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Items: 1 to 20 of 42

1.
Extensive Molecular and Clinical Heterogeneity in Patients With Histologically Diagnosed CNS-PNET Treated as a Single Entity: A Report From the Children’s Oncology Group Randomized ACNS0332 Trial
Eugene I. Hwang, Marcel Kool, Peter C. Burger, David Capper, Lukas Chavez, Sebastian Brabetz, Chris Williams-Hughes, Catherine Billups, Linda Heier, Alok Jaju, Jeff Michalski, Yimei Li, Sarah Leary, Tianni Zhou, Andreas von Deimling, David T.W. Jones, Maryam Fouladi, Ian F. Pollack, Amar Gajjar, Roger J. Packer, Stefan M. Pfister, James M. Olson
J Clin Oncol. 2018 Dec 1; 36(34): 3388–3395. Published online 2018 Oct 17. doi: 10.1200/JCO.2017.76.4720
PMCID:
PMC9153369
AbstractArticlePDF–930K
2.
Taste and smell function in long-term survivors after childhood medulloblastoma/CNS-PNET
Kristine Eidal Tanem, Einar Stensvold, Petter Wilberg, Anne B. Skaare, Preet Bano Singh, Petter Brandal, Bente Brokstad Herlofson
Support Care Cancer. 2022; 30(7): 6155–6162. Published online 2022 Apr 15. doi: 10.1007/s00520-022-07048-9
PMCID:
PMC9135811
AbstractArticlePDF–702K
3.
Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation
Andrey Korshunov, Konstantin Okonechnikov, Felix Schmitt-Hoffner, Marina Ryzhova, Felix Sahm, Damian Stichel, Daniel Schrimpf, David E. Reuss, Philipp Sievers, Abigail Kora Suwala, Ella Kumirova, Olga Zheludkova, Andrey Golanov, David T. W. Jones, Stefan M. Pfister, Marcel Kool, Andreas von Deimling
Acta Neuropathol Commun. 2021; 9: 20. Published online 2021 Feb 3. doi: 10.1186/s40478-021-01118-5
PMCID:
PMC7860633
AbstractArticlePDF–7.0M
4.
Case Report: A Unique Case of Pediatric Central Nervous System Embryonal Tumor Harboring the CIC–LEUTX Fusion, Germline NBN Variant and Somatic TSC2 Mutation: Expanding the Spectrum of CIC-Rearranged Neoplasia
Wanming Hu, Juan Wang, Li Yuan, Xing Zhang, Yuhang Ji, Chao Song, Jing Zeng, Xiaofei Sun
Front Oncol. 2020; 10: 598970. Published online 2020 Dec 2. doi: 10.3389/fonc.2020.598970
PMCID:
PMC7738346
AbstractArticlePDF–6.4M
5.
Estrogen and soy isoflavonoids decrease sensitivity of medulloblastoma and central nervous system primitive neuroectodermal tumor cells to chemotherapeutic cytotoxicity
Scott M. Belcher, Caleb C. Burton, Clifford J. Cookman, Michelle Kirby, Gabriel L. Miranda, Fatima O. Saeed, Kathleen E. Wray
BMC Pharmacol Toxicol. 2017; 18: 63. Published online 2017 Sep 6. doi: 10.1186/s40360-017-0160-7
PMCID:
PMC5585986
AbstractArticlePDF–2.1M
6.
Stabilization of HIF-1α and HIF-2α, up-regulation of MYCC and accumulation of stabilized p53 constitute hallmarks of CNS-PNET animal model
Sergey Malchenko, Simone Treiger Sredni, Yingtao Bi, Naira V. Margaryan, Jerusha Boyineni, Indra Mohanam, Tadanori Tomita, Ramana V. Davuluri, Marcelo B. Soares
PLoS One. 2017; 12(3): e0173106. Published online 2017 Mar 1. doi: 10.1371/journal.pone.0173106
PMCID:
PMC5332108
AbstractArticlePDF–2.8M
7.
