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Items: 1 to 20 of 32

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
The NERP-4–SNAT2 axis regulates pancreatic β-cell maintenance and function
Weidong Zhang, Ayako Miura, Md Moin Abu Saleh, Koichiro Shimizu, Yuichiro Mita, Ryota Tanida, Satoshi Hirako, Seiji Shioda, Valery Gmyr, Julie Kerr-Conte, Francois Pattou, Chunhuan Jin, Yoshikatsu Kanai, Kazuki Sasaki, Naoto Minamino, Hideyuki Sakoda, Masamitsu Nakazato
Nat Commun. 2023; 14: 8158. Published online 2023 Dec 9. doi: 10.1038/s41467-023-43976-8
PMCID:
PMC10710447
AbstractArticlePDF–4.1M
3.
SLC38A2 and glutamine signalling in cDC1s dictate anti-tumour immunity
Chuansheng Guo, Zhiyuan You, Hao Shi, Yu Sun, Xingrong Du, Gustavo Palacios, Cliff Guy, Sujing Yuan, Nicole M. Chapman, Seon Ah Lim, Xiang Sun, Jordy Saravia, Sherri Rankin, Yogesh Dhungana, Hongbo Chi
Nature. 2023; 620(7972): 200–208. Published online 2023 Jul 5. doi: 10.1038/s41586-023-06299-8
PMCID:
PMC10396969
AbstractArticlePDF–17M
4.
Neutral amino acid transporter SLC38A2 protects renal medulla from hyperosmolarity-induced ferroptosis
Chunxiu Du, Hu Xu, Cong Cao, Jiahui Cao, Yufei Zhang, Cong Zhang, Rongfang Qiao, Wenhua Ming, Yaqing Li, Huiwen Ren, Xiaohui Cui, Zhilin Luan, Youfei Guan, Xiaoyan Zhang
eLife. 2023; 12: e80647. Published online 2023 Feb 1. doi: 10.7554/eLife.80647
PMCID:
PMC9949798
AbstractArticlePDF–3.8M
5.
SLC38A2 provides proline and alanine to regulate postnatal bone mass accrual in mice
Leyao Shen, Yilin Yu, Courtney M. Karner
Front Physiol. 2022; 13: 992679. Published online 2022 Sep 23. doi: 10.3389/fphys.2022.992679
PMCID:
PMC9538353
AbstractArticlePDF–3.3M
6.
SLC38A2 provides proline to fulfill unique synthetic demands arising during osteoblast differentiation and bone formation
Leyao Shen, Yilin Yu, Yunji Zhou, Shondra M Pruett-Miller, Guo-Fang Zhang, Courtney M Karner
eLife. 2022; 11: e76963. Published online 2022 Mar 9. doi: 10.7554/eLife.76963
PMCID:
PMC9007586
AbstractArticlePDF–4.9M
7.
Placenta-specific Slc38a2/SNAT2 knockdown causes fetal growth restriction in mice
Owen R. Vaughan, Katarzyna Maksym, Elena Silva, Kenneth Barentsen, Russel V. Anthony, Thomas L. Brown, Sara L. Hillman, Rebecca Spencer, Anna L. David, Fredrick J. Rosario, Theresa L. Powell, Thomas Jansson
Clin Sci (Lond) 2021 Sep; 135(17): 2049–2066. Published online 2021 Aug 31. doi: 10.1042/CS20210575
PMCID:
PMC8410983
AbstractArticlePDF–1.1M
8.
In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions
Hongling Huang, Peipei Zhou, Jun Wei, Lingyun Long, Hao Shi, Yogesh Dhungana, Nicole M. Chapman, Guotong Fu, Jordy Saravia, Jana L. Raynor, Shaofeng Liu, Gustavo Palacios, Yong-Dong Wang, Chenxi Qian, Jiyang Yu, Hongbo Chi
Cell. Author manuscript; available in PMC 2022 Mar 4.
