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Select item 112656231.

Intrinsically Disordered Membrane Anchors of Rheb, RhoA, and DiRas3 Small GTPases: Molecular Dynamics, Membrane Organization, and Interactions

Chase M. Hutchins, Alemayehu A. Gorfe

J Phys Chem B. Author manuscript; available in PMC 2024 Jul 23.

Published in final edited form as: J Phys Chem B. 2024 Jul 11; 128(27): 6518–6528. Published online 2024 Jun 28. doi: 10.1021/acs.jpcb.4c01876

PMCID:: PMC11265623

Abstract Article PDF–2.2M

Select item 112148912.

Genetic disruption of ATAT1 causes RhoA downregulation through abnormal truncation of C/EBPβ

Jee-Hye Choi, Jangho Jeong, Jaegu Kim, Eunae You, Seula Keum, Seongeun Song, Ye Eun Hwang, Minjoo Ji, Kwon-Sik Park, Sangmyung Rhee

BMB Rep. 2024 Jun 30; 57(6): 293–298. Published online 2024 May 3. doi: 10.5483/BMBRep.2023-0230

PMCID:: PMC11214891

Abstract Article PDF–3.7M

Select item 111600563.

Overexpression of RhoA enhances peritoneal dissemination: RhoA suppression with Lovastatin may be useful for ovarian cancer

Akiko Horiuchi, Norihiko Kikuchi, Ryosuke Osada, Cuiju Wang, Akiko Hayashi, Toshio Nikaido, Ikuo Konishi

Cancer Sci. 2008 Dec; 99(12): 2532–2539. Published online 2008 Nov 24. doi: 10.1111/j.1349-7006.2008.00977.x

PMCID:: PMC11160056

Abstract Article PDF–325K

Select item 111155024.

Celiac disease IgA modulates vascular permeability in vitro through the activity of transglutaminase 2 and RhoA

Essi Myrsky, Sergio Caja, Zsofi Simon-Vecsei, Ilma R. Korponay-Szabo, Cristina Nadalutti, Russell Collighan, Alexandre Mongeot, Martin Griffin, Markku Mäki, Katri Kaukinen, Katri Lindfors

Cell Mol Life Sci. 2009 Oct; 66(20): 3375–3385. Published online 2009 Aug 13. doi: 10.1007/s00018-009-0116-1

PMCID:: PMC11115502

Abstract Article PDF–473K

Select item 111057515.

Transcriptional and post-transcriptional regulation of the genes encoding the small GTPases RhoA, RhoB, and RhoC: implications for the pathogenesis of human diseases

Eirini Nomikou, Melina Livitsanou, Christos Stournaras, Dimitris Kardassis

Cell Mol Life Sci. 2018 Jun; 75(12): 2111–2124. Published online 2018 Mar 2. doi: 10.1007/s00018-018-2787-y

PMCID:: PMC11105751

Abstract Article PDF–1.4M

Select item 109971276.

Hydrostatic pressure mediates epithelial-mesenchymal transition of cholangiocytes through RhoA/ROCK and TGF-β/smad pathways

Mahmoud Osman Khalifa, Chen Yan, Yong Chai, Kosei Ito, Shou-Hua Zhang, Tao-Sheng Li

PLoS One. 2024; 19(4): e0300548. Published online 2024 Apr 5. doi: 10.1371/journal.pone.0300548

PMCID:: PMC10997127

Abstract Article PDF–1.7M

Select item 108670587.

LAMB3 Promotes Myofibrogenesis and Cytoskeletal Reorganization in Endometrial Stromal Cells via the RhoA/ROCK1/MYL9 Pathway

Xiaomei Qin, Bin Zeng, Suren R. Sooranna, Mujun Li

Cell Biochem Biophys. 2024; 82(1): 127–137. Published online 2023 Oct 6. doi: 10.1007/s12013-023-01186-5

PMCID:: PMC10867058

Abstract Article PDF–2.1M

Select item 108216018.

The Snail signaling branch downstream of the TGF-β/Smad3 pathway mediates Rho activation and subsequent stress fiber formation

Mitsuyoshi Motizuki, Takashi Yokoyama, Masao Saitoh, Keiji Miyazawa

J Biol Chem. 2024 Jan; 300(1): 105580. Published online 2023 Dec 21. doi: 10.1016/j.jbc.2023.105580

PMCID:: PMC10821601

Abstract Article PDF–5.5M

Select item 108132239.

