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Items: 1 to 20 of 64

1.
JAK-STAT signaling maintains homeostasis in T cells and macrophages
Nikolaus Fortelny, Matthias Farlik, Victoria Fife, Anna-Dorothea Gorki, Caroline Lassnig, Barbara Maurer, Katrin Meissl, Marlies Dolezal, Laura Boccuni, Aarathy Ravi Sundar Jose Geetha, Mojoyinola Joanna Akagha, Anzhelika Karjalainen, Stephen Shoebridge, Asma Farhat, Ulrike Mann, Rohit Jain, Shweta Tikoo, Nina Zila, Wolfgang Esser-Skala, Thomas Krausgruber, Katarzyna Sitnik, Thomas Penz, Anastasiya Hladik, Tobias Suske, Sophie Zahalka, Martin Senekowitsch, Daniele Barreca, Florian Halbritter, Sabine Macho-Maschler, Wolfgang Weninger, Heidi A. Neubauer, Richard Moriggl, Sylvia Knapp, Veronika Sexl, Birgit Strobl, Thomas Decker, Mathias Müller, Christoph Bock
Nat Immunol. 2024; 25(5): 847–859. Published online 2024 Apr 24. doi: 10.1038/s41590-024-01804-1
PMCID:
PMC11065702
AbstractArticlePDF–10M
2.
Long non-coding RNA TTTY15 sponges miR-520a-3p to exacerbate neural apoptosis induced by cerebral ischemia/reperfusion via targeting IRF9 both in vivo and in vitro
Huan Wang, Hui Yang, Mingxiu Chang, Feifei Sun, Huiping Qi, Xuling Li
Biomed J. 2023 Apr; 46(2): 100530. Published online 2022 Apr 16. doi: 10.1016/j.bj.2022.04.001
PMCID:
PMC10267968
AbstractArticlePDF–2.4M
3.
An MRTF-A–ZEB1–IRF9 axis contributes to fibroblast–myofibroblast transition and renal fibrosis
Qianwen Zhao, Tinghui Shao, Yuwen Zhu, Gengjie Zong, Junjie Zhang, Shifan Tang, Yanshan Lin, Hongzhen Ma, Zhifan Jiang, Yong Xu, Xiaoyan Wu, Tao Zhang
Exp Mol Med. 2023 May; 55(5): 987–998. Published online 2023 May 1. doi: 10.1038/s12276-023-00990-6
PMCID:
PMC10238398
AbstractArticlePDF–5.5M
4.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
5.
Osteoclast fusion and bone loss are restricted by interferon inducible guanylate binding proteins
David E. Place, R. K. Subbarao Malireddi, Jieun Kim, Peter Vogel, Masahiro Yamamoto, Thirumala-Devi Kanneganti
Nat Commun. 2021; 12: 496. Published online 2021 Jan 21. doi: 10.1038/s41467-020-20807-8
PMCID:
PMC7820603
AbstractArticlePDF–5.2M
6.
An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets
Huiyuan Zhang, Asaf Madi, Nir Yosef, Norio Chihara, Amit Awasthi, Caroline Pot, Conner Lambden, Amitabh Srivastava, Patrick R. Burkett, Jackson Nyman, Elena Christian, Yasaman Etminan, Annika Lee, Helene Stroh, Junrong Xia, Katarzyna Karwacz, Pratiksha I. Thakore, Nandini Acharya, Alexandra Schnell, Chao Wang, Lionel Apetoh, Orit Rozenblatt-Rosen, Ana C. Anderson, Aviv Regev, Vijay K. Kuchroo
Cell Rep. Author manuscript; available in PMC 2020 Dec 29.
Published in final edited form as: Cell Rep. 2020 Nov 24; 33(8): 108433. doi: 10.1016/j.celrep.2020.108433
PMCID:
PMC7771052
AbstractArticlePDF–2.9M
7.
STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells
Lin Jin, Yunjia Chen, David K. Crossman, Arunima Datta, Trung Vu, James A. Mobley, Malay Kumar Basu, Mariangela Scarduzio, Hengbin Wang, Chenbei Chang, Pran K. Datta
Nat Commun. 2020; 11: 5941. Published online 2020 Nov 23. doi: 10.1038/s41467-020-19698-6
PMCID:
PMC7684319
AbstractArticlePDF–3.4M
8.
Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes
Rajendra Karki, Bhesh Raj Sharma, Shraddha Tuladhar, Evan Peter Williams, Lillian Zalduondo, Parimal Samir, Min Zheng, Balamurugan Sundaram, Balaji Banoth, R.K. Subbarao Malireddi, Patrick Schreiner, Geoffrey Neale, Peter Vogel, Richard Webby, Colleen Beth Jonsson, Thirumala-Devi Kanneganti
Cell. 2021 Jan 7; 184(1): 149–168.e17. Published online 2020 Nov 19. doi: 10.1016/j.cell.2020.11.025
PMCID:
PMC7674074
AbstractArticlePDF–9.9M
9.
The role of Irf6 in tooth epithelial invagination
James Blackburn, Atsushi Ohazama, Katsushige Kawasaki, Yoko Otsuka-Tanaka, Bigang Liu, Kenya Honda, Ryan B. Rountree, Yinling Hu, Maiko Kawasaki, Walter Birchmeier, Ruth Schmidt-Ullrich, Akira Kinoshita, Brian C. Schutte, Nigel L. Hammond, Michael J. Dixon, Paul T. Sharpe
Dev Biol. Author manuscript; available in PMC 2020 Sep 1.
Published in final edited form as: Dev Biol. 2012 May 1; 365(1): 61–70. Published online 2012 Feb 14. doi: 10.1016/j.ydbio.2012.02.009
PMCID:
PMC7462630
AbstractArticlePDF–3.4M
10.
Type I Interferons Ameliorate Zinc Intoxication of Candida glabrata by Macrophages and Promote Fungal Immune Evasion
Michael Riedelberger, Philipp Penninger, Michael Tscherner, Bernhard Hadriga, Carina Brunnhofer, Sabrina Jenull, Anton Stoiber, Christelle Bourgeois, Andriy Petryshyn, Walter Glaser, Andreas Limbeck, Michael A. Lynes, Gernot Schabbauer, Guenter Weiss, Karl Kuchler
iScience. 2020 May 22; 23(5): 101121. Published online 2020 May 4. doi: 10.1016/j.isci.2020.101121
PMCID:
PMC7232100
AbstractArticlePDF–34M
11.
Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion
David E. Place, Benoit Briard, Parimal Samir, Rajendra Karki, Anannya Bhattacharya, Clifford S. Guy, Jennifer L. Peters, Sharon Frase, Peter Vogel, Geoffrey Neale, Masahiro Yamamoto, Thirumala-Devi Kanneganti
PLoS Pathog. 2020 Mar; 16(3): e1008364. Published online 2020 Mar 9. doi: 10.1371/journal.ppat.1008364
PMCID:
PMC7082077
AbstractArticlePDF–6.9M
12.
Specific enhancer selection by IRF3, IRF5 and IRF9 is determined by ISRE half-sites, 5′ and 3′ flanking bases, collaborating transcription factors and the chromatin environment in a combinatorial fashion
Mária Csumita, Attila Csermely, Attila Horvath, Gergely Nagy, Fanny Monori, Loránd Göczi, Hans-Acha Orbea, Walter Reith, Lajos Széles
Nucleic Acids Res. 2020 Jan 24; 48(2): 589–604. Published online 2019 Dec 4. doi: 10.1093/nar/gkz1112
PMCID:
PMC6954429
AbstractArticlePDF–3.9M
13.
EOMES interacts with RUNX3 and BRG1 to promote innate memory cell formation through epigenetic reprogramming
Nicolas Istaces, Marion Splittgerber, Viviana Lima Silva, Muriel Nguyen, Séverine Thomas, Aurore Le, Younes Achouri, Emilie Calonne, Matthieu Defrance, François Fuks, Stanislas Goriely, Abdulkader Azouz
Nat Commun. 2019; 10: 3306. Published online 2019 Jul 24. doi: 10.1038/s41467-019-11233-6
PMCID:
PMC6656725
AbstractArticlePDF–3.3M
14.