Published in final edited form as: Cell. 2021 Mar 4; 184(5): 1245–1261.e21. Published online 2021 Feb 25. doi: 10.1016/j.cell.2021.02.021
PMCID:
PMC8101447
AbstractArticlePDF–3.8M
9.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
10.
Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction
Malcolm Eaton, Alastair H. Davies, Jay Devine, Xiang Zhao, David G. Simmons, Elín Maríusdóttir, David R. C. Natale, John R. Matyas, Elizabeth A. Bering, Matthew L. Workentine, Benedikt Hallgrimsson, James C. Cross
PLoS One. 2020; 15(1): e0226735. Published online 2020 Jan 9. doi: 10.1371/journal.pone.0226735
PMCID:
PMC6952106
AbstractArticlePDF–2.7M
11.
Paternal knockout of Slc38a4/SNAT4 causes placental hypoplasia associated with intrauterine growth restriction in mice
Shogo Matoba, Shoko Nakamuta, Kento Miura, Michiko Hirose, Hirosuke Shiura, Takashi Kohda, Nobuaki Nakamuta, Atsuo Ogura
Proc Natl Acad Sci U S A. 2019 Oct 15; 116(42): 21047–21053. Published online 2019 Sep 30. doi: 10.1073/pnas.1907884116
PMCID:
PMC6800347
AbstractArticlePDF–1.8M
12.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
13.
Alterered Placental Function of 11β-HSD2 Knockout Mice
Caitlin S Wyrwoll, Jonathan R Seckl, Megan C Holmes
Endocrinology. Author manuscript; available in PMC 2019 Mar 26.
Published in final edited form as: Endocrinology. 2009 Mar; 150(3): 1287–1293. Published online 2008 Oct 9. doi: 10.1210/en.2008-1100
PMCID:
PMC6435187
AbstractArticlePDF–954K
14.
Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models
Syuji Kurogi, Tomohisa Sekimoto, Taro Funamoto, Tomomi Ota, Shihoko Nakamura, Takuya Nagai, Mai Nakahara, Kumiko Yoshinobu, Kimi Araki, Masatake Araki, Etsuo Chosa
Sci Rep. 2017; 7: 40692. Published online 2017 Jan 20. doi: 10.1038/srep40692
PMCID:
PMC5247747
AbstractArticlePDF–1.9M
15.
A hepatic amino acid/mTOR/S6K-dependent signalling pathway modulates systemic lipid metabolism via neuronal signals
Kenji Uno, Tetsuya Yamada, Yasushi Ishigaki, Junta Imai, Yutaka Hasegawa, Shojiro Sawada, Keizo Kaneko, Hiraku Ono, Tomoichiro Asano, Yoshitomo Oka, Hideki Katagiri
Nat Commun. 2015; 6: 7940. Published online 2015 Aug 13. doi: 10.1038/ncomms8940
PMCID:
PMC4557134
AbstractArticlePDF–1.7M
16.
Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity
Dawid Krokowski, Raul Jobava, Bo-Jhih Guan, Kenneth Farabaugh, Jing Wu, Mithu Majumder, Massimiliano G. Bianchi, Martin D. Snider, Ovidio Bussolati, Maria Hatzoglou
J Biol Chem. 2015 Jul 17; 290(29): 17822–17837. Published online 2015 Jun 3. doi: 10.1074/jbc.M114.636217
PMCID:
PMC4505033
AbstractArticlePDF–4.4M
17.
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt
Jernej Murn, Kathi Zarnack, Yawei J. Yang, Omer Durak, Elisabeth A. Murphy, Sihem Cheloufi, Dilenny M. Gonzalez, Marianna Teplova, Tomaž Curk, Johannes Zuber, Dinshaw J. Patel, Jernej Ule, Nicholas M. Luscombe, Li-Huei Tsai, Christopher A. Walsh, Yang Shi
Genes Dev. 2015 Mar 1; 29(5): 501–512. doi: 10.1101/gad.258483.115
PMCID:
PMC4358403
AbstractArticlePDF–1.4M
18.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M

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