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Select item 105658761.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 101516152.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 95884983.

A novel superfamily of bridge-like lipid transfer proteins

Sarah D. Neuman, Tim P. Levine, Arash Bashirullah

Trends Cell Biol. Author manuscript; available in PMC 2023 Nov 1.

Published in final edited form as: Trends Cell Biol. 2022 Nov; 32(11): 962–974. Published online 2022 Apr 28. doi: 10.1016/j.tcb.2022.03.011

PMCID:: PMC9588498

Abstract Article PDF–1.3M

Select item 87576164.

Vps13-like proteins provide phosphatidylethanolamine for GPI anchor synthesis in the ER

Alexandre Toulmay, Fawn B. Whittle, Jerry Yang, Xiaofei Bai, Jessica Diarra, Subhrajit Banerjee, Tim P. Levine, Andy Golden, William A. Prinz

J Cell Biol. 2022 Mar 7; 221(3): e202111095. Published online 2022 Jan 11. doi: 10.1083/jcb.202111095

PMCID:: PMC8757616

Abstract Article PDF–4.9M

Select item 83641815.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76641207.

Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane

Molly M. Hannigan, Alyson M. Hoffman, J. Will Thompson, Tianli Zheng, Christopher V. Nicchitta

Mol Cell Proteomics. 2020 Nov; 19(11): 1826–1849. Published online 2020 Aug 10. doi: 10.1074/mcp.RA120.002228

PMCID:: PMC7664120

Abstract Article PDF–4.8M

Select item 75237068.

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis

Katrin Tiemann, Carolina Garri, Sang Bok Lee, Paymaneh D. Malihi, Mincheol Park, Ruth M. Alvarez, Li Peng Yap, Parag Mallick, Jonathan E. Katz, Mitchell E. Gross, Kian Kani

Oncogene. Author manuscript; available in PMC 2020 Sep 29.

Published in final edited form as: Oncogene. 2019 Apr; 38(16): 3003–3018. Published online 2018 Dec 21. doi: 10.1038/s41388-018-0638-9

PMCID:: PMC7523706

Abstract Article PDF–2.3M

Select item 73184009.

KIAA1109 gene mutation in surviving patients with Alkuraya-Kučinskas syndrome: a review of literature

Kishore Kumar, Anikha Bellad, Pramada Prasad, Satish Chandra Girimaji, Babylakshmi Muthusamy

BMC Med Genet. 2020; 21: 136. Published online 2020 Jun 26. doi: 10.1186/s12881-020-01074-2

PMCID:: PMC7318400

Abstract Article PDF–1.7M

Select item 680016410.

Systematic identification of host cell regulators of Legionella pneumophila pathogenesis using a genome-wide CRISPR screen

Edwin E. Jeng, Varun Bhadkamkar, Nnejiuwa U. Ibe, Haley Gause, Lihua Jiang, Joanne Chan, Ruiqi Jian, David Jimenez-Morales, Erica Stevenson, Nevan J. Krogan, Danielle L. Swaney, Michael P. Snyder, Shaeri Mukherjee, Michael C. Bassik

Cell Host Microbe. Author manuscript; available in PMC 2020 Oct 9.

Published in final edited form as: Cell Host Microbe. 2019 Oct 9; 26(4): 551–563.e6. Published online 2019 Sep 17. doi: 10.1016/j.chom.2019.08.017

PMCID:: PMC6800164

Abstract Article PDF–2.8M

Select item 641165711.

Endosomal trafficking defects in patient cells with KIAA1109 biallelic variants

Megan S. Kane, Callie J. Diamonstein, Natalie Hauser, John F. Deeken, John E. Niederhuber, Thierry Vilboux

Genes Dis. 2019 Mar; 6(1): 56–67. Published online 2019 Jan 7. doi: 10.1016/j.gendis.2018.12.004

PMCID:: PMC6411657

Abstract Article PDF–2.4M

Select item 638658812.

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2

Joanna R. Kovalski, Aparna Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Yonglu Che, Glenn G. Wozniak, Paul A. Khavari

Mol Cell. Author manuscript; available in PMC 2020 Feb 21.

Published in final edited form as: Mol Cell. 2019 Feb 21; 73(4): 830–844.e12. Published online 2019 Jan 10. doi: 10.1016/j.molcel.2018.12.001

PMCID:: PMC6386588

Abstract Article PDF–1.7M

Select item 631496613.

Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study

Nick Shrine, Michael A Portelli, Catherine John, María Soler Artigas, Neil Bennett, Robert Hall, Jon Lewis, Amanda P Henry, Charlotte K Billington, Azaz Ahmad, Richard J Packer, Dominick Shaw, Zara E K Pogson, Andrew Fogarty, Tricia M McKeever, Amisha Singapuri, Liam G Heaney, Adel H Mansur, Rekha Chaudhuri, Neil C Thomson, John W Holloway, Gabrielle A Lockett, Peter H Howarth, Ratko Djukanovic, Jenny Hankinson, Robert Niven, Angela Simpson, Kian Fan Chung, Peter J Sterk, John D Blakey, Ian M Adcock, Sile Hu, Yike Guo, Maen Obeidat, Don D Sin, Maarten van den Berge, David C Nickle, Yohan Bossé, Martin D Tobin, Ian P Hall, Christopher E Brightling, Louise V Wain, Ian Sayers

Lancet Respir Med. 2019 Jan; 7(1): 20–34. doi: 10.1016/S2213-2600(18)30389-8

PMCID:: PMC6314966

Abstract Article

Select item 616668214.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 582692615.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 577744916.