Genome-wide molecular characterization of central nervous system primitive neuroectodermal tumor and pineoblastoma
Suzanne Miller, Hazel A. Rogers, Paul Lyon, Vikki Rand, Martyna Adamowicz-Brice, Steven C. Clifford, James T. Hayden, Sara Dyer, Stefan Pfister, Andrey Korshunov, Marie-Anne Brundler, James Lowe, Beth Coyle, Richard G. Grundy
Neuro Oncol. 2011 Aug; 13(8): 866–879. Published online 2011 Jul 20. doi: 10.1093/neuonc/nor070
PMCID:
PMC3145471
AbstractArticlePDF–454K
8.
An investigation of WNT pathway activation and association with survival in central nervous system primitive neuroectodermal tumours (CNS PNET)
H A Rogers, S Miller, J Lowe, M-A Brundler, B Coyle, R G Grundy
Br J Cancer. 2009 Apr 21; 100(8): 1292–1302. Published online 2009 Mar 17. doi: 10.1038/sj.bjc.6604979
PMCID:
PMC2676550
AbstractArticlePDF–386K
9.
Molecular classification and outcome of children with rare CNS embryonal tumors: Results from St. Jude Children’s Research Hospital including the multi-center SJYC07 and SJMB03 clinical trials
Anthony P.Y. Liu, Sandeep K. Dhanda, Tong Lin, Edgar Sioson, Aksana Vasilyeva, Brian Gudenas, Ruth G. Tatevossian, Sujuan Jia, Geoffrey Neale, Daniel C. Bowers, Tim Hassall, Sonia Partap, John R. Crawford, Murali Chintagumpala, Eric Bouffet, Geoff McCowage, Alberto Broniscer, Ibrahim Qaddoumi, Greg Armstrong, Karen D. Wright, Santhosh A. Upadhyaya, Anna Vinitsky, Christopher L. Tinkle, John Lucas, Jason Chiang, Daniel J. Indelicato, Robert Sanders, Paul Klimo, Jr, Frederick A. Boop, Thomas E. Merchant, David W. Ellison, Paul A. Northcott, Brent A. Orr, Xin Zhou, Arzu Onar-Thomas, Amar Gajjar, Giles W. Robinson
Acta Neuropathol. Author manuscript; available in PMC 2023 Sep 6.
Published in final edited form as: Acta Neuropathol. 2022 Oct; 144(4): 733–746. Published online 2022 Aug 18. doi: 10.1007/s00401-022-02484-7
PMCID:
PMC10482085
AbstractArticlePDF–1.6M
10.
Supratentorial CNS-PNETs in children; a Swedish population-based study with molecular re-evaluation and long-term follow-up
Elizabeth Schepke, Maja Löfgren, Torsten Pietsch, Teresia Kling, Claes Nordborg, Thomas Olsson Bontell, Stefan Holm, Anders Öberg, Per Nyman, Marie Eliasson-Hofvander, Magnus Sabel, Birgitta Lannering, Helena Carén
Clin Epigenetics. 2023; 15: 40. Published online 2023 Mar 9. doi: 10.1186/s13148-023-01456-2
PMCID:
PMC9996973
AbstractArticlePDF–5.2M
11.
