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Items: 1 to 20 of 95

1.
Increased NOX1 and DUOX2 expression in the colonic mucosa of patients with chronic functional constipation
Xiuqin Wei, Mei Xue, Chunbo Kang, Lei Gao, Mengqiao Zhang, Chao Ma, Wei Jia, Yufeng Zheng, Lei Cao, Pan Chen, Shujing Jiang, Fong-Fong Chu, Qiang Gao
Medicine (Baltimore) 2022 Aug 12; 101(32): e30028. Published online 2022 Aug 12. doi: 10.1097/MD.0000000000030028
PMCID:
PMC9371511
AbstractArticlePDF–1.2M
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
Nuclear factor-kappaB regulates the transcription of NADPH oxidase 1 in human alveolar epithelial cells
Weijing Wu, Li Li, Xiaoshan Su, Zhixing Zhu, Xiaoping Lin, Jiamin Zhang, Zesen Zhuang, Hongyi Cai, Wenjie Huang
BMC Pulm Med. 2021; 21: 98. Published online 2021 Mar 23. doi: 10.1186/s12890-021-01464-z
PMCID:
PMC7988993
AbstractArticlePDF–2.0M
4.
NOX1 inhibition attenuates the development of a pro‐tumorigenic environment in experimental hepatocellular carcinoma
Astrid Vandierendonck, Helena Degroote, Bart Vanderborght, Xavier Verhelst, Anja Geerts, Lindsey Devisscher, Hans Van Vlierberghe
J Exp Clin Cancer Res. 2021; 40: 40. Published online 2021 Jan 23. doi: 10.1186/s13046-021-01837-6
PMCID:
PMC7824948
AbstractArticlePDF–2.4M
5.
Serum Level of Xanthine Oxidase, Uric Acid, and NADPH Oxidase 1 in Stage I of Multiple Myeloma
Maryam Kohsari, Mohammad Hassan Khadem Ansari, Yousef Rasmi
Asian Pac J Cancer Prev. 2020 Aug; 21(8): 2237–2242. doi: 10.31557/APJCP.2020.21.8.2237
PMCID:
PMC7771943
AbstractArticlePDF–402K
6.
In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators
Jennifer L. Franks, Raquel C. Martinez-Chacin, Xianxi Wang, Rochelle L. Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L. Bolhuis, Taylor P. Enrico, Ryan D. Mouery, Jeffrey S. Damrauer, Feng Yan, Joseph S. Harrison, M. Ben Major, Katherine A. Hoadley, Aussie Suzuki, Scott B. Rothbart, Nicholas G. Brown, Michael J. Emanuele
PLoS Biol. 2020 Dec; 18(12): e3000975. Published online 2020 Dec 11. doi: 10.1371/journal.pbio.3000975
PMCID:
PMC7758050
AbstractArticlePDF–4.2M
7.
ABCG1 Attenuates Oxidative Stress Induced by H2O2 through the Inhibition of NADPH Oxidase and the Upregulation of Nrf2-Mediated Antioxidant Defense in Endothelial Cells
Jiahong Xue, Jiali Fan, Yuan Li, Wenhuan Wu, Qing Yan, Qiangsun Zheng
Anal Cell Pathol (Amst) 2020; 2020: 2095645. Published online 2020 Dec 3. doi: 10.1155/2020/2095645
PMCID:
PMC7732382
AbstractArticlePDF–1.6M
8.
NADPH oxidase 1 is highly expressed in human large and small bowel cancers
Jiamo Lu, Guojian Jiang, Yongzhong Wu, Smitha Antony, Jennifer L. Meitzler, Agnes Juhasz, Han Liu, Krishnendu Roy, Hala Makhlouf, Rodrigo Chuaqui, Donna Butcher, Mariam M. Konaté, James H. Doroshow
PLoS One. 2020; 15(5): e0233208. Published online 2020 May 19. doi: 10.1371/journal.pone.0233208
PMCID:
PMC7237001
AbstractArticlePDF–3.2M
9.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
10.
Nox1/Ref-1-mediated activation of CREB promotes Gremlin1-driven endothelial cell proliferation and migration
Daniel S. de Jesus, Evan DeVallance, Yao Li, Micol Falabella, Danielle Guimaraes, Sruti Shiva, Brett A. Kaufman, Mark T. Gladwin, Patrick J. Pagano
Redox Biol. 2019 Apr; 22: 101138. Published online 2019 Feb 8. doi: 10.1016/j.redox.2019.101138
PMCID:
PMC6395885
AbstractArticlePDF–2.5M
11.
The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2
Joanna R. Kovalski, Aparna Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Yonglu Che, Glenn G. Wozniak, Paul A. Khavari
Mol Cell. Author manuscript; available in PMC 2020 Feb 21.
Published in final edited form as: Mol Cell. 2019 Feb 21; 73(4): 830–844.e12. Published online 2019 Jan 10. doi: 10.1016/j.molcel.2018.12.001
PMCID:
PMC6386588
AbstractArticlePDF–1.7M
12.
Subverted regulation of Nox1 NADPH oxidase-dependent oxidant generation by protein disulfide isomerase A1 in colon carcinoma cells with overactivated KRas
Tiphany Coralie De Bessa, Alessandra Pagano, Ana Iochabel Soares Moretti, Percillia Victoria Santos Oliveira, Samir Andrade Mendonça, Herve Kovacic, Francisco Rafael Martins Laurindo
Cell Death Dis. 2019 Feb; 10(2): 143. Published online 2019 Feb 13. doi: 10.1038/s41419-019-1402-y
PMCID:
PMC6374413
AbstractArticlePDF–2.3M
13.
