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Select item 110912831.

Myeloid cell expression of CD200R is modulated in active TB disease and regulates Mycobacterium tuberculosis infection in a biomimetic model

Mohamed Ahmed, Liku B. Tezera, Nicholas Herbert, Mark Chambers, Michaela T. Reichmann, Kievershen Nargan, Henrik Kloverpris, Farina Karim, Mbali Hlatshwayo, Rajhmun Madensein, Munir Habesh, Monjural Hoque, Adrie J.C. Steyn, Paul T. Elkington, Alasdair J. Leslie

Front Immunol. 2024; 15: 1360412. Published online 2024 Apr 30. doi: 10.3389/fimmu.2024.1360412

PMCID:: PMC11091283

Abstract Article PDF–3.3M

Select item 108623662.

Exploiting the CD200-CD200R immune checkpoint axis in multiple myeloma to enhance CAR T-cell therapy

Yan Tang, Wei Liu, Siddhant Kadu, Omar Johnson, Zainul S. Hasanali, Andre Kelly, Alexander Shestov, Raymone Pajarillo, Eli Greenblatt, Matthew Holmes, Li-Ping Wang, Natalie Shih, Roddy S. O’Connor, Marco Ruella, Alfred L. Garfall, David Allman, Dan T. Vogl, Adam Cohen, Carl H. June, Neil C. Sheppard

Blood. 2024 Jan 11; 143(2): 139–151. Published online 2023 Aug 26. doi: 10.1182/blood.2022018658

PMCID:: PMC10862366

Abstract Article

Select item 89473383.

The Role of CD200–CD200 Receptor in Human Blood and Lymphatic Endothelial Cells in the Regulation of Skin Tissue Inflammation

Dominic Rütsche, Katarzyna Michalak-Micka, Dominika Zielinska, Hannah Moll, Ueli Moehrlen, Thomas Biedermann, Agnes S. Klar

Cells. 2022 Mar; 11(6): 1055. Published online 2022 Mar 21. doi: 10.3390/cells11061055

PMCID:: PMC8947338

Abstract Article PDF–5.2M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80070305.

Identification of a novel conserved signaling motif in CD200 receptor required for its inhibitory function

Laura M. Timmerman, J. Fréderique de Graaf, Nikolaos Satravelas, Çan Kesmir, Linde Meyaard, Michiel van der Vlist

PLoS One. 2021; 16(3): e0244770. Published online 2021 Mar 29. doi: 10.1371/journal.pone.0244770

PMCID:: PMC8007030

Abstract Article PDF–2.3M

Select item 73391066.

CD200-CD200R pathway in the regulation of tumor immune microenvironment and immunotherapy

Jin-Qing Liu, Aiyan Hu, Jianmin Zhu, Jianyu Yu, Fatemeh Talebian, Xue-Feng Bai

Adv Exp Med Biol. Author manuscript; available in PMC 2021 Jan 1.

Published in final edited form as: Adv Exp Med Biol. 2020; 1223: 155–165. doi: 10.1007/978-3-030-35582-1_8

PMCID:: PMC7339106

Abstract Article PDF–1.4M

Select item 71699837.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 57097848.

A CD200R-CD28 fusion protein appropriates an inhibitory signal to enhance T-cell function and therapy of murine leukemia

Shannon K. Oda, Andrew W. Daman, Nicolas M. Garcia, Felecia Wagener, Thomas M. Schmitt, Xiaoxia Tan, Aude G. Chapuis, Philip D. Greenberg

Blood. 2017 Nov 30; 130(22): 2410–2419. Prepublished online 2017 Oct 17. doi: 10.1182/blood-2017-04-777052

PMCID:: PMC5709784

Abstract Article

Select item 54781749.

Herpesvirus orthologues of CD200 bind host CD200R but not related activating receptors

Lai Shan Kwong, Munir Akkaya, A. Neil Barclay, Deborah Hatherley

J Gen Virol. 2016 Jan; 97(Pt 1): 179–184. Published online 2016 Jan 1. doi: 10.1099/jgv.0.000335

PMCID:: PMC5478174

Abstract Article PDF–335K

Select item 514413310.

Reduced expression of monocyte CD200R is associated with enhanced proinflammatory cytokine production in sarcoidosis

Simon D. Fraser, Laura R. Sadofsky, Paul M. Kaye, Simon P. Hart

Sci Rep. 2016; 6: 38689. Published online 2016 Dec 8. doi: 10.1038/srep38689

PMCID:: PMC5144133

Abstract Article PDF–1.3M

Select item 497595311.