KIAA1109 Variants Are Associated with a Severe Disorder of Brain Development and Arthrogryposis

Lucie Gueneau, Richard J. Fish, Hanan E. Shamseldin, Norine Voisin, Frédéric Tran Mau-Them, Egle Preiksaitiene, Glen R. Monroe, Angeline Lai, Audrey Putoux, Fabienne Allias, Qamariya Ambusaidi, Laima Ambrozaityte, Loreta Cimbalistienė, Julien Delafontaine, Nicolas Guex, Mais Hashem, Wesam Kurdi, Saumya Shekhar Jamuar, Lim J. Ying, Carine Bonnard, Tommaso Pippucci, Sylvain Pradervand, Bernd Roechert, Peter M. van Hasselt, Michaël Wiederkehr, Caroline F. Wright, DDD Study, Ioannis Xenarios, Gijs van Haaften, Charles Shaw-Smith, Erica M. Schindewolf, Marguerite Neerman-Arbez, Damien Sanlaville, Gaëtan Lesca, Laurent Guibaud, Bruno Reversade, Jamel Chelly, Vaidutis Kučinskas, Fowzan S. Alkuraya, Alexandre Reymond

Am J Hum Genet. 2018 Jan 4; 102(1): 116–132. Published online 2017 Dec 28. doi: 10.1016/j.ajhg.2017.12.002

PMCID:: PMC5777449

Abstract Article PDF–2.3M

Select item 549522517.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 509804118.

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions

Charles A. S. Banks, Gina Boanca, Zachary T. Lee, Cassandra G. Eubanks, Gaye L. Hattem, Allison Peak, Lauren E. Weems, Juliana J. Conkright, Laurence Florens, Michael P. Washburn

Mol Cell Proteomics. 2016 Nov; 15(11): 3435–3449. Published online 2016 Sep 8. doi: 10.1074/mcp.M116.060509

PMCID:: PMC5098041

Abstract Article PDF–2.1M

Select item 492242019.

Meta-analysis of genome-wide association studies identifies 10 loci influencing allergic sensitization

Klaus Bønnelykke, Melanie C Matheson, Tune H Pers, Raquel Granell, David P Strachan, Alexessander Couto Alves, Allan Linneberg, John A Curtin, Nicole M Warrington, Marie Standl, Marjan Kerkhof, Ingileif Jonsdottir, Blazenka K Bukvic, Marika Kaakinen, Patrick Sleimann, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Katharina Schramm, Svetlana Baltic, Eskil Kreiner-Møller, Angela Simpson, Beate St Pourcain, Lachlan Coin, Jennie Hui, Eugene H Walters, Carla M T Tiesler, David L Duffy, Graham Jones, AAGC, Susan M Ring, Wendy L McArdle, Loren Price, Colin F Robertson, Juha Pekkanen, Clara S Tang, Elisabeth Thiering, Grant W Montgomery, Anna-Liisa Hartikainen, Shyamali C Dharmage, Lise L Husemoen, Christian Herder, John P Kemp, Paul Elliot, Alan James, Melanie Waldenberger, Michael J Abramson, Benjamin P Fairfax, Julian C Knight, Ramneek Gupta, Philip J Thompson, Patrick Holt, Peter Sly, Joel N Hirschhorn, Mario Blekic, Stephan Weidinger, Hakon Hakonarsson, Kari Stefansson, Joachim Heinrich, Dirkje S Postma, Adnan Custovic, Craig E Pennell, Marjo-Riitta Jarvelin, Gerard H Koppelman, Nicholas Timpson, Manuel A Ferreira, Hans Bisgaard, A John Henderson

Nat Genet. Author manuscript; available in PMC 2016 Jun 27.

Published in final edited form as: Nat Genet. 2013 Aug; 45(8): 902–906. Published online 2013 Jun 30. doi: 10.1038/ng.2694

PMCID:: PMC4922420

Abstract Article PDF–937K

Select item 481716420.

Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131

Radhika A. Varier, Enrique Carrillo de Santa Pau, Petra van der Groep, Rik G. H. Lindeboom, Filomena Matarese, Anneloes Mensinga, Arne H. Smits, Raghu Ram Edupuganti, Marijke P. Baltissen, Pascal W. T. C. Jansen, Natalie ter Hoeve, Danny R. van Weely, Ina Poser, Paul J. van Diest, Hendrik G. Stunnenberg, Michiel Vermeulen

J Biol Chem. 2016 Apr 1; 291(14): 7313–7324. Published online 2016 Feb 3. doi: 10.1074/jbc.M115.701227

PMCID:: PMC4817164

Abstract Article PDF–3.5M

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