Redox Activation of Nox1 Involves an Intermolecular Disulfide Bond between Protein Disulfide Isomerase and p47phox in Vascular Smooth Muscle Cells
Marcela Gimenez, Sidney Veríssimo-Filho, Ilka Wittig, Brandon M. Schickling, Fabian Hahner, Christoph Schürmann, Luis E.S. Netto, José César Rosa, Ralf P. Brandes, Simone Sartoretto, Lívia De Lucca Camargo, Fernando Abdulkader, Francis J. Miller, Jr., Lucia Rossetti Lopes
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2020 Feb 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2019 Feb; 39(2): 224–236. doi: 10.1161/ATVBAHA.118.311038
PMCID:
PMC6344286
AbstractArticlePDF–950K
14.
Increased oxidative stress mediates the antitumor effect of PARP inhibition in ovarian cancer
Dong Hou, Zhaojian Liu, Xiuhua Xu, Qiao Liu, Xiyu Zhang, Beihua Kong, Jian-Jun Wei, Yaoqin Gong, Changshun Shao
Redox Biol. 2018 Jul; 17: 99–111. Published online 2018 Mar 30. doi: 10.1016/j.redox.2018.03.016
PMCID:
PMC6006521
AbstractArticlePDF–3.9M
15.
NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease
T. Schwerd, R. V. Bryant, S. Pandey, M. Capitani, L. Meran, J.-B. Cazier, J. Jung, K. Mondal, M. Parkes, CG Mathew, K. Fiedler, D. J. McCarthy, WGS500 Consortium, Oxford IBD cohort study investigators, COLORS in IBD, UK IBD Genetics Consortium, PB Sullivan, A. Rodrigues, SPL Travis, C. Moore, J. Sambrook, W. H. Ouwehand, D. J. Roberts, J. Danesh, INTERVAL Study, R. K. Russell, D. C. Wilson, J. R. Kelsen, R. Cornall, L. A. Denson, S. Kugathasan, U. G. Knaus, E. Goncalves Serra, C. A. Anderson, R. H. Duerr, D. P. B. McGovern, J. Cho, F. Powrie, V. S. W. Li, A. M. Muise, H. H. Uhlig
Mucosal Immunol. Author manuscript; available in PMC 2018 May 1.
Published in final edited form as: Mucosal Immunol. 2018 Mar; 11(2): 562–574. Published online 2017 Nov 1. doi: 10.1038/mi.2017.74
PMCID:
PMC5924597
AbstractArticlePDF–1.9M
16.
SUMO1/UBC9-decreased Nox1 activity inhibits reactive oxygen species generation and apoptosis in diabetic retinopathy
Jiaoli Hu, Pengcheng Xue, Xinbang Mao, Lin Xie, Guodong Li, Zhipeng You
Mol Med Rep. 2018 Jan; 17(1): 1690–1698. Published online 2017 Nov 13. doi: 10.3892/mmr.2017.8037
PMCID:
PMC5780112
AbstractArticlePDF–1.9M
17.
Endothelial Nox1 oxidase assembly in human pulmonary arterial hypertension; driver of Gremlin1-mediated proliferation
Imad Al Ghouleh, Sanghamitra Sahoo, Daniel N. Meijles, Jefferson H. Amaral, Daniel S. de Jesus, John Sembrat, Mauricio Rojas, Dmitry A. Goncharov, Elena A. Goncharova, Patrick J. Pagano
Clin Sci (Lond) Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Clin Sci (Lond). 2017 Aug 1; 131(15): 2019–2035. Published online 2017 Jul 16. doi: 10.1042/CS20160812
PMCID:
PMC5705051
AbstractArticlePDF–2.1M
18.
The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1
Daniel N. Meijles, Sanghamitra Sahoo, Imad Al Ghouleh, Jefferson H. Amaral, Raquel Bienes-Martinez, Heather E. Knupp, Shireen Attaran, John C. Sembrat, Seyed M. Nouraie, Mauricio M. Rojas, Enrico M. Novelli, Mark T. Gladwin, Jeffrey S. Isenberg, Eugenia Cifuentes-Pagano, Patrick J. Pagano
Sci Signal. Author manuscript; available in PMC 2018 Apr 17.
Published in final edited form as: Sci Signal. 2017 Oct 17; 10(501): eaaj1784. Published online 2017 Oct 17. doi: 10.1126/scisignal.aaj1784
PMCID:
PMC5679204
AbstractArticlePDF–2.1M
19.
Antioxidants and NOX1/NOX4 inhibition blocks TGFβ1-induced CCN2 and α-SMA expression in dermal and gingival fibroblasts
Hannah Murphy-Marshman, Katherine Quensel, Xu Shi-wen, Rebecca Barnfield, Jacalyn Kelly, Alex Peidl, Richard J. Stratton, Andrew Leask
PLoS One. 2017; 12(10): e0186740. Published online 2017 Oct 19. doi: 10.1371/journal.pone.0186740
PMCID:
PMC5648211
AbstractArticlePDF–4.1M
20.
A Novel Interaction of PAK4 with PPAR? to Regulate Nox1 and Radiation-Induced Epithelial-to-Mesenchymal Transition in Glioma
Divya Kesanakurti, Dilip Maddirela, Sanjeeva Mohanam, Balveen Kaur, Vinay K. Puduvalli
Oncogene. Author manuscript; available in PMC 2017 Nov 22.
Published in final edited form as: Oncogene. 2017 Sep 14; 36(37): 5309–5320. Published online 2017 May 22. doi: 10.1038/onc.2016.261
PMCID:
PMC5599308
AbstractArticlePDF–2.5M

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