The Type I Interferon-α Mediates a More Severe Neurological Disease in the Absence of the Canonical Signaling Molecule Interferon Regulatory Factor 9
Markus J. Hofer, Wen Li, Sue Ling Lim, Iain L. Campbell
J Neurosci. 2010 Jan 20; 30(3): 1149–1157. doi: 10.1523/JNEUROSCI.3711-09.2010
PMCID:
PMC6633112
AbstractArticlePDF–3.2M
15.
A Critical Role for Interferon Regulatory Factor 9 in Cerebral Ischemic Stroke
Hou-Zao Chen, Sen Guo, Zuo-Zhi Li, Yanyun Lu, Ding-Sheng Jiang, Ran Zhang, Hao Lei, Lu Gao, Xiaofei Zhang, Yan Zhang, Lang Wang, Li-Hua Zhu, Mei Xiang, Yan Zhou, Qi Wan, Hailong Dong, De-Pei Liu, Hongliang Li
J Neurosci. 2014 Sep 3; 34(36): 11897–11912. doi: 10.1523/JNEUROSCI.1545-14.2014
PMCID:
PMC6608458
AbstractArticlePDF–7.6M
16.
A molecular switch from STAT2-IRF9 to ISGF3 underlies interferon-induced gene transcription
Ekaterini Platanitis, Duygu Demiroz, Anja Schneller, Katrin Fischer, Christophe Capelle, Markus Hartl, Thomas Gossenreiter, Mathias Müller, Maria Novatchkova, Thomas Decker
Nat Commun. 2019; 10: 2921. Published online 2019 Jul 2. doi: 10.1038/s41467-019-10970-y
PMCID:
PMC6606597
AbstractArticlePDF–2.7M
17.
IRF1 is a transcriptional regulator of ZBP1 promoting NLRP3 inflammasome activation and cell death during influenza virus infection
Teneema Kuriakose, Min Zheng, Geoffrey Neale, Thirumala-Devi Kanneganti
J Immunol. Author manuscript; available in PMC 2019 Apr 25.
Published in final edited form as: J Immunol. 2018 Feb 15; 200(4): 1489–1495. Published online 2018 Jan 10. doi: 10.4049/jimmunol.1701538
PMCID:
PMC6483084
AbstractArticlePDF–1.3M
18.
Detrimental Type I Interferon Signaling Dominates Protective AIM2 Inflammasome Responses during Francisella novicida Infection
Qifan Zhu, Si Ming Man, Rajendra Karki, R.K. Subbarao Malireddi, Thirumala-Devi Kanneganti
Cell Rep. Author manuscript; available in PMC 2018 Oct 28.
Published in final edited form as: Cell Rep. 2018 Mar 20; 22(12): 3168–3174. doi: 10.1016/j.celrep.2018.02.096
PMCID:
PMC6204211
AbstractArticlePDF–1.6M
19.
Non-redundant ISGF3 Components Promote NK Cell Survival in an Auto-regulatory Manner during Viral Infection
Clair D. Geary, Chirag Krishna, Colleen M. Lau, Nicholas M. Adams, Sofia V. Gearty, Yuri Pritykin, Allan R. Thomsen, Christina S. Leslie, Joseph C. Sun
Cell Rep. Author manuscript; available in PMC 2018 Sep 25.
Published in final edited form as: Cell Rep. 2018 Aug 21; 24(8): 1949–1957.e6. doi: 10.1016/j.celrep.2018.07.060
PMCID:
PMC6153266
AbstractArticlePDF–1.6M
20.
IRF8 regulates transcription of Naips for NLRC4 inflammasome activation
Rajendra Karki, Ein Lee, David Place, Parimal Samir, Jayadev Mavuluri, Bhesh Raj Sharma, Arjun Balakrishnan, R. K. Subbarao Malireddi, Rechel Geiger, Qifan Zhu, Geoffrey Neale, Thirumala-Devi Kanneganti
Cell. Author manuscript; available in PMC 2019 May 3.
Published in final edited form as: Cell. 2018 May 3; 173(4): 920–933.e13. Published online 2018 Mar 22. doi: 10.1016/j.cell.2018.02.055
PMCID:
PMC5935577
AbstractArticlePDF–2.0M

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