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Items: 1 to 20 of 38

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
The CUL5 E3 ligase complex negatively regulates central signaling pathways in CD8+ T cells
Xiaofeng Liao, Wenxue Li, Hongyue Zhou, Barani Kumar Rajendran, Ao Li, Jingjing Ren, Yi Luan, David A. Calderwood, Benjamin Turk, Wenwen Tang, Yansheng Liu, Dianqing Wu
Nat Commun. 2024; 15: 603. Published online 2024 Jan 19. doi: 10.1038/s41467-024-44885-0
PMCID:
PMC10798966
AbstractArticlePDF–3.5M
3.
Cullin5 drives experimental asthma exacerbations by modulating alveolar macrophage antiviral immunity
Haibo Zhang, Keke Xue, Wen Li, Xinyi Yang, Yusen Gou, Xiao Su, Feng Qian, Lei Sun
Nat Commun. 2024; 15: 252. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44168-0
PMCID:
PMC10766641
AbstractArticlePDF–6.5M
4.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
5.
The AAA‐ATPase ATAD1 and its partners promote degradation of desmin intermediate filaments in muscle
Dina Aweida, Shenhav Cohen
EMBO Rep. 2022 Dec; 23(12): e55175. Published online 2022 Oct 24. doi: 10.15252/embr.202255175
PMCID:
PMC9724657
AbstractArticlePDF–3.0M
6.
The ubiquitin ligase Cul5 regulates CD4+ T cell fate choice and allergic inflammation
Binod Kumar, Natania S. Field, Dale D. Kim, Asif A. Dar, Yanqun Chen, Aishwarya Suresh, Christopher F. Pastore, Li-Yin Hung, Nadia Porter, Keisuke Sawada, Palak Shah, Omar Elbulok, Emily K. Moser, De’Broski R. Herbert, Paula M. Oliver
Nat Commun. 2022; 13: 2786. Published online 2022 May 19. doi: 10.1038/s41467-022-30437-x
PMCID:
PMC9120070
AbstractArticlePDF–2.4M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
CRL5-dependent regulation of the small GTPases ARL4C and ARF6 controls hippocampal morphogenesis
Jisoo S. Han, Keiko Hino, Wenzhe Li, Raenier V. Reyes, Cesar P. Canales, Adam M. Miltner, Yasmin Haddadi, Junqing Sun, Chao-Yin Chen, Anna La Torre, Sergi Simó
Proc Natl Acad Sci U S A. 2020 Sep 15; 117(37): 23073–23084. Published online 2020 Sep 1. doi: 10.1073/pnas.2002749117
PMCID:
PMC7502717
AbstractArticlePDF–3.3M
9.
Comparative Analysis of cul5 and rbx2 Expression in the Developing and Adult Murine Brain and Their Essentiality During Mouse Embryogenesis
Keiko Hino, Sergi Simó, Jonathan A. Cooper
Dev Dyn. Author manuscript; available in PMC 2019 Nov 7.
Published in final edited form as: Dev Dyn. 2018 Nov; 247(11): 1227–1236. Published online 2018 Nov 7. doi: 10.1002/dvdy.24675
PMCID:
PMC6639038
AbstractArticlePDF–3.0M
10.
Cullin5 deficiency promotes small-cell lung cancer metastasis by stabilizing integrin β1
Gaoxiang Zhao, Liyan Gong, Dan Su, Yujuan Jin, Chenchen Guo, Meiting Yue, Shun Yao, Zhen Qin, Yi Ye, Ying Tang, Qibiao Wu, Jian Zhang, Binghai Cui, Qiurong Ding, Hsinyi Huang, Liang Hu, Yuting Chen, Peiyuan Zhang, Guohong Hu, Luonan Chen, Kwok-Kin Wong, Daming Gao, Hongbin Ji
J Clin Invest. 2019 Mar 1; 129(3): 972–987. Published online 2019 Jan 28. doi: 10.1172/JCI122779
PMCID:
PMC6391098
AbstractArticlePDF–20M
11.
A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies
David K. Breslow, Sascha Hoogendoorn, Adam R. Kopp, David W. Morgens, Brandon K. Vu, Margaret C. Kennedy, Kyuho Han, Amy Li, Gaelen T. Hess, Michael C. Bassik, James K. Chen, Maxence V. Nachury
Nat Genet. Author manuscript; available in PMC 2018 Aug 19.