A critical role of CD200R signaling in limiting the growth and metastasis of CD200 positive melanoma

Jin-Qing Liu, Fatemeh Talebian, Lisha Wu, Zhihao Liu, Ming-Song Li, Laichu Wu, Jianmin Zhu, Joseph Markowitz, William E. Carson, III, Sujit Basu, Xue-Feng Bai

J Immunol. Author manuscript; available in PMC 2017 Aug 15.

Published in final edited form as: J Immunol. 2016 Aug 15; 197(4): 1489–1497. Published online 2016 Jul 6. doi: 10.4049/jimmunol.1600052

PMCID:: PMC4975953

Abstract Article PDF–777K

Select item 469109012.

Reduced Dendritic Cells Expressing CD200R1 in Children with Inflammatory Bowel Disease: Correlation with Th17 and Regulatory T Cells

Mohamed F. Elshal, Alia M. Aldahlawi, Omar I. Saadah, J. Philip McCoy

Int J Mol Sci. 2015 Dec; 16(12): 28998–29010. Published online 2015 Dec 4. doi: 10.3390/ijms161226143

PMCID:: PMC4691090

Abstract Article PDF–1.4M

Select item 464794113.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 461768414.

The CD200–CD200R1 Inhibitory Signaling Pathway: Immune Regulation and Host–Pathogen Interactions

Christine A. Vaine, Roy J. Soberman

Adv Immunol. 2014; 121: 191–211. Published online 2013 Dec 31. doi: 10.1016/B978-0-12-800100-4.00005-2

PMCID:: PMC4617684

Abstract Article PDF–348K

Select item 461721115.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 373381716.

CD200R/CD200 Inhibits Osteoclastogenesis: New Mechanism of Osteoclast Control by Mesenchymal Stem Cells in Human

Audrey Varin, Charalampos Pontikoglou, Elodie Labat, Frédéric Deschaseaux, Luc Sensebé

PLoS One. 2013; 8(8): e72831. Published online 2013 Aug 5. doi: 10.1371/journal.pone.0072831

PMCID:: PMC3733817

Abstract Article PDF–2.2M

Select item 358195417.

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins

Rajesh Ghai, Andrea Bugarcic, Huadong Liu, Suzanne J. Norwood, Sune Skeldal, Elizabeth J. Coulson, Shawn Shun-Cheng Li, Rohan D. Teasdale, Brett M. Collins

Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8): E643–E652. Published online 2013 Feb 4. doi: 10.1073/pnas.1216229110

PMCID:: PMC3581954

Abstract Article PDF–2.3M

Select item 344650418.

Aberrant CD200/CD200R1 expression and function in systemic lupus erythematosus contributes to abnormal T-cell responsiveness and dendritic cell activity

Yang Li, Li-dan Zhao, Lu-sha Tong, Su-ning Qian, Yan Ren, Lei Zhang, Xin Ding, Yang Chen, Yan-xia Wang, Wen Zhang, Xiao-feng Zeng, Feng-chun Zhang, Fu-lin Tang, Xuan Zhang, De-nian Ba, Wei He, Xue-tao Cao, Peter E Lipsky

Arthritis Res Ther. 2012; 14(3): R123. Published online 2012 May 23. doi: 10.1186/ar3853

PMCID:: PMC3446504

Abstract Article PDF–1.1M

Select item 337219419.

Suppression of Antigen-Specific T Cell Responses by the Kaposi's Sarcoma-Associated Herpesvirus Viral OX2 Protein and Its Cellular Orthologue, CD200

Karen Misstear, Simon A. Chanas, S. A. Rahim Rezaee, Rachel Colman, Laura L. Quinn, Heather M. Long, Oliver Goodyear, Janet M. Lord, Andrew D. Hislop, David J. Blackbourn

J Virol. 2012 Jun; 86(11): 6246–6257. doi: 10.1128/JVI.07168-11

PMCID:: PMC3372194

Abstract Article PDF–1.8M

Select item 336143620.

The genetic architecture of economic and political preferences

Daniel J. Benjamin, David Cesarini, Matthijs J. H. M. van der Loos, Christopher T. Dawes, Philipp D. Koellinger, Patrik K. E. Magnusson, Christopher F. Chabris, Dalton Conley, David Laibson, Magnus Johannesson, Peter M. Visscher

Proc Natl Acad Sci U S A. 2012 May 22; 109(21): 8026–8031. Published online 2012 May 7. doi: 10.1073/pnas.1120666109

PMCID:: PMC3361436

Abstract Article PDF–128K

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