PMC 2023 Feb 5.

Published in final edited form as: Mol Cancer Res. 2022 Aug 5; 20(8): 1183–1192. doi: 10.1158/1541-7786.MCR-22-0111

PMCID:: PMC9357060

Abstract Article PDF–2.1M

Select item 931879514.

An interplay between the p38 MAPK pathway and AUBPs regulates c-fos mRNA stability during mitogenic stimulation

Maria Sol Degese, Tamara Tanos, Julian Naipauer, Tim Gingerich, Diego Chiappe, Pablo Echeverria, Jonathan LaMarre, J. Silvio Gutkind, Omar A. Coso

Biochem J. Author manuscript; available in PMC 2022 Jul 26.

Published in final edited form as: Biochem J. 2015 Apr 1; 467(1): 77–90. doi: 10.1042/BJ20141100

PMCID:: PMC9318795

Abstract Article PDF–4.3M

Select item 913496315.

LncRNA CRART16/miR-122-5p/FOS axis promotes angiogenesis of gastric cancer by upregulating VEGFD expression

Junling Zhang, Xiaocong Pang, Lili Lei, Jixin Zhang, Xiaoqian Zhang, Ziyi Chen, Jing Zhu, Yong Jiang, Guowei Chen, Yingchao Wu, Tao Wu, Yisheng Pan, Yucun Liu, Yimin Cui, Xin Wang

Aging (Albany NY) 2022 May 15; 14(9): 4137–4157. Published online 2022 May 10. doi: 10.18632/aging.204078