Lipopolysaccharide Stimulates A549 Cell Migration through p-Tyr 42 RhoA and Phospholipase D1 Activity

Shohel Mahmud, Amir Hamza, Yoon-Beom Lee, Jung-Ki Min, Rokibul Islam, Oyungerel Dogsom, Jae-Bong Park

Biomolecules. 2024 Jan; 14(1): 6. Published online 2023 Dec 20. doi: 10.3390/biom14010006

PMCID:: PMC10813223

Abstract Article PDF–3.1M

Select item 1058999910.

Mechanism of RhoA regulating benign prostatic hyperplasia: RhoA-ROCK-β-catenin signaling axis and static & dynamic dual roles

Shidong Shan, Min Su, Yan Li, Zhen Wang, Daoquan Liu, Yongying Zhou, Xun Fu, Shu Yang, Junchao Zhang, Jizhang Qiu, Huan Liu, Guang Zeng, Ping Chen, Xinghuan Wang, Michael E. DiSanto, Yuming Guo, Xinhua Zhang

Mol Med. 2023; 29: 139. Published online 2023 Oct 20. doi: 10.1186/s10020-023-00734-2

PMCID:: PMC10589999

Abstract Article PDF–11M

Select item 1048053511.

Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex

Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté

J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123

PMCID:: PMC10480535

Abstract Article PDF–2.4M

Select item 1039887512.

High extracellular glucose promotes cell motility by modulating cell deformability and contractility via the cAMP-RhoA-ROCK axis in human breast cancer cells

Mijung Oh, Skylar Batty, Nayan Banerjee, Tae-Hyung Kim

Mol Biol Cell. 2023 Jul 1; 34(8): ar79. Published online 2023 Jul 1. doi: 10.1091/mbc.E22-12-0560

PMCID:: PMC10398875

Abstract Article PDF–7.7M

Select item 1029012413.

Structure of human TRPV4 in complex with GTPase RhoA

Kirill D. Nadezhdin, Irina A. Talyzina, Aravind Parthasarathy, Arthur Neuberger, David X. Zhang, Alexander I. Sobolevsky

Nat Commun. 2023; 14: 3733. Published online 2023 Jun 23. doi: 10.1038/s41467-023-39346-z

PMCID:: PMC10290124

Abstract Article PDF–4.4M

Select item 1029008114.

TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease

Do Hoon Kwon, Feng Zhang, Brett A. McCray, Shasha Feng, Meha Kumar, Jeremy M. Sullivan, Wonpil Im, Charlotte J. Sumner, Seok-Yong Lee

Nat Commun. 2023; 14: 3732. Published online 2023 Jun 23. doi: 10.1038/s41467-023-39345-0

PMCID:: PMC10290081

Abstract Article PDF–6.1M

Select item 1028411715.

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry

Fenglong Jiao, Leah J. Salituro, Clinton Yu, Craig B. Gutierrez, Scott D. Rychnovsky, Lan Huang

Anal Chem. Author manuscript; available in PMC 2023 Jun 21.

Published in final edited form as: Anal Chem. 2023 Jan 31; 95(4): 2532–2539. Published online 2023 Jan 18. doi: 10.1021/acs.analchem.2c04986

PMCID:: PMC10284117

Abstract Article PDF–2.5M

Select item 1026278116.

RHOA, a small G-protein, signals to mitophagy through regulation of PINK1 protein stability and protects cardiomyocytes against ischemia

Michelle Tu, Shigeki Miyamoto

Autophagy. 2023; 19(6): 1865–1866. Published online 2022 Oct 18. doi: 10.1080/15548627.2022.2132707

PMCID:: PMC10262781

Abstract Article PDF–265K

Select item 1023742217.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1011914518.

Septin11 promotes hepatocellular carcinoma cell motility by activating RhoA to regulate cytoskeleton and cell adhesion

Lisheng Fu, Xiaoyan Wang, Ying Yang, MeiHua Chen, Adilijiang Kuerban, Haojie Liu, Yiwei Dong, QianQian Cai, Mingzhe Ma, XingZhong Wu

Cell Death Dis. 2023 Apr; 14(4): 280. Published online 2023 Apr 20. doi: 10.1038/s41419-023-05726-y

PMCID:: PMC10119145

Abstract Article PDF–16M

Select item 1009264319.

BAG6 supports stress fiber formation by preventing the ubiquitin-mediated degradation of RhoA

Maho Miyauchi, Reina Matsumura, Hiroyuki Kawahara

Mol Biol Cell. 2023 Apr 1; 34(4): ar34. Published online 2023 Mar 17. doi: 10.1091/mbc.E22-08-0355

PMCID:: PMC10092643

Abstract Article PDF–23M

Select item 995018320.

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment

Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini

Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3