PMC Links for GEO Profiles (Select 96864687) - PMC

Akinori Endo, Toshiaki Fukushima, Chikage Takahashi, Hikaru Tsuchiya, Fumiaki Ohtake, Sayaka Ono, Tony Ly, Yukiko Yoshida, Keiji Tanaka, Yasushi Saeki, Masayuki Komada

J Cell Biol. 2024 Mar 4; 223(3): e202306013. Published online 2024 Jan 5. doi: 10.1083/jcb.202306013

PMCID:: PMC10783432

Abstract Article PDF–6.4M

Select item 103180704.

piRNA-1742 promotes renal cell carcinoma malignancy by regulating USP8 stability through binding to hnRNPU and thereby inhibiting MUC12 ubiquitination

Wentao Zhang, Zongtai Zheng, Keyi Wang, Weipu Mao, Xue Li, Guangchun Wang, Yuanyuan Zhang, Jianhua Huang, Ning Zhang, Pengfei Wu, Ji Liu, Haimin Zhang, Jianping Che, Bo Peng, Junhua Zheng, Wei Li, Xudong Yao

Exp Mol Med. 2023 Jun; 55(6): 1258–1271. Published online 2023 Jun 19. doi: 10.1038/s12276-023-01010-3

PMCID:: PMC10318070

Abstract Article PDF–8.1M

Select item 102374225.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101858246.

Inhibition of the intracellular domain of Notch1 results in vascular endothelial cell dysfunction in sepsis

Tingyan Liu, Caiyan Zhang, Jiayun Ying, Yaodong Wang, Gangfeng Yan, Yufeng Zhou, Guoping Lu

Front Immunol. 2023; 14: 1134556. Published online 2023 May 2. doi: 10.3389/fimmu.2023.1134556

PMCID:: PMC10185824

Abstract Article PDF–27M

Select item 101366457.

USP8 Down-Regulation Promotes Parkin-Independent Mitophagy in the Drosophila Brain and in Human Neurons

Sofia Mauri, Greta Bernardo, Aitor Martinez, Mariavittoria Favaro, Marta Trevisan, Gael Cobraiville, Marianne Fillet, Federico Caicci, Alexander J. Whitworth, Elena Ziviani

Cells. 2023 Apr; 12(8): 1143. Published online 2023 Apr 13. doi: 10.3390/cells12081143

PMCID:: PMC10136645

Abstract Article PDF–4.7M

Select item 100665628.

Reciprocal regulatory balance within the CLEC16A–RNF41 mitophagy complex depends on an intrinsically disordered protein region

Morgan A. Gingerich, Jie Zhu, Biaoxin Chai, Michael P. Vincent, Nuli Xie, Vaibhav Sidarala, Nicholas A. Kotov, Debashish Sahu, Daniel J. Klionsky, Santiago Schnell, Scott A. Soleimanpour

J Biol Chem. 2023 Apr; 299(4): 103057. Published online 2023 Feb 22. doi: 10.1016/j.jbc.2023.103057

PMCID:: PMC10066562

Abstract Article PDF–1.8M

Select item 99504329.

Targeting ubiquitin-specific protease 8 sensitizes anti-programmed death-ligand 1 immunotherapy of pancreatic cancer

Hanshen Yang, Xiaozhen Zhang, Mengyi Lao, Kang Sun, Lihong He, Jian Xu, Yi Duan, Yan Chen, Honggang Ying, Muchun Li, Chengxiang Guo, Qingsong Lu, Sicheng Wang, Wei Su, Tingbo Liang, Xueli Bai

Cell Death Differ. 2023 Feb; 30(2): 560–575. Published online 2022 Dec 20. doi: 10.1038/s41418-022-01102-z

PMCID:: PMC9950432

Abstract Article PDF–13M

Select item 948193310.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 947374511.

Identification and validation of Selective Deubiquitinase Inhibitors

Anthony C. Varca, Dominick Casalena, Wai Cheung Chan, Bin Hu, Robert S. Magin, Rebekka M. Roberts, Xiaoxi Liu, He Zhu, Hyuk-Soo Seo, Sirano Dhe-Paganon, Jarrod A. Marto, Douglas Auld, Sara J. Buhrlage

Cell Chem Biol. Author manuscript; available in PMC 2022 Dec 16.

Published in final edited form as: Cell Chem Biol. 2021 Dec 16; 28(12): 1758–1771.e13. Published online 2021 Jun 14. doi: 10.1016/j.chembiol.2021.05.012

PMCID:: PMC9473745

Abstract Article PDF–2.3M

Select item 937955312.

USP8 promotes cancer progression and extracellular vesicle‐mediated CD8+ T cell exhaustion by deubiquitinating the TGF‐β receptor TβRII

Feng Xie, Xiaoxue Zhou, Heyu Li, Peng Su, Sijia Liu, Ran Li, Jing Zou, Xiang Wei, Chen Pan, Zhengkui Zhang, Min Zheng, Zhuang Liu, Xuli Meng, Huib Ovaa, Peter ten Dijke, Fangfang Zhou, Long Zhang

EMBO J. 2022 Aug; 41(16): e108791. Published online 2022 Jul 11. doi: 10.15252/embj.2021108791

PMCID:: PMC9379553

Abstract Article PDF–5.6M

Select item 934857613.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 933831314.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Abstract Article PDF–2.8M

Select item 927928515.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 917141116.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 916475817.

Molecular mechanism of lncRNA SNHG12 in immune escape of non-small cell lung cancer through the HuR/PD-L1/USP8 axis

Yusheng Huang, Lei Xia, Xiangwu Tan, Jingyi Zhang, Weiwei Zeng, Benxu Tan, Xian Yu, Wei Fang, Zhenzhou Yang

Cell Mol Biol Lett. 2022; 27: 43. Published online 2022 Jun 3. doi: 10.1186/s11658-022-00343-7

PMCID:: PMC9164758

Abstract Article PDF–6.9M

Select item 911973618.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 910630319.

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors

Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen

Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638

PMCID:: PMC9106303

Abstract Article PDF–918K

Select item 897143120.

Usp8 promotes tumor cell migration through activating the JNK pathway

Yunhe Zhao, Dezhen Peng, Yanyun Liu, Qian Zhang, Bin Liu, Yanran Deng, Wenhao Ding, Zizhang Zhou, Qingxin Liu

Cell Death Dis. 2022 Mar; 13(3): 286. Published online 2022 Mar 31. doi: 10.1038/s41419-022-04749-1

PMCID:: PMC8971431

Abstract Article PDF–5.8M

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