Therapeutic implications of improved molecular diagnostics for rare CNS embryonal tumor entities: results of an international, retrospective study
Katja von Hoff, Christine Haberler, Felix Schmitt-Hoffner, Elizabeth Schepke, Teresa de Rojas, Sandra Jacobs, Michal Zapotocky, David Sumerauer, Marta Perek-Polnik, Christelle Dufour, Dannis van Vuurden, Irene Slavc, Johannes Gojo, Jessica C Pickles, Nicolas U Gerber, Maura Massimino, Maria Joao Gil-da-Costa, Miklos Garami, Ella Kumirova, Astrid Sehested, David Scheie, Ofelia Cruz, Lucas Moreno, Jaeho Cho, Bernward Zeller, Niels Bovenschen, Michael Grotzer, Daniel Alderete, Matija Snuderl, Olga Zheludkova, Andrey Golanov, Konstantin Okonechnikov, Martin Mynarek, Björn Ole Juhnke, Stefan Rutkowski, Ulrich Schüller, Barry Pizer, Barbara von Zezschwitz, Robert Kwiecien, Maximilian Wechsung, Frank Konietschke, Eugene I Hwang, Dominik Sturm, Stefan M Pfister, Andreas von Deimling, Elisabeth J Rushing, Marina Ryzhova, Peter Hauser, Maria Łastowska, Pieter Wesseling, Felice Giangaspero, Cynthia Hawkins, Dominique Figarella-Branger, Charles Eberhart, Peter Burger, Marco Gessi, Andrey Korshunov, Tom S Jacques, David Capper, Torsten Pietsch, Marcel Kool
Neuro Oncol. 2021 Sep; 23(9): 1597–1611. Published online 2021 Jun 2. doi: 10.1093/neuonc/noab136
PMCID:
PMC8408859
AbstractArticlePDF–1.6M
12.
Central Nervous System Primitive Neuroectodermal Tumors: A Clinicopathologic and Genetic Study of 33 Cases
Amir Behdad, Arie Perry
Brain Pathol. 2010 Mar; 20(2): 441–450. Published online 2009 Jun 25. doi: 10.1111/j.1750-3639.2009.00314.x
PMCID:
PMC8094730
AbstractArticlePDF–1.1M
13.
Loss of INI1 Protein Expression Defines a Subgroup of Aggressive Central Nervous System Primitive Neuroectodermal Tumors
Suzanne Miller, Jennifer H. Ward, Hazel A. Rogers, James Lowe, Richard G. Grundy
Brain Pathol. 2013 Jan; 23(1): 19–27. Published online 2012 Jun 25. doi: 10.1111/j.1750-3639.2012.00610.x
PMCID:
PMC8028905
AbstractArticlePDF–613K
14.
The oncolytic adenovirus VCN-01 promotes anti-tumor effect in primitive neuroectodermal tumor models
Marc Garcia-Moure, Naiara Martinez-Velez, Marisol Gonzalez-Huarriz, Lucía Marrodán, Manel Cascallo, Ramón Alemany, Ana Patiño-García, Marta M. Alonso
Sci Rep. 2019; 9: 14368. Published online 2019 Oct 7. doi: 10.1038/s41598-019-51014-1
PMCID:
PMC6779892
AbstractArticlePDF–1.6M
15.
Sleeping Beauty insertional mutagenesis reveals important genetic drivers of central nervous system embryonal tumors.
Pauline J. Beckmann, Jon D. Larson, Alex T. Larsson, Jason P. Ostergaard, Sandra Wagner, Eric P. Rahrmann, Ghaidan A. Shamsan, George M. Otto, Rory L. Williams, Jun Wang, Catherine Lee, Barbara R. Tschida, Paramita Das, Adrian M. Dubuc, Branden S. Moriarity, Daniel Picard, Xiaochong Wu, Fausto J. Rodriguez, Quincy Rosemarie, Ryan D. Krebs, Amy M. Molan, Addison M. Demer, Michelle M. Frees, Anthony E. Rizzardi, Stephen C. Schmechel, Charles G. Eberhart, Robert B. Jenkins, Robert J. Wechsler-Reya, David J. Odde, Annie Huang, Michael D. Taylor, Aaron L. Sarver, David A. Largaespada
Cancer Res. Author manuscript; available in PMC 2020 Mar 1.
Published in final edited form as: Cancer Res. 2019 Mar 1; 79(5): 905–917. Published online 2019 Jan 23. doi: 10.1158/0008-5472.CAN-18-1261
PMCID:
PMC6397665
AbstractArticlePDF–3.8M
16.
