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Select item 110186591.

zDHHC3-mediated S-palmitoylation of SLC9A2 regulates apoptosis in kidney clear cell carcinoma

Xiuyun Zhang, Junpeng Hou, Guangyuan Zhou, Haixia Wang, Zeang Wu

J Cancer Res Clin Oncol. 2024; 150(4): 194. Published online 2024 Apr 15. doi: 10.1007/s00432-024-05737-y

PMCID:: PMC11018659

Abstract Article PDF–7.3M

Select item 107620002.

Cyclical palmitoylation regulates TLR9 signalling and systemic autoimmunity in mice

Hai Ni, Yinuo Wang, Kai Yao, Ling Wang, Jiancheng Huang, Yongfang Xiao, Hongyao Chen, Bo Liu, Cliff Y. Yang, Jijun Zhao

Nat Commun. 2024; 15: 1. Published online 2024 Jan 2. doi: 10.1038/s41467-023-43650-z

PMCID:: PMC10762000

Abstract Article PDF–2.7M

Select item 105586853.

IFI27 Integrates Succinate and Fatty Acid Oxidation to Promote Adipocyte Thermogenic Adaption

Xuan Cui, Haojie Liu, Ting Shi, Qingwen Zhao, Feiyan Li, Wenjing Lv, Chao Yu, Haiyan Huang, Qi‐Qun Tang, Dongning Pan

Adv Sci (Weinh) 2023 Oct; 10(28): 2301855. Published online 2023 Aug 6. doi: 10.1002/advs.202301855

PMCID:: PMC10558685

Abstract Article PDF–5.6M

Select item 93325734.

Structural Exploration on Palmitoyltransferase DHHC3 from Homo sapiens

Meng Tang, Ying Xia, Taoran Xiao, Ruiyu Cao, Yu Cao, Bo Ouyang

Polymers (Basel) 2022 Aug; 14(15): 3013. Published online 2022 Jul 26. doi: 10.3390/polym14153013

PMCID:: PMC9332573

Abstract Article PDF–1.7M

Select item 91197365.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 89515566.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Abstract Article PDF–4.4M

Select item 87519807.

Antioxidant functions of DHHC3 suppress anti-cancer drug activities

Chandan Sharma, Wei Yang, Hanno Steen, Michael R. Freeman, Martin E. Hemler

Cell Mol Life Sci. 2021 Mar; 78(5): 2341–2353. Published online 2020 Sep 28. doi: 10.1007/s00018-020-03635-3

PMCID:: PMC8751980

Abstract Article PDF–5.4M

Select item 85275788.

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity

Yuehui Zhang, Limin Shang, Jing Zhang, Yuchen Liu, Chaozhi Jin, Yanan Zhao, Xiaobo Lei, Wenjing Wang, Xia Xiao, Xiuyuan Zhang, Yujiao Liu, Linlin Liu, Meng-Wei Zhuang, Qingkun Mi, Chunyan Tian, Jianwei Wang, Fuchu He, Pei-Hui Wang, Jian Wang

Cell Chem Biol. 2022 Jan 20; 29(1): 5–18.e6. Published online 2021 Oct 20. doi: 10.1016/j.chembiol.2021.10.008

PMCID:: PMC8527578

Abstract Article PDF–4.5M

Select item 85138539.

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation

Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari

PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412

PMCID:: PMC8513853

Abstract Article PDF–4.1M

Select item 837982210.

S-acylation of SARS-CoV-2 spike protein: Mechanistic dissection, in vitro reconstitution and role in viral infectivity

Robbins Puthenveetil, Cheng Man Lun, R. Elliot Murphy, Liam B. Healy, Geraldine Vilmen, Eric T. Christenson, Eric O. Freed, Anirban Banerjee

J Biol Chem. 2021 Oct; 297(4): 101112. Published online 2021 Aug 21. doi: 10.1016/j.jbc.2021.101112

PMCID:: PMC8379822

Abstract Article PDF–2.7M

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 581988312.

Protein Acyltransferase DHHC3 Regulates Breast Tumor Growth, Oxidative Stress, and Senescence

Chandan Sharma, Hong-Xing Wang, Qinglin Li, Konstantin Knoblich, Emily S. Reisenbichler, Andrea L. Richardson, Martin E. Hemler

Cancer Res. Author manuscript; available in PMC 2018 Feb 20.

Published in final edited form as: Cancer Res. 2017 Dec 15; 77(24): 6880–6890. Published online 2017 Oct 20. doi: 10.1158/0008-5472.CAN-17-1536

PMCID:: PMC5819883

Abstract Article PDF–2.3M

Select item 559975313.

Binding of Herpes Simplex Virus 1 UL20 to GODZ (DHHC3) Affects Its Palmitoylation and Is Essential for Infectivity and Proper Targeting and Localization of UL20 and Glycoprotein K

Shaohui Wang, Kevin R. Mott, Kolja Wawrowsky, Konstantin G. Kousoulas, Bernhard Luscher, Homayon Ghiasi

J Virol. 2017 Oct 1; 91(19): e00945-17. Prepublished online 2017 Jul 19. Published online 2017 Sep 12. doi: 10.1128/JVI.00945-17

PMCID:: PMC5599753

Abstract Article PDF–2.5M

Select item 537173014.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430