Published in final edited form as: Nat Genet. 2018 Mar; 50(3): 460–471. Published online 2018 Feb 19. doi: 10.1038/s41588-018-0054-7
PMCID:
PMC5862771
AbstractArticlePDF–2.5M
12.
RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion
Corinne L. Fairchild, Keiko Hino, Jisoo S. Han, Adam M. Miltner, Gabriel Peinado Allina, Caileigh E. Brown, Marie E. Burns, Anna La Torre, Sergi Simó
Development. 2018 Feb 1; 145(3): dev155283. doi: 10.1242/dev.155283
PMCID:
PMC5817999
AbstractArticle
13.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
14.
Impaired Reelin-Dab1 signaling contributes to neuronal migration deficits of Tuberous Sclerosis Complex
Uk Yeol Moon, Jun Young Park, Raehee Park, Jennifer Y. Cho, Lucinda J. Hughes, James McKenna, III, Laura Goetzl, Seo-Hee Cho, Peter B. Crino, Michael J. Gambello, Seonhee Kim
Cell Rep. Author manuscript; available in PMC 2016 Aug 11.
Published in final edited form as: Cell Rep. 2015 Aug 11; 12(6): 965–978. Published online 2015 Jul 30. doi: 10.1016/j.celrep.2015.07.013
PMCID:
PMC4536164
AbstractArticlePDF–2.4M
15.
Cullin 5 destabilizes Cas to inhibit Src-dependent cell transformation
Anjali Teckchandani, George S. Laszlo, Sergi Simó, Khyati Shah, Carissa Pilling, Alexander A. Strait, Jonathan A. Cooper
J Cell Sci. 2014 Feb 1; 127(3): 509–520. doi: 10.1242/jcs.127829
PMCID:
PMC4007763
AbstractArticle
16.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
17.
Rbx2 regulates neuronal migration through different Cullin5-RING ligase adaptors
Sergi Simó, Jonathan A. Cooper
Dev Cell. Author manuscript; available in PMC 2014 Nov 25.
Published in final edited form as: Dev Cell. 2013 Nov 25; 27(4): 10.1016/j.devcel.2013.09.022. Published online 2013 Nov 7. doi: 10.1016/j.devcel.2013.09.022
PMCID:
PMC3851519
AbstractArticlePDF–6.4M
18.
Suppressor of Cytokine Signaling (SOCS) 5 Utilises Distinct Domains for Regulation of JAK1 and Interaction with the Adaptor Protein Shc-1
Edmond M. Linossi, Indu R. Chandrashekaran, Tatiana B. Kolesnik, James M. Murphy, Andrew I. Webb, Tracy A. Willson, Lukasz Kedzierski, Alex N. Bullock, Jeffrey J. Babon, Raymond S. Norton, Nicos A. Nicola, Sandra E. Nicholson
PLoS One. 2013; 8(8): e70536. Published online 2013 Aug 21. doi: 10.1371/journal.pone.0070536
PMCID:
PMC3749136
AbstractArticlePDF–3.3M
19.
The SOCS Box Domain of SOCS3: Structure and Interaction with the ElonginBC-Cullin5 Ubiquitin Ligase
Jeffrey J. Babon, Jennifer K. Sabo, Alfreda Soetopo, Shenggen Yao, Michael F. Bailey, Jian-Guo Zhang, Nicos A. Nicola, Raymond S. Norton
J Mol Biol. Author manuscript; available in PMC 2013 May 13.
Published in final edited form as: J Mol Biol. 2008 Sep 12; 381(4): 928–940. Published online 2008 Jun 20. doi: 10.1016/j.jmb.2008.06.038
PMCID:
PMC3652878
AbstractArticlePDF–4.6M
20.
RAB-Like 2 Has an Essential Role in Male Fertility, Sperm Intra-Flagellar Transport, and Tail Assembly
Jennifer C. Y. Lo, Duangporn Jamsai, Anne E. O'Connor, Claire Borg, Brett J. Clark, James C. Whisstock, Mark C. Field, Vicki Adams, Tomomoto Ishikawa, R. John Aitken, Belinda Whittle, Christopher C. Goodnow, Christopher J. Ormandy, Moira K. O'Bryan
PLoS Genet. 2012 Oct; 8(10): e1002969. Published online 2012 Oct 4. doi: 10.1371/journal.pgen.1002969
PMCID:
PMC3464206
AbstractArticlePDF–1.8M

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