Epigenetic regulators Rbbp4 and Hdac1 are overexpressed in a zebrafish model of RB1 embryonal brain tumor, and are required for neural progenitor survival and proliferation
Laura E. Schultz, Jeffrey A. Haltom, Maira P. Almeida, Wesley A. Wierson, Staci L. Solin, Trevor J. Weiss, Jordan A. Helmer, Elizabeth J. Sandquist, Heather R. Shive, Maura McGrail
Dis Model Mech. 2018 Jun 1; 11(6): dmm034124. Published online 2018 Jun 15. doi: 10.1242/dmm.034124
PMCID:
PMC6031359
AbstractArticle
17.
A novel C19MC amplified cell line links Lin28/let-7 to mTOR signaling in embryonal tumor with multilayered rosettes
Tara Spence, Christian Perotti, Patrick Sin-Chan, Daniel Picard, Wei Wu, Anjali Singh, Colleen Anderson, Michael D. Blough, J. Gregory Cairncross, Lucie Lafay-Cousin, Douglas Strother, Cynthia Hawkins, Aru Narendran, Annie Huang, Jennifer A. Chan
Neuro Oncol. 2014 Jan; 16(1): 62–71. Published online 2013 Dec 4. doi: 10.1093/neuonc/not162
PMCID:
PMC3870842
AbstractArticlePDF–1.9M
18.
The role of the WNT/β-catenin pathway in central nervous system primitive neuroectodermal tumours (CNS PNETs)
H A Rogers, J H Ward, S Miller, J Lowe, B Coyle, R G Grundy
Br J Cancer. 2013 May 28; 108(10): 2130–2141. Published online 2013 Apr 16. doi: 10.1038/bjc.2013.170
PMCID:
PMC3670474
AbstractArticlePDF–2.0M
19.
Integrative genomic analyses identify LIN28 and OLIG2 as markers of survival and metastatic potential in childhood central nervous system primitive neuro-ectodermal brain tumours
Daniel Picard, Suzanne Miller, Cynthia E Hawkins, Eric Bouffet, Hazel A Rogers, Tiffany SY Chan, Seung-Ki Kim, Young-Shin Ra, Jason Fangusaro, Andrey Korshunov, Helen Toledano, Hideo Nakamura, James T Hayden, Jennifer Chan, Lucie Lafay-Cousin, Ping X Hu, Xing Fan, Karin M Muraszko, Scott L Pomeroy, Ching C Lau, Ho-Keung Ng, Chris Jones, Timothy Van Meter, Steven C Clifford, Charles Eberhart, Amar Gajjar, Stefan M Pfister, Richard G Grundy, Annie Huang
Lancet Oncol. Author manuscript; available in PMC 2013 Apr 3.
Published in final edited form as: Lancet Oncol. 2012 Aug; 13(8): 838–848. doi: 10.1016/S1470-2045(12)70257-7
PMCID:
PMC3615440
AbstractArticlePDF–1.6M
20.
Frequent amplification of a chr19q13.41 microRNA polycistron (C19MC) in aggressive primitive neuro-ectodermal brain tumors
Meihua Li, Kyle F Lee, Yuntao Lu, Ian Clarke, David Shih, Charles Eberhart, V. Peter Collins, Tim Van Meter, Daniel Picard, Limei Zhou, Paul Boutros, Piergiorgio Modeno, Muh-Lii Liang, Steve W Scherer, Eric Bouffet, James T Rutka, Scott L. Pomeroy, Ching C Lau, Michael D Taylor, Amar Gajjar, Peter B Dirks, Cynthia E Hawkins, Annie Huang
Cancer Cell. Author manuscript; available in PMC 2012 Aug 31.
Published in final edited form as: Cancer Cell. 2009 Dec 8; 16(6): 533–546. doi: 10.1016/j.ccr.2009.10.025
Correction in:
volume 17 on page 413
PMCID:
PMC3431561
AbstractArticlePDF–